Down-regulation of SHP2 promotes neutrophil autophagy and inhibits neutrophil extracellular trap formation to alleviate asthma through the ERK5 pathway by Dandan Shi, Jian Huang, Jie Wu

Subjects: “…asthma…”
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Patient-Centric Structural Determinants of Adherence Rates Among Asthma Populations: Exploring the Potential of Patient Activation and Encouragement Tool TRUSTR to Improve Adherence by Asim Zia, Arthur Brassart, Sheila Thomas, Fen Ye, Judith J. Stephenson, C. Daniel Mullins, Christopher A. Jones

“…**Background:** Lack of adherence with prescribed medications among the asthma populations exacerbates health outcomes and increases social and economic costs. …”
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Association between advanced lung cancer inflammation index and all-cause and cause-specific mortality among asthma patients: a cohort study by Tu-Lei Tian, Xiang-Kun Qu, Hong-Bo Zhang, Cun-Cun Wang, Qing-Qing Yuan, Jing Xia, Li-Fang Cao, Kui Liu

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Impact of Low PM2.5 Exposure on Asthma Admission: Age-Specific Differences and Evidence from a Low-Pollution Environment in China by Xiaolong Fan, Chen Yang, Jinsheng Chen, Yuping Chen, Gaojie Chen, Ziyi Lin, Zecong Li, Yanting Chen, Liqian Yin, Lingling Xu, Naian Xiao

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Maternal asthma imprints fetal lung ILC2s via glucocorticoid signaling leading to worsened allergic airway inflammation in murine adult offspring by Tomoaki Takao, Ako Matsui, Chie Kikutake, Keiko Kan-o, Azusa Inoue, Mikita Suyama, Isamu Okamoto, Minako Ito

“…Abstract The root of asthma can be linked to early life, with prenatal environments influencing risk. …”
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House Dust Mite and Cat Dander Extract Induce Asthma-Like Histopathology with an Increase of Mucosal Mast Cells in a Guinea Pig Model by Patricia Ramos-Ramírez, Jielu Liu, Sofia Mogren, Joshua Gregory, Malin Noreby, Anne Petrén, Ying Lei, Henric Olsson, Marianne van Hage, Jukka Kervinen, Lars Hellman, Cecilia Andersson, Gunnar Nilsson, Mikael Adner

“…Background. Asthma is a chronic inflammatory disease with structural changes in the lungs defined as airway remodelling. …”
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Investigation of interleukin-4 (IL-4) and leukotriene C4 synthase (LTC4S) genes in patients with asthma by next-generation sequencing analysis by Muhammet Mesut Nezir Engin, Önder Kılıçaslan, Recep Eröz, Öner Özdemir, Ramazan Temizkan, Kenan Kocabay

Subjects: “…asthma…”
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Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retrospective cohort study by Khalaf Kridin, Khalaf Kridin, Khalaf Kridin, Cristian Papara, Katja Bieber, David A. De Luca, Jan Philipp Klein, Marlene A. Ludwig, Philip Curman, Philip Curman, Philip Curman, Philip Curman, Artem Vorobyev, Astrid Dempfle, Ralf J. Ludwig

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Intensive critical care and management of asthmatic and smoker patients in COVID-19 infection by Lu Dongming, Yaqoob Obaid, Kumar Manish, Kushwah Ajay Singh, Sharma Rahul Kumar, Kumar Devinder, Mavai Yogendra, Khan Rukaiya

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The Importance of Lung Innate Immunity During Health and Disease by Gusty Rizky Teguh Ryanto, Ratoe Suraya, Tatsuya Nagano

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Beyond bronchial thermoplasty – where to now? by Peter B. Noble, David Langton, Chuan T. Foo, Bruce R. Thompson, Alvenia Cairncross, Michael J. Hackmann, Francis Thien, Graham M. Donovan

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Assessing public support for air pollution mitigation and control policies: health, socioeconomic, and ideological predictors in an overburdened and vulnerable region of the U.S. by Gilda Zarate-Gonzalez, Paul Brown, Ricardo Cisneros

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The “real life” efficacy of dupilumab is independent of initial polyp size and concomitant steroids in CRSwNP by Nicholas J. Campion, Jonas Brugger, Aldine Tu, Victoria Stanek, Faris F. Brkic, Tina J. Bartosik, David T. Liu, Bruna S. Hoehl, Katharina Gangl, Julia Eckl-Dorna, Sven Schneider

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A PAF receptor antagonist inhibits acute airway inflammation and late-phase responses but not chronic airway inflammation and hyperresponsiveness in a primate model of asthma by R. H. Gundel, C. D. Wegner, H. O. Heuer, L. G. Letts

“…We have examined the effects of a PAF receptor antagonist, WEB 2170, on several indices of acute and chronic airway inflammation and associated changes in lung function in a primate model of allergic asthma. A single oral administration WEB 2170 provided dose related inhibition of the release of leukotriene C4 (LTC4) and prostaglandin D2 (PGD2) recovered and quantified in bronchoalveolar lavage (BAL) fluid obtained during the acute phase response to inhaled antigen. …”
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Prospective study of factors associated with asthma attack recurrence (ATTACK) in children from three Ecuadorian cities during COVID-19: a study protocol by Cristina Ardura-Garcia, Max Bachmann, Alejandro Rodriguez, Philip Cooper, Michael Richard Perkin, Irina Chis Ster, Natalia Cristina Romero, Martha E Chico, Alvaro Cruz, Diana Morillo, Santiago Mena-Bucheli, Angélica Ochoa, Claudia Rodas, Augusto Maldonado, Karen Arteaga, Jessica Alchundia, Karla Solorzano, Camila Figueiredo

“…Introduction Asthma is a growing health problem in children in marginalised urban settings in low-income and middle-income countries. …”
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Trajectories of asthma symptom presenting as wheezing and their associations with family environmental factors among children in Australia: evidence from a national birth cohort study by Peter D Sly, Md Jobayer Chisti, Abdullah Mamun, K M Shahunja

“…Objectives Asthma is one of the greatest health burdens, yet contributors to asthma symptom trajectories are understudied in Australian children. …”
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IL-13 Augments Histone Demethylase JMJD2B/KDM4B Expression Levels, Activity, and Nuclear Translocation in Airway Fibroblasts in Asthma by Khuloud Bajbouj, Mahmood Y. Hachim, Rakhee K. Ramakrishnan, Huwaida Fazel, Jumana Mustafa, Shahed Alzaghari, Mahmoud Eladl, Jasmin Shafarin, Ronald Olivenstein, Qutayba Hamid

“…Purpose. Asthma is one of the most common obstructive pulmonary diseases worldwide. …”
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IL-8, IL-10, TGF-β, and GCSF Levels Were Increased in Severe Persistent Allergic Asthma Patients with the Anti-IgE Treatment by Arzu D. Yalcin, Atil Bisgin, Reginald M. Gorczynski

“…Background. Allergic asthma is showed an increase in Th2-cytokine and IgE levels and an accumulation activation of Th2 cells, eosinophils and mast cells. …”
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The role of polymorphic variants of arginase genes (<i>ARG1, ARG2</i>) involved in beta-2-agonist metabolism in the development and course of asthma by O. N. Savelieva, A. S. Karunas, Yu. Yu. Fedorova, R. R. Murzina, A. N. Savelieva, R. F. Gatiyatullin, E. I. Etkina, E. K. Khusnutdinova

Subjects: “…asthma…”
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Asthma and Allergic Disease Prevalence in a Diverse Sample of Toronto School Children: Results from the Toronto Child Health Evaluation Questionnaire (T-CHEQ) Study by Sharon D Dell, Richard G Foty, Nicolas L Gilbert, Michael Jerrett, Teresa To, Stephen D Walter, David M Stieb

“…BACKGROUND: Asthma is the most common chronic disease in children.…”
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