Altered Anandamide Degradation in Attention Deficit Hyperactivity Disorder by J Gordon Millichap

Subjects: “…anandamide…”
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Inhibition by Anandamide of 6-Hydroxydopamine-Induced Cell Death in PC12 Cells by Katarzyna Mnich, David P. Finn, Eilis Dowd, Adrienne M. Gorman

“…Together, these data demonstrate antiapoptotic effects of anandamide and also suggest a role for activation of PI3K and inhibition of JNK signalling in anandamide-mediated protection against 6-OHDA.…”
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Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia. by Martin Kaczocha, Mario J Rebecchi, Brian P Ralph, Yu-Han Gary Teng, William T Berger, William Galbavy, Matthew W Elmes, Sherrye T Glaser, Liqun Wang, Robert C Rizzo, Dale G Deutsch, Iwao Ojima

“…The endocannabinoid anandamide (AEA) is an antinociceptive lipid that is inactivated through cellular uptake and subsequent catabolism by fatty acid amide hydrolase (FAAH). …”
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Effects of tumour necrosis factor α upon the metabolism of the endocannabinoid anandamide in prostate cancer cells. by Jessica Karlsson, Sandra Gouveia-Figueira, Mireille Alhouayek, Christopher J Fowler

“…In the present study we have investigated whether treatment of DU145 human prostate cancer cells affects anandamide (AEA) catabolic pathways. Additionally, we have investigated whether cyclooxygenase-2 (COX-2) can regulate the uptake of AEA into cells. …”
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Determination of the Endocannabinoids Anandamide and 2-Arachidonoyl Glycerol with Gas Chromatography-Mass Spectrometry: Analytical and Preanalytical Challenges and Pitfalls by Christian Lanz, Johan Mattsson, Felix Stickel, Jean-Francois Dufour, Rudolf Brenneisen

“… Background: The endocannabinoids anandamide (N-arachidonoyl ethanolamide [AEA]) and 2-arachidonoyl glycerol (2-AG) are involved in the regulation of neuronal, immune, metabolic, vascular, and reproductory functions. …”
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CamKIIα and VPAC1 Expressions in the Caudal Trigeminal Nucleus of Rats After Systemic Nitroglycerin Treatment: Interaction with Anandamide by Gábor Nagy-Grócz, Eleonóra Spekker, Tamás Körtési, Klaudia Flóra Laborc, Zsuzsanna Bohár, Annamária Fejes-Szabó, László Vécsei, Árpád Párdutz

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Anandamide Inhibits Vascular Smooth Muscle Migration, Endothelial Adhesion Protein Expression and Monocyte Adhesion of Human Coronary Artery Cells by Elane Blessing, Elisa Teichmann, Burkhard Hinz

Subjects: “…anandamide…”
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<i>Lactobacillus helveticus R0052</i> and <i>Bifidobacterium longum R0175</i> Supplementation: An Exploratory, Randomized, Placebo-Controlled Trial of Endocannabinoid and Inflammat... by Jakub Wiącek, Karolina Skonieczna-Żydecka, Igor Łoniewski, Chariklia K. Deli, Ioannis G. Fatouros, Athanasios Z. Jamurtas, Dominika Moszczyńska, Joanna Karolkiewicz

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Differential inhibitory effects of endocannabinoids on neuronal firing of mouse meningeal afferents by Georgii Krivoshein, Adriana Della Pietra, Juha Savinainen, Arn M. J. M. van den Maagdenberg, Rashid Giniatullin

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Major depressive disorder in children and adolescents is associated with reduced hair cortisol and anandamide (AEA): cross-sectional and longitudinal evidence from a large randomized clinical trial by Andreas Walther, Lukas Eggenberger, Rudolf Debelak, Clemens Kirschbaum, Isabelle Häberling, Ester Osuna, Michael Strumberger, Susanne Walitza, Jeannine Baumgartner, Isabelle Herter-Aeberli, Gregor Berger

“…This study explores the cross-sectional and longitudinal association between the ECS, specifically anandamide (AEA), and the HPA axis with its main effector cortisol and MDD status and severity in children and adolescents. …”
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The membrane domains of mammalian adenylyl cyclases are lipid receptors by Marius Landau, Sherif Elsabbagh, Harald Gross, Adrian CD Fuchs, Anita CF Schultz, Joachim E Schultz

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A preliminary investigation of tobacco co-use on endocannabinoid activity in people with cannabis use by Rachel A. Rabin, Joseph Farrugia, Ranjini Garani, Romina Mizrahi, Pablo Rusjan

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CB1 receptor and psychosis: friend, foe, or both by Jagadeesh S. Rao, Maria Alejandra Tangarife, Diego A. Rodríguez-Soacha, Ram Mukunda

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20:4-NAPE induced changes of mechanical sensitivity and DRG neurons excitability are concentration dependent and mediated via NAPE-PLD by Anirban Bhattacharyya, Daniel Vasconcelos, Diana Spicarova, Jiri Palecek

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Deciphering the interaction between N-palmitoyl-D-glucosamine and the endocannabinoidome by Aniello Schiano Moriello, Marco Allarà, Fabio Arturo Iannotti, Gabriele Marcolongo, Fabiana Piscitelli, Roberta Verde, Vincenzo Di Marzo, Stefania Petrosino

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Cannabinoids and cannabinoid-like compounds: Biochemical characterization and pharmacological perspectives by Oksana Yu. Kytikova, Yulia K. Denisenko, Tatyana P. Novgorodtseva, Ivan S. Kovalenko

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Time-Dependent Vascular Effects of Endocannabinoids Mediated by Peroxisome Proliferator-Activated Receptor Gamma (PPAR𝛾) by Saoirse E. O'Sullivan, David A. Kendall, Michael D. Randall

“…Vasorelaxation to NADA, but not anandamide, was inhibited by CB1 receptor antagonism (AM251, 1 𝜇M), and vasorelaxation to both anandamide and NADA was inhibited by PPAR𝛾 antagonism (GW9662, 1 𝜇M). …”
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Fatty acid amide hydrolase levels in brain linked with threat-related amygdala activation by Duncan GJ. Green, Duncan J. Westwood, Jinhee Kim, Laura M. Best, Stephen J. Kish, Rachel F. Tyndale, Tina McCluskey, Nancy J. Lobaugh, Isabelle Boileau

“…Background: Preclinical evidence suggests that increasing levels of the major endocannabinoid anandamide decreases anxiety and fear responses potentially through its effects in the amygdala. …”
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Involvement of cannabinoid receptors in depression of the putative nociceptive response in spinal cord preparations isolated from neonatal rats by Kayo Tsuzawa, Hiroshi Onimaru, Katsunori Inagaki, Masahiko Izumizaki

“…Abstract A metabolite of acetaminophen, AM404, which is an anandamide transporter inhibitor, induces analgesia mainly via activation of transient receptor potential channel 1 in the spinal cord, although the role of cannabinoid receptors remains to be studied. …”
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FAAH Modulators from Natural Sources: A Collection of New Potential Drugs by Catalin Nicoara, Filomena Fezza, Mauro Maccarrone

“…Recent research efforts have focused on modulating endogenous eCB levels, particularly through the inhibition of fatty acid amide hydrolase (FAAH), the main catabolic enzyme of the major eCB anandamide. Natural substances, including plant extracts and purified compounds, can inhibit FAAH and represent a promising area of pharmacological research. …”
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