Association of CYP2C9∗3 and CYP2C8∗3 Non-Functional Alleles with Ibuprofen-Induced Upper Gastrointestinal Toxicity in a Saudi Patient by Amina M. Bagher

“…We presented a case of a 31-year-old Saudi female patient with a history of rheumatoid arthritis (RA) who had taken ibuprofen at 600 mg twice daily for eight weeks. …”
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Analgesic Mechanism of Sinomenine against Chronic Pain by Wei Jiang, Weiming Fan, Tianle Gao, Tao Li, Zhenming Yin, Huihui Guo, Lulu Wang, Yanxing Han, Jian-Dong Jiang

“…Purified from the roots of the plant Sinomenium acutum, sinomenine is traditionally used in China and Japan for treating rheumatism and arthritis. Previously, we have demonstrated that sinomenine possessed a broad analgesic spectrum in various chronic pain animal models and repeated administration of sinomenine did not generate tolerance. …”
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CpG Oligodeoxynucleotides Inhibit RANKL-Induced Osteoclast Formation by Upregulating A20 Deubiquitinase in RAW 264.7 Cells by Seong-Kyu Kim, Jung-Yoon Choe, Ki-Yeun Park

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Epstein-Barr Virus- (EBV-) Immortalized Lymphoblastoid Cell Lines (LCLs) Express High Level of CD23 but Low CD27 to Support Their Growth by Hooi-Yeen Yap, Thin-Sam Siow, Sook-Khuan Chow, Sin-Yeang Teow

“…This study demonstrates the generation of 15 LCLs from sixteen rheumatoid arthritis (RA) patients and a healthy volunteer using B95-8 marmoset-derived EBV. …”
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Natural Killer T (NKT) Cells and Periodontitis: Potential Regulatory Role of NKT10 Cells by Samanta Melgar-Rodríguez, Emilio A. Cafferata, Nicolás I. Díaz, Miguel A. Peña, Luis González-Osuna, Carolina Rojas, Alfredo Sierra-Cristancho, Angélica M. Cárdenas, Jaime Díaz-Zúñiga, Rolando Vernal

“…Although the tissue-specific functions of NKT cells have not been fully elucidated, their activity has been associated with the pathogenesis of different inflammatory diseases with immunopathogenic similarities to periodontitis, including osteolytic pathologies such as rheumatoid arthritis and osteoporosis. In the present review, we revise and discuss the pathogenic characteristics of NKT cells in these diseases and their role in the pathogenesis of periodontitis; particularly, we analyze the potential regulatory role of the IL-10-producing NKT10 cells.…”
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The Role of Additional K-Wires on AO Type C Distal Radius Fracture Treatment with External Fixator in Young Population by Ivan Micic, Erica Kholinne, Yucheng Sun, Jae-Man Kwak, In-Ho Jeon

“…Radiologic outcome parameters include radial inclination, volar tilt, radial length, and the presence of radiocarpal arthritis according to Knirk and Jupiter. Clinical outcomes include New York Orthopedic Hospital (NYOH) wrist scoring scale. …”
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Osteoarthritis synovium as a nidus for monosodium urate crystal deposition inducing severe gout studied by label‐free stimulated Raman scattering combined with synovial organoids by Ziyi Chen, Wenjuan Wang, Yaxin Chen, Minbiao Ji, Yinghui Hua

“…Osteoarthritis (OA), the most prevalent type of arthritis, is a progressive degenerative joint disease. …”
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Severe Disfiguring Scalp and Facial Oedema due to Henoch–Schönlein Purpura in a Child by Visvalingam Arunath, Arjuna Salinda Athapathu, Thabitha Jebaseeli Hoole, Heshan Aruppala, Asanka Rathnasri, Randula Ranawaka, Sachith Mettananda

“…Henoch–Schönlein purpura is a small vessel vasculitis that usually presents with palpable purpura, arthritis, abdominal pain, and nephritis. Subcutaneous oedema of dependent areas is common; however, oedema in the scalp is extremely rare especially in children older than two years. …”
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Collapsing glomerulopathy associated with parvovirus B19 and systemic lupus erythematosus in a patient with APOL1 high-risk variant for nephropathy by Thaíza Passaglia Bernardes, Thalita Alvarenga Ferradosa Paula, Gabriel Teixeira Montezuma Sales, Patrícia Varela Calais, Renato Demarchi Foresto, Luiz Antonio Moura, Marcelino de Souza Durão Junior, João Bosco Pesquero, Gianna Mastroianni Kirsztajn

“…A 35-year-old woman with recent use of a JAK inhibitor due to rheumatoid arthritis presented with a 2-week history of fever, cervical adenopathy, and facial erythema. …”
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Conducting genetic epidemiology research on hyperuricaemia and gout in an indigenous community in Guam - a feasibility study by Yvette C. Paulino, Frank Camacho, Tristan VC Paulino, Delores J. Lee, Lisa Linda Natividad, Elizabeth Matisoo-Smith, Tony R. Merriman, Anna L. Gosling

“…Abstract Background Gout, the most common inflammatory arthritis disease, and hyperuricaemia onset are influenced by environmental and genetic factors. …”
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Clinical Evidence and Risk Factors for Reproductive Disorders Caused by Bacterial Infections in Meat Goats in Northeastern Thailand by Sarinya Rerkyusuke, Sawarin Lerk-u-suke, Anucha Sirimalaisuwan

“…A total of 118 sera, including 85 clinical reproductive disorder cases such as abortion (n = 70), abortion with arthritis (n = 1), orchitis (n = 3), repeat breeder (n = 6), sterile (n = 1), and weak kids (n = 4), and 33 bucks’ circulations were serologically tested for bacterial infections caused by Coxiella burnetii, Chlamydophila abortus, and Brucella spp. …”
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Chloroplast genome characteristics and phylogenetic analysis of Macropanax rosthornii (Harms) C.Y. Wu ex G. Hoo (Araliaceae) by Shuxin Du, Huiying Huang, Shuhui Yang, Tianyi Gu, Mengli Zhou, Ruihong Wang

“…M. rosthornii is a kind of high-quality wild ornamental plant resource and is also known for its effective medicinal treatment for fracture, rheumatoid arthritis, traumatic injury, infant malnutrition, etc. …”
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In situ forming gels as subcutaneous delivery systems of curcumin and piperine by Walter Pula, Alessia Pepe, Francesca Ferrara, Agnese Bondi, Paolo Mariani, Maria Grazia Ortore, Alessandra Pecorelli, John Ivarsson, Giuseppe Valacchi, Elisabetta Esposito

“…Abstract In this study an in situ forming gel for curcumin and piperine delivery is investigated as a long-lasting strategy in the local treatment of inflammatory and degenerative joint disease, such as osteoarthritis and rheumatoid arthritis. Particularly glyceryl monooleate, in association with phosphatidylcholine and ethanol, were employed. …”
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Prevalence of Fracture Risk Factors in Postmenopausal Women Enrolled in the POSSIBLE US Treatment Cohort by Nicole Yurgin, Sally Wade, Sacha Satram-Hoang, David Macarios, Marc Hochberg

“…RFs assessed at study entry were age >70 years; fracture since age 50; minimum T-score (hip/spine) ≤−2.5 at diagnosis; body mass index <18.5 kg/m2; rheumatoid arthritis; parental history of hip fracture; current smoking; and recent oral glucocorticoid use. …”
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Evaluation of the strategy for implementing the GLA:D programme in Switzerland: protocol for an implementation-effectiveness hybrid type 3 design study with a mixed-method approach by Karin Niedermann, Lea Ettlin, Marina Bruderer-Hofstetter, Anne-Kathrin Rausch-Osthoff, Irina Nast, Olivier Gaugler

“…After an analysis of available programmes, the Good Life with osteoArthritis Denmark (GLA:D) programme was determined as the most applicable exercise and education programme for its implementation in Switzerland. …”
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Intravenous immunoglobulin in the management of idiopathic inflammatory myositis: A single centre retrospective review by Jeet Hemantkumar Patel, Lalit Duggal, Ved Chaturvedi, Neeraj Jain, Gurbir Bhandari, Mayank Gupta

“…IVIG-treated patients had a more extended hospital stay and less arthritis (P < 0.05). A common indication of IVIG use was esophageal ± respiratory muscle weakness (n = 5/10). …”
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Patients' perceived needs of osteoarthritis health information: A systematic scoping review. by Louisa Chou, Lisa Ellis, Michelle Papandony, K L Maheeka D Seneviwickrama, Flavia M Cicuttini, Kaye Sullivan, Andrew J Teichtahl, Yuanyuan Wang, Andrew M Briggs, Anita E Wluka

“…Patients wanted clear explanations. (2) Need for information from various sources: patients wanted accessible health professionals with specialist knowledge of arthritis. The Internet, whilst a source of information, was acknowledged to have dubious reliability. …”
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Common Variable Immunodeficiency Associated with Hepatosplenic T-Cell Lymphoma Mimicking Juvenile Systemic Lupus Erythematosus by A. A. Jesus, C. M. A. Jacob, C. A. Silva, M. Dorna, A. C. Pastorino, M. Carneiro-Sampaio

“…At the age of 17 years, she presented with oral ulceration, nonerosive arthritis, nephritis, serositis, cytopenia, positive antiphospholipid antibodies, and positive antinuclear antibody fulfilling the American College of Rheumatology (ACR) criteria for SLE. …”
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Infectious and Noninfectious Acute Pericarditis in Children: An 11-Year Experience by Nahed Abdel-Haq, Zeinab Moussa, Mohamed Hani Farhat, Leela Chandrasekar, Basim I. Asmar

“…Pericarditis/pericardial effusion was the initial presentation in 4 children with systemic lupus erythematosus including one who presented with tamponade and in 2 children who were diagnosed with systemic onset juvenile inflammatory arthritis. Tumors were diagnosed in 2 patients. Five children had recurrent pericarditis. …”
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Exploring the Therapeutic Landscape: A Narrative Review on Topical and Oral Phosphodiesterase-4 Inhibitors in Dermatology by Elena Carmona-Rocha, Lluís Rusiñol, Lluís Puig

“…Apremilast was the first PDE4 inhibitor approved by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for psoriasis, psoriatic arthritis, and oral ulcers of Behcet’s disease. Off-label use has been reported in diverse dermatological conditions, including aphthous stomatitis, chronic actinic dermatitis, atopic dermatitis, cutaneous sarcoidosis, hidradenitis suppurativa, lichen planus, and discoid lupus erythematosus. …”
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