Les aqueducs de Lyon à l’approche de la ville antique by Emmanuelle Dumas

“…The siphon’s arrival point may be located around ten metres further downstream than had previously been envisaged, based on a rereading of the remains found at its western end. At its eastern end, little can be discovered. …”
Get full text

Global comparison of the economic costs of coronary heart disease: a systematic review and meta-analysis by Lan Gao, Susan Brumby, Crystal Man Ying Lee, George Mnatzaganian, Suzanne Robinson, Helen Brown, Rachel Huxley, Anna Peeters, Dan Xu, James Boyd, Sean Randall, Adrienne O’Neil, Sangita Shakya, Sarah Gauci, Anita Shrestha, James Lucas

Get full text

Spinal cord demyelination predicts neurological deterioration in patients with mild degenerative cervical myelopathy by Jefferson R Wilson, David Anderson, Stephan Duplessis, Julien Cohen-Adad, David W Cadotte, Nathan Evaniew, Jacques Bouchard, Michael Craig, Abdul Al-Shawwa, Kalum Ost, Steve Casha, W Bradley Jacobs, Saswati Tripathy, Peter Lewkonia, Fred Nicholls, Alex Soroceanu, Ganesh Swamy, Kenneth C Thomas, Michael MH Yang, Nicholas Dea

Get full text

ATP1B3 may promote glioma proliferation and migration through MAPK/NF-KB signaling pathway by Qikang Yan, Quan Sun, Yan Feng, Qingyun Hu, Jinling Zhu

“…The knockdown efficiency was assessed by Western Blotting (WB) and RT-qPCR. Following ATP1B3 knockdown, the ability of glioma cells to proliferate, migrate, and invade was identified using the Transwell assay and CCK-8. …”
Get full text

Elucidating the effects of manganese on the growth and cadmium accumulation of OsNRAMP5 mutant rice by Xian’an Yu, Qiuqin Zhou, Xin-Yuan Huang, Mingxue Chen, Jiawen Zhou, Tong Zhou, Pengjie Hu, Xia Pan, Miaomiao Cheng, Yongming Luo, Peter Christie, Longhua Wu

Get full text

Identification and Mass Spectrometric Fragmentation Pathways of Chemical Components in the Traditional Chinese Medicine Formula of Jiuwei Decoction by Jia-yu ZHAO, Yue-guang LYU, Tong XIN, Qian-qian GUO, Wen-ying ZHANG, Jin-hong LI, Hong-yu XUE, Qiang MA

“…Traditional Chinese medicine (TCM), both a longstanding medical practice in Asia and an increasingly utilized supplement or alternative medicine in Western countries, has become a focal point within the life sciences in recent years. …”
Get full text

Exosome‐derived long non‐coding RNA AC010789.1 modified by FTO and hnRNPA2B1 accelerates growth of hair follicle stem cells against androgen alopecia by activating S100A8/Wnt/β‐cat... by Shaojun Chu, Lingling Jia, Yulong Li, Jiachao Xiong, Yulin Sun, Qin Zhou, Dexiang Du, Zihan Li, Xin Huang, Hua Jiang, Baojin Wu, Yufei Li

“…The specific binding between AC010789.1 and FTO mediated m6A modification or the effect of AC010789.1 on hnRNPA2B1, S100A8 and Wnt/β‐catenin signaling expression was confirmed by bioinformatic analysis, RIP, RNA pull‐down and Western blot assay. The effects of Exosome‐loaded AC010789.1 prompted HFSCs proliferation and hair follicle regeneration were confirmed in hairless mice. …”
Get full text

A simple staging system using biomarkers for wild‐type transthyretin amyloid cardiomyopathy in Japan by Naoya Nakashima, Seiji Takashio, Mami Morioka, Masato Nishi, Toshihiro Yamada, Kyoko Hirakawa, Masanobu Ishii, Noriaki Tabata, Kenshi Yamanaga, Koichiro Fujisue, Daisuke Sueta, Hisanori Kanazawa, Tadashi Hoshiyama, Shinsuke Hanatani, Satoshi Araki, Hiroki Usuku, Eiichiro Yamamoto, Mitsuharu Ueda, Kenichi Matsushita, Kenichi Tsujita

“…However, these studies were mainly conducted in Western countries, and their usefulness for the Japanese population is unclear. …”
Get full text

Sex differences in the peripheral levels of cytokines during 12-month antipsychotic treatment in a drug-naïve schizophrenia spectrum cohort by I. Ratke, A. Torsvik, C.A. Bartz-Johannessen, F. Fathian, I. Joa, S.M. Klæbo Reitan, E.M. Løberg, M. Rettenbacher, S. Skrede, V.M. Steen, E. Johnsen, R.A. Kroken

“…Funding: The Research Council of Norway, the Western Norway Regional Health Trust, and the participating hospitals and universities provided funding for this study.…”
Get full text

Electroacupuncture Relieves Suppression of Autophagy in Interstitial Cells of Cajal of Diabetic Gastroparesis Rats by Xing Wei, Yaping Lin, Dongfeng Zhao, Xiaojuan Xiao, Qiao Chen, Siyi Chen, Yan Peng

“…The expression of LC3 protein and P62 protein was measured by Western blot. When ICCs were transfected with GFP-RFP-LC3 plasmid, autophagy flux was observed by laser scanning confocal microscope. …”
Get full text

Analysis of the spatiotemporal dynamics of vascular injury and regeneration following experimental Spinal Cord Injury by Christian J. Entenmann, Emily J. von Bronewski, Lilly Waldmann, Lea Meyer, Katharina Kersting, Laurens T. Roolfs, Lasse M. Schleker, Melina Nieminen-Kelhä, Irina Kremenetskaia, Frank L. Heppner, Michael G. Fehlings, Peter Vajkoczy, Vanessa Hubertus

Get full text

Investigating heterogeneity across autism, ADHD, and typical development using measures of cortical thickness, surface area, cortical/subcortical volume, and structural covariance by Younes Sadat-Nejad, Younes Sadat-Nejad, Marlee M. Vandewouw, Marlee M. Vandewouw, R. Cardy, J. Lerch, J. Lerch, J. Lerch, M. J. Taylor, M. J. Taylor, A. Iaboni, C. Hammill, B. Syed, J. A. Brian, J. A. Brian, E. Kelley, E. Kelley, E. Kelley, M. Ayub, J. Crosbie, J. Crosbie, R. Schachar, R. Schachar, S. Georgiades, R. Nicolson, E. Anagnostou, E. Anagnostou, A. Kushki, A. Kushki

Get full text

Potential of long-term satellite observations and reanalysis products for characterising soil drying: trends and drought events by M. Hirschi, P. Stradiotti, B. Crezee, B. Crezee, W. Dorigo, S. I. Seneviratne

“…Geographically, drying is localised to parts of Europe and the Mediterranean; the Black Sea–Caspian Sea and Central Asian region; Siberia; parts of the western USA and the Canadian Prairies; and larger parts of South America, parts of southern and northern Africa, and parts of northwestern Australia.…”
Get full text

Changes of Narrative: Osvald Sirén’s Photographic Modeling of Modern Research on Chinese Garden by Jiuwen GU, Yuanfeng SHI, Shan JIA

“…The combination of this influence and western spatial research has formed a very common paradigm for garden research. …”
Get full text

Clinical Guidelines of the Russian Society of Surgeons, the Russian Gastroenterological Association, the Association of Surgeons-Hepatologists and the Endoscopic Society “REndO” o... by V. T. Ivashkin, A. G. Kriger, A. V. Okhlobystin, M. A. Anischenko, S. S. Kardasheva, S. A. Alekseenko, S. F. Bagnenko, M. I. Bykov, S. A. Budzinskiy, I.  M. Buriev, V. A. Vishnevskiy, E. I. Galperin, V. P. Glabay, V. R. Goltsov, T. G. Dyuzheva, G. G. Karmazanovskiy, M. P. Korolev, D. M. Krasilnikov, Yu. A. Kucheryavy, I. V. Maev, N. A. Maystrenko, M. F. Osipenko, M. I. Prudkov, V. I. Simanenkov, E. G. Solonitsin, A. V. Fedorov, E. D. Fedorov, I. B. Khlynov, M. V. Chikunova, A. V. Shabunin, S. G. Shapovalyants, A. A. Sheptulin, O. S. Shifrin

Get full text

Epidemiological Distribution of Major Ectoparasites Species of Small Ruminant in the Case of Chemical Control Campaign in Welkait District, Tigray Region, Ethiopia by Berhe Leul, Afera Berihun, Kebede Etsay

“…A cross-sectional study was carried out from November 2016 to May 2017 to identify the major ectoparasites species and potential risk factors in Welkait district western part of Tigray region. A total of 102 sheep and 324 goats were physically examined and samples were taken for laboratory analysis. …”
Get full text

Des vestiges d’un possible aqueduc à Lyon, à l’angle des rues Appian et des Fossés-de-Trion by Tony Silvino

“…In ancient times, the site was located in the south-western suburbium of the colony of Lugdunum, a space occupied by a series of different activities, with housing, agricultural areas, areas with craft or commercial activities and even a necropolis. …”
Get full text

Innovative models of healthcare delivery: an umbrella review of reviews by Frances Rapport, Jeffrey Braithwaite, Yvonne Zurynski, Peter D Hibbert, Kate Churruca, Louise A Ellis, Chiara Pomare, Robyn Clay-Williams, Stephanie Best, Janet C Long, Gaston Arnolda, Bróna Nic Giolla Easpaig, Zeyad Mahmoud, Mitchell N Sarkies, Hoa Mi Nguyen, Karen Hutchinson, Gilbert Thomas Knaggs, Katherine Maka, Elizabeth E Austin, Diana Fajardo Pulido, Sarah Hatem, Natalie Roberts, Emilie Francis Auton, Genevieve Dammery, Isabelle Meulenbroeks, Ann Carrigan, Mai-Tran Nguyen

Get full text

High SUVs Have More Robust Repeatability in Patients with Metastatic Prostate Cancer: Results from a Prospective Test-Retest Cohort Imaged with 18F-DCFPyL by Rudolf A. Werner, Bilêl Habacha, Susanne Lütje, Lena Bundschuh, Takahiro Higuchi, Philipp Hartrampf, Sebastian E. Serfling, Thorsten Derlin, Constantin Lapa, Andreas K. Buck, Markus Essler, Kenneth J. Pienta, Mario A. Eisenberger, Mark C. Markowski, Laura Shinehouse, Rehab AbdAllah, Ali Salavati, Martin A. Lodge, Martin G. Pomper, Michael A. Gorin, Ralph A. Bundschuh, Steven P. Rowe

Get full text

A meta-analysis of randomized controlled trials: evaluating the efficacy of isokinetic muscle strengthening training in improving knee osteoarthritis outcomes by Wanqin Guo, Jingyang Gao, Dawazhuoma, Xiuling Mi, Ciwang, Bianba

“…The studies included were randomized controlled trials (RCTs) with participants from the plains who met the diagnostic criteria for KOA as outlined in the 2019 edition, with no restrictions on gender, age, or disease course, and no patients with advanced disease; studies where in the control group was either a non-intervention group or a group receiving treatment, other than IMST, and the experimental group received IMST alone or in addition to the treatment administered to the control group; and studies with at least two of the following outcome indicators: (i) knee flexors (Flex)/extensors (Ext) peak torque (PT), (ii) knee Flex/Ext total work (TW), (iii) knee Flex/Ext max rep total work (MRTW), (iv) knee Flex/Ext average power (AP), (v) visual analogue scale (VAS) for pain, (vi) Lequesne index (LI), (vii) Western Ontario and McMaster University Osteoarthritis Index (WOMAC), (viii) Lysholm Knee Scoring Scale (LKSS), (ix) range of motion (ROM) of the knee joint, and (x) 6-min walk test. …”
Get full text