Editorial: Clinical trial design and development in neonatal and perinatal medicine by Mohamed E. Abdel-Latif, Mohamed E. Abdel-Latif, Mohamed E. Abdel-Latif, Yogavijayan Kandasamy, Yogavijayan Kandasamy, Yogavijayan Kandasamy, Sabita Uthaya, Sabita Uthaya, Dirk Bassler, Dirk Bassler, Jonathan M. Davis, Jonathan M. Davis

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Sugar Antennae for Guidance Signals: Syndecans and Glypicans Integrate Directional Cues for Navigating Neurons by Christa Rhiner, Michael O. Hengartner

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Drivers of methane-cycling archaeal abundances, community structure, and catabolic pathways in continental margin sediments by Longhui Deng, Longhui Deng, Damian Bölsterli, Clemens Glombitza, Bo Barker Jørgensen, Hans Røy, Mark Alexander Lever, Mark Alexander Lever

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Sex differences in the time trends of sepsis biomarkers following polytrauma by Cédric Niggli, Philipp Vetter, Jan Hambrecht, Hans-Christoph Pape, Ladislav Mica

“…This retrospective cohort study at University Hospital Zurich included polytrauma patients aged ≥ 16 years with an Injury Severity Score (ISS) ≥ 16 who developed sepsis within 31 days of admission. …”
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Distributed representations enable robust multi-timescale symbolic computation in neuromorphic hardware by Madison Cotteret, Hugh Greatorex, Alpha Renner, Junren Chen, Emre Neftci, Huaqiang Wu, Giacomo Indiveri, Martin Ziegler, Elisabetta Chicca

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Don’t mind the gap: reframing the Perren strain rule for fracture healing using insights from virtual mechanical testing by Maham Tanveer, Karina Klein, Brigitte von Rechenberg, Salim Darwiche, Hannah L. Dailey

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Explaining the γγ + X excesses at ≈151.5 GeV via the Drell-Yan production of a Higgs triplet by Saiyad Ashanujjaman, Sumit Banik, Guglielmo Coloretti, Andreas Crivellin, Siddharth P. Maharathy, Bruce Mellado

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The microvelocity of money in Ethereum by Francesco Maria De Collibus, Carlo Campajola, Claudio J. Tessone

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Relapsing Depression in Paramedian Thalamic Infarctions by R. W. Baumgartner, T. Landis, M. Regard

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Multi-objective design of multi-material truss lattices utilizing graph neural networks by Ramón Frey, Michael R. Tucker, Mohamadreza Afrasiabi, Markus Bambach

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Regulatory Role of CD4+ T Cells in Myocarditis by Daria Vdovenko, Urs Eriksson

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Phospho-seq: integrated, multi-modal profiling of intracellular protein dynamics in single cells by John D. Blair, Austin Hartman, Fides Zenk, Philipp Wahle, Giovanna Brancati, Carol Dalgarno, Barbara Treutlein, Rahul Satija

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Long-Term Follow-Up in Children with Anisocoria: Cocaine Test Results and Patient Outcome by Fabienne C. Fierz, Christina Gerth-Kahlert

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Animal Experimentation in Basic Research – Current Discussion and Implications of the Latest Jurisprudence in Switzerland by Nicole Lüthi, Katerina Stoykova, Margot Michel

“…This article takes a recent decision by the Zurich Administrative Court on a severely harmful animal experiment as an impetus to analyze and contextualize recent Swiss jurisprudence, and to clarify its implications for basic research. …”
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Understanding the distributional effects of recurrent floods in the Philippines by Inga J. Sauer, Brian Walsh, Katja Frieler, David N. Bresch, Christian Otto

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Influence of Vanadium 4+ and 5+ Ions on the Differentiation and Activation of Human Osteoclasts by Matthias A. König, Oliver P. Gautschi, Hans-Peter Simmen, Luis Filgueira, Dieter Cadosch

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Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot study by Isabell Anna Just, Denis Fries, Sina Loewe, Volkmar Falk, Nikola Cesarovic, Frank Edelmann, Anna Feuerstein, Florian L. Haufe, Michele Xiloyannis, Robert Riener, Felix Schoenrath

“…Abstract Aims The aim of this pilot study was to investigate the safety, feasibility, tolerability, and acceptability of an assisted mobilization of advanced heart failure patients, using a lightweight, exoskeleton‐type robot (Myosuit, MyoSwiss AG, Zurich, Switzerland). Methods and results Twenty patients in functional NYHA class III performed activities of daily life (ADL, n = 10) or participated in a single, standardized, 60 min rehabilitation exercise unit (REU, n = 10) with and without the Myosuit. …”
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Prolonged Storage of Bound Organic Carbon in Wetland but Not Upland Soils: A 13C and 14C Perspective by Tian Ma, Yiyun Wang, Guohua Dai, Juan Jia, Zongguang Liu, Yufu Jia, Simin Wang, Erxiong Zhu, Xinying Zhang, Negar Haghipour, Lukas Wacker, Bingrui Jia, Jin‐Sheng He, Hailong Zhang, Meixun Zhao, Timothy I. Eglinton, Xiaojuan Feng

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Calcitonin Gene-Related Peptide (Cgrp), Adrenomedullin (Am), Amylin, And Calcitonin (Ct) Receptors And Overlapping Biological Actions by J.A. Fischer, W. Born, R. Muff

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Four decades of phenology in an alpine amphibian: trends, stasis, and climatic drivers by Lenzi, Omar, Grossenbacher, Kurt, Zumbach, Silvia, Lüscher, Beatrice, Althaus, Sarah, Schmocker, Daniela, Recher, Helmut, Thoma, Marco, Ozgul, Arpat, Schmidt, Benedikt R.

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