Factors associated with breast lymphedema after adjuvant radiation therapy in women undergoing breast conservation therapy by Summer Sami Yono, Cara Cannella, Madeleine Gonte, Sanjay Rama, Simeng Zhu, Jenna Luker, Maristella S. Evangelista, Jessica Bensenhaver, Eleanor M. Walker, Dunya Atisha

“…The mean ± standard deviation age was 62.9 ± 11.1 years and the mean breast volume was 1352.0 ± 744.9 cm3. …”
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Dihydroquercetin attenuated Prevotella copri-caused intestinal injury by modulating gut microbiota and bile acids in weaned piglets by Long Wang, Ruizhi Hu, Siqi Ma, Xizi Yang, Jiatai Gong, Hongkun Xiang, Mingkun Shi, Xupeng Yuan, Liang Chen, Hongfu Zhang, Bie Tan, Xi He, Jianhua He, Shusong Wu

“…A total of 108 healthy Duroc × Landrace × Yorkshire weaned piglets, aged 21 d, were randomly allocated into 3 groups with 6 replicates and 6 piglets per replicate. …”
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Intravenous nicardipine and labetalol use in hypertensive patients with signs or symptoms suggestive of end-organ damage in the emergency department: a subgroup analysis of the CLU... by Brian Hiestand, Phillip Levy, W Frank Peacock, Brigitte M Baumann, Richard M Nowak, Amy Hsu, Joseph Varon, Chad M Cannon, David M Cline, Pierre Borczuk, Abhinav Chandra, Deborah B Diercks, Preeti Jois, Brian Kaminski, Jon W Schrock

“…Objective To compare the efficacy of Food and Drug Administration recommended dosing of nicardipine versus labetalol for the management of hypertensive patients with signs and/or symptoms (S/S) suggestive of end-organ damage (EOD).Design Secondary analysis of the multicentre prospective, randomised CLUE trial.Setting 13 academic emergency departments in the USA.Participants Eligible patients had two systolic blood pressure (SBP) measures ≥180 mm Hg at least 10 min apart, no contraindications to nicardipine or labetalol and predefined S/S suggestive of EOD on arrival.Interventions Medications were administered by continuous infusion (nicardipine) or repeat intravenous bolus (labetalol) for a study period of 30 min or until a specified target SBP ±20 mm Hg was achieved.Primary outcome measure Percentage of participants achieving a predefined target SBP range (TR) defined as an SBP within ±20 mm Hg as established by the treating physician.Results Of the 141 eligible patients, 49.6% received nicardipine, 51.7% were women and 81.6% were black. Mean age was 52.2±13.9 years. Median initial SBP did not differ in the nicardipine (210.5 (IQR 197–226) mm Hg) and labetalol (210 (200–226) mm Hg) groups (p=0.862). …”
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Two decades of recipient and donor referrals for heart transplantation to Groote Schuur Hospital, Cape Town, South Africa: A retrospective study by R Kanyongo, G Calligaro, B Cupido, J Scherman, A Brooks, C Ofoegbu, N Da Silva, A Ryan, M Mofamadi, K Seele, P Human, J Brink, P Zilla, T Pennel

“…A total of 625 recipients were referred for heart transplantation, with the majority being male (n=412; 65.9%), while gender was undocumented for 69 cases (11.0%). The mean age was 38.1 (14.6) years, and 153 (24.5%) were listed for transplant, while 215 (34.4%) were deemed ineligible for listing. …”
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Impact of bedroom light exposure on glucose metabolic markers and the role of circadian-dependent meal timing: A population-based cross-sectional study by Qi Li, Yu-xiang Xu, Xiu-zhen Lu, Yu-ting Shen, Yu-hui Wan, Pu-yu Su, Fang-biao Tao, Xin Chen, Ying Sun

“…Circadian-dependent meal timing, including the timing of meal relative to clock time and sleep time, was calculated from 24-h dietary records and sleep data. Results: The mean age of participants was 18.7 years, and 32.8 % were male. …”
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Co-creation and application of a framework for the de-prioritization of urban communities during insecticide-treated bed net mass campaigns for malaria prevention and control in Kw... by Ifeoma D. Ozodiegwu, Laurette Mhlanga, Eniola A. Bamgboye, Adeniyi F. Fagbamigbe, Cyril Ademu, Chukwu Okoronkwo, Joshua O. Akinyemi, Akintayo O. Ogunwale, IkeOluwapo O. Ajayi, Beatriz Galatas

“…Abstract Background Malaria continues to be a major cause of illness and death worldwide, particularly affecting children under the age of five and those living in high-burden countries like Nigeria. …”
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Time trends in mechanical thrombectomy (2017–2021): do real-world data reflect advances in evidence? by Christoph Riegler, Christoph Riegler, Viktoria Rücker, Regina von Rennenberg, Regina von Rennenberg, Kerstin Bollweg, Kerstin Bollweg, Bastian Cheng, Anna C. Alegiani, Fabian Flottmann, Marlena Schnieder, Marielle Ernst, Waltraud Pfeilschifter, Waltraud Pfeilschifter, Waltraud Pfeilschifter, Christoffer Kraemer, Ruben Mühl-Benninghaus, Steffen Tiedt, Steffen Tiedt, Lars Kellert, Hanna Zimmermann, Felix J. Bode, Felix J. Bode, Gabor C. Petzold, Gabor C. Petzold, Franziska Dorn, Jörg Berrouschot, Albrecht Bormann, Kathleen Bernkopf, Silke Wunderlich, Tobias Boeckh-Behrens, Martina Petersen, Lars Udo Krause, Stephan Lowens, Heinrich J. Audebert, Heinrich J. Audebert, Eberhard Siebert, Peter U. Heuschmann, Peter U. Heuschmann, Peter U. Heuschmann, Christian H. Nolte, Christian H. Nolte, Christian H. Nolte, Christian H. Nolte

“…Patients became older (median age from 76 [IQR: 65–82] to 77 [65–84 years]; ptrend = 0.02), and less severely affected (NIHSS from 15 [11–19] to 13 [8–18]; ptrend <0.001). …”
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Effect of zinc added to a daily small-quantity lipid-based nutrient supplement on diarrhoea, malaria, fever and respiratory infections in young children in rural Burkina Faso: a cl... by Elizabeth Yakes Jimenez, Sonja Y Hess, Souheila Abbeddou, Kenneth H Brown, Jean-Bosco Ouedraogo, Jérôme W Somé, Zinéwendé P Ouédraogo, Rosemonde M Guissou, Stephen A Vosti

“…We assessed the effects of different amounts and sources of zinc on the frequency of diarrhoea, malaria, fever and RTI in young children.Design, setting and populations This community-based, double-blind, placebo-controlled, cluster-randomised trial of 2435 children 9 months of age was carried out between April 2010 and July 2012 in rural southwestern Burkina Faso.Interventions Participants were randomly assigned at the concession level to receive daily 1 of 4 interventions for 9 months: (1) 20 g small-quantity lipid-based nutrient supplement (SQ-LNS) without zinc and placebo tablet, (2) 20 g SQ-LNS with 5 mg zinc and placebo tablet, (3) 20 g SQ-LNS with 10 mg zinc and placebo tablet or (4) 20 g SQ-LNS without zinc and 5 mg zinc tablet. …”
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Associations of carbohydrate quality and cardiovascular risk factors vary among diabetes subtypes by Katharina S. Weber, Sabrina Schlesinger, Janina Goletzke, Klaus Straßburger, Oana-Patricia Zaharia, Sandra Trenkamp, Robert Wagner, Wolfgang Lieb, Anette E. Buyken, Michael Roden, Christian Herder, for the GDS group

“…Methods Participants of the German Diabetes Study (GDS) (recent-onset diabetes (n = 487) and 5-years thereafter (n = 209)) were allocated into severe autoimmune diabetes (SAID, 35%), severe insulin-deficient diabetes (SIDD, 3%), severe insulin-resistant diabetes (SIRD, 5%), mild obesity-related diabetes (MOD, 28%), and mild age-related diabetes (MARD, 29%). Dietary glycemic index (GI), glycemic load (GL), and intake of higher- (≥ 55) and low-GI (< 55) foods, dietary fiber, and total sugar were derived from a validated food frequency questionnaire and cross-sectionally associated with cardiovascular risk factors (blood lipids, subclinical inflammation, blood pressure, fatty liver index) using multivariable linear regression analysis for subtypes with prevalences ≥ 10%. …”
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Predictive value of the perivascular fat attenuation index for MACE in young people suspected of CAD by Yani Yu, Dongkai Shan, Xi Wang, Zinuan Liu, Guanhua Dou, Junjie Yang, Yuqi Liu, Yundai Chen

“…Method A retrospective analysis was performed on adults aged ≤ 45 years who underwent CCTA due to suspected CAD between 2015 and 2016 and who were followed up for at least 5 years following their visit (n = 503). …”
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Dupilumab in children with eosinophilic esophagitis: a retrospective multicenter study by Mohammed Hasosah, Ghassan Sukkar, Asharf AlSahafi, Ali Zaidan, Nouf Ghous, Abdulmajed Alshahrani, Ziyad Al Zahrani, Naif Hasosah, Mansour Qurashi, Loie Goronfolah, Ali Alsharief, Nagla Kamal

“…The study population comprised seven boys (64%) and four girls (36%). The median age at presentation was 11.6 years (8–13 years). …”
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Estudio psicométrico del cuestionario de intenciones emprendedoras en jóvenes mexicanos - Psychometric study of the entrepreneurial intentions questionnaire in Mexican youth by Ignacio Norambuena, Felipe Quintano, Leonor Riquelme, José Sepúlveda, Cristina Tavera, Selene Pérez, Crisóforo Álvarez, Roque López

“…Methodology: this psychometric research included 519 university students from the state of Morelos, Mexico, with 40% male and 60% female participants, aged 18 to 29 years (SD = 4.257). Exploratory (EFA) and confirmatory factor analyses (CFA) were conducted to assess the scale’s structure and validity. …”
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Tick-borne encephalitis vaccination in persons with a recent history of Lyme borreliosis: Insights from a Knowledge, Attitudes and Behaviour survey in Bavaria, Germany by Stefanie Böhm, Andreas Beyerlein, Volker Fingerle, Merle M. Böhmer, Manfred Wildner

“…Of 228 participants who provided further details, 142 (62 %) reported to have received a regular booster vaccination. Apart from age category and TBD-specific knowledge level, vaccination status was not associated with any other sociodemographic or residence-specific factors, outdoor behaviours, occupational exposure, or prior experiences with ticks or TBDs. …”
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Characteristics and outcomes of women using emergency medical services for third-trimester pregnancy-related problems in India: a prospective observational study by Jennifer A Newberry, Corey B Bills, Elizabeth A Pirrotta, Matthew C Strehlow, G V Ramana Rao, Hyeyoun (Elise) Min, Ann E Evensen, Lawrence Leeman, S V Mahadevan

“…Interfacility transfers, patients absent on ambulance arrival and patients refusing care were excluded.Main outcome measures Emergency medical technician (EMT) interventions, method of delivery and death.Results The median age enrolled was 23 years (IQR 21–25). Women were primarily from rural or tribal areas (1550/1684 (92.0%)) and lower economic strata (1177/1684 (69.9%)). …”
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First detection and molecular characterization of porcine epidemic diarrhea virus (PEDV) in India: evidence of a new variant in Karnataka by Jagadish B. Hiremath, M. Swathi, R. Ramamoorthy, M. Shijili, Damini Sharma, Divakar Hemadri, H. B. Chethankumar, K. P. Suresh, Sharanagouda S. Patil, Shivasharanappa Nayakvadi, S. P. Satheesha, B. R. Shome, Baldev Raj Gulati

“…Abstract Background Porcine epidemic diarrhea (PED) is a significant pig disease causing high mortality in suckling pigs and high morbidity across all age groups. It is highly prevalent in Southeast Asia, posing a threat of transboundary transmission to India. …”
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Effects of Mixing Tree Species on Soil Enzyme Activity and Carbon-Use Efficiency in Eroded Masson Pine Forest by WANG Man, JIANG Yongmeng, ZHANG Shiliang, ZHANG Jinxiu, ZHENG Linmin, ZENG Zhiwei, LYU Maokui, XIE Jinsheng

“…[Results] (1) With the increase of restoration years, soil acid phosphatase (AP) and β-glucosidase (βG) activities were significantly reduced, while C∶NEEA (βG∶NAG), vector length (VL) and vector angle (VA) of the mixed forest were lower than that of pure forest, while C∶PEEA (βG∶AP) and N∶PEEA (NAG∶AP) showed the opposite trend, indicating that long-term mixing is beneficial to alleviate the carbon limitation and phosphorus limitation of microorganisms. (2) Mixing was beneficial to improve CUE and significantly increased with the increase of forest age. Specifically, compared with that of Y39-CF and Y19-MF, CUE of Y39-MF significantly increased by 200.00% and 136.84%, respectively. (3) By analyzing the characteristics of soil enzyme activity and the relationship between CUE and environmental factors, it was found that soil carbon, nitrogen and phosphorus availability was an important influencing factor, mainly affecting AP activity, C∶PEEA, N∶PEEA, VL, VA and CUE, while the stoichiometric ratio of soil nutrients mainly affected βG activity and C∶NEEA. (4) The results of redundancy analysis (RDA) showed that the ratio of fungi and bacteria mainly affected the characteristics of soil enzyme activity and CUE in the mixed forest, while the main influencing factors in pure forest were actinomyces and Gram-negative bacteria. …”
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Association between Air Pollution and Risk of Hospital Admission for Pediatric Pneumonia in a Tropical City, Kaohsiung, Taiwan by Peng-Huei Liu, Kuo-Chen Huang, Yu-Lun Tseng, I-Min Chiu, Hsiu-Yung Pan, Fu-Jen Cheng

“…The medical records of non-traumatic patients under 17 years of age who had visited the ED between 2008 to 2013, with a principal diagnosis of pneumonia were extracted. …”
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Lifestyle risk factors for overweight and obesity among rural Indian adults: a community-based prospective cohort study by Rajesh Kumar Rai, Sabri Bromage, Jan-Walter De Neve, Anamitra Barik

“…To address this evidence gap, this study used cohort data (baseline: 2018–19, follow-up: 2022–23) from the Birbhum Population Project (West Bengal, India) to analyse lifestyle risk factors and their association with incidence and remission of overweight/obesity among adults aged ≥18 years (sample: 8,974). Modified Poisson regression model was employed to attain the study objective. …”
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Randomised controlled trial of topical kanuka honey for the treatment of rosacea by James Fingleton, Mark Weatherall, Richard Beasley, Irene Braithwaite, Janwillem Kocks, Mark Holliday, Andrew Corin, Colin Helm, Davitt Sheahan, Barney Montgomery, Judith Riley, Anna Hunt, Christopher Tofield

“…Objective To investigate the efficacy of topical 90% medical-grade kanuka honey and 10% glycerine (Honevo) as a treatment for rosacea.Design Randomised controlled trial with blinded assessment of primary outcome variable.Setting Outpatient primary healthcare population from 5 New Zealand sites.Participants 138 adults aged ≥16, with a diagnosis of rosacea, and a baseline blinded Investigator Global Assessment of Rosacea Severity Score (IGA-RSS) of ≥2. 69 participants were randomised to each treatment arm. 1 participant was excluded from the Honevo group, and 7 and 15 participants withdrew from the Honevo and control groups, respectively.Interventions Participants were randomly allocated 1:1 to Honevo or control cream (Cetomacrogol), applied twice daily for 8 weeks.Main outcome measures The primary outcome measure was the proportion of participants who had a ≥2 improvement in the 7-point IGA-RSS at week 8 compared to baseline. …”
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Risk factors for the delayed discharge from anesthesia intensive care unit: a single-center retrospective study by Yue Qian, Jing Hao, Wei Zhu, Yan Yang, Zhuan-yun Zhang, Lu-yang Zhou, Xiao-ping Gu, Zheng-liang Ma, Yu-e Sun

“…It is influenced by various risk factors, including age, ASA physical status classification, BMI, preoperative complications, type of surgery and intraoperative blood loss. …”
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