SECOBISBENZYLISOQUINOLINE ALKALOIDS - CHEMISTRY AND PHARMACOLOGY: A REVIEW by Syed Fazal Hussain

“…A critical study on the structures of these alkaloids indicates that secobisbenzylisoquinoline alkaloids could be the first step towards catabolism of bisbenzylisoquinolines but unfortunately, very little pharmacological work has been carried out on secobisbenzylisoquinoline alkaloids. …”
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A systematic review of proaporphine alkaloids and a pharmacological update by Christian Bailly

Subjects: “…Alkaloids…”
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Mechanism of melanoma suppression by Prosopis juliflora derived alkaloids: Apoptosis induction and signaling pathway inhibition by Jasoda Choudhari, Snehal K. Nimal, Shridhar Chougule, Trupti Shinde, N.R. Dhatrak, Gopal C. Kundu, Rajesh N. Gacche

“…In this context, we identified alkaloid fractions derived from PJLME (PJLME-AF) as key agents in PJLME's cytotoxic effect against melanoma cells. …”
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Interaction of norsecurinine-type monomeric and dimeric alkaloids with α-tubulin: a molecular docking study by Gérard Vergoten, Christian Bailly

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Effects of typical plant growth regulator chlormequat chloride on alkaloidal compounds in Corydalis yanhusuo and molecular mechanisms by Zixuan Du, Jiayin Cao, Jie Meng, Heng Zhou, Qing Hu, Ling Li, Yun Liao, Shui Miao, Wenting Li, Shen Ji, Tongshuai Wang

“…Transcriptomic analysis also facilitates the identification of differential genes and enzymes associated with alkaloid production between the two groups. Chlormequat chloride significantly increased the yield of C. yanhusuo, but the content of the quantitatively abundant alkaloids decreased. …”
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First report of fatty acid-derived alkaloids produced by species of the ladybird genus Scymnus (Coccinellidae: Coleoptera) by Magro, Alexandra, Ramon-Portugal, Felipe, Touboul, David, Borges, Isabel, Hemptinne, Jean-Louis

“…The results of the GC-MS analyses suggest that Scymnus spp. produce azamacrolides, which are fatty acid-derived alkaloids.…”
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Virtual Screening, Toxicity Evaluation and Pharmacokinetics of Erythrina Alkaloids as Acetylcholinesterase Inhibitor Candidates from Natural Products by Permana A, Akili AWR, Hardianto A, Latip JB, Sulaeman AP, Herlina T

Subjects: “…erythrina alkaloid…”
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Priming bumble bees with caffeine, odour of the target crop, and a food reward, has minimal effects on fruit crop pollination and yield in a semi-commercial setup by Sarah Arnold, Celine Silva, Jan-Hendrik Dudenhöffer, David Hall, Dudley Farman, Felix Wäckers, Philip Stevenson, Michelle Fountain

Subjects: “…alkaloids…”
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Quantitative analysis of the effect of microtubule-targeting drugs on the microtubule cytoskeleton of breast cancer cells with different invasive properties by Michallet, Sophie, Bosc, Lauriane, Lafanechère, Laurence

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Thaliporphine from Berberis lycium Royle by Syed Fazal Hussain

“… Chemical studies on the aerial part of Berberis lycium Royle belonging to the family Berberidaceae resulted in the isolation of the aporphine alkaloid ‘Thaliporphine’, the structure of which was elucidated by using spectroscopic techniques such as 1H NMR, 13C NMR, DEPT-90, DEPT-135 and Mass spectrometry. …”
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Computational Study of Trisindoline 5 Against Overexpressed EGFR Protein on Breast Cancer Stem Cell by Nurhayati A.P.D., Fatoni M., Santoso M., Wati F.A.

“…Trisindoline is an indole trimer alkaloid natural compound that provide a cytotoxic effect on cancer cells. …”
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Multiproxy analysis exploring patterns of diet and disease in dental calculus and skeletal remains from a 19th century Dutch population by Bartholdy, Bjørn Peare, Hasselstrøm, Jørgen B., Sørensen, Lambert K., Casna, Maia, Hoogland, Menno, Historisch Genootschap Beemster, Henry, Amanda G.

“…The detection of plant-derived residues such as alkaloids and their metabolites in dental calculus provides direct evidence of consumption by individuals within a population. …”
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Effects of Prosopis farcta Root Extract in the Vascular Reactivity of Isolated Goat Coronary Artery by Rezhna Adil Rasheed, Ismail Salih Ibrahim Kakey

“…On the other hand, the extract tended to relax the CA rings through its antagonizing of Ca+2, reducing and inhibiting Ca+2 influx and release from internal stores and interfering with the voltage-operated Ca+2 channels through its alkaloid and flavonoid active compounds which suggested to be the most predicted mechanisms for the maintenance of vasodilating tone and coronary circulation of the PFRE in coronary artery.  …”
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In vitro and in vivo investigations of selected varieties of Areca catechu L - Phytochemical analysis, antiulcer, and wound healing activity by R. Deveswaran, D.J. Madhu Kumar, V. Madhavan, Soma Chaki, Misbah Khan, Govind R. Kadambi, B.V. Basavaraj, J. Anbu

“…Results: Phytochemical analysis of the selected arecanut revealed the presence of various compounds including alkaloids, phytosterols, fixed oils, saponins, and phenolic compounds. …”
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Comparison of effectiveness in smoking cessation using nicotine replacement therapy and electronic cigarettes by Adrianna Kopaczyńska, Katarzyna Szafrańska, Szymon Niemirka, Aleksandra Janiak, Kinga Dominiczak, Łukasz Grądalski, Filip Dębicki

“… Nicotine, a potent psychoactive alkaloid found in tobacco leaves, is recognized for its high addictive potential, contributing to over 8 million deaths annually according to the World Health Organization. …”
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Phytochemical Screening of Spermacoce Princeae from Ndorwa County Kabale District Uganda. by Muhumuza, James

“…In this study, qualitative phytochemical screening was done on different crude extracts (stems and leaves) of Spermacoce prince and the results revealed the presence of flavonoids, sterols, alkaloids, terpenoids, saponin,s and tannins in both leaves and stems, and absence of coumarins, steroids and glycosides in both leaves and stems. …”
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Proximate and Phytochemical Analysis of Leaves of Anthocleista vogelii ( Cabbage palm) by Emem Ikpeme Bassey, Effiong Bassey Bassey, Ugbor Ofunna, Pheobe Ikechukwu

“…The phytochemical screening indicated qualitatively the presence of alkaloids, saponins, flavonoids, polyphenols, tannins, reducing sugars, and the absence of phlobatanins, anthranoids. …”
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Antibacterial activity of 1 % Roselle flower nano-emulsion extract (Hibiscus sabdariffa) against peri-implantitis-related bacteria on orthodontic mini-implants: An in vitro study by Ridhofar Akbar Khusnul Abdillah, Theresia Indah Budhy, Ida Bagus Narmada, I Gusti Aju Wahju Ardani, Nastiti Faradilla Ramadhani, Ratri Maya Sitalaksmi, Muhammad Luthfi, Ninik Mas Ulfa, Albertus Putera Nugraha, Tengku Natasha Eleena binti Tengku Ahmad Noor, Alexander Patera Nugraha

“…Results: Roselle flower NE extract (1 %) possessed flavonoids, quinone, saponin, alkaloids, tannins, terpenoids, and steroids positively. …”
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Phytochemical Screening of the Roots, Stem, Leaves and Flowers of Tithonia Diversifolia For Antimicrobial Properties. by Baluku, Geoffrey Kapere

“…Results revealed the presence of flavonoids, saponins, tannins, alkaloids, terpenoids, steroids, carbohydrates, glycosides, anthraquinones, proteins, volatile oils, and reducing sugars. …”
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Phytochemical investigation on the seed of <i>Sphenostylis stenocarpa</i> (Hochst ex A. Rich.) Harms (Family Fabaceae) by BL Nyananyo, AL Nyingifa

“…Harms (Family Fabaceae) revealed the presence of the flavonoids (tricin, apigenin, chrysoeriol and genisten), tannin and alkaloids. The three putative varieties previously separated on the basis of seed colour were only distinguished on the amount of tannin present: white = 0.35, brown = 0.55 and red = 0.65. …”
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