Spectrum, Pattern, and Clinical Outcomes of Adult Emergency Department Admissions in Selected Hospitals of Western Ethiopia: A Hospital-Based Prospective Study by Ashenafi Habte Woyessa, Birhanu Yadecha Dibaba, Getahun Fetensa Hirko, Thanasekaran Palanichamy

“…There has been a steady rise in the absolute number of emergency room admissions over the last few decades. …”
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COMBINED TREATMENT OF LOCALLY-ADVANCED BLADDER CANCER by I. V. Chernyshev, Y. V. Samsonov, D. V. Perepechin, A. M. Ulbashev

“…In 2013, in Russia, the absolute number of patients with first-ever diagnosis of bladder cancer was 12 992 people. …”
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Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Nondialysis Chronic Kidney Patients by Gysllene M. C. Brito, Andrea M. M. Fontenele, Erika Cristina R. L. Carneiro, Iara Antonia L. Nogueira, Tamires B. Cavalcante, André A. M. Vale, Sally Cristina M. Monteiro, Natalino Salgado Filho

“…NLR and PLR were calculated based on the absolute number of neutrophils, lymphocytes, and platelets and were compared between them and with hs-CRP. …”
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Association between Glycemic Control and Clinic Attendance in Emerging Adults with Type 1 Diabetes: A Tertiary Center Experience by Eldad Fisher, Liora Lazar, Shlomit Shalitin, Michal Yackobovitch-Gavan, Liat de Vries, Tal Oron, Ariel Tenenbaum, Moshe Phillip, Yael Lebenthal

“…In emerging adults with T1D during the ongoing stable phase of diabetes management, higher attendance rate, rather than absolute number of clinic visits, was associated with the attainment of glycemic targets.…”
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A prognostic signature of Glutathione metabolism-associated long non-coding RNAs for lung adenocarcinoma with immune microenvironment insights by Junxi Hu, Junxi Hu, Shuyu Tian, Shuyu Tian, Qingwen Liu, Qingwen Liu, Jiaqi Hou, Jiaqi Hou, Jun wu, Jun wu, Xiaolin Wang, Xiaolin Wang, Yusheng Shu, Yusheng Shu

“…A prognostic model was built with Cox and Least Absolute Shrinkage and Selection Operator (LASSO) methods and validated by Kaplan-Meier analysis, Receiver Operating Characteristic (ROC) curves, and Principal Component Analysis (PCA). …”
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Ground-based Characterization of (98943) Torifune 2001 CC21, the Target of the Hayabusa2# Space Mission by Marcel M. Popescu, Eri Tatsumi, Javier Licandro, Miguel R. Alarcon, Javier Rodríguez Rodríguez, Miquel Serra-Ricart, Julia de León, Joaquín Fernandez Martin, David Morate, Gabriel N. Simion, Bogdan Alexandru Dumitru, Daniel Nicolae Berteşteanu, George Pantelimon Prodan, Masatoshi Hirabayashi

“…We determined its rotation period P  = 5.021516 ± 0.000106 hr and its absolute magnitude H = 18.78  ±  0.14. The large number of light curves allows us to estimate its axis ratio, its convex shape, and its pole orientation, λ  = 301 ^∘  ± 35 ^∘ , $\beta =8{9}_{-6}^{+1^\circ }$ , and ϵ  = 5 ^∘  ± 3 ^∘ , respectively, which indicate a prograde rotation. …”
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Predicting the risk of heart failure after acute myocardial infarction using an interpretable machine learning model by Qingqing Lin, Qingqing Lin, Wenxiang Zhao, Wenxiang Zhao, Hailin Zhang, Hailin Zhang, Wenhao Chen, Sheng Lian, Qinyun Ruan, Qinyun Ruan, Zhaoyang Qu, Zhaoyang Qu, Yimin Lin, Yimin Lin, Dajun Chai, Dajun Chai, Dajun Chai, Dajun Chai, Xiaoyan Lin, Xiaoyan Lin, Xiaoyan Lin, Xiaoyan Lin

“…For developing a predictive model for HF risk in AMI patients, the least absolute shrinkage and selection operator (LASSO) Regression was used to feature selection, and four ML algorithms including Random Forest (RF), Extreme Gradient Boost (XGBoost), Support Vector Machine (SVM), and Logistic Regression (LR) were employed to develop the model on the training set. …”
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Development and external validation of a dynamic nomogram for predicting the risk of functional outcome after 90 days in patients with acute intracerebral hemorrhage by Shaojie Li, Hongjian Li, Jiani Chen, Baofang Wu, Jiayin Wang, Chaocan Hong, Changhu Yan, Weizhi Qiu, Yasong Li, Hongzhi Gao

“…In this study, adverse outcomes were defined as a Modified Rankin Scale (mRS) score of 3–6 at 90 days post-ICH onset, as assessed during follow-up. Later, least absolute shrinkage and selection operator (LASSO) regression and multifactorial logistic regression were used to screen the variables and construct a nomogram. …”
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Characteristic of the active substance of the Saccharomyces cerevisiae preparation having radioprotective properties by G. S. Ritter, V. P. Nikolin, N. A. Popova, A. S. Proskurina, P. E. Kisaretova, O. S. Taranov, T. D. Dubatolova, E. V. Dolgova, E. A. Potter, S. S. Kirikovich, Y. R. Efremov, S. I. Bayborodin, M. V. Romanenko, M. I. Meschaninova, A. G. Venyaminova, N. A. Kolchanov, S. S. Bogachev

“…Injection of 160 μg double-stranded RNA protects 100 % of the experimental animals from an absolutely lethal dose of gamma radiation, 9.4 Gy. It was established that the radioprotective effect of double-stranded RNA does not depend on sequence, but depends on its double-stranded form and the presence of “open” ends of the molecule. …”
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The clinical implication of CD45RA+ naïve T cells and CD45RO+ memory T cells in advanced pancreatic cancer: a proxy for tumor biology and outcome prediction by Junjie Hang, Junjie Huang, Siyuan Zhou, Lixia Wu, Yingwei Zhu, Lina Zhu, Hanyu Zhou, Kequn Xu, Hua Jiang, Xuguang Yang

“…CD4+ naïve/memory ratio showed close correlations with hemoglobin, red blood cell (RBC), absolute neutrophil count (ANC) and platelet while CD8+ naïve/memory ratio was correlated with hemoglobin, RBC and CEA. …”
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Identification and preliminary validation of biomarkers associated with mitochondrial and programmed cell death in pre-eclampsia by Rong Lin, Rong Lin, XiaoYing Weng, XiaoYing Weng, Liang Lin, Liang Lin, XuYang Hu, XuYang Hu, ZhiYan Liu, ZhiYan Liu, Jing Zheng, Jing Zheng, FenFang Shen, FenFang Shen, Rui Li, Rui Li

“…Hub genes were determined using support vector machine, least absolute shrinkage and selection operator, and Boruta based on consistent expression profiles. …”
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Associations between brominated flame retardants exposure and non-alcoholic fatty liver disease: Mediation analysis in the NHANES by Yulan Cheng, Jingyi Su, Xiangdong Wang, Ruiyao Huang, Zixuan Zhao, Kai Tian, Tianxiang Gu, Xiaoke Wang, Lin Chen, Xinyuan Zhao

“…Additionally, mediation analysis showed that absolute neutrophil cell count (ANC) and lymphocyte count (LC) (inflammation markers) have significantly mediated influences on the correlations of PBB153, PBDE85, and PBDE28 with N AFLD risk. …”
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PDL1 inhibitors may be associated with a lower risk of allograft rejection than PD1 and CTLA4 inhibitors: analysis of the WHO pharmacovigilance database by Alexandre O. Gérard, Alexandre O. Gérard, Alexandre O. Gérard, Diane Merino, Diane Merino, Jonathan Benzaquen, Alexandre Destere, Delphine Borchiellini, Clément Gosset, Clément Gosset, Fanny Rocher, Marine Andreani, Charles-Hugo Marquette, Henri Montaudié, Henri Montaudié, Milou-Daniel Drici, Antoine Sicard, Antoine Sicard

“…ICI may trigger allograft rejection, but the absolute risk of AR between the different ICI classes remains to be defined.MethodsVigiBase® (WHO’s pharmacovigilance database) was queried for reports of AR involving CTLA4, PD1, or PDL1 inhibitors. …”
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Temporal Trends in Mortality and Hospitalization Risk in Patients With Heart Failure According to the Hospital Frailty Risk Score by Noor K. Abassi, Nina Nouhravesh, Mariam Elmegaard, Marte Austreim, Deewa Zahir, Caroline Hartwell Garred, Jawad H. Butt, Camilla Fuchs Andersen, Jarl E. Strange, Caroline Sindet‐Pedersen, Daniel M. Christensen, Emil Fosbøl, Charlotte Andersson, Lars Køber, Morten Schou

“…The proportion of moderately frail patients increased from 13.2% to 24.9%. Five‐year absolute risks of all‐cause mortality, HF hospitalization, and non‐HF hospitalization were calculated using the Kaplan‐Meier and Aalen‐Johansen estimators. …”
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Impaction bone grafting for acetabular bone defects replacement in revision hip arthroplasty: biomechanical aspects by Vadim N. Golnik, Natalia V. Fedorova, Alexey Y. Larichkin, Svetlana V. Boyko, Andrey A. Panchenko, Alexandr M. Kosinov, Vladimir A. Peleganchuk, Vitaliy V. Pavlov

“…The change in the position of the rotation center and acetabular component in the absence of a radiolucent line is not an absolute sign of loosening.…”
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Development and validation of a nomogram for predicting lung cancer based on acoustic–clinical features by Zhou Lu, Zhou Lu, Jiaojiao Sha, Xunxia Zhu, Xiaoyong Shen, Xiaoyu Chen, Xin Tan, Rouyan Pan, Shuyi Zhang, Shi Liu, Tao Jiang, Jiatuo Xu

“…First, acoustic features were extracted from all participants, and optimal features were selected by least absolute shrinkage and selection operator (LASSO) regression. …”
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Association of a multiplex immune marker panel with incident cognitive impairment and dementia: The Northern Manhattan Study by Mohammad Abdurrehman Sheikh, Michelle P. Moon, Clinton B. Wright, Jose Gutierrez, Minghua Liu, Tatjana Rundek, Ken Cheung, Mady Hornig, Mitchell S.V. Elkind

“…Immune markers were assessed using a multiplex immunoassay on plasma samples collected at the time of the first neuropsychological test. Least absolute shrinkage and selection operator (LASSO) techniques were employed to yield a panel of immune markers linearly related to the outcome of dementia/MCI vs. no cognitive impairment. …”
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Burden of NASH related liver cancer from 1990 to 2021 at the global, regional, and national levels by Shuang Li, Shuang Li, Shuangjiang Li, Linjing Guan, Mingjuan Li, Jiahui Zhao, Min Wu, Qiuyun Li, Hui Li, Guoqing Ouyang, Guangdong Pan, Guangdong Pan

“…East Asia, South Asia, and Southeast Asia reported the highest absolute case numbers, while Western, Southern, and Eastern Sub-Saharan Africa exhibited the highest ASRs. …”
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DFT and molecular docking analyses of the effects of solvent polarity and temperature on the structural, electronic, and thermodynamic properties of p-coumaric acid: Insights for a... by Umer Sherefedin, Abebe Belay, Kusse Gudishe, Alemu Kebede, Alemayehu Getahun Kumela, Tadesse Lemma Wakjira, Dereje Gelanu, Tesfaye Feyise, Jebel Haji Mahamud, Abdulkerim Abdela, Kebede Shankute Gizew

“…Furthermore, the results indicated that solvent polarity caused variations in the Fourier transform infrared (FTIR) spectra, absolute and solvation energies, dipole moment, and HOMO–LUMO gap. …”
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Machine learning-based identification and validation of amino acid metabolism related genes as novel biomarkers in chronic kidney disease by Guoqing Zhang, Hongyan Luo, Xiaohua Lu, Yonghua Liu, Mei Wang, Bo Li, Haixia Lu, Yali Zheng

“…Methods: We filtered the key genes associated with AA metabolism based on the least absolute shrinkage and selection operator (LASSO) and SVM algorithm. …”
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