The prevalence and evidence-based management of needle fear in adults with chronic disease: A scoping review. by Emily Duncanson, Richard K Le Leu, Lisa Shanahan, Luke Macauley, Paul N Bennett, Rick Weichula, Stephen McDonald, Anne L J Burke, Kathryn L Collins, Anna Chur-Hansen, Shilpanjali Jesudason

“…The following chronic diseases were included: arthritis, asthma, chronic back pain, cancer, cardiovascular disease, chronic obstructive pulmonary disease, diabetes, and mental illness, or kidney failure. …”
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Iguratimod prevents renal fibrosis in unilateral ureteral obstruction model mice by suppressing M2 macrophage infiltration and macrophage–myofibroblast transition by Yueyuan Zhou, Zhilan Li, Shenyi Yu, Xuan Wang, Tingting Xie, Weiru Zhang

“…Iguratimod is a novel synthetic, small-molecule immunosuppressive agent used to treat rheumatoid arthritis. Through ongoing exploration of its role and mechanisms of action, iguratimod has been observed to have antifibrotic effects in the lung and skin; however, its effect on renal fibrosis remains unknown. …”
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The Causal Relationship between Immune-Mediated Inflammatory Diseases and Aortic Aneurysm: A Bidirectional Two-Sample Mendelian Randomization Study by Sijia Sun, Jie Li, Mengxian Sun, Jie He, Songtao Tan, Ge Wang, Yuan Zheng, Xiaoping Fan

“…The causal estimates obtained using the IVW method revealed a significant association between genetically predicted AA and rheumatoid arthritis (RA; OR = 1.06, 95% CI = 1.01–1.12, P=0.029). …”
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Outcomes of Open Knee Joint Injuries in Trauma Patients at Tibebe-Ghion Specialized Hospital, Bahir-Dar, Ethiopia by Getachew Wuhib Shumye, Melatwork Assefa Wolle, Mekuriaw Wuhib Shumye, Leul Mekonnen Zeru

“…Among the diagnosed infections, 90% were cases of septic arthritis. During the study period, eight patients (18.6%) developed limping during follow-up. …”
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Methotrexate Induced Pancytopenia by Fernando Gonzalez-Ibarra, Sahar Eivaz-Mohammadi, Shiri Surapaneni, Hazem Alsaadi, Amer K. Syed, Simon Badin, Valentin Marian, Mazhar Elamir

“…We present a case of a 73-year-old female with pancytopenia causing severe neutropenia, mucocutaneous bleeding, and bruising and requiring intravenous antibiotic therapy and limited transfusion dependence as a result of low dose daily MTX for rheumatoid arthritis.…”
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The Protective Role of HLA-DRB113 in Autoimmune Diseases by Andreia Bettencourt, Cláudia Carvalho, Bárbara Leal, Sandra Brás, Dina Lopes, Ana Martins da Silva, Ernestina Santos, Tiago Torres, Isabel Almeida, Fátima Farinha, Paulo Barbosa, António Marinho, Manuela Selores, João Correia, Carlos Vasconcelos, Paulo P. Costa, Berta Martins da Silva

“…We genotyped for HLA-DRB1 locus 1228 patients with AIDs-213 with Systemic Lupus Erythematosus (SLE), 166 with Psoriasis or Psoriatic Arthritis (Ps + PsA), 153 with Rheumatoid Arthritis (RA), 67 with Systemic Sclerosis (SSc), 536 with Multiple Sclerosis (MS), and 93 with Myasthenia Gravis (MG) and 282 unrelated controls. …”
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Isolation, Characterization, and Molecular Modeling of a Rheumatoid Factor from a Hepatitis C Virus Infected Patient with Sjögren’s Syndrome by Yu-Ching Lee, Keng-Chang Tsai, Sy-Jye Leu, Tuan-Jen Wang, Chia-Yu Liu, Yi-Yuan Yang

“…We have previously isolated several IgG rheumatoid factors (RFs) from patients with both rheumatoid arthritis and idiopathic thrombocytopenia purpura using phage display system. …”
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Antipleuritic and Vascular Permeability Inhibition of the Ethyl Acetate-Petroleum Ether Stem Bark Extract of Maerua angolensis DC (Capparaceae) in Murine by Felix Agyei Ampadu, Eric Boakye-Gyasi, Newman Osafo, Charles Kwaku Benneh, Edmund Ekuadzi, Eric Woode

“…Maerua angolensis has been used traditionally in the management of pain, arthritis, and rheumatism in Ghana and Nigeria but no scientific evidence is currently available to give credence to its folkloric use. …”
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Interleukin-1 as a Common Denominator from Autoinflammatory to Autoimmune Disorders: Premises, Perils, and Perspectives by Giuseppe Lopalco, Luca Cantarini, Antonio Vitale, Florenzo Iannone, Maria Grazia Anelli, Laura Andreozzi, Giovanni Lapadula, Mauro Galeazzi, Donato Rigante

“…An overview of monogenic autoinflammatory disorders, PFAPA syndrome, rheumatoid arthritis, type 2 diabetes mellitus, uveitis, pericarditis, Behçet’s disease, gout, Sjögren’s syndrome, interstitial lung diseases, and Still’s disease is presented to highlight the fundamental points that interleukin-1 displays in the cryptic interplay between innate and adaptive immune systems.…”
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A3 Adenosine Receptor Allosteric Modulator Induces an Anti-Inflammatory Effect: In Vivo Studies and Molecular Mechanism of Action by Shira Cohen, Faina Barer, Sara Bar-Yehuda, Adriaan P. IJzerman, Kenneth A. Jacobson, Pnina Fishman

“…LUF6000 administration induced anti-inflammatory effect in 3 experimental animal models of rat adjuvant induced arthritis, monoiodoacetate induced osteoarthritis, and concanavalin A induced liver inflammation in mice. …”
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The Inhibitory Effect of Alisol A 24-Acetate from Alisma canaliculatum on Osteoclastogenesis by Kwang-Jin Kim, Alain Simplice Leutou, Jeong-Tae Yeon, Sik-Won Choi, Seong Hwan Kim, Sung-Tae Yee, Kyung Hee Choi, Sang-Jip Nam, Young-Jin Son

“…Osteoclasts are bone-resorbing multinucleated cells, and overactive osteoclasts and/or their increased number are observed in bone disorders including osteoporosis and rheumatoid arthritis. Bioactivity-guided fractionations led to the isolation of alisol A 24-acetate from the dried tuber of Alisma canaliculatum. …”
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Brain Abscess and Keratoacanthoma Suggestive of Hyper IgE Syndrome by Soheyla Alyasin, Reza Amin, Alireza Teymoori, Hamidreza Houshmand, Gholamreza Houshmand, Mohammad Bahadoram

“…At the age of 4 years, he developed a seronegative polyarticular arthritis. Another skin biopsy was taken which was in favor of Keratoacanthoma. …”
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The association of lipids and novel non-statin lipid-lowering drug target with osteoporosis: evidence from genetic correlations and Mendelian randomization by Qingcong Zheng, Rongjie Lin, Du Wang, Rongsheng Chen, Weihong Xu

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Understanding Cardiovascular Events With JAK Inhibitors: Tofacitinib Reduces Synovial and Vascular Inflammation but not the Prothrombotic Effects of Inflammatory Cytokines on Endot... by Aliki Zavoriti, Pierre Miossec

“…Objective Inflammation drives cardiovascular disease in rheumatoid arthritis (RA). Treatment with tofacitinib, a JAK1/JAK3 inhibitor, is associated with increased cardiovascular events in patients with RA. …”
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Association Between Depressive Symptoms and Comorbidities Among Elderly Diabetic Individuals in China by Luyao Qiao, Xin Pan, Tianpei Li, Shouqin Yi, Zhenyu Tang

“…With the exception for dyslipidemia (OR = 1.195, 95% CI: 0.969, 1.475), individuals with hypertension, heart disease, stroke, kidney disease, memory‐related disease, or arthritis/rheumatism were prone to develop depressive status in the fully adjusted model. …”
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What Is the Prevalence of Hip Abductor Pathology in Patients Undergoing Total Hip Arthroplasty? by David A. Brethouwer, DO, Matthew L. Brown, MD, Julie C. McCauley, MPH, William D. Bugbee, MD, Eric Y. Chang, MD, Alecio F. Lombardi, MD, Brian J. Rebolledo, MD

“…Background: Total hip arthroplasty (THA) is generally considered a successful operation for patients with advanced hip arthritis. Hip abductor pathology can lead to diminished outcomes. …”
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Matrix Metalloproteinases: Inflammatory Regulators of Cell Behaviors in Vascular Formation and Remodeling by Qishan Chen, Min Jin, Feng Yang, Jianhua Zhu, Qingzhong Xiao, Li Zhang

“…Abnormal angiogenesis and vascular remodeling contribute to pathogenesis of a number of disorders such as tumor, arthritis, atherosclerosis, restenosis, hypertension, and neurodegeneration. …”
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MicroRNA-155 Participates in the Expression of LSD1 and Proinflammatory Cytokines in Rheumatoid Synovial Cells by Ziliang Yu, Hao Liu, Jianbo Fan, Feihu Chen, Wei Liu

“…MicroRNA-155 (miRNA-155) is abundant in fibroblast-like synoviocytes (FLS) in rheumatoid arthritis (RA). Lysine-specific demethylase 1 (LSD1) has been found that it can ameliorate the severity of RA. …”
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Risk versus Benefit of Using Hydroxychloroquine to Treat Patients with COVID-19 by George G. Zhanel, Michael A. Zhanel, Kevin F. Boreskie, Joseph P. Lynch, James A. Karlowsky

“…Hydroxychloroquine (HCQ), also known by its trade name Plaquenil®, has been used for over 50 years as a treatment for malaria, systemic lupus erythematosus, and rheumatoid arthritis. As the COVID-19 pandemic emerged in the United States and globally in early 2020, HCQ began to garner attention as a potential treatment and as prophylaxis against COVID-19. …”
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Association Between MRI Findings of Facet Arthropathy and Synovitis With Health-Related Outcome and Pain Scores Following Therapeutic Lumbar Facet Injections by Michael S. Green, Michele Van Hal, Matthew Onimus, Christopher R. Hoffman, Dhruv K. C. Goyal, Valeria Potigailo, Khuram S. Kazmi

“…Although its underlying etiology remains poorly understood, recent reports suggest a high incidence in patients with arthropathy and arthritis. It is essential to explore potential correlations between specific MRI findings and outcomes after lumbar facet injections. …”
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