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Argonaute2 and Argonaute4 Involved in the Pathogenesis of Kawasaki Disease via mRNA Expression Profiles
Published 2025-01-01Subjects: Get full text
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DICER1: The Argonaute Endonuclease Family Member and Its Role in Pediatric and Youth Pathology
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Argonaute2 modulates megakaryocyte development and sex-specific control of platelet protein expression and reactivity
Published 2025-01-01Subjects: Get full text
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Study of miRNA Based Gene Regulation, Involved in Solid Cancer, by the Assistance of Argonaute Protein
Published 2016-09-01Subjects: “…Argonaute…”
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Analysis of Argonaute Complex Bound mRNAs in DU145 Prostate Carcinoma Cells Reveals New miRNA Target Genes
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Advances in PIWI-piRNA function in female reproduction in mammals
Published 2024-11-01“…PIWI-interacting RNAs (piRNAs), which associate with PIWI clade Argonaute proteins to form piRNA-induced <sc>silencing</sc> complexes (piRISCs) in germline cells, are responsible for maintaining genomic integrity and reproductive function through transcriptional or post-transcriptional suppression of transposable elements and regulation of protein-coding genes. …”
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Functions and applications of RNA interference and small regulatory RNAs
Published 2024-11-01“…This process involves Argonaute/small RNA (AGO/sRNA) complexes that target transcripts via sequence complementarity and modulate gene expression and epigenetic modifications. …”
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Transgenic plants as a model for studying еpigenetic regulation of gene expression
Published 2015-12-01“…They are copied into long dsRNAs and are processed by DICER into siRNAs. siRNAs are then methylated and loaded into the effector complex, whose main component is a protein of the Argonaute family. RNA polymerase V also transcribes the noncoding transcript of the target gene, but it serves as a scaf¬fold that interacts with siRNAs and that recruits proteins and enzymes responsible for DNA and histone methylation. …”
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The effect of salicylic and jasmonic acids on the activity of <i>SnAGO</i> genes in the fungus <i>Stagonospora nodorum</i> Berk. in <i>in vitro</i> culture and during infection o...
Published 2023-12-01“…RNA interference is a gene silencing mechanism that plays an important role in genetic regulation in a number of eukaryotes. Argonaute (AGO) proteins are central to the complex RNA interference system. …”
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Global Transcriptomic Analysis of Inbred Lines Reveal Candidate Genes for Response to Maize Lethal Necrosis
Published 2025-01-01“…Key findings included the identification of components of the plant innate immune system, such as differentially regulated R genes (mainly LRRs), and activation/deactivation of virus resistance pathways, including RNA interference (RNAi) via <i>Argonaute</i> (AGO), <i>Dicer-like proteins</i>, and the ubiquitin–proteasome system (UPS) via <i>RING/U-box</i> and <i>ubiquitin ligases</i>. …”
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NAPTUNE: nucleic acids and protein biomarkers testing via ultra-sensitive nucleases escalation
Published 2025-02-01“…The sensitivity is elevated to attomolar levels through the action of Pyrococcus furiosus Argonaute (PfAgo), which intensifies probe cleavage, thereby boosting both sensitivity and specificity within an innovative in-situ cascade circuit. …”
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Transcriptome, miRNA, and degradome sequencing reveal the leaf stripe (Pyrenophora graminea) resistance genes in Tibetan hulless barley
Published 2025-01-01“…Using RNA-seq, small RNA sequencing (miRNA-seq) combined with degradome sequencing (degradome-seq), four pairs associated with leaf-stripe miRNAs and target genes were obtained, namely Hvu-miR168-5p and Argonaute1 (HvAGO1), Hvu-novel-52 and growth-regulating factor 6 (HvGRF6), Hvu-miR6195 and chemocyanin-like protein (CLP), and Hvu-miR159b and gibberellin-dependent MYB (GAMYB). …”
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Comprehensive analysis of full genome sequence and Bd-milRNA/target mRNAs to discover the mechanism of hypovirulence in Botryosphaeria dothidea strains on pear infection with BdCV1...
Published 2019-06-01“…RNA-silencing components including two endoribonuclease Dicer, four argonaute (Ago) and three RNA-dependent RNA polymerase (RdRp) molecules were identified and expressed in response to mycovirus infection. …”
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Beyond DNA: An Integrated and Functional Approach for Classifying Germline Variants in Breast Cancer Genes
Published 2016-01-01Get full text
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Bi-level data-driven enterprise-wide optimization with mixed-integer nonlinear scheduling problems
Published 2025-03-01“…The results indicate that DOMINO-NOMAD consistently achieves superior performance compared to DOMINO-ARGONAUT by identifying lower planning costs and generating more feasible solutions across multiple runs. …”
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Non-coding parts of genomes as the basis of epigenetic heredity
Published 2017-11-01“…The evolutionary conservation of a complex enzymes Drosha, Dicer, Argonaut, RdRP and their homologues in all multicellular eukaryotes, and their absence in unicellular organisms supports this assumption. …”
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Comprehensive Analysis of microRNA Methylation Profiles and Determination of Their Functional Significance in Colorectal Cancer: A Study Protocol
Published 2023-12-01“…To understand the biological significance of methylated microRNAs, we will perform pathway enrichment analysis and molecular dynamics simulations to examine the binding of argonaut protein to the differentially methylated microRNAs and the structural changes involved. …”
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