MBD2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting IRF4 Expression by Aijun Jia, Yueling Wang, Wenjin Sun, Bing Xiao, Yan Wei, Lulu Qiu, Lin Mu, Li Xu, Jianmin Li, Xiufeng Zhang, Da Liu, Cong Peng, Dongshan Zhang, Xudong Xiang

“…Th17 cells and IL-17 participate in airway neutrophil infiltration characteristics in the pathogenesis of severe asthma. Methyl-CpG binding domain protein 2 (MBD2) expression increased in CD4+ T cells in peripheral blood samples of asthma patients. …”
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Association between air pollutants and blood cell counts in pediatric patients with asthma: a retrospective observational study by Kuo-Chen Huang, Hsiu-Yung Pan, Ting-Min Hsieh, Chih-Cheng Chen, Fu-Jen Cheng

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Major Care Gaps in Asthma, Sleep and Chronic Obstructive Pulmonary Disease: A Road Map for Knowledge Translation by Louis-Philippe Boulet, Jean Bourbeau, Robert Skomro, Samir Gupta

“…Using the ‘Knowledge-to-Action Framework’, the nature of each gap, its magnitude, the barriers that cause and perpetuate it, and past and future strategies that might address the problem were considered. In asthma: disease control is ascertained inadequately, leading to a prevalence of poor asthma control of approximately 50%; and asthma action plans, a key component of asthma management, are provided by only 22% of physicians. …”
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Analysis of the incidence of asthma among pupils of primary schools in Bielsko-Biala located in areas with various degrees of industrialization by Dariusz Jerzy Góra, Jerzy Kupiec

Subjects: “…asthma…”
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Perinatal Cat and Dog Exposure and the Risk of Asthma and Allergy in the Urban Environment: A Systematic Review of Longitudinal Studies by Caroline J. Lodge, Katrina J. Allen, Adrian J. Lowe, David J. Hill, Cliff S. Hosking, Michael J. Abramson, Shyamali C. Dharmage

“…The literature is contradictory concerning pet exposure and the risk of development of asthma and other allergic diseases. Using longitudinal studies, we aimed to systematically review the impact of pet ownership in the critical perinatal period as a risk factor for allergies in childhood. …”
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The Association between Birth Weight and Gestational Age and Asthma in 6-7- and 13-14-Year-Old Children by Zamani Raheleh, Alikhani Ahmad, Heydarzadeh Abtin, Zare Roghaye, Hashemain Sara, Rahimi Siavash

“…Previous studies that assessed the role of birth weight and gestational age in the risk of asthma have been conflicting. Objectives. To examine the association between birth weight and gestational age and symptoms of asthma. …”
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Healthcare utilisation by pregnant patients with asthma in South Korea: a cohort study using nationwide claims data by Deog Kyeom Kim, Chang-Hoon Lee, Ho Il Yoon, Jae-Joon Yim, Eun Jin Jang, Jimin Kim, Yun Jung Kim, Seongmi Choi, Joon-Ho Lee

“…Objectives Few nationwide population-based studies have examined the burden of asthma during pregnancy. Here, we investigated the burden and medical treatment of asthma during pregnancy requiring healthcare utilisation in South Korea.Design Cohort study.Setting Nationwide insurance claims database.Participants A total of 1 306 281 pregnant women who delivered in South Korea in 2009–2011.Outcomes The prevalence and exacerbation rates of asthma requiring healthcare utilisation, and the prescription of antiasthmatic drugs during pregnancy.Results The prevalence of asthma requiring healthcare utilisation was 0.43% among pregnant women. …”
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Eosinophilic Asthma Secondary to Adjuvant Anti-PD-1 Immune Checkpoint Inhibitor Treatment in a Melanoma Patient by P. Kissoonsingh, B. Sutton, Syed U. Iqbal, Lalit Pallan, Neil Steven, L. Khoja

“…We report, to our knowledge, the first case of anti-PD-1-induced eosinophilic asthma in a melanoma patient treated with adjuvant pembrolizumab. …”
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PARP-1 Is Critical for Recruitment of Dendritic Cells to the Lung in a Mouse Model of Asthma but Dispensable for Their Differentiation and Function by Laura C. Echeverri Tirado, Mohamed A. Ghonim, Jeffrey Wang, Amir A. Al-Khami, Dorota Wyczechowska, Hanh H. Luu, Hogyoung Kim, Maria Dulfary Sanchez-Pino, José Yélamos, Lina M. Yassin, A. Hamid Boulares

“…Dendritic cells (DCs) are critical in asthma and many other immune diseases. We previously demonstrated a role for PARP-1 in asthma. …”
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Canadian Adult Asthma Update 2008 Key Messages: A Focus on Translating Knowledge into Action in Primary Care by Andrew McIvor, Rick Hodder

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The Joint Association of Sleep Quality and Outdoor Activity with Asthma and Allergic Rhinitis in Children: A Cross-Sectional Study in Shanghai by Lu R, Zhang Y, Chen Y, Lyu J, Li R, Kang W, Zhao A, Ning Z, Hu Y, Lin X, Tong S, Lu Z, Li S

Subjects: “…asthma…”
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Penggunaan Asthma Control Test (ACT) secara Mandiri oleh Pasien untuk Mendeteksi Perubahan Tingkat Kontrol Asmanya by Yessy Susanty Sabri, Yusrizal Chan

“…The purpose of this study was to determine the effectiveness of the use of ACT independently by asthma patients to detect changes in the level of asthma control. …”
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A Case of Severe Asthma with Eosinophilic Otitis Media Successfully Treated with Anti-IgE Monoclonal Antibody Omalizumab by Azusa Okude, Etsuko Tagaya, Mitsuko Kondo, Manabu Nonaka, Jun Tamaoki

“…A 51-year-old woman had been receiving medical treatment for asthma since she was 21 years old. However, her asthma was poorly controlled despite treatment involving combination inhalation of high-dose corticosteroid and long-acting β2-aderenergic agonist (LABA) and regularly taking oral steroids. …”
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Hyssopus cuspidatus volatile oil: a potential treatment for steroid-resistant asthma via inhibition of neutrophil extracellular traps by Xu Wang, Hui-Ming Peng, Meng-Ru Zhang, Jing-Jing Li, Chuan-Peng Zhao, Ya-Li Zhang, Si-Yu Wang, Si-Ying Zhu, Jian-Kang Lu, Hai-Long Yin, Qiang Yin, Jin-Bo Fang

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High-Flow Nasal Cannula: A Promising Oxygen Therapy for Patients with Severe Bronchial Asthma Complicated with Respiratory Failure by Wanru Geng, Wuliji Batu, Shuhong You, Zhaohui Tong, Hangyong He

“…Severe bronchial asthma complicated with respiratory failure, a common critical illness in respiratory medicine, may be life-threatening. …”
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Inflammatory Mediators in Induced Sputum and Airway Hyperresponsiveness in Cough Variant Asthma during Long-Term Inhaled Corticosteroid Treatment by Meixuan Liu, Kaixiong Liu, Ning Zhu, Jingwen Xia, Xiaodong Chen

“…Patients with CVA (𝑁=35) and classic asthma (𝑁=26) and healthy subjects (𝑁=24) were recruited into this study. …”
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γ-Secretase Inhibitor Alleviates Acute Airway Inflammation of Allergic Asthma in Mice by Downregulating Th17 Cell Differentiation by Weixi Zhang, Xueya Zhang, Anqun Sheng, Cuiye Weng, Tingting Zhu, Wei Zhao, Changchong Li

“…T helper 17 (Th17) cells play an important role in the pathogenesis of allergic asthma. Th17 cell differentiation requires Notch signaling. γ-Secretase inhibitor (GSI) blocks Notch signaling; thus, it may be considered as a potential treatment for allergic asthma. …”
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Association between dietary carotenoid intakes and the risk of asthma in adults: a cross-sectional study of NHANES, 2007–2012 by Weijie Li, Wei Zhang, Jie Du

“…Objective To investigate the association between dietary carotenoid intake and asthma using data from a nationally representative sample of US adults.Design Cross-section study.Setting The National Health and Nutrition Examination Survey 2007–2012.Participants A total of 13 039 participants aged 20–80 years (current asthma n=1784, non-current asthma n=11 255) were included in this study.Primary and secondary outcome measures Asthma was defined by self-report questionnaires. …”
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Adherence to Pediatric Asthma Guidelines in the Emergency Department: A Survey of Knowledge, Attitudes and Behaviour among Health Care Professionals by Sanjit K Bhogal, Jean Bourbeau, David McGillivray, Andrea Benedetti, Susan J Bartlett, Francine M Ducharme

“…BACKGROUND: Despite strong evidence for using clinical care pathways to manage acute pediatric asthma, adherence remains suboptimal.…”
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Adipose-Derived Stem Cells Ameliorate Allergic Airway Inflammation by Inducing Regulatory T Cells in a Mouse Model of Asthma by Kyu-Sup Cho, Mi-Kyung Park, Shin-Ae Kang, Hee-Young Park, Sung-Lyong Hong, Hye-Kyung Park, Hak-Sun Yu, Hwan-Jung Roh

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