Dying occurs as a defined molecular progression in Drosophila rather than as nonspecific physiological collapse by Andrew W. Scott, Andrew P.K. Wodrich, Hitesh S. Chaouhan, Arvind K. Shukla, Kory Johnson, Philip G. McQueen, Edward Giniger

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Integrated spatial omics of metabolic reprogramming and the tumor microenvironment in pancreatic cancer by Hao Wu, Qiyao Zhang, Zhen Cao, Hongtao Cao, Mengwei Wu, Mengdi Fu, Tingping Huang, Xianlin Han, Xiaoyan Chang, Ziwen Liu

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Intercellular communication between hepatic stellate cells and myofibroblasts mediated by osteopontin and FGF18 promotes liver fibrosis by Takao Seki, Sachiko Komazawa-Sakon, Takashi Nishina, Tetuo Mikami, Hideo Yagita, Katsuhide Okunishi, Minoru Tanaka, Yuichi Tsuchiya, Hiroyasu Nakano

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Compositional variation in eye-infiltrating immune cells distinguishes human uveitis subtypes by Christian Concepcion, Yu Xia, Yulia Korshunova, Gregory W. Bligard, Amal Taylor, Michael A. Paley, Philip A. Ruzycki, Lynn M. Hassman

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Endothelial activating transcription factor 3 promotes angiogenesis and vascular repair in the mouse retina by Chihiro Ueda, Susumu Sakimoto, Masahito Yoshihara, Toru Takigawa, Akihiko Shiraki, Kaito Yamaguchi, Kosuke Shiki, Nobuhiko Shiraki, Shigetaka Kitajima, Yoshiaki Kubota, Yoko Fukushima, Kohji Nishida

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Single cell immune profiling in ankylosing spondylitis reveals resistance of CD8+ T cells to immune exhaustion by Michael Tang, Zoya Qaiyum, Melissa Lim, Robert D. Inman

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Tumor-derived colorectal cancer organoids induce a unique Treg cell population by directing CD4+ T cell differentiation by Sonia Aristin Revilla, Cynthia L. Frederiks, Stefan Prekovic, Enric Mocholi, Onno Kranenburg, Paul J. Coffer

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Multi-omics whole-genome characterization of the copy number landscape of metastatic pancreatic ductal adenocarcinoma by James T. Topham, Joanna M. Karasinska, Andrew Metcalfe, Hassan A. Ali, Steve E. Kalloger, Maya Kevorkova, Emma Titmuss, Gian Luca Negri, Sandra E. Spencer, Gun Ho Jang, Grainne M. O’Kane, Richard A. Moore, Andrew J. Mungall, Jonathan M. Loree, Faiyaz Notta, Julie M. Wilson, Oliver F. Bathe, Patricia A. Tang, Rachel Goodwin, Gregg B. Morin, Jennifer J. Knox, Steven Gallinger, Janessa Laskin, Marco A. Marra, Steven J.M. Jones, Daniel J. Renouf, David F. Schaeffer

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IFRD1 is required for maintenance of bladder epithelial homeostasis by Bisiayo E. Fashemi, Amala K. Rougeau, Arnold M. Salazar, Steven J. Bark, Rayvanth Chappidi, Jeffrey W. Brown, Charles J. Cho, Jason C. Mills, Indira U. Mysorekar

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Elucidating cardiomyocyte heterogeneity and maturation dynamics through integrated single-cell and spatial transcriptomics by Xiaoying Wang, Lizhi Cao, Rui Chang, Junwei Shen, Linlin Ma, Yanfei Li

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Potential applications of gene expression profiles obtained from circulating extracellular vesicles in breast cancer by Aritra Gupta, Siddharth Bhardwaj, Sayan Ghorai, Rosina Ahmed, Sanjit Agarwal, Geetashree Mukherjee, Kartiki V. Desai

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Transcriptomic insights into Candida albicans adaptation to an anaerobic environment by Karen D. Zeise, John R. Erb-Downward, Gary B. Huffnagle

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Targeting phospholipase PLAG-15 promotes healthy aging in C. elegans via lysosomal-related genes by Sanne van der Rijt, Marte Molenaars, Rashmi Kamble, Weisha Li, Bauke V. Schomakers, Adrie D. Dane, Simone W. Denis, Michel van Weeghel, Frédéric M. Vaz, Alessandra Tammaro, Georges E. Janssens, Arwen W. Gao, Riekelt H. Houtkooper

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Single‐Cell and Spatial Transcriptomics Reveals a Stereoscopic Response of Rice Leaf Cells to Magnaporthe oryzae Infection by Wei Wang, Xianyu Zhang, Yong Zhang, Zhe Zhang, Chang Yang, Wen Cao, Yuqin Liang, Qinzheng Zhou, Qian Hu, Yimai Zhang, Yu Wang, Yingying Xing, Wenfeng Qian, Nan Yao, Ning Xu, Jun Liu

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Integrated Single-Cell and Spatial Transcriptomic Analysis Identifies ISR-Related Genes Driving Immune Regulation in Parkinson’s Disease by Jiang H, Zhang X, Feng S, Feng W

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Dissection of tumoral niches using spatial transcriptomics and deep learning by Karla Paniagua, Yu-Fang Jin, Yidong Chen, Shou-Jiang Gao, Yufei Huang, Mario Flores

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Integrating Transcriptomic and Proteomic Data: IL‐27B as a Key Protein in the Development of Septic Cardiomyopathy—A Retrospective Study by Yifeng Mao, Qingqing Chen, Yongpo Jiang, Xijiang Zhang, Qin Si, Panpan Xu, Zhongheng Zhang, Cheng Zheng, Ronghai Lin

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Trajectories of macrophage ontogeny and reprogramming in cancer by Florent Duval, Joao Lourenco, Mehdi Hicham, Gaël Boivin, Alan Guichard, Celine Wyser-Rmili, Nadine Fournier, Nahal Mansouri, Michele De Palma

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Organoids as powerful models of endometrium epithelium in transcriptomic, cellular and functional mimicry by Martina Ciprietti, Celine Bueds, Hugo Vankelecom, Joris Vriens

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Emerging molecular approaches in stem cell biology by Amritha Jaishankar, Kent E. Vrana

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