Prospective surveillance study to detect antimalarial drug resistance, gene deletions of diagnostic relevance and genetic diversity of Plasmodium falciparum in Mozambique: protocol by Alexandra Wharton-Smith, Caterina Guinovart, Pedro Aide, Francisco Saute, Alfredo Mayor, Bryan Greenhouse, Baltazar Candrinho, Joshua L Proctor, Arantxa Roca-Feltrer, Clemente da Silva, Eduard Rovira-Vallbona, Craig Bonnington, Caitlin Bever, Arlindo Chidimatembue, Maria Rodrigues, Neide Canana, Paulo Arnaldo, Simone Boene, Sonia Enosse

“…This study aims to operationalise a functional malaria molecular surveillance system in Mozambique for guiding malaria control and elimination.Methods and analyses This prospective surveillance study seeks to generate Plasmodium falciparum genetic data to (1) monitor molecular markers of drug resistance and deletions in rapid diagnostic test targets; (2) characterise transmission sources in low transmission settings and (3) quantify transmission levels and the effectiveness of antimalarial interventions. The study will take place across 19 districts in nine provinces (Maputo city, Maputo, Gaza, Inhambane, Niassa, Manica, Nampula, Zambézia and Sofala) which span a range of transmission strata, geographies and malaria intervention types. …”
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Antimalarial Efficacy and Antioxidant Activity of Lophira lanceolata Stem Bark Ethanol Extract Using Plasmodium berghei Induced-Malaria in Swiss Albino’s Mice by Mounvera Abdel Azizi, Noumedem Anangmo Christelle Nadia, Yamssi Cedric, Ngouyamsa Nsapkain Aboubakar Sidiki, Gamago Nkadeu Guy-Armand, Djeussi Doriane Esther, Tientcheu Noutong Jemimah Sandra, Tako Djimefo Alex Kevin, Vincent Khan Payne

“…This study aimed of investigating the antimalarial and antioxidant activities of ethanol extract of Lophira lanceolata stem bark. …”
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Phytochemical Screening and In Vivo Antimalarial Activity of Two Traditionally Used Medicinal Plants of Afar Region, Ethiopia, against Plasmodium berghei in Swiss Albino Mice by Sibhatu Gebrehiwot, Mohammed Shumbahri, Amelework Eyado, Tilahun Yohannes

“…The results of this study provide support for the traditional therapeutic value and the reported antimalarial activity.…”
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In vitro antiplasmodial activity of six plants against chloroquine-sensitive and resistant strains of Plasmodium falciparum by Samuel Korsah

Subjects: “…In vitro antimalarial…”
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Application of a new highly multiplexed amplicon sequencing tool to evaluate Plasmodium falciparum antimalarial resistance and relatedness in individual and pooled samples from Dschang, Cameroon by Jacob M. Sadler, Alfred Simkin, Valery P. K. Tchuenkam, Isabela Gerdes Gyuricza, Isabela Gerdes Gyuricza, Abebe A. Fola, Kevin Wamae, Ashenafi Assefa, Ashenafi Assefa, Karamoko Niaré, Kyaw Thwai, Samuel J. White, William J. Moss, Rhoel R. Dinglasan, Sandrine Eveline Nsango, Christopher B. Tume, Jonathan B. Parr, Jonathan B. Parr, Jonathan B. Parr, Innocent Mbulli Ali, Jeffrey A. Bailey, Jeffrey A. Bailey, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano

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Hospital attendance, malaria prevalence and self-medication with an antimalarial drug before and after the start of COVID-19 pandemic in a sentinel site for malaria surveillance in Gabon by Denise Patricia Mawili-Mboumba, Fanny Bertrande Batchy Ognagosso, Noé Patrick M’Bondoukwé, Jacques Mari Ndong Ngomo, Bridy Chesly Moutombi Ditombi, Ahmed Adissa Agbanrin, Tatiana Nymane, Bedrich Pongui Ngondza, Reinne Moutongo Mouandza, Coella Joyce Mihindou, Dimitri Ardin Mabika Moussavou, Ornella Anaïse Mbang Nguema, Marielle Karine Bouyou-Akotet

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High School Students Are a Target Group for Fight against Self-Medication with Antimalarial Drugs: A Pilot Study in University of Kinshasa, Democratic Republic of Congo by Ramsès Kabongo Kamitalu, Michel Ntetani Aloni

“…In this series, self-prescribed antimalarial was very irrational in terms of dose and duration of treatment. …”
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Anemia, Thrombocytopenia, and Changes in Biochemical Parameters Occurring in Patients with Uncomplicated Plasmodium falciparum Malaria: Data Analysis from Antimalarial Efficacy-Randomized Trials in Dakar and Kaolack Regions, Senegal by Khadime Sylla, Roger Tine, Doudou Sow, Souleye Lelo, Annie Abiola, Jean Louis NDiaye, Magatte NDiaye, Kuaku Folly, Léon Amath NDiaye, Oumar Gaye, Babacar Faye

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Assessment of different genotyping markers and algorithms for distinguishing Plasmodium falciparum recrudescence from reinfection in Uganda. by Mwesigwa, Alex, Golumbeanu, Monica, Jones, Sam, Cantoreggi, L. Sara, Musinguzi, Benson, Nankabirwa, I. Joaniter, Bikaitwoha, Everd Maniple, Kalyango, N. Joan, Karamagi, Charles, Plucinski, Mateusz, Nsobya, L. Samuel, Nsanzabana, Christian, Byakika-Kibwika, Pauline

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Malaria treatment-related risks: prevalence and pattern of traumatic injection neuropathy in children attending physiotherapy clinic in northern Nigeria by Lawan Umar, Adamu Usman Gamawa, Babangida Shehu Bappah, Annur Abubakar

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Molecular Modeling of Antimalarial Agents by 3D-QSAR Study and Molecular Docking of Two Hybrids 4-Aminoquinoline-1,3,5-triazine and 4-Aminoquinoline-oxalamide Derivatives with the Receptor Protein in Its Both Wild and Mutant Types by Hanine Hadni, Mohamed Mazigh, El’mbarki Charif, Asmae Bouayad, Menana Elhallaoui

“…Modeling studies using 3D-QSAR and molecular docking methods were performed on a set of 34 hybrids of 4-aminoquinoline derivatives previously studied as effective antimalarial agents of wild type and quadruple mutant Plasmodium falciparum dihydrofolate reductase (DHFR). …”
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2-Amino-1,3,4-thiadiazoles as prospective agents in trypanosomiasis and other parasitoses by Serban Georgeta

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Recrudescence of Plasmodium malariae after Quinine by Irfanali R. Kugasia, Farhana K. Polara, Hussein Assallum

“…However, reports of its recrudescence after antimalarials are rare with only a handful of case reports in the literature. …”
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Levofloxacin-Induced Acute Hyperpigmentation Changes in a Chronic Kidney Disease Patient by Shakuntala S. Patil, Sachin M. Patil, Ryan Campbell, Manisha Singh, Matthew Plotkin

“…Causative medications include nonsteroidal; anti-inflammatory agents, antimalarials, antibiotics, psychotropics, amiodarone, and chemotherapeutic agents. …”
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Have there been efforts to integrate malaria and schistosomiasis prevention and control programs? A scoping review of the literature. by Claudia Duguay, Sydney Raduy, Engluy Khov, Natacha Protopopoff, Cindy Feng, Alison Krentel, Manisha A Kulkarni

“…Out of 6374, eight articles were included in the scoping review-three articles investigated the integration of mass drug administration for schistosomiasis with the administration of antimalarials, four articles investigated the effect of administering antimalarials on malaria, schistosomiasis, and their co-infection, and one article assessed the impact of an educational intervention on malaria and schistosomiasis knowledge and preventative behaviors. …”
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The dynamin-related protein PfDyn2 is essential for both apicoplast and mitochondrial fission in Plasmodium falciparum by Alexander A. Morano, Wei Xu, Francesca M. Navarro, Neeta Shadija, Jeffrey D. Dvorin, Hangjun Ke

“…By demonstrating its necessity for the proper division of both the apicoplast and the mitochondria, this study highlights PfDyn2 as a potential target for new antimalarials.…”
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COLORATION AND DISCOLORATION OF OLVEOLAR BONE AND TOOTH ENAMEL CAUSED BY MEDICATION by Giurgiu Cristian Levente, George Morarasu, Nicolae Baranov, Pogăcian-Maier Alexandra-Camelia, Radu-Mircea Sireteanu-Cucui, Cristina Pipa, Alina Monica Miftode, Alina Stefanache

“…Fluoride can cause enamel hypomineralization, resulting in fluorosis. Antimalarials and iron supplements cause extrinsic stains due to complex formation with enamel minerals. …”
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Antiplasmodial Compounds from Millettia Dura. by Buyinza, Daniel, Derese, Solomon, Ndakala, Albert

“…Higher plants have produced single line antimalarials and given important lead molecules. On this basis, flavonoids isolated from millettia dura by chromatographic techniques were screened againest W2 and D6 strains of plasmoduim falcipalum. …”
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Real-world treatment patterns and clinical characteristics in patients with moderate-to-severe systemic lupus erythematosus: an analysis of the SLE Prospective Observational Cohort... by Raj Tummala, Richard A Furie, Laurent Arnaud, Eric F Morand, Martin Aringer, Stephanie Chen, Barnabas Desta, Alberta Hoi, Bo Ding, Christine Peschken, Jonatan Hedberg, Tina Grünfeld Eén, Alessandro Sorrentino, Danuta Kielar

“…Disease activity (SLE Disease Activity Index 2000 (SLEDAI-2K)), average oral glucocorticoid dose and use of other treatments—specifically antimalarials, biologics and immunosuppressants—were measured over time. …”
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Comparative-effectiveness research of COVID-19 treatment: a rapid scoping review by Sharon E Straus, Jesmin Antony, Andrea C Tricco, Rachel Warren, Erin Macdonald, Ba Pham, Milan Patel, Fatemeh Yazdi, Amruta Radhakrishnan, Marco Ghassemi, Patricia Rios, Chantal Williams, Naveeta Ramkissoon, Matthew P Muller, Nazia Darvesh, Gordon V Cormack, Maura R Grossman, Melissa Kampman, Reid Robson

“…The most common therapeutic categories involving multiple drugs were antimalarials/antibiotics (16%), steroids/non-steroidal immunosuppressants (9%) and antimalarials/antivirals/antivirals (7%). …”
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