Prevalence, Antimicrobial Susceptibility Pattern of Bacterial Isolates, and Associated Factors of Urinary Tract Infections among HIV‐Positive Patients at Hiwot Fana Specialized Uni... by Dadi Marami, Senthilkumar Balakrishnan, Berhanu Seyoum

“…The emergence of antimicrobial resistance is now widespread and poses a serious clinical threat. …”
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Evaluation of the Bacterial Infections and Antibiotic Prescribing Practices in the Intensive Care Unit of a Clinical Hospital in Romania by Sándor Szabó, Bogdan Feier, Alina Mărginean, Andra-Elena Dumitrana, Simona Ligia Costin, Cecilia Cristea, Sorana D. Bolboacă

“…<b>Introduction:</b> Healthcare-associated infections (HAIs) are associated with increased mortality, antimicrobial resistance, and high antibiotic use. <b>Methods</b>: The characteristics of bacterial resistance and antibiotic consumption in the intensive care unit (ICU) of a clinical hospital in Romania were evaluated. …”
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Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infection by Simone Giuliano, Jacopo Angelini, Floriana Campanile, Paola Conti, Sarah Flammini, Alberto Pagotto, Francesco Sbrana, Luca Martini, Denise D’Elia, Mohd H. Abdul-Aziz, Menino O. Cotta, Jason A. Roberts, Robert A. Bonomo, Carlo Tascini

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Major F plasmid clusters are linked with ColV and pUTI89-like marker genes in bloodstream isolates of Escherichia coli by Cameron J. Reid, Max L. Cummins, Steven P. Djordjevic

“…Abstract Background F plasmids are abundant in E. coli, carrying a variety of genetic cargo involved in fitness, pathogenicity, and antimicrobial resistance. ColV and pUTI89-like plasmids have drawn attention for their potential roles in various forms of extra-intestinal pathogenicity. …”
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The Prevalence and Risk Factors Associated with the Presence of Antibiotic Residues in Milk from Peri-Urban Dairy Cattle Farms in Kathmandu, Nepal by Erda E. Rame Hau, Minu Sharma, Bal K. Sharma Khanal, Peter D. Sly, Deirdre Mikkelsen, Nicholas Clark, Ricardo J. Soares Magalhães

“…<b>Background/Objectives:</b> The presence of antibiotic residues (ARs) in animal products such as milk can be an important driver of antimicrobial resistance in commensal and pathogenic bacteria. …”
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Molecular characterization of putative antibiotic resistance determinant and virulence factors genes of Acinetobacter baumannii strains isolated from intensive care unit patients i... by Faris A. Alanazi, Khalid S. Almaary, Turki M. Dawoud, Mohamed A. El-Tayeb, Yahya B. Elbadawi, Ayman S. Mubarak, Ali M. Somily

“…The resistance in A. baumannii is attributed to numerous factors, including antimicrobial resistance and virulence-determinant genes. Hence, the present study aimed to screen antibiotic resistance and virulence factors genes in 67 A. baumannii strains isolated from patients admitted to several hospitals in Riyadh City, Saudi Arabia. …”
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Antibacterial, Antibiofilm, and Efflux Pump Inhibitory Properties of the Crude Extract and Fractions from Acacia macrostachya Stem Bark by Akua Frema Barfour, Abraham Yeboah Mensah, Evelyn Asante-Kwatia, Cynthia Amaning Danquah, Daniel Anokwah, Silas Adjei, Michael Kwesi Baah, Merlin L. K. Mensah

“…This study justifies the use of A. macrostachya in the treatment of infections in traditional medicine and highlights its potential as a source of bioactive compounds that could possibly interact with some resistance mechanisms in bacteria to combat antimicrobial resistance.…”
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Designing a broad-spectrum multi-epitope subunit vaccine against leptospirosis using immunoinformatics and structural approaches by Guneswar Sethi, Guneswar Sethi, Young Kyu Kim, Su-Cheol Han, Jeong Ho Hwang, Jeong Ho Hwang

“…The rise of antimicrobial resistance and the inefficacy of existing vaccines highlight the urgent need for new preventive strategies.MethodsAn immunoinformatics approach was employed to design a multi-epitope subunit vaccine (MESV) against leptospirosis. …”
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Genomic characteristics and molecular epidemiology of MRSA from medical centers in Mexico: Results from the Invifar network. by Gabriela Echaniz-Avilés, Luis Ángel Núñez-García, Eduardo Rodríguez-Noriega, Consuelo Velázquez-Acosta, Luis Esaú López-Jácome, Eduardo López-Gutiérrez, Talia Pérez-Vicelis, Cristina Torres-Báez, Ulises Garza-Ramos, Nadia Rodríguez-Medina, Juan Manuel Barajas-Magallón, Rosario Vázquez-Larios, Aldo Rafael Silva-Gamiño, Rafael Franco-Cendejas, Adolfo Gómez-Quiroz, Elvira Garza-González

“…This study aims to determine the genomic characteristics of MRSA using whole-genome sequencing (WGS) data from medical centers in Mexico and to explore the associations between antimicrobial resistance genes and virulence factors.<h4>Methods</h4>This study included 27 clinical isolates collected from sterile sites at eight centers in Mexico in 2022 and 2023. …”
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Isolation, Identification, and Susceptibility Profile of E. coli, Salmonella, and S. aureus in Dairy Farm and Their Public Health Implication in Central Ethiopia by Umer Seid Geletu, Munera Ahmednur Usmael, Abdulmuen Mohammed Ibrahim

“…In addition to this, antimicrobial resistance profiles of the isolates were determined. …”
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Multicenter Surveillance of Pseudomonas aeruginosa Isolates From Blood: Clinical Distribution Characteristics and Antibiotic Resistance Trends in Hebei Province, China (2016&ndash;... by Qiang C, Liu X, Qin P, Wen H, Li Z, Yang J, Niu Y, Wang W, Ouyang Z, Zhao M, Li J, Zhang Y, Zhao J

“…Cuixin Qiang,1,&ast; Xiaoxuan Liu,1,&ast; Pu Qin,1 Hainan Wen,2 Zhirong Li,1 Jing Yang,1 Yanan Niu,1 Weigang Wang,1 Zirou Ouyang,1 Min Zhao,1 Jiayiren Li,1 Yulian Zhang,1 Jianhong Zhao1 1The Second Hospital of Hebei Medical University, Hebei Provincial Center for Clinical Laboratories, Shijiazhuang, Hebei, People’s Republic of China; 2Department of Laboratory Medicine, Affiliated Hospital of Chengde Medical University, Chengde, Hebei, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jianhong Zhao, The Second Hospital of Hebei Medical University, Hebei Provincial Center for Clinical Laboratories, Shijiazhuang, Hebei, People’s Republic of China, Tel +86 0311 66002711, Email zhaojh_2002@hebmu.edu.cnPurpose: To analyze the clinical distribution and antimicrobial resistance of Pseudomonas aeruginosa (P. aeruginosa) isolated from blood specimens in 75 hospitals in Hebei Province from 2016 to 2021 to aid in the rational selection of antimicrobial drugs.Patients and Methods: WHONET 5.6 and SPSS 24.0 were used to retrospectively analyze clinical distribution characteristics and variations in drug-resistance.Results: Between 2016 and 2021, 2208 P. aeruginosa strains were detected in blood specimens from Hebei Province. …”
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Investigating the Pulmonary Host Response of <i>Acinetobacter baumannii</i> Infection-Associated Pneumonia by Metagenomic Next-Generation Sequencing by Mu-Jung Chou, Chih-Hung Cheng, Hui-Ching Wang, Ming-Ju Tsai, Chau-Chyun Sheu, Wei-An Chang

“…Partek was used for investigating enriched functions and pathways related to the pulmonary host response to pneumonia caused by <i>A. baumannii</i> with NDM infection and <i>A. baumannii</i> without antimicrobial-resistant genes. The STRING was employed for identifying protein interaction pathways related to the pulmonary host response to pneumonia caused by <i>A. baumannii</i> without antimicrobial-resistant genes. …”
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Antimicrobial Potential of Secalonic Acids from Arctic-Derived <i>Penicillium chrysogenum</i> INA 01369 by Yulia A. Roshka, Natalia N. Markelova, Sofia D. Mashkova, Kseniya V. Malysheva, Marina L. Georgieva, Igor B. Levshin, Vladimir I. Polshakov, Alexander M. Arutyunian, Alexey S. Vasilchenko, Vera S. Sadykova

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Detection and Characterization of <i>Escherichia coli</i> and <i>Escherichia coli</i> O157:H7 in Human, Animal, and Food Samples from Kirkuk Province, Iraq by Hayman Abdullah Ameen Altaie, Maroua Gdoura Ben Amor, Burhan Ahmed Mohammed, Radhouane Gdoura

“…Suspected <i>E. coli</i> O157:H7 were confirmed serologically and tested for antimicrobial resistance and virulence genes (<i>stx1</i>, <i>stx2</i>, <i>eaeA</i>, and <i>hlyA</i>). …”
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Understanding the clinical and molecular epidemiological characteristics of carbapenem-resistant Acinetobacter baumannii infections within intensive care units of three teaching ho... by Pengyu Zhang, Jingchen Hao, Yafen Zhang, Junfeng Su, Guozhuang Sun, Jun Xie, Jian Hu, Guocai Li

“…Multilocus sequence typing and phylogenetic trees were used to assess the genetic similarity of isolates. Acquired antimicrobial resistance genes and virulence factors carried in the isolated group genome were analyzed by ResFinder, PubMLST and VFDB. …”
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Fecal carriage of carbapenemase and AmpC-β-lactamase producers among extended spectrum β-Lactamase-producing E. coli and Klebsiella spp. isolates in patients attending hospitals by Zakaria Garba, Isidore J. O. Bonkoungou, Namwin Siourimè Somda, Magloire H. Natama, Georges Somé, Lassana Sangaré, Nicolas Barro, Halidou Tinto

“…The emergence of carbapenem resistance among ESBL-PE strains exacerbates the antimicrobial resistance. However, data are very limited in developing countries as Burkina Faso. …”
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Shorter versus longer durations of antibiotic treatment for patients with community-acquired pneumonia: a protocol for a systematic review and meta-analysis by Gordon Guyatt, Arnav Agarwal, Mark Loeb, John Basmaji, Ya Gao, Maryam Ghadimi, Layla Bakaa, Luis Enrique Colunga Lozano, Saad Asif, Aninditee Das

“…Where concerns regarding antimicrobial resistance continue to grow internationally, this evidence summary may motivate new recommendations regarding shorter durations of therapy. …”
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Pharmacodynamic Profiling of Amoxicillin: Targeting Multidrug-Resistant Gram-Positive Pathogens <i>Staphylococcus aureus</i> and <i>Staphylococcus pseudintermedius</i> in Canine Cl... by Syed Al Jawad Sayem, Ga-Yeong Lee, Muhammad Aleem Abbas, Seung-Chun Park, Seung-Jin Lee

“…The rising threat of antimicrobial resistance (AMR) is a global concern in both human and veterinary medicine, with multidrug-resistant (MDR) pathogens such as <i>Staphylococcus aureus</i> and <i>Staphylococcus pseudintermedius</i> presenting significant challenges. …”
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The Epidemiology of Bloodstream Infections and Antimicrobial Susceptibility Patterns: A Nine-Year Retrospective Study at St. Dominic Hospital, Akwatia, Ghana by John Gameli Deku, Mavis Puopelle Dakorah, Sylvester Yao Lokpo, Verner N. Orish, Francis Abeku Ussher, Godsway Edem Kpene, Vida Angmorkie Eshun, Eunice Agyei, Waldermer Attivor, James Osei-Yeboah

“…Bloodstream infection and antimicrobial resistance are high in patients seeking healthcare in Akwatia. …”
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Epidemics In The 21st Century: A Multifaceted Challenge by Shawana Sharif

“…The silent yet pervasive threat posed by antimicrobial resistance looms large, rendering conventional treatments ineffective and elevating the urgency for novel therapeutic strategies. …”
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