Autism Spectrum Social Stories In Schools Trial (ASSSIST): study protocol for a feasibility randomised controlled trial analysing clinical and cost-effectiveness of Social Stories... by Dean McMillan, Victoria Allgar, Barry Wright, David Marshall, Shehzad Ali, Joy Adamson, Chris Williams, Elizabeth Littlewood, Dominic Trépel, Lisa Dyson, Hannah Ainsworth, Liz Cook, Lisa Hackney, Danielle Collingridge Moore, Rebecca Hargate, Anne McLaren, Jo Whitehead

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Evaluation for an Open Society: Then and Now by Robert Picciotto

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Individual, household, and community-level factors associated with high-risk fertility behaviour among Nigerian women: secondary analysis of the 2018 demographic and health survey... by Michael Ekholuenetale, Chimezie Igwegbe Nzoputam, Amadou Barrow, Amit Arora

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Relationship between the ideal and reality in civil service: retrospective approach towards ethical problems in the interwar Lithuanian Republic by Jolanta Palidauskaitė

“…Some of them had studied at western universities and were familiar with the newest managerial theories or were writing themselves on various questions including state administration or governance. …”
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Spacer-type tibial osteotomy versus open wedge high tibial osteotomy and unicompartmental knee arthroplasty for Kellgren-Lawrence grade 3–4 medial unicompartmental knee osteoarthri... by Yi Zhang, Xiangzhi Yin, Jinli Chen, Yingze Zhang, Tengbo Yu

“…The clinical outcomes recorded preoperatively and at 6, 12 and 24 months postoperatively were the range of motion (ROM), visual analogue scale (VAS), American Knee Society Score (KSS), Western Ontario and McMaster Universities Global (WOMAC) score, operation time, length of incision, relevant complications and failures. …”
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Esketamine at a Clinical Dose Attenuates Cerebral Ischemia/Reperfusion Injury by Inhibiting AKT Signaling Pathway to Facilitate Microglia M2 Polarization and Autophagy by Gao Y, Li L, Zhao F, Cheng Y, Jin M, Xue FS

“…The expression of biomarkers related to microglial M1 and M2 phenotypes in the ischemic brain tissues was determined by immunofluorescence staining and RT-qPCR, and the expression of proteins associated with autophagy and the AKT signaling pathway in the ischemic brain tissues was assayed by Western blotting.Results: Esketamine alone and esketamine combined with rapamycin alleviated neurological impairment, improved sensorimotor function, decreased cerebral infarct volume, and mitigated tissue injury in the MCAO rats. …”
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Apuntes sobre la medicina interna y los internistas en Cienfuegos by Alfredo Darío Espinosa Brito, Reinaldo José Pino Blanco

“…<p class="western" style="margin-left: 1.5cm; margin-right: 0.09cm; line-height: 150%;" align="justify"><span style="font-size: medium;"><span style="font-family: Tahoma,sans-serif;"><span style="font-size: small;">El propósito de este trabajo es, ante la ausencia de evidencias previas sistematizadas y, mediante un proceso de reconstrucción y reflexión analítica, dar a conocer el desarrollo de la medicina interna y los internistas en Cienfuegos, a partir </span></span><span style="font-family: Tahoma,sans-serif;"><span style="font-size: small;">de la revisión de documentos, registros y referencias disponibles, complementada con el testimonio de las propias vivencias de los autores, participantes activos permanentes en el territorio durante las últimas cinco décadas, así como de los aportes de los colaboradores, para no solo exponer los resultados y explicar cómo se obtuvieron, sino extraer también de ellos, lecciones que permitan continuar mejorándolos en el futuro. …”
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The crisis of the concept of society: historiosophical and sociological search by Irena Eglė Laumenskaitė

“…The present crisis of social transformation in Eastern European countries shows the pseudo-morphosis of Western social-organizational structures due to a hasty transplanting of them into the post-Communist social reality. …”
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Anti-Inflammatory and Anti-Migratory Effects of Morin on Non-Small-Cell Lung Cancer Metastasis via Inhibition of NLRP3/MAPK Signaling Pathway by Punnida Arjsri, Kamonwan Srisawad, Sonthaya Umsumarng, Pilaiporn Thippraphan, Songyot Anuchapreeda, Pornngarm Dejkriengkraikul

“…RT-qPCR measurement quantified the expression of inflammatory genes, and zymography and Western blotting were used to examine changes in invasive protein levels, epithelial-to-mesenchymal transition (EMT) markers, and underlying molecular mechanisms. …”
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NAD⁺激活SIRT3/IDH2信号通路改善高血压血管内皮功能障碍 by 丘雨旻, 陈曦, 张建宁, 刘张弛, 朱秋霞, 张美信, 陶军, 吴杏

“…采用迁移实验和划痕实验评估体外内皮细胞功能；采用免疫荧光染色法检测mtROS水平；采用RT-PCR检测mtDNA、SIRT3、异柠檬酸脱氢酶2（IDH2）的mRNA表达；采用酶联免疫吸附法检测8-羟基-2'-脱氧鸟苷的水平；采用Western blot法检测p-eNOS、eNOS、SIRT3、IDH2蛋白表达水平。结果补充NMN降低了高血压小鼠血压（<italic>P</italic>&lt;0.001），改善内皮功能和动脉僵硬度（<italic>P</italic>&lt;0.001）；体外实验中，NMN可改善Ang Ⅱ刺激所致的内皮细胞舒张功能下降（<italic>P</italic>&lt;0.05）和减轻线粒体氧化应激水平（<italic>P</italic>&lt;0.001）。…”
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Effects of live yeast on milk yield, feed efficiency, methane emissions and fertility of high-yielding dairy cows by P.C. Garnsworthy, N. Saunders, J.R. Goodman, I.H. Algherair, J.D. Ambrose

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IL-33 Deficiency Attenuates Lung Inflammation by Inducing Th17 Response and Impacting the Th17/Treg Balance in LPS-Induced ARDS Mice via Dendritic Cells by Li Cheng, Yang Jiao, Wei Jiang, Xin Zhang, Liping Zhang, Gongwei Jia

“…The levels of IL-33, orphan nuclear receptor gamma t (RORγt), and forkhead transcription factor protein 3 (FOXP3) protein in lung tissue were evaluated by Western blotting. The mRNA expression levels of IL-33 and RORγt were measured by quantitative real-time polymerase chain reaction (qRT-PCR). …”
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Position Paper by Canadian Dental Sleep Medicine Professionals Regarding the Role of Different Health Care Professionals in Managing Obstructive Sleep Apnea and Snoring with Oral A... by Luc Gauthier, Fernanda Almeida, Patrick Arcache, Catherine Ashton-McGregor, David Côté, Helen Driver, Kathleen Ferguson, Gilles Lavigne, Philippe Martin, Jean-François Masse, Florence Morisson, Jeffrey Pancer, Charles Samuels, Maurice Schachter, Frédéric Sériès, Glendon Sullivan

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Efficacy of Esophageal Protector in Treating Gastroesophageal Reflux Disease with Extraesophageal Symptoms: a Multicenter, Open-Label, Observational Study by Yu. A. Kucheryavy, D. N. Andreyev, E. Yu. Eryomina, A. A. Gilmanov, O. V. Nazarova, Ye. A. Sidneva, Yu. G. Topalova

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Regional Differences of Digital Rural Construction in China and Driving Factors by Zeng Yongming, Zhong Zikang

“…Specifically, it is manifested as "high concentration" in parts of the eastern and central regions, and "low concentration" in the western and northeastern regions. In addition, the four sub-dimensional indexes—rural digital infrastructure, rural economic digitalization, rural governance digitalization, and rural life digitalization—show evident spatial differentiation characteristics, with the "Hu Huanyong Line" as the boundary. 3) Regarding mechanism, the spatial panel model was used to verify that government functions, economic foundations, digital foundations, and human capital were important driving factors for the construction of county-level digital rural areas. …”
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Tanshinone I Ameliorates Psoriasis-Like Dermatitis by Suppressing Inflammation and Regulating Keratinocyte Differentiation by Wang Q, Luo X, Su Y, Jin Y, Kuang Q, Li S, Shen W, Zhu Y

“…RNA sequencing (RNA-seq) was performed to investigate Tan-I’s mechanisms in vivo and in vitro, while keratin expression was analyzed by immunofluorescence and Western blot.Results: Tan-I treatment significantly alleviated psoriasis-like lesions in the IMQ mouse model, improving skin pathology and reducing Ki67-positive cells. …”
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Competing sexual-asexual generic names in Agaricomycotina (Basidiomycota) with recommendations for use by Joost A. Stalpers, Scott A. Redhead, Tom W. May, Amy Y. Rossman, Jo Anne Crouch, Marc A. Cubeta, Yu-Cheng Dai, Roland Kirschner, Gitta Jutta Langer, Karl-Henrik Larsson, Jonathan Mack, Lorelei L. Norvell, Franz Oberwinkler, Viktor Papp, Peter Roberts, Mario Rajchenberg, Keith A. Seifert, R. Greg Thorn

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Optimization of laccase production by Pleurotus ostreatus (Jacq.) P. Kumm. using agro-industrial residues: a comparative study on peels of tucumã (Astrocaryum aculeatum G. Mey.) an... by Kevyn Melo Lotas, Raissa Sayumy Kataki Fonseca, Joice Camila Martins da Costa, Ana Claudia Alves Cortez, Francisca das Chagas do Amaral Souza, Márcio Rodrigues Barreto, Lívia Melo Carneiro, João Paulo Alves Silva, Eveleise Samira Martins Canto, Flávia da Silva Fernandes, João Vicente Braga de Souza, Érica Simplício de Souza

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The Transcultural Diabetes Nutrition Algorithm: A Canadian Perspective by Réjeanne Gougeon, John L. Sievenpiper, David Jenkins, Jean-François Yale, Rhonda Bell, Jean-Pierre Després, Thomas P. P. Ransom, Kathryn Camelon, John Dupre, Cyril Kendall, Refaat A. Hegazi, Albert Marchetti, Osama Hamdy, Jeffrey I. Mechanick

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Global, regional, and national disease burden attributable to high systolic blood pressure in youth and young adults: 2021 Global Burden of Disease Study analysis by Chuan He, Saien Lu, Haijie Yu, Yingxian Sun, Xueyao Zhang

“…Regionally, significant improvements in HSBP-related burden were observed in most high-sociodemographic index (SDI) regions, including high-income Asia Pacific (deaths: percentage change, − 72.65%; DALYs: percentage change, − 69.30%) and Western Europe (deaths: percentage change, − 72.89%; DALYs: percentage change, − 67.48%). …”
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