Impact of a Multimodal Antimicrobial Stewardship Program on Pseudomonas aeruginosa Susceptibility and Antimicrobial Use in the Intensive Care Unit Setting by Douglas Slain, Arif R. Sarwari, Karen O. Petros, Richard L. McKnight, Renee B. Sager, Charles J. Mullett, Alison Wilson, John G. Thomas, Kathryn Moffett, H. Carlton Palmer, Harakh V. Dedhia

“…Despite variability in antibiotic usage from the stewardship efforts, we were overall unable to show statistical relationships with P. aeruginosa resistance rate. Conclusion. Antibiotic resistance in the ICU setting is complex. Multimodal stewardship efforts attempt to prevent resistance, but such programs clearly have their limits.…”
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Transition from irrigation with untreated wastewater to treated wastewater and associated benefits and risks by Benjamin J. Heyde, Melanie Braun, Leila Soufi, Kathia Lüneberg, Sara Gallego, Wulf Amelung, Katharina Axtmann, Gabriele Bierbaum, Stefanie P. Glaeser, Elisabeth Grohmann, René Arredondo-Hernández, Ines Mulder, Dipen Pulami, Kornelia Smalla, Christiane Zarfl, Christina Siebe, Jan Siemens

“…While this transition reduces many health risks, it may decrease crop yields, and soil carbon storage, cause a release of accumulated pollutants from soils, and increase the spread of antibiotic resistance in the environment. A holistic view on multiple SDGs is necessary to maximize benefits and minimize risks of wastewater treatment for irrigation.…”
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Tetracycline and chloramphenicol exposure induce decreased susceptibility to tigecycline and genetic alterations in AcrAB-TolC efflux pump regulators in Escherichia coli and Klebsi... by Nian Anwar Nasralddin, Mehri Haeili, Sasan Karimzadeh, Fatemeh Alsahlani

“…Unaltered acrB expression level in some strains indicates possible contribution of other efflux pumps or non-efflux-based mechanisms in the development of multiple- antibiotic resistance phenotype.…”
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Hospital-Based Air-Borne and Surface-Borne Bacterial Pathogens and Their Antimicrobial Profiles in Wolaita Sodo, Southern Ethiopia by Chemere Madebo, Admasu Haile, Temesgen Eticha, Fithamlak Solomon

“…A 12.5–100% range of antibiotic resistance levels was detected for all Gram-negative surface-borne bacterial pathogens. …”
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Molecular genetic and bacteriological methods of bovine mycoplasmosis diagnosis by E. V. Remizova, A. V. Gorbatov, L. K. Semina, Z. A. Skulyabina, N. V. Shmidt, G. A. Baldicheva, N. N. Avduevskaya

“…In addition, during microbiological testing, it is possible to assess the antibiotic resistance of mycoplasma isolates, thereby developing an optimal and high-quality scheme of the disease treatment and prevention.…”
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Genotypic and Phenotypic Characterizations of Methicillin-Resistant Staphylococcus aureus (MRSA) on Frequently Touched Sites from Public Hospitals in South Africa by Siyethaba Mkhize, Daniel G. Amoako, Christiana O. Shobo, Oliver T. Zishiri, Linda A. Bester

“…This study aimed to ascertain the prevalence, genetic relatedness, antibiotic resistance, and virulence profile of MRSA on some frequently touched hospital sites in South Africa. …”
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Changes in incidence and epidemiology of antimicrobial resistant pathogens before and during the COVID-19 pandemic in Germany, 2015–2022 by Jonathan H. J. Baum, Achim Dörre, Felix Reichert, Ines Noll, Marcel Feig, Tim Eckmanns, Mirco Sandfort, Sebastian Haller

“…Methods We used two independent datasets, statutory surveillance and laboratory-based Antibiotic Resistance Surveillance (ARS). We included statutory notifications of infections/colonisations of carbapenem-resistant Acinetobacter spp., Klebsiella pneumoniae, Escherichia coli (CRA/CRKP/CREC) and invasive MRSA. …”
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Prevalence, Risk Factors, and Antimicrobial Resistance Profiles of Thermophilic Campylobacter Species in Humans and Animals in Sub-Saharan Africa: A Systematic Review by Noel Gahamanyi, Leonard E. G. Mboera, Mecky I. Matee, Dieudonné Mutangana, Erick V. G. Komba

“…Electronic databases, namely, PubMed, Google Scholar, Research4life-HINARI Health, and Researchgate.net, were searched using the following search terms “thermophilic Campylobacter,” “Campylobacter jejuni,” “Campylobacter coli,” “diarrhea/diarrhoea,” “antimicrobial resistance,” “antibiotic resistance,” “humans,” “animals,” “Sub-Saharan Africa,” and “a specific country name.” …”
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In vitro evaluation of the antibacterial effects of monomer components of Pithecellobium clypearia against aquatic pathogens and synergy with enrofloxacin by Wenhao Wu, Jiahao Zhang, Xiaoyin He, Wei Li, Chun Liu, Biao Jiang, Youlu Su

“…These compounds demonstrate greater efficacy against the multi-drug resistant Aeromonas schubertii strain WL23R compared to the sensitive A. schubertii strain WL23S, indicating their potential in combating antibiotic resistance. Additionally, the combination of pyrogallol, luteolin, and tannic synergy with enrofloxacin (ENR) enhanced the potency of existing antimicrobials and potentially reducing dosage needs. …”
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Anti-motilities and anti-biofilm effects of Ageratum conyzoides L. methanol extract by Eli Compaoré, Moussa Compaoré, Vincent Ouédraogo, Ablassé Rouamba, Alimata Bancé, Mignini R. Dofini, Martin Kiendrebeogo

“…Background: Infectious diseases are one of the leading causes of death worldwide because of antibiotic resistance. Ageratum conyzoides is one of the antimicrobial medicinal plants that is being used to fight various multi-resistant pathogenic bacteria in Burkina Faso. …”
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Computational analysis of Allium sativum compounds to identify thermolabile hemolysin inhibitors against Vibrio alginolyticus in shrimp by Sayed Mashequl Bari, Nafees Bin Reza, Meamaching Marma, Sk. Foisal Ahmed, Md Arif Hussain, Md Naimuddin Jabed, Md Alomgir Hossain, Maria Manzoor, Md Saiful Alam

“…The widespread use of antibiotics in shrimp aquaculture to treat bacterial diseases has raised concerns about antibiotic resistance. As a result, alternative treatments, such as plant extract phytochemicals are being explored to mitigate these risks. …”
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Antibiotic exposure is associated with minimal gut microbiome perturbations in healthy term infants by Alain J. Benitez, Ceylan Tanes, Elliot S. Friedman, Joseph P. Zackular, Eileen Ford, Jeffrey S. Gerber, Patricia A. DeRusso, Andrea Kelly, Hongzhe Li, Michal A. Elovitz, Gary D. Wu, Babette Zemel, Kyle Bittinger

“…Antibiotic exposure was not associated with an increase in antibiotic resistance gene abundance or with differences in microbiome-derived fecal bile acid composition. …”
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Safety of transtympanic application of probiotics in a chinchilla animal model by Carol Nhan, Aren Bezdjian, Shyamali Saha, Satya Prakash, Lily H. P. Nguyen, Sam J. Daniel

“…Abstract Background Chronic suppurative otitis media can be recalcitrant and difficult to treat, particularly with the increasing occurrence of antibiotic resistance. Lactobacillus plantarum is a probiotic that has been shown to decrease S. aureus and P. aeruginosa growth in wounds, making it a good candidate for the treatment of chronic suppurative otitis media. …”
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Prevalence and predictors of self-medication practices among adult household members in Hosanna town, Hadiya zone, central Ethiopia by Sentayehu Admasu Saliya, Awoke Girma Hailu, Sisay Foga Sebro, Misgana Desalegn Menesho

“…Excessive and inappropriate self-medication practice can lead to recurrent infections and increased antibiotic resistance, which is a major problem impacting morbidity and mortality worldwide. …”
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Epidemiology, mechanisms, and clinical impact of bacterial heteroresistance by Linna Xu, Xiaofen Mo, Hui Zhang, Fen Wan, Qixia Luo, Yonghong Xiao

“…This review underscores the critical importance of understanding and addressing bacterial heteroresistance in the ongoing fight against antibiotic resistance and infectious diseases.…”
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Bloodstream infections at a tertiary hospital in the Gambia - a one-year retrospective study by Paul Rahden, Ebrima Barrow, Haddy Bah, Sheikh Omar Bittaye, David Nygren, Abdoulie Badjan

“…Extended-spectrum beta-lactamases (ESBL) were seen in 36/40 (90%) of Klebsiella spp. and in 16/28 (57%) of other bacteria within the Enterobacterales order. Acquired antibiotic resistance, beyond wild-type, was reported in 17/20 (85%) of Pseudomonas spp. and 16/19 (84%) of Acinetobacter spp. …”
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Characteristic and Antimicrobial Resistance of Bacillus cereus Group Isolated from Food in Poland by Joanna Kowalska, Elżbieta Maćkiw, Dorota Korsak, Jacek Postupolski

“…This study delivers practical information on antibiotic resistance and the frequency of toxin genes among strains isolated from food.…”
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Antimicrobial susceptibility patterns of pathogens isolated from clinical specimens at a tertiary care hospital in Bangladesh, 2020–2023 by Mohammad Kamruzzaman, Fahim Alam Nobel, Saiful Islam, Amiyo Haider, Mohammad Nasir Uddin, Mohammod Johirul Islam

“…The objective of the study was to determine the profile of bacteria and antibiotic resistance patterns of various clinical specimens at a tertiary care hospital in Mymensingh, Bangladesh from January 2020 to December 2023. …”
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Evaluation of the Synergistic Antimicrobial Activity of Essential Oils and Cecropin A Natural Peptide on Gram-Negative Bacteria by Filippo Fratini, Chiara Pecorini, Ilaria Resci, Emma Copelotti, Francesca Paola Nocera, Basma Najar, Simone Mancini

“…In an era dominated by the phenomenon of antibiotic resistance, it is increasingly important to look for alternatives to synthetic antibiotics. …”
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Rapid detection of carbapenem-resistant Escherichia coli and carbapenem-resistant Klebsiella pneumoniae in positive blood cultures via MALDI-TOF MS and tree-based machine learning... by Xiaobo Xu, Zhaofeng Wang, Erjie Lu, Tao Lin, Hengchao Du, Zhongfei Li, Jiahong Ma

“…This rapid identification of CREC and CRKP reduces detection time and contributes to early warning and response to potential antibiotic resistance problems in the clinic. Clinical trial number Not applicable.…”
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