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  1. 3121
  2. 3122

    Immunotherapy in metastatic renal cell carcinoma: Insights from a Dutch nationwide cohort by Hilin Yildirim, Anke Richters, Adriaan D. Bins, Arnoud W. Postema, Maureen J.B. Aarts, Martijn G.H. van Oijen, Patricia J. Zondervan, Katja K.H. Aben

    Published 2025-02-01
    “…Patients diagnosed with synchronous mRCC between 2018 and 2022 were identified from the population-based Netherlands Cancer Registry (n = 2621). The median age was 70 yr and 58% of patients had clear-cell RCC. …”
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  3. 3123

    Individualized drug therapy and survival prediction in ICU patients with acute kidney injury: construction and validation of a nomogram by Rui Yang, Xiaozhe Su, Ziqi Liu, Shuai Shao, Yinhuai Wang, Hao Su, Haiqing He

    Published 2025-02-01
    “…Results This study enrolled 1,208 patients and developed a nomogram incorporating oxygen flow rate, respiratory frequency, continuous venovenous hemodiafiltration status, age, and medication use (including ibuprofen, epinephrine, cefazolin, warfarin, and vasopressin). …”
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  4. 3124

    The Analysis of the Fetal Abdominal Wall and Gastrointestinal Tract Abnormalities in a Single Tertiary Center by Gokhan Bolluk, Suleyman Cemil Oglak, Merih Cetinkaya, Isil Turan Bakirci, Oyhan Demirali, Mehmet Cok, Handan Turhan Karakus, Yasin Onur, Emine Zeynep Yilmaz

    Published 2024-12-01
    “…RESULTS: A total of 67 cases were included in our study with a mean maternal age of 26.4 ± 3.1 years and a median gestational week of first assessment at our center of 22 weeks (12-39 weeks). …”
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  5. 3125

    Internal Dosimetry in Patients Undergoing Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu-[DOTA0-Tyr3] Octerotate: A Single-Center Experience by Elahe Mahmoudi, Mahasti Amoui, Mohammad Reza Deevband, Elahe Pirayesh, Mohammad Reza Asgari, Mehdi Ghorbani

    Published 2025-01-01
    “…The patients had a mean age of 53.5 ± 12 years (ranging from 36 to 70 years) and imaging data were collected at roughly 0 to 2 hours, 4 to 6 hours, 18 to 24 hours, and 36 to 48 hours after the injection of 6401± 628.4 MBq (range of 5500 MBq-7400 MBq) of 177Lu-[DOTA0-Tyr3] octerotate. …”
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  6. 3126

    Exploring healthcare workers’ immunisation behaviour towards COVID-19 vaccines through psychological patterns by Nour El Houda Benkaddour, Sara Ramdani, Hind Khalil, Asmae Lekfif, Naima Abda, Bouchra Oneib, Yassamine Bentata

    Published 2025-01-01
    “…Results: The participants had a median age of 25.5 years (30–34.5) and were predominantly females (68.3%). …”
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  7. 3127

    Reduced functional independence and multimorbidity increases the risk of severe infection among older patients with Omicron: a multicenter retrospective cohort study by Wan Yu, Runnian Huang, Shuning Sun, Li Bu, Xin Chen, Yunhua Di, Shuwu Lin, Qian Li, Yang Yang, Xingyue Ye, Wenxu Wang, Rui Ren, Linze Xi, Ru Zhang, Yi Li, Xin Li, Tianbo Hou, Zibo Ning, Yang Peng, Difei Wang

    Published 2025-02-01
    “…Methods This is a multicentre, retrospective cohort study in northeastern China. Patients aged ≥ 60 years, who were diagnosed with COVID-19 at the time of admission or during hospitalisation. …”
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  8. 3128

    Nutritional intake of micronutrient and macronutrient and type 2 diabetes: machine learning schemes by Mohammad Rashidmayvan, Amin Mansoori, Elahe Derakhshan-Nezhad, Davoud Tanbakuchi, Fatemeh Sangin, Maryam Mohammadi-Bajgiran, Malihehsadat Abedsaeidi, Sara Ghazizadeh, MohammadReza Mohammad Taghizadeh Sarabi, Ali Rezaee, Gordon Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan

    Published 2025-02-01
    “…The study population comprised 9704 individuals aged 35–65 years were enrolled regarding their T2D status, and those with T2D history. 15% of individuals are diabetic and 85% of them are non-diabetic. …”
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  9. 3129

    Gallbladder Wall Thickness as a Non-Invasive Tool for Prediction of Esophageal Varices in Patients with Hepatitis C Related Chronic Liver Disease by Munir Ahmed, Maliha Aziz, Shahzad Riyaz, Mohammad Salih, Rashed Nazir, Muslim Atiq

    Published 2025-02-01
    “…After detailed history, examination laboratory investigations, EGD and ultrasound abdomen were performed. Results: The median age of patients was 54±10.13 years. 89 patients were male (61.4%), and 56 were female (38.6%). 86.9% of patients had EVs Group 1) and 27.6% had no EVs (Group II). …”
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  10. 3130

    Liver cystic echinococcosis: A retrospective study on the demographics and clinical profile of patients managed at a single tertiary institution in central Eastern Cape Province, S... by A Govindasamy, P R Bhattarai, J van Niekerk, J John

    Published 2024-05-01
    “…A total of 56 patients diagnosed with and managed for liver CE were included in the study. The mean age of the patients was 37.5 years. Abdominal pain (n=39; 69.6%) was the most common presenting symptom, and a palpable abdominal mass (n=36; 64.3%) was the predominant presenting sign. …”
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  11. 3131

    Facilitators and barriers to protective eyewear acceptance among Indian farmers: A qualitative study by Gopinath Madheswaran, K Eshwari, Judith Shefali Jathanna, Syed Ibrahim, Krithica Srinivasan, Lakshmi Shinde, Ramesh S Ve, Rashima Asokan, S Saravanan, SB Saranya

    Published 2025-02-01
    “…Results Five focus group discussions were conducted with 31 farmers (mean age 55.8 ± 9.2 years) from three centers. Six themes were identified: occupational hazards while farming, practice patterns for managing occupational hazards, uses of protective eyewear while farming, benefits and challenges of protective eyewear, perceptions about protective eyewear and suggestions for improvement. …”
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  12. 3132
  13. 3133

    Breast cancers with neuroendocrine differentiation: Retrospective case studies series from a single institution based on the 2019 WHO classification by Youngkyung Jeon, Ji-Yeon Kim, Jin Seok Ahn, Young-Hyuck Im, Kyuehee Choi, Sun Young Jeong, Yeji Jung, Jaeyeon Jang, Dae-Ho Choi, Joohyun Hong, Hyo Jung Kim, Soo Youn Cho, Yeon Hee Park

    Published 2024-01-01
    “…Results: A total of 34,370 patients were diagnosed with breast cancer from 1995 to 2022 in SMC, and 14 (0.04 %) patients were diagnosed with breast ‘NENS’: eight NECs, three NETs, and three IBCNST with NED. The patients’ median age was 48.5 years. All patients were treated with curative intent surgery; five patients received neoadjuvant chemotherapy, twelve patients received radiotherapy, six patients received adjuvant chemotherapy, and eight patients received hormone therapy. …”
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  14. 3134

    Relationship between physical literacy and mental health in adolescents: a moderated mediation model with resilience and physical activity as variables by Zhu Shanshan, Tao Ping, Lin Jiabin, Liu Tianzhuo, Lai Xiaomei, Wang Bolei, Dai Leifu, Tang Jianfeng

    Published 2025-02-01
    “…IntroductionPhysical literacy is defined as the motivation, confidence, physical competence, knowledge, and understanding to value and take responsibility for engaging in physical activities for life, and may be associated with higher mental health; however, few studies have explored the processes underlying these positive associations.ObjectivesThe present study aimed to explore the role of resilience in the relationship between physical literacy and mental health, and further examines the mediating role of physical activity.MethodsThis cross-sectional study recruited a sample of 1,022 (aged 10–18 years, Mage = 14.84, SD = 1.79, 44.9% male) Chinese students, grades five to twelve, via physical education courses. …”
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  15. 3135

    Photoaging smartphone app promoting poster campaign to reduce smoking prevalence in secondary schools: the Smokerface Randomized Trial: design and baseline characteristics by Michael Kreuter, Fabian N Fries, Titus J Brinker, Ute Mons, David A Groneberg, Anil Batra, Werner Seeger, Felix Herth, Julia Holzapfel, Tanja G Baudson, Katharina Sies, Lena Jakob, Hannah Maria Baumert, Marlene Heckl, Ana Cirac, Janina L Suhre, Verena Mathes, Hannah Spielmann, Nancy Rigotti, Tobias Raupach, Henning Gall, Claudia Bauer, Pat Marek, Chase H Harrison, Lava Taha, Andreas Owczarek, Felix J Hofmann, Roger Thomas

    Published 2016-11-01
    “…This study aims to evaluate its effectiveness regarding smoking prevalence and students’ attitudes towards smoking.Methods and analysis A randomised controlled trial is conducted with 9851 students of both genders with an average age of 12 years in grades 6 and 7 of 126 secondary schools in Germany. …”
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  16. 3136

    Return to play following craniotomy for non-traumatic brain lesions by Jovanna A. Tracz, Matthew L. Farmer, Mark Hughes, Debraj Mukherjee, Paul M. Brennan

    Published 2025-01-01
    “…From one core patient scenario, 5 further scenarios were developed involving patients of varying age, sport preference, tumor pathology, and craniotomy approach. …”
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  17. 3137

    Abrupt onset or exacerbation of anorexia nervosa following recent infections: a mini-review and a case report with an atypical manifestation of PANS by Lavalle Raffaele, Tournour Cristina, Rubano Serena, Delsedime Nadia, Panero Matteo, Abbate-Daga Giovanni

    Published 2025-02-01
    “…Some cases improved with antibiotics or standard psychiatric treatments, although age, symptom severity, and diagnostic markers like D8/17 varied across studies. …”
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  18. 3138

    RNA editing-based biomarker blood test for the diagnosis of bipolar disorder: protocol of the EDIT-B study by Andrea Miranda-Mendizabal, Diana Vetter, Juan Zambrano, Jeff Zarp, Victor Chavarría, Anna Giménez-Palomo, Meritxell Gonzalez-Campos, Marc Valenti, Lara Walczer Baldinazzo, Sara Siddi, Maurizio Ferrari, Dinah Weissmann, Chantal Henry, Josep Maria Haro, Lars Vedel Kessing, Eduard Vieta

    Published 2025-02-01
    “…The EDIT-B is a blood-based test that combines RNA editing biomarkers and individual data (e.g., age, sex, and tobacco consumption). The clinical validation performance of the EDIT-B will be evaluated using the area under the curve, sensitivity, specificity, positive and negative predictive values, and likelihood ratios. …”
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  19. 3139

    The association between TyG index and cardiovascular mortality is modified by antidiabetic or lipid-lowering agent: a prospective cohort study by Changchang Fang, Nanqin Peng, Jiang Cheng, Xiyu Zhang, Wenli Gu, Zicheng Zhu, Xiaoping Yin, Zhiwei Yan, Jing Zhang, Peng Yu, Xiao Liu

    Published 2025-02-01
    “…Results A total of 5,046 adults (representing 42,753,806 individuals, weighted mean age 61.08 years [SE: 0.24]; 49.35% female) were analyzed. …”
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  20. 3140

    Multimodal treatment with Neoadjuvant chemotherapy for eyelid and periocular sebaceous gland carcinoma: Long-term outcomes by Vijitha S. Vempuluru, Anshika Luthra, Vijay Anand Reddy Palkonda, Swathi Kaliki

    Published 2025-06-01
    “…Observations: Three patients of eSGC with 10-year follow-up were reviewed. The mean age at presentation of eSGC was 50 years (median, 50 years; range, 41–59 years). …”
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