Quantification and correlation of amyloid-β plaque load, glial activation, GABAergic interneuron numbers, and cognitive decline in the young TgF344-AD rat model of Alzheimer’s dise... by Anett Futácsi, Anett Futácsi, Anett Futácsi, Kitti Rusznák, Kitti Rusznák, Gergely Szarka, Gergely Szarka, Gergely Szarka, Béla Völgyi, Béla Völgyi, Ove Wiborg, Boldizsár Czéh, Boldizsár Czéh, Boldizsár Czéh

Subjects: “…astrocyte…”
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TDP43 augments astrocyte inflammatory activity through mtDNA-cGAS-STING axis in NMOSD by Zhuhe Liu, Yunmeng Bai, Bingtian Xu, Haixia Wen, Kechun Chen, Jingfang Lin, Yuanyuan Wang, Jiangping Xu, Haitao Wang, Fudong Shi, Jigang Wang, Honghao Wang

“…Single-nucleus RNA sequencing revealed that NMOSD induced A1-like reactive astrocytes and astrocyte mitochondrial dysfunction in mice. …”
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Unveiling the functional connectivity of astrocytic networks with AstroNet, a graph reconstruction algorithm coupled to image processing by L. Zonca, F. C. Bellier, G. Milior, P. Aymard, J. Visser, A. Rancillac, N. Rouach, D. Holcman

“…To address this, we developed AstroNet, a data-driven algorithm that uses two-photon calcium imaging to map temporal correlations in astrocyte activation. By organizing individual astrocyte activation events chronologically, our method reconstructs functional networks and extracts local astrocyte correlations. …”
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Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease: lessons from animal studies by Wouter Claeys, Anja Geerts, Lien Van Hoecke, Christophe Van Steenkiste, Roosmarijn E. Vandenbroucke

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Extracellular Cardiolipin Modulates Select Immune Functions of Astrocytes in Toll-Like Receptor (TLR) 4-Dependent Manner by Taryn E. Murray, Tyler J. Wenzel, Svetlana Simtchouk, Bridget K. Greuel, Julien Gibon, Andis Klegeris

“…We demonstrate that CL inhibits the lipopolysaccharide- (LPS-) induced secretion of cytotoxins and expression of glial fibrillary acidic protein (GFAP) by human U118 MG astrocytic cells. CL alone upregulates the phagocytic activity of human astrocytic cells and primary murine astrocytes. …”
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Withaferin A Inhibits Nuclear Factor-κB-Dependent Pro-Inflammatory and Stress Response Pathways in the Astrocytes by Francesca Martorana, Giulia Guidotti, Liliana Brambilla, Daniela Rossi

“…Several lines of evidence suggest that astrocytes play a key role in modulating the immune responses of the central nervous system (CNS) to infections, injuries, or pathologies. …”
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Retraction Note: Xiaoyaosan exerts antidepressant-like effects by regulating the functions of astrocytes and EAATs in the prefrontal cortex of mice by Yan Liu, Xiu-fang Ding, Xin-xing Wang, Xiao-juan Zou, Xiao-juan Li, Yue-yun Liu, Jie Li, Xiu-yun Qian, Jia-xu Chen

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Multiscale Modeling Indicates That Temperature Dependent [Ca2+]i Spiking in Astrocytes Is Quantitatively Consistent with Modulated SERCA Activity by Niko Komin, Mahsa Moein, Mark H. Ellisman, Alexander Skupin

“…Here we revisit our previously published data on the strong temperature dependence of Ca2+ signals in both cultured primary astrocytes and astrocytes in acute brain slices of mice. …”
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The Absence of Nrf2 Enhances NF-B-Dependent Inflammation following Scratch Injury in Mouse Primary Cultured Astrocytes by Hao Pan, Handong Wang, Xiaoliang Wang, Lin Zhu, Lei Mao

“…Primary cultured astrocytes were scratched to mimic the traumatic injury in vitro. …”
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Pretreatment of Ascorbic Acid Inhibits MPTP-Induced Astrocytic Oxidative Stress through Suppressing NF-κB Signaling by Xiaokang Zeng, Kai Xu, Ji Wang, Yunqi Xu, Shaogang Qu

“…Astrocytes are a major constituent of the central nervous system (CNS). …”
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NaHS modulates astrocytic EAAT2 expression to impact SNI-induced neuropathic pain and depressive-like behaviors by Man-Man Qi, Heng-Yue Peng, Tian-Ge Zhang, Yan Li, Meng-Ya Gao, Wen-Bo Sun, Xu-Peng Wang

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Mechanisms of Cancer-Induced Bone Pain by Wang X, Li L, Wang Y

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The Role of Glial Cells in the Pathophysiology of Epilepsy by Filiz Onat, My Andersson, Nihan Çarçak

Subjects: “…astrocyte…”
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Vincristine Regulates C/EBP-β/TGF-β1 to Promote A1 Astrocyte Polarization and Induce Neuropathic Pain by Chen Y, Tang G, Lu J, Tang S, Xiong X, Chen C, Pei L, Shi J

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Astrocytic HIV-1 Nef Expression Decreases Glutamate Transporter Expression in the Nucleus Accumbens and Increases Cocaine-Seeking Behavior in Rats by Jessalyn Pla-Tenorio, Bethzaly Velazquez-Perez, Yainira Mendez-Borrero, Myrella L. Cruz, Marian T. Sepulveda-Orengo, Richard J. Noel

“…Additionally, rats with astrocytic Nef expression exhibited increased cocaine-seeking behavior but demonstrated sex-dependent molecular differences after the behavioral paradigm. …”
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In Vivo Structural and Functional Abnormalities of the Striatums Is Related to Decreased Astrocytic BDNF in Itpr2-/- Mice Exhibiting Depressive-Like Behavior by Shanmei Zeng, Kai Liu, Jingyu Zhang, Chunhui Chen, Yihua Xu, Yulan Wu, Yanjia Deng, Xuegang Sun, Ge Wen, Linlin Jing

“…By combining biochemistry and MR analyses, this study provides evidences to support that the Itpr2-related neuropathological effect is possibly mediated by the striatal abnormality associated with dysfunctional astrocytes in Itpr2-/- mice in vivo, thus may help us better understand underlying mechanisms of Itpr2 deficiency as well as its relation to depressive-like behavior.…”
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Mechanisms and Emerging Regulators of Neuroinflammation: Exploring New Therapeutic Strategies for Neurological Disorders by Mi Eun Kim, Jun Sik Lee

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Glymphatic system: a self-purification circulation in brain by Siying Chen, Siying Chen, Huijing Wang, Lini Zhang, Yingying Xi, Yiying Lu, Kailin Yu, Yujie Zhu, Izmailova Regina, Yong Bi, Fang Tong, Fang Tong

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Functional abnormalities of the glymphatic system in cognitive disorders by Wuyue Shentu, Qi Kong, Yier Zhang, Wenyao Li, Qiulu Chen, Sicheng Yan, Junjun Wang, Qilun Lai, Qi Xu, Song Qiao

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Effect of Propionic Acid on Diabetes-Induced Impairment of Unfolded Protein Response Signaling and Astrocyte/Microglia Crosstalk in Rat Ventromedial Nucleus of the Hypothalamus by Larysa V. Natrus, Yulia S. Osadchuk, Olha O. Lisakovska, Dmytro O. Labudzinskyi, Yulia G. Klys, Yuri B. Chaikovsky

“…The aim was to investigate the influence of propionic acid (PA) on the endoplasmic reticulum (ER), unfolded protein response (UPR) state, and astrocyte/microglia markers in rat ventromedial hypothalamus (VMH) after type 2 diabetes mellitus (T2DM). …”
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