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    Functional Remediation Improves Serum BDNF and TrkB Levels in Euthymic Patients with Bipolar Disorder: A Randomized Trial Study by Li R, Li J, Ji SS, Li D, Chu L, Zhang J, Sun X, Luo X, Zhang Y

    Published 2025-01-01
    “…Ru Li,1,* Jiaxin Li,1,* Shiyi Suzy Ji,2 Dazhi Li,1 Lijun Chu,1 Jian Zhang,1 Xia Sun,1 Xingguang Luo,3 Yong Zhang1 1Unit of Bipolar Disorder, Tianjin Anding Hospital, Tianjin, People’s Republic of China; 2Department of Counseling and Clinical Psychology, Teachers College, Columbia University, NY, New York, USA; 3Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA*These authors contributed equally to this workCorrespondence: Yong Zhang, Unit of Bipolar Disorder, Tianjin Anding Hospital, 13 Liulin Road, Hexi District, Tianjin, 300222, People’s Republic of China, Tel/Fax +86 22 8818 8258, Email zhangyong@tjmhc.comPurpose: We aimed to verify the impact of functional remediation (FR) on serum brain-derived neurotrophic factor (BDNF) and tyrosine kinase receptor B (TrkB) levels, to explore the biomechanism of FR intervention in patients with euthymic bipolar disorder (BD).Patients and Methods: This is a randomized controlled, 12-week intervention study with participants randomized into the FR group (n=39) and the treatment as usual group (TAU, n=42) at the 1∶1 ratio. 17-Hamilton Depression Rating Scale-17 (HDRS-17), Young Mania Rating Scale (YMRS), and Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery (MCCB) were used to assess affective symptoms and cognitive functioning both at baseline and week 12, respectively. …”
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    Mtazamo wa Umma Katika Ulazimishaji wa Ufundishaji wa Lug Hay a Kiswahili Nchini Uganda Tukilenga Wila Yaya Kasese ka Tika Tarafa ya Bwera. by Biira, Felistus

    Published 2023
    “…Sura ya pili iliundwa na maandishi ya wataalamu pamoja na watafiti wengine, maoni haya ni yale ambayo yanahusiana na mada ya utafiti huu.Hata hivyo, maoni hayo yalikuwa na mchango mkubwa katika utafiti huu, ila 'yalikuwa na pengo zilizozibwa katika utafiti huu jvetu uliohusu mtazamo wa umma katika ulazimishaji wa ufundishaji wa lugha ya Kiswahili nchiniUganda tukilenga wilaya ya Kasese katika tarafa ya Bwera. …”
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