Granulomatous Hepatitis Secondary to Histoplasma Infection after Treatment with Infliximab by L. Barrera, J. Álvarez, M. Tapias, V. Idrovo, R. López

“…We present a case of a female patient with rheumatoid arthritis who received treatment with Infliximab during one and a half year; she developed granulomatous hepatitis secondary to Histoplasma infection. …”
Get full text

Repository Corticotropin Injection for Treatment of Idiopathic Inflammatory Myopathies by Aarat Patel, Georgia Seely, Rohit Aggarwal

Get full text

Leflunomide induced drug reaction with eosinophilia and systemic symptoms: A lesser known entity by Deepak Vashisht, Madhab Durga Tripathy, Sunmeet Sandhu, Rohit Kothari, Surbhi Vashisht, Arun Hegde

“…A 56-year-old lady, a known case of rheumatoid arthritis on treatment, developed diffuse exanthematous rash over body with fever and hepatic dysfunction, a month after administration of leflunomide. …”
Get full text

Effectiveness and Safety of Infliximab in Two Cases of Severe Chondrocalcinosis: Nine Years of Follow-Up by Jácome Bruges-Armas, Bruno F. Bettencourt, Ana R. Couto, Manuela Lima, Ana M. Rodrigues, Nathan Vastesaeger, Matthew A. Brown

Get full text

Suppression of Carrageenan- and Collagen II-Induced Inflammation in Mice by Geranium Oil by Naho Maruyama, Hiroko Ishibashi, Weimin Hu, Shinichiro Morofuji, Shigeharu Inouye, Hideyo Yamaguchi, Shigeru Abe

“…Single intraperitoneal injection of 5 μL of geranium oil clearly suppressed the carrageenan-induced footpaw edema and increase in tissue myeloperoxidase activity, and repeated administration of the oil suppressed collagen-induced arthritis. These results revealed that geranium oil suppressed both acute and chronic inflammatory responses in mice.…”
Get full text

A Rare and Intriguing Case of Wilson's Disease Initially Suspected of Systemic Lupus Erythematosus by Mandana Khodashahi, Najmeh Mohajeri, Moeid Reza Alipour, Reza Khademi, Nama Mohamadian Roshan, Behzad Aminzadeh, Muhammed Joghatayi

“…., positive anti‐double‐stranded DNA antibody, low complement component 3) are inconsistent with physical findings, such as the absence of arthritis or nephritis, clinicians should consider diagnoses such as Wilson's disease, especially in the presence of abnormal liver function and elevated international normalized ratio (INR).…”
Get full text

Suprascapular Nerve Pulsed Radiofrequency for Chronic Shoulder Pain in a Pediatric Patient by Federico Cristiani, Maria A. Hernandez

“…We present a 53 kg, 14-year-old female, with a medical history of septic arthritis of the left shoulder within the first month of life leading to persisting pain during childhood. …”
Get full text

Clinical Insights into Tubercular Tenosynovitis: A Series of Eight Compound Palmar Ganglion Cases by Esa Gokulakrishnan, Prem K Kothimbakkam, Bharath Vadivelkumar, Vijayashankar Murugesan

“…Chronic flexor tenosynovitis of the wrist is often associated with tuberculosis in developing countries as opposed to rheumatoid arthritis in developed countries. A case series of compound palmar ganglion (eight cases) mimicking flexor tenosynovitis, for which magnetic resonance imaging (MRI) revealed conclusive evidence of cystic swelling and melon seed bodies. …”
Get full text

Multicentric Castleman's Disease in a Hepatitis C-Positive Intravenous Drug User: A Case Report by D. Y. Talukder, S. N. Delpachitra

“…Osteomyelitis of vertebrae T8–T11 and septic arthritis of the knee were found on investigation. …”
Get full text

Th17 Cells in Immunity and Autoimmunity by Simone Kennedy Bedoya, Brandon Lam, Kenneth Lau, Joseph Larkin

“…However, strong evidence also implicates the Th17 lineage in several autoimmune disorders including multiple sclerosis, psoriasis, rheumatoid arthritis, inflammatory bowel disease, systemic lupus erythematosus, and asthma. …”
Get full text

A Case Report on Chikungunya Virus-Associated Encephalomyelitis by Harsh Khatri, Heli Shah, Dhara Roy, Kaushalendra Mani Tripathi

“…Chikungunya is a dengue-like illness characterized by acute febrile polyarthralgia, arthritis, malaise, body ache, rash, headache, and nausea. …”
Get full text

New-Onset Panic, Depression with Suicidal Thoughts, and Somatic Symptoms in a Patient with a History of Lyme Disease by Amir Garakani, Andrew G. Mitton

“…Lyme Disease, or Lyme Borreliosis, caused by Borrelia burgdorferi and spread by ticks, is mainly known to cause arthritis and neurological disorders but can also cause psychiatric symptoms such as depression and anxiety. …”
Get full text

Role of Interleukin- (IL-) 17 in the Pathogenesis and Targeted Therapies in Spondyloarthropathies by I-Tsu Chyuan, Ji-Yih Chen

“…Previous genetic association studies have demonstrated that several cytokine pathways play a critical role in the pathogenesis of ankylosing spondylitis (AS), psoriatic arthritis (PsA), and other types of SpA. In addition to several well-known proinflammatory cytokines, recent studies suggest that IL-17 plays a pivotal role in the pathogenesis of SpA. …”
Get full text

Ferritin in Adult-Onset Still’s Disease: Just a Useful Innocent Bystander? by Bella Mehta, Petros Efthimiou

“…Adult-Onset Still’s Disease (AOSD) is an immune-mediated systemic disease with quotidian-spiking fever, rash, and inflammatory arthritis. Hyperferritinemia is a prominent feature, often used for screening. …”
Get full text

Leprosy with Atypical Skin Lesions Masquerading as Relapsing Polychondritis by Punit Pruthi, Hariharan Munganda, Amit Bangia, Uma Rani, Rajesh Budhiraja, Swapnil Brajpuriya

“…After dermatological and neurological involvement, rheumatic features specially various forms of arthritis are the third most common manifestation of the disease. …”
Get full text

Ignoring Gender-Based Immunometabolic Reprograming, a Risky Business in Immune-Based Precision Medicine by Vijay Kumar

“…However, further research has indicated sex/gender-based immune differences, which further increase higher incidences of various autoimmune diseases (AIDs), such as systemic lupus erythematosus (SLE), myasthenia gravis, and rheumatoid arthritis (RA) in females. On the other hand, reproductive-age females also show a more potent immune response against infections and vaccines than their age-matched males—furthermore, some immune-based therapies, including immune checkpoint inhibitors (ICIs), show gender-based efficacy and adverse events. …”
Get full text

JC Virus PCR Detection Is Not Infallible: A Fulminant Case of Progressive Multifocal Leukoencephalopathy with False-Negative Cerebrospinal Fluid Studies despite Progressive Clinica... by Mohamed-Ali Babi, William Pendlebury, Steven Braff, Waqar Waheed

“…We describe a case with a false-negative PCR-based analysis for JC virus in cerebrospinal fluid (CSF) in a patient with clinical and radiological findings suggestive of progressive multifocal leukoencephalopathy (PML) who was on chronic immunosuppressive therapy for rheumatoid arthritis. Our patient developed rapidly progressive global decline with clinical and radiographic findings suggestive of PML, but JC virus PCR in CSF was negative. …”
Get full text

The effects of magnesium supplementation in autoimmune rheumatic diseases by Aaron Lerner, Jozélio Freire de Carvalho, Carina Benzvi, Motti Haimi

“…Only one study fulfilled the inclusion criteria and demonstrated that 300 mg/day of oral magnesium reduced insulin resistance in rheumatoid arthritis patients. The lack of studies on this subject shows that additional studies are required to understand the causal relationship between magnesium supplementation and disease treatment.…”
Get full text

Leukocytoclastic Vasculitis in a Patient with Ankylosing Spondylitis by Senol Kobak, Hatice Yilmaz, Ahmet Karaarslan, Murat Yalcin

“…His physical examination revealed that he had arthritis in his right ankle, purpuric skin lesions in pretibial regions of both legs, and bilateral FABERE/FADIR positivity. …”
Get full text

QSAR modeling of benzoquinone derivatives as 5-lipoxygenase inhibitors by T.K. Shameera Ahamed, Vijisha K. Rajan, K. Muraleedharan

“…The inhibitors of 5-LOX control the overproduction of pro-inflammatory mediators known as leukotrienes (LTs) and thus have therapeutic relevance in the treatment of various diseases like asthma, rheumatoid arthritis, inflammatory bowel disease and certain types of cancers. …”
Get full text