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4201
Disease burden of influenza in Spain: A five-season study (2015–2020)
Published 2025-12-01“…In this period, approximately 7.8% of those hospitalized required ICU admission, and 5.7% died in the hospital due to influenza, with wide differences in these parameters depending on the season due to the virological characteristics of the major circulating viruses. More than 60% of those hospitalized were over 65 years of age, and approximately 82% of those who died were elderly, demonstrating that the greatest burden of hospitalization and mortality is centered on this age group. …”
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4202
All Roads Lead to Rome: Pathways to Engineering Disease Resistance in Plants
Published 2025-02-01“…Additionally, it provides a summary of the potential genes that can be employed in resistance breeding for key crops to combat a wide range of potential pathogens and pests, including fungi, oomycetes, bacteria, viruses, nematodes, and insects. Furthermore, this review addresses the limitations associated with these strategies and their possible solutions. …”
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4203
Assessing spacer acquisition rates in E. coli type I-E CRISPR arrays
Published 2025-01-01“…CRISPR/Cas is an adaptive defense mechanism protecting prokaryotes from viruses and other potentially harmful genetic elements. …”
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4204
Traffic Control of Bacteria-Derived Molecules: A New System of Host-Bacterial Crosstalk
Published 2013-01-01“…Virulent microorganisms, such as pathogenic bacteria and viruses, are recognized by pattern recognition receptors (PRRs), including toll-like receptors (TLRs) and nucleotide-binding oligomerization-domain proteins (NODs), and induce inflammatory responses in mammalian hosts. …”
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4205
Convalescent plasma therapy in severe coronavirus disease-2019: A narrative review
Published 2020-01-01“…Even in the antibiotic era, the use of passive immunization strategy continued to expand with promising results against measles, Ebola, Argentine hemorrhagic fever, and Zika viruses. It was also effective in reducing the mortality and viral load in severe acute respiratory syndrome, H5N1, H1N1, and Middle East Respiratory Syndrome. …”
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4206
Evaluation and Prediction of the HIV-1 Central Polypurine Tract Influence on Foamy Viral Vectors to Transduce Dividing and Growth-Arrested Cells
Published 2014-01-01“…It is hypothesized that this phenomenon might be explained as the inability of foamy viruses to form a pre-integration complex (PIC) with nuclear import activity in growth-arrested cells, which is the characteristic for lentiviruses (HIV-1). …”
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4207
Severe Inflammation Caused by Coinfection of PCV2 and Glaesserella parasuis Is Associated with Pyroptosis via Noncanonical Inflammasome Pathway
Published 2022-01-01“…The revealing of mechanisms associated with coinfection with PCV2 and G. parasuis will provide a scientific basis for investigating the synergistic infection mechanisms between viruses and bacteria.…”
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4208
Portable humidifier for refrigeration systems isolation room in a simple residential house
Published 2025-01-01“…However, being in a dense and dense residential environment can potentially transmit diseases such as infections, bacteria, viruses, airborne microorganisms (airborne microorganisms), fungi, and other sources of infectious diseases. …”
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4209
Effect of a System Air Conditioner on Local Air Quality in a Four-bed Ward
Published 2020-12-01“…Abstract In a ward where many patients are hospitalized, effective ventilation is important because airborne viruses may cause secondary infection. This study investigates the changes in the air quality in a four-bed ward according to the use of a ventilation system (VS), an air cleaner (AC), a system air conditioner (SAC), and personal curtains. …”
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4210
Effect of Ionizers on Indoor Air Quality and Performance of Air Cleaning Systems
Published 2023-12-01“…Abstract Corona ionizers are used to enhance the effectiveness of indoor air cleaners, remove odors, and to promote inactivation of viruses attached to airborne particles. However, there is limited experimental evidence of the effectiveness of ions in indoor air quality, and many commercial products have ambiguous or misleading performance statements. …”
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4211
Efficacy of neem and basil leaf extracts in controlling whitefly (Bemisia Tabaci) infestations and enhancing yield in curly red chili peppers (Capsicum annuum L.)
Published 2024-07-01“… Whiteflies (Bemisia tabaci) are a major pest of curly red chili peppers, acting as vectors for gemini viruses that significantly reduce crop productivity. …”
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4212
Microbiome interplays in the gut-liver axis: implications for liver cancer pathogenesis and therapeutic insights
Published 2025-01-01“…With the advancement of modern medical research and care system, the main etiology of PLC more and more switches from hepatitis viruses such as HAV, HBV, HCV, HEV to other causes like metabolism-associated steatohepatitis (MASH) and metabolic-associated fatty liver disease (MAFLD). …”
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4213
Exploring the link between gut health, diet, and food allergy
Published 2024-09-01“…The gut microbiota refers to the complex ecosystem of microorganisms, including bacteria, archaea, viruses and fungi, that inhabit the human gastrointestinal tract and play a central role in human health, contributing to a range of physiological functions. …”
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4214
Cryo-EM structure of Sudan ebolavirus glycoprotein complexed with its human endosomal receptor NPC1
Published 2025-02-01“…This study provides critical insights into receptor recognition across all viruses in the ebolavirus genus, including their interactions with receptors in bats, their suspected reservoir hosts. …”
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4215
Potential of germanium-based compounds in coronavirus infection
Published 2022-06-01“…Germanium-based compounds have shown the ability to influence the replication of various DNA/RNA viruses, stimulate the body’s natural resistance, prevent the development of metabolic intoxication of various origin, increase the efficacy of vaccines, and prevent the development of excessive accumulation of reactive oxygen species, which plays a decisive role in the development of inflammatory response caused by a viral infection. …”
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4216
Intranasally administrated fusion-inhibitory lipopeptides block SARS-CoV-2 infection in mice and enable long-term protective immunity
Published 2025-01-01“…This strategy provides an additional antiviral approach in the global effort against COVID-19 and may contribute to development of rapid responses against emerging pathogenic viruses.…”
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4217
Cathelicidins: Opportunities and Challenges in Skin Therapeutics and Clinical Translation
Published 2024-12-01“…Produced by immune and epithelial cells, they serve as natural defenses against a wide range of pathogens, including bacteria, viruses, and fungi. In humans, the cathelicidin LL-37 is essential for wound healing, maintaining skin barrier integrity, and combating infections. …”
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4218
Clinical and epidemiological characteristics of confirmed dengue patients. Cumanayagua, Cuba. 2019
Published 2021-06-01“…<br /><strong>Conclusions:</strong> the dengue epidemic in the Cumanayagua municipality in 2019 was clinically-epidemiologically characterized in a similar way to those that occurred in other territories, where the dengue 3 and 4 viruses circulation prevailed.</p>…”
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4219
Specific detection of pigeon parvovirus with TaqMan real-time PCR technology
Published 2025-01-01“…The viruses of the Parvoviridae family can infect both vertebrate and invertebrate animals. …”
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4220
Targeting eEF1A reprograms translation and uncovers broad-spectrum antivirals against cap or m6A protein synthesis routes
Published 2025-02-01“…By deciphering the molecular fingerprint of cells treated with therapies targeting translation we identify a rational approach to select broad-spectrum antivirals with potential to counteract future pandemic viruses.…”
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