Vascular Protective Effects of Morinda citrifolia Leaf Extract on Postmenopausal Rats Fed with Thermoxidized Palm Oil Diet: Evidence at Microscopic Level by C. L. G. Chong, Faizah Othman, Farida Hussan

“…Atherosclerosis is now well understood as an inflammatory disease instead of lipid storage disorder; however, the conventional treatment is not targeted on treating the inflammation. …”
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Update on the Role of Cannabinoid Receptors after Ischemic Stroke by Luciano S. A. Capettini, Silvia Q. Savergnini, Rafaela F. da Silva, Nikos Stergiopulos, Robson A. S. Santos, François Mach, Fabrizio Montecucco

“…Cannabinoids are considered as key mediators in the pathophysiology of inflammatory diseases, including atherosclerosis. In particular, they have been shown to reduce the ischemic injury after acute cardiovascular events, such as acute myocardial infarction and ischemic stroke. …”
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Lipofundin-Induced Hyperlipidemia Promotes Oxidative Stress and Atherosclerotic Lesions in New Zealand White Rabbits by Livan Delgado Roche, Emilio Acosta Medina, Ángela Fraga Pérez, María A. Bécquer Viart, Yosdel Soto López, Viviana Falcón Cama, Ana M. Vázquez López, Gregorio Martínez-Sánchez, Eduardo Fernández-Sánchez

“…Atherosclerosis represents a major cause of death in the world. …”
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Influence of Synthetic Antioxidants Used in Food Technology on the Bioavailability and Metabolism of Lipids - In Vitro Studies by Magdalena Mika, Anna Antończyk, Agnieszka Wikiera

“…The large CMRs generated for samples with BHA were not absorbed by hepatocytes, which can lead to atherosclerosis. The results of our in vitro study shed new light on the role of synthetic phenolic antioxidants used in food technology as potential obesity and atherosclerosis triggers and suggested the need for further research that will clearly separate antioxidants that promote the development of these diseases from those, which do not do that.…”
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Nε-Carboxymethyl-Lysine Negatively Regulates Foam Cell Migration via the Vav1/Rac1 Pathway by Zhengyang Bao, Lili Zhang, Lihua Li, Jinchuan Yan, Qiwen Pang, Zhen Sun, Yue Geng, Lele Jing, Chen Shao, Zhongqun Wang

“…Macrophage-derived foam cells play a central role in atherosclerosis, and their ultimate fate includes apoptosis, promotion of vascular inflammation, or migration to other tissues. …”
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Rare variants in previously identified linkage regions associated with carotid plaque in Dominican Republic families. by Nicole D Dueker, Ashley Beecham, Liyong Wang, Chuanhui Dong, Ralph L Sacco, Susan H Blanton, Tatjana Rundek

“…Carotid plaque is a subclinical measure of atherosclerosis. We have previously shown measures of carotid plaque to be heritable in a sample of 100 Dominican families and found evidence for linkage and association of common variants (CVs) on 7q36, 11p15, 14q32 and 15q23 with plaque presence. …”
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miR-149 Alleviates Ox-LDL-Induced Endothelial Cell Injury by Promoting Autophagy through Akt/mTOR Pathway by Zhongsheng Zhu, Jinyu Li, Rui Tong, Xiaorong Zhang, Bo Yu

“…Background. Atherosclerosis is a chronic process that takes place in the vascular wall and causes various cardiovascular diseases (CVDs). …”
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Remote and Anesthetic-Induced Myocardial Preconditioning Is Preserved in Atherosclerotic LDL Receptor-/- Mice In Vivo by Walter Petermichl, Kathrin Eglmeier, Henriette Hesse, Michael Gruber, Bernhard Graf, Andre Bredthauer, Andreas Redel

“…Histopathological examination showed atherosclerosis in high-fat atherogenic fed LDLR-/- mice, and the vessel relaxation capacity was significantly reduced compared to wild-type mice. …”
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PPAR-δ in Vascular Pathophysiology by Nanping Wang

“…Therefore, it is suggested that PPAR-δ may have critical roles in cardiovascular pathophysiology and is a potential target for therapeutic intervention of cardiovascular disorders such as atherosclerosis.…”
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Numerical Simulation of Particle Deposition in Arterial Bifurcation via Lattice Boltzmann Method by Houhui Yi

“…The study provides a basis for understanding the mechanism of hemodynamics near bifurcations and will provide a research basis for clinical diagnosis and treatment of patients with atherosclerosis.…”
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Immune and Inflammation in Acute Coronary Syndrome: Molecular Mechanisms and Therapeutic Implications by Haiming Wang, Zifan Liu, Junjie Shao, Lejian Lin, Min Jiang, Lin Wang, Xuechun Lu, Haomin Zhang, Yundai Chen, Ran Zhang

“…Both innate and adaptive immunity regulate atherosclerosis progression, plaque stability, and thrombus formation. …”
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Electronegative LDL from Rabbits Fed with Atherogenic Diet Is Highly Proinflammatory by Po-Yuan Chang, Jou-Hsiang Pai, Yu-Sheng Lai, Shao-Chun Lu

“…Electronegative low-density lipoprotein (LDL(-)) has been found in the plasma of familial hypercholesterolemia and acute myocardial infarction and has been implicated in atherosclerosis and cardiovascular disease. However, less is known about the involvement of LDL(-) in atherosclerosis-related inflammation. …”
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Fenofibrate Inhibited the Differentiation of T Helper 17 Cells In Vitro by Zhou Zhou, Weiliang Sun, Ying Liang, Yanxiang Gao, Wei Kong, Youfei Guan, Juan Feng, Xian Wang

“…Previous papers have revealed that a lipid-lowering synthetic ligand of peroxisome proliferator-activated receptor α (PPARα), fenofibrate, alleviates both atherosclerosis and a few nonlipid-associated autoimmune diseases such as autoimmune colitis and multiple sclerosis. …”
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Peroxisome Proliferator-Activated Receptor-γ Antagonizes LOX-1-Mediated Endothelial Injury by Transcriptional Activation of miR-590-5p by Lei Xu, Gang Zhao, Hong Zhu, Shijun Wang, Aijun Sun, Yunzeng Zou, Junbo Ge

“…Collectively, these data indicated that PPAR-γ may have the therapeutic potential in atherosclerosis via the transcriptional regulation of miR-590-5p in endothelial cells.…”
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Impact of duration of treatments with metformin and sulfonylureas, individually or in combination, on diabetic retinopathy among newly diagnosed type 2 diabetic patients: a pooled... by Mansour Bahardoust, Yadollah Mehrabi, Farzad Hadaegh, Davood Khalili, Ali Delpisheh

“…Methods The data of 4,068 newly diagnosed DM individuals(mean age, 60.2 ± 0.85 years) from three prospective cohorts of Tehran Sugar and Lipid Study (TLGS), Multi-Ethnic Study of Atherosclerosis (MESA), and Atherosclerosis Risk in Communities (ARIC) with a mean age of 59.6 ± 08 years were pooled. …”
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Plasmacytoid Dendritic Cells: From Heart to Vessels by Rosalinda Sorrentino, Silvana Morello, Aldo Pinto

“…pDCs populate the vessel wall layers during pathological conditions, such as atherosclerosis. It is thus clear that a better identification of pDCs activity in cardiovascular diseases can not only elucidate pathological mechanisms but also lead to new therapeutic approaches.…”
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In Search of the Genes of Asthma on the Island of Tristan da Cunha by Noe Zamel

“…Asthma, like several common diseases such as diabetes and atherosclerosis, occurs in families and thus probably has a complex polygenic basis, in which environmental factors also play a role. …”
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Diet and the Role of Altered Carbohydrate Absorption in the Treatment of Noninsulin-Dependent Diabetes Mellitus by Thomas MS Wolever

“…Studies suggest that for patients with NIDDM, a calorie-restricted, high carbohydrate diet low in fat and rich in fibre may improve glycemic control, mitigate the risk of atherosclerosis and retard such diabetic complications as nephropathy and retinopathy. …”
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Exploring the Relationship of Perivascular Adipose Tissue Inflammation and the Development of Vascular Pathologies by Afifah Zahirah Abd Rami, Adila A. Hamid, Nur Najmi Mohamad Anuar, Amilia Aminuddin, Azizah Ugusman

“…In this review, current knowledge on the role of PVAT inflammation in the development of vascular pathologies such as atherosclerosis and hypertension was discussed.…”
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The Bioactivities of Phycocyanobilin from Spirulina by Yi Li

“…Due to the above biological activities of phycocyanobilin PCB, it is expected to become a new effective drug for treating various diseases, such as COVID-19 complications, atherosclerosis, multiple sclerosis (MS), and ischaemic stroke (IS).…”
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