The Effects of Nigella Sativa (Black Seed) in Rhinosinusitis Subjects: A Systematic Review by Muhamad Najmi Muhamad Najemudin, Nurul Asyiqin Yusof

“…The assessment of potential bias in the studies incorporated the Joanna Briggs Institute (JBI) checklist for critical appraisal of human studies and the Systematic Review Centre for Laboratory Animal Experimentation (SYRCLE) tool for assessing bias in animal studies. Results: Twelve studies were included in this study. …”
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The Successful Use of Inhaled Nitric Oxide in the Management of Severe Hepatopulmonary Syndrome after Orthotopic Liver Transplantation by Joshua Santos, Philip Young, Igor Barjaktarevic, Catherine Lazar, Irawan Susanto, Tisha Wang

“…Although the use of inhaled nitric oxide in patients with HPS has been sporadically reported in pediatric literature and in animal studies, to our knowledge, our cases are the first recorded in adult patients.…”
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Depth-electrode stimulation and concurrent functional MRI in humans: Factors influencing heating with body coil transmission by Hiroyuki Oya, Ralph Adolphs, Matthew A. Howard, J. Michael Tyszka

“…Widely used to map effective functional connectivity in animal studies, its application to the human brain has been limited due to safety concerns. …”
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Clinical outcomes and long-term efficacy of high tibial osteotomy in treating knee instability: An updated systematic review by Mustamsir Edi, Aji Aulia Pandu, Adiwangsa Ahmad Abdilla, Akmalizzan Azfar Ahnaf

“…Exclusion criteria included animal studies, non-knee joint studies, and reviews. Data on patient demographics, follow-up duration, subjective and objective outcomes, and complications were extracted. …”
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The influence of the pharmacodynamic properties of drugs on indications for their use: Sodium-glucose cotransporter 2 inhibitors (SGLT2 inhibitors) by Denda Nikola I., Maletin Nemanja Z., Atanasković Marko B., Vučković Biljana A., Rašković Aleksandar L.

“…Additionally, 4 original animal studies investigating the impact of SGLT2 inhibitors on laboratory mice were discovered. …”
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Effectiveness of positive allosteric modulators of metabotropic glutamate receptor 2/3 (mGluR2/3) in animal models of schizophrenia by David Olivares-Berjaga, Albert Martínez-Pinteño, Natalia Rodríguez, Sergi Mas, Constanza Morén, Eduard Parellada, Patricia Gassó

“…In this review, focusing on in vivo animal studies, we will specifically discuss the utilization of SZ animal models and the various methods employed to assess animal behaviour before summarising the evidence obtained to date in the field of mGluR2/3 PAMs. …”
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Therapeutic potential of phytocompounds of Bacopa monnieri (L.) Wettst (literature review) by O.O. Nikitina, D.S. Tsyba

“…Using machine learning, the prospects for using the main compounds of bacopa to create drugs were calculated taking into account the ATC classification, their biological effects and alternative plant sources were given. Experimental animal studies of whole aqueous or ethanolic extracts of B. monnieri have been found to support a cognitive enhancement effect. …”
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Liver Resection Promotes (Regulates) Proinflammatory Cytokines in Patients with Hepatocellular Carcinoma by Farshid Fathi, Behnam Sanei, Mazdak Ganjalikhani Hakemi, Reza F. Saidi, Abbas Rezaei

“…Background. Several animal studies have shown the roles of cytokines in regulating liver regeneration following liver resection (LR), which is a type of surgery designed to remove cancerous tumors from the liver. …”
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Systemic Inflammatory Cytokines Predict the Infectious Complications but Not Prolonged Postoperative Ileus after Colorectal Surgery by G. S. A. Boersema, Z. Wu, A. G. Menon, G. J. Kleinrensink, J. Jeekel, J. F. Lange

“…Postoperative ileus (POI) is common after surgery. Animal studies indicate that the POI mechanism involves an inflammatory response, which is also activated during postoperative complications. …”
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Nonparametric analysis of inter‐individual relations using an attention‐based neural network by Takashi Morita, Aru Toyoda, Seitaro Aisu, Akihisa Kaneko, Naoko Suda‐Hashimoto, Ikuma Adachi, Ikki Matsuda, Hiroki Koda

“…Abstract Social network analysis, which has been widely adopted in animal studies over the past decade, enables the revelation of global characteristic patterns of animal social systems from pairwise inter‐individual relations. …”
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Occurrence of severe cognitive impairment in elderly individuals with poor glycemic control Vs elderly individuals with good glycemic control or no DM: a case control study” by Basma Salman, Fatima Jehangir, Aroosa Jahan, Saira Aslam, Nadra Ansari

“… ABSTRACT: Background: There is substantiatial corroboration that diabetes (both T1DM and T2DM) plays an essential role in predisposition to cognitive decline thus leading to dementia in both human and animal studies. (1,2,3). Hypoglycemia has been associated with the increased risk of developing cognitive impairment. (4). …”
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Anti-Tumor Effects of <i>Vespa bicolor</i> Venom on Liver Cancer: In Vitro and In Vivo Studies by Yong-Hua Wu, Feng Xiong, Zheng-Wen Ou, Jing-An Wang, Jing Cui, Lin Jiang, Wen-Jian Lan

“…In vitro experiments evaluated VBV and its combination with DDP on HepG2 cell proliferation, invasion, migration, and apoptosis. Animal studies examined the tumor-suppressive effects, safety (hepatotoxicity and nephrotoxicity), and immune impact of these treatments in tumor-bearing mice. …”
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Association between Genetic Variants and Diabetes Mellitus in Iranian Populations: A Systematic Review of Observational Studies by Mehrnoosh Khodaeian, Samaneh Enayati, Ozra Tabatabaei-Malazy, Mahsa M. Amoli

“…The search terms were “gene,” “polymorphism,” “diabetes,” and “diabetic complications”; nephropathy, retinopathy, neuropathy, foot ulcer, and CAD (coronary artery diseases); and Persian equivalents. Animal studies, letters to editor, and in vitro studies were excluded. …”
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Lactic acid contributes to the emergence of depression-like behaviors triggered by blue light exposure during sleep by Yinhan Li, Xinhui Zou, Ying Ma, Jiaqi Cheng, Xiangmin Yu, Wenya Shao, Fuli Zheng, Zhenkun Guo, Guangxia Yu, Siying Wu, Huangyuan Li, Hong Hu

“…Lactic acid was relevant to depression with Mendelian randomization analysis. Moreover, animal studies demonstrated that exposure to blue light during sleep (BLS) induced depression-like behaviors in the animals. …”
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Plant Extracts in the Bone Repair Process: A Systematic Review by Lyvia Lopes Miranda, Vanessa de Paula Guimarães-Lopes, Luciana Schulthais Altoé, Mariáurea Matias Sarandy, Fabiana Cristina Silveira Alves Melo, Rômulo Dias Novaes, Reggiani Vilela Gonçalves

“…Essential criteria to in vivo animal studies were frequently underreported, suggesting publication bias. …”
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Effect of platelet-rich plasma on angiogenic and regenerative properties in patients with critical limb ischemia by Hamid Tanzadehpanah, Sima Nobari, Ava Jalalian Hoseini, Farzaneh Ghotbani, Mohsen Mehrabzadeh, Jamal Jalili shahri, Amirreza Alipour, Mohsen Sheykhhasan, Hamed Manoochehri, Susan Darroudi, Hanie Mahaki

“…PRP-derived growth factors have shown promising results in treating CLI, but well-controlled human research is scarce despite positive animal studies.…”
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Enhancing Infection Control in ICUS Through AI: A Literature Review by Aditya Amit Godbole, Paras, Maanya Mehra, Sumitaksha Banerjee, Poulami Roy, Novonil Deb, Sarang Jagtap

“…Methodology A comprehensive search of PubMed and Scopus was conducted for relevant articles up to January 2024, including case series, reports, and cohort studies. Animal studies and irrelevant articles were excluded, with a focus on those considered to have significant clinical relevance. …”
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The effect of light-emitting diode-mediated photobiomodulation therapy on orthodontic tooth movement: A literature review by Rashin Bahrami, Nariman Nikparto, Fateme Gharibpour, Maryam Pourhajibagher, Abbas Bahador

“…Five studies were included in the review, comprising two animal studies (ages 10 and 12 weeks) and three human studies (ages ranging from 15 to 17 years). …”
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Periodontal diseases in Down syndrome during childhood: a scoping review by Valentin Vergier, Anne-Margaux Collignon, Marjolaine Gosset, Anne-Laure Bonnet

“…The excluded articles were reviews, in vitro or animal studies, studies on teenagers or adults, and studies involving patients with disabilities other than DS. …”
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Assessing SPECT/CT for the identification of cartilage lesions in the knee joint: A systematic review by Larissa Rix, Samuel Tushingham, Karina Wright, Martyn Snow

“…Results: PubMed, Science Direct, Web of Knowledge, and NHS databases were searched for English language articles focusing on the diagnostic value of SPECT/CT for knee chondral lesions and knee pain. Animal studies, cadaver studies, comparator radiological technique other than SPECT/CT or patients with a pathology other than knee chondral lesions were excluded. …”
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