HPLC-MS/MS-Mediated Analysis of the Pharmacokinetics, Bioavailability, and Tissue Distribution of Schisandrol B in Rats by Dahu Liang, Zijing Wu, Yanhao Liu, Chao Li, Xianghong Li, Bin Yang, Haitang Xie, Hua Sun

“…This established method was then successfully applied to investigate the pharmacokinetics, oral bioavailability, and tissue distributions of Schisandrol B in Sprague-Dawley (SD) rats that were intravenously administered 2 mg/kg of Schisandrol B monomer, intragastrically administered Schisandrol B monomer (10 mg/kg), or intragastrically administered 6 mL/kg SCE (equivalent to 15 mg/kg Schisandrol B monomer). The oral absolute bioavailability of Schisandrol B following intragastric Schisandrol B monomer and SCE administration was approximately 18.73% and 68.12%, respectively. …”
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Transcriptome and DNA methylation analysis of the goat pineal gland during puberty by Bochao Zhang, Genbao Zhu, Jianling Wu, Huihui Xie, Jiankun Cui, Wei Qian, Qing Yi, Fuqiang Pan, Fugui Fang, Yinghui Ling, Yunhai Zhang, Yunsheng Li, Ya Liu

“…Genes with a P-value less than 0.05 and an absolute log2 fold change greater than 0 were considered differentially expressed genes. …”
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Prediction of lower-limb isokinetic strength from functional fitness tests in older adults: A 550-participant cross-sectional study by Carlos Babiloni-López, Pablo Jiménez-Martínez, Carlos Alix-Fages, Ángel Saez-Berlanga, Álvaro Juesas, Pedro Gargallo, Javier Gene-Morales, Juan C. Colado

“…Purpose: This study aimed to explore the association and prediction of hip abduction-adduction and knee flexion-extension isokinetic absolute and relative strength and power at 60°/s and 180°/s from functional tests performance (i.e., Up-and-Go Test [seconds], 30-Second Chair Stand Test [repetitions and relative and allometric power], 30-Second Arm Curl Test [repetitions], and 6-Minute Walk Test [meters]) in older adults. …”
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Impact of Systolic Blood Pressure Trajectories and Variability on Unexplained Early Neurological Deterioration Post‐Endovascular Treatment in Acute Ischemic Stroke Patients by Xuxuan Gao, Qiheng Wu, Yu Ma, Yueran Ren, Jiaying Chen, Xiaofei Lin, Lianghao Ye, Wei Song, Jiajia Zhu, Jia Yin

“…Therefore, comprehensive post‐EVT blood pressure management should address both absolute BP levels and BPV, with particular emphasis on nighttime monitoring, to optimize early neurological recovery.…”
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Circulating C19MC MicroRNAs in Preeclampsia, Gestational Hypertension, and Fetal Growth Restriction by Ilona Hromadnikova, Katerina Kotlabova, Marketa Ondrackova, Andrea Kestlerova, Veronika Novotna, Lucie Hympanova, Jindrich Doucha, Ladislav Krofta

“…We examined the correlation between plasmatic concentrations and expression levels of microRNAs and the severity of the disease with respect to clinical signs, requirements for the delivery, and Doppler ultrasound parameters. Using absolute and relative quantification approaches, increased extracellular C19MC microRNA levels (miR-516-5p, P=0.037, P=0.009; miR-517*, P=0.033, P=0.043; miR-520a*, P=0.001, P=0.009; miR-525, P=0.026, P=0.01; miR-526a, P=0.03, P=0.035) were detected in patients with preeclampsia. …”
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Power of emperor in Russian legal discourse of second half of 19th– early 20th centuries: justification and options for interpretation by I. G. Adoneva, Yu. V. Druzhinina

“…This kind of theoretical constructs became a compromise between the preservation of absolute monarchical power and the worldview of those jurists who shared liberal values…”
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Heightened demand for mental health information resources during the SARS-CoV-2 pandemic in Germany: A retrospective longitudinal analysis of helpline calls by Jil Zippelius, Simon Schreynemackers, Ulrich Hegerl, Hanna Reich

“…Furthermore, rolling back cross-validation was employed to iteratively assess mean absolute errors over one-month periods during the pre-phase, the SARS-CoV-2-phase and the post-phase to explore variations in forecast quality across these timeframes. …”
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A Data-Driven Approach to Engineering Instruction: Exploring Learning Styles, Study Habits, and Machine Learning by Lauren Genith Isaza Dominguez, Antonio Robles-Gomez, Rafael Pastor-Vargas

“…Voting Ensemble was found to be the strongest model, explaining 83% of the variance in final exam scores, with a mean absolute error of 3.18. Our findings suggest that, while learning style alignment improves short-term engagement and comprehension, effective study habits and time management play a more important role in long-term academic success.…”
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The Association between the Frequency of Rhegmatogenous Retinal Detachment and Atmospheric Temperature by Dong Yoon Kim, Hyeseong Hwang, Jae-Hyung Kim, Byung Gil Moon, Sung Min Hyung, Jin Young Kim, Ju Byung Chae

“…This showed that a wide daily range of temperature, rather than the absolute value of the temperature, is associated with the occurrence of RRD. …”
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Phenotype of Peripheral NK Cells in Latent, Active, and Meningeal Tuberculosis by José Alberto Choreño-Parra, Luis Armando Jiménez-Álvarez, Ellis Daniela Maldonado-Díaz, Graciela Cárdenas, Luis Alejandro Fernández-Lopez, José Luis Soto-Hernandez, Marcela Muñoz-Torrico, Gustavo Ramírez-Martínez, Alfredo Cruz-Lagunas, Armando Vega-López, María Lilia Domínguez-López, Carlos Sánchez-Garibay, Parménides Guadarrama-Ortíz, Silvia Giono, Luis Antonio Jiménez-Zamudio, Shabaana A. Khader, Ethel A. García-Latorre, Citlaltepetl Salinas-Lara, Joaquín Zúñiga

“…We found that NK cells from TBM patients showed lower absolute frequencies, higher CD69 expression, and poor expansion of the CD45RO+ memory-like subpopulation upon Mtb exposure in vitro compared to LTBI individuals. …”
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Hybrid parking space prediction model: integrating ARIMA, Long short-term memory (LSTM), and backpropagation neural network (BPNN) for smart city development by Anchal Dahiya, Pooja Mittal, Yogesh Kumar Sharma, Umesh Kumar Lilhore, Sarita Simaiya, Mohd Anul Haq, Mohammed A. Aleisa, Abdullah Alenizi

“…The proposed hybrid model achieves the minimum mean squared error (MSE), mean absolute error (MAE), and root mean squared error (RMSE) values of 0.32, 0.48, and 0.56, respectively. …”
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Machine learning-based prediction of in-hospital mortality for critically ill patients with sepsis-associated acute kidney injury by Tianyun Gao, Zhiqiang Nong, Yuzhen Luo, Manqiu Mo, Zhaoyan Chen, Zhenhua Yang, Ling Pan

“…According to the SHAP plots, old age, low Glasgow Coma Scale (GCS) score, high AKI stage, reduced urine output, high Simplified Acute Physiology Score (SAPS II), high respiratory rate, low temperature, low absolute lymphocyte count, high creatinine level, dysnatremia, and low body mass index (BMI) increased the risk of poor prognosis.Conclusions The RF model developed in this study is a good predictor of in-hospital mortality for patients with SA-AKI in the intensive care unit (ICU), which may have potential applications in mortality prediction.…”
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Premorbid predictors of death at initial presentation of coronary heart disease in the Women's Health Initiative study by Ming-Li Chen, Jin Li, Kruthika R. Iyer, Catherine Tcheandjieu, Shirin Jimenez, Elias Levy Itshak Salfati, Liana C. Del Gobbo, Marcia L Stefanick, Manisha Desai, Xiaonan Xue, Themistocles L Assimes

“…A significant dose-response effect was observed for both physical activity and smoking and the reduction in absolute risk of presenting with fatal CHD associated with a healthy lifestyle was roughly equivalent to the difference in risk observed among women separated in age by approximately 10 years. …”
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Increased indexed proximal aortic diameter is a predictor of poor prognosis in maintenance hemodialysis patients by Junwei Xu, Wenyi Tang, Lizheng Song, Yuxi Huang, Li Xiao, Fangyuan Cheng, Qianglin Guan, Mei Xu, Chuoxin Ma, Jian Chen, Jianting Ke

“…Background Recent studies have shown that the baseline values of absolute aortic root diameter (ARD) and indexed diameter are associated with all-cause mortality and cardiovascular events in the general population, even in the absence of aneurysmal aortic disease. …”
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Comparative Proteome Analysis of Epicardial and Subcutaneous Adipose Tissues from Patients with or without Coronary Artery Disease by Yu xing Zhao, Hui juan Zhu, Hui Pan, Xue mei Liu, Lin jie Wang, Hong bo Yang, Nai shi Li, Feng ying Gong, Wei Sun, Yong Zeng

“…Isobaric Tagging for Relative and Absolute Quantitation (iTRAQ) analysis combined with liquid chromatography tandem-mass spectrometry (LC-MS/MS) was performed to identify the differentially expressed proteins. …”
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Long-Term Outcomes Following Inguinal Hernia Repair With Mesh Performed by Medical Doctors and Surgeons in Ghana by Jessica H. Beard, MD, Michael Ohene-Yeboah, MBChB, Emmanuel S. Kasu, MBChB, Nelson Affram, MBChB, Stephen Tabiri, MD, Joachim K. A. Amoako, MBChB, Francis A. Abantanga, MD, Jenny Löfgren, MD

“…The overall 5-year recurrence rate was 4.7% (n = 8). The absolute difference in recurrence rate between the medical doctor group (2 [2.3%]) and the surgeon group (6 [7.3%]) was −5.0 (1-tailed 95% confidence interval, −10.5; P = 0.06), demonstrating noninferiority of the medical doctors. …”
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Natremia Significantly Influences the Clinical Outcomes in Patients with Severe Traumatic Brain Injury by Bharti Sharma, Winston Jiang, Munirah M. Hasan, George Agriantonis, Navin D. Bhatia, Zahra Shafaee, Kate Twelker, Jennifer Whittington

“…Moreover, variability in serum SLs is independently associated with mortality throughout the hospital stay, irrespective of the absolute serum sodium concentration.…”
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Clinical characteristics and usage of statins in patients with stable ischemic heart disease referred for angiography or coronary artery bypass grafting by I.V. Shklianka, O.J. Zharinov, К.O. Mikhaliev, O.A. Epanchintseva

“…The studied patients’ cohort was characterized by earlier coronary events, signs of the peripheral artery atherosclerosis and other absolute indications for treatment with statins in vast majority of cases. …”
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Effects of Whey Protein Concentrate on the Bioaccessibility and Microstructure of 5-Methyltetrahydrocalcium Folate in Simulated Digestive Environment in Vitro by Yusong ZHANG, Weiran CUI, Zhenyue TANG, Hongyu BAI, Meili SHAO

“…The results of particle size and zeta potential showed that the WPC-5-MTHF group had smaller particle size, larger absolute value of zeta potential, and the structural changes of WPC-5-MTHF would cause changes in digestibility characteristics. …”
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Genetic aspects of potato resistance to phytophthorosis by T. S. Frolova, V. A. Cherenko, O. I. Sinitsyna, A. V. Kochetov

“…Both types of traits are important for potato breeding: quantitative resistance due to R-genes is quickly overcome by the pathogen, while quantitative trait loci make it possible to create varieties with almost absolute resistance due to the pyramid of effective genes. …”
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