Is C-reactive protein sufficient to guide antimicrobial therapy for lower respiratory tract infections among children? Results from a stepped-wedge cluster randomized trial in Uganda. by Chris A Rees, Prashant Mahajan, Quique Bassat

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Prevalence of Helicobacter pylori among Patients with Gastrointestinal Tract (GIT) Symptoms: A Retrospective Study at Selected Africa Air Rescue (AAR) Clinics in Kampala, Uganda, from 2015 to 2019 by Edity Namyalo, Luke Nyakarahuka, Matthias Afayoa, Joel Baziira, Andrew Tamale, G. Collins Atuhaire, Joseph M. Kungu

“…Helicobacter pylori (HP) infection is extremely common worldwide, with almost half of the world’s population infected. In Uganda, no study has been done on the trends of the prevalence of H. pylori infection in the affluent population. …”
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Five lessons from a mid-level health manager intervention to increase uptake of tuberculosis prevention therapy in Uganda: ‘it is a completely different thing to implement what you know.’ by Jason Johnson-Peretz, Canice Christian, Cecilia Akatukwasa, Fred Atwine, Elijah Kakande, Moses R. Kamya, Diane V. Havlir, Carol S. Camlin, Gabriel Chamie

“…Objectives The SEARCH-IPT trial led a series of mini-collaborative meetings, which provided business leadership and management training for an intervention group of mid-level healthcare system managers in rural Eastern, East-Central, and Southwestern Uganda to see whether this would increase uptake of isoniazid-prevention therapy (IPT) for people living with HIV (PLHIV) in intervention districts. …”
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Assessing COVID-19 Pandemic-Era Vaccine Uptake and Adherence to Prevention Measures: A Comparative Analysis Among Men and Women Using Lot Quality Assurance Sampling in Central Uganda by Anguyo RO, Mukama SC, Tasaga C, Bindeeba DS, Senyimba C, Ezajobo S, Nakawesi JS, Mugisa A, Nakubulwa SK, Namitala II E, Aniku G, Katongole SP

“…Robert Onzima DDM Anguyo,1 Semei Christopher Mukama,2 Charles Tasaga,2 Dedrix Stephenson Bindeeba,2 Catherine Senyimba,2 Simons Ezajobo,2 Jane Senyondo Nakawesi,2 Andrew Mugisa,2 Susan Kiwanuka Nakubulwa,2 Eve Namitala II,3 Gilbert Aniku,4 Simon Peter Katongole5 1Department of International Public Health, Liverpool School of Tropical Medicine (LSTM), Kampala, Uganda; 2Mildmay Uganda, Naziba Hill, Lweza, Kampala, Uganda; 3RA International, Medical Department, Mogadishu Somalia, Dubai, United Arab Emirates; 4Department of Paediatrics and Child Health, Arua Regional Referral Hospital, Arua, Uganda; 5School of Public Health, Gudie University Project, Kampala, UgandaCorrespondence: Simon Peter Katongole, Email spkatongole@gmail.comAim: This study examined citizens’ knowledge and compliance with COVID-19 standard operating procedures (SOPs), vaccine acceptance and hesitancy, and factors that could influence these behaviors.Methods: The study that utilised the Lot Quality Assurance Sampling (LQAS) approach was conducted in eight districts of Central Uganda; Kiboga, Kyankwanzi, Mubende, Kasanda, Mityana, Luwero, Nakaseke, and Nakasongola districts. …”
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Susceptibility profile and associated factors of urinary tract infections among women with established preterm labor delivering at a tertiary teaching hospital in Eastern Uganda: a cross-sectional study by Abdirizak Ahmed Ifrah, Marie Pascaline Sabine Ishimwe, Carlos Antonio Batista Cedeño, Eilu Emmanuel, Theoneste Hakizimana

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Mchan Go Wa Utenzi Wa Mw Anakupona Ka Tika Ukuzaji Na Uendelezaji Wa Lugha Ya Kiswahili Miongoni Mwa Vijana Wa Leo Nchini Uganda. by Kobusingye, Eudia

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Mtazamo wa Umma Katika Ulazimishaji wa Ufundishaji wa Lug Hay a Kiswahili Nchini Uganda Tukilenga Wila Yaya Kasese ka Tika Tarafa ya Bwera. by Biira, Felistus

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Barriers and facilitators of integrated hepatitis B, C, and HIV screening among pregnant mothers and newborns attending maternal and newborn clinics in Koboko District, Uganda: a qualitative inquiry of providers’ perspective by John Bosco Alege, John Paul Oyore, Rose Clarke Nanyonga, Philippa Musoke, Alloys S. S. Orago

“…Abstract Background HIV and HBV remain significant public health challenges characterized by high prevalence, morbidity, and mortality, especially among women of reproductive age in Uganda. Patients with HBV do not receive routine counselling and education, and there are limited resources for laboratory investigation coupled with a high loss to follow-up. …”
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Disproportionate Distribution of HBV Genotypes A and D and the Recombinant Genotype D/E in the High and Low HBV Endemic Regions of Uganda: A Wake-Up Call for Regional Specific HBV Management by Hussein Mukasa Kafeero, Dorothy Ndagire, Ponsiano Ocama, Charles Drago Kato, Eddie Wampande, Henry Kajumbula, David Kateete, Abdul Walusansa, Ali Kudamba, Kigozi Edgar, Fred Ashaba Katabazi, Maria Magdalene Namaganda, Jamilu E. Ssenku, Hakim Sendagire

“…Hepatitis B virus (HBV) is the leading cause of liver-related diseases. In Uganda, there is a regional disparity in the HBV burden. …”
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Exploring the experiences of healthcare professionals in South Africa and Uganda around communicating with children about life-threatening conditions: a workshop-based qualitative study to inform the adaptation of communication frameworks for use in these settings by Sue Ziebland, Julia Ambler, Julia Downing, Alan Stein, Elizabeth Namukwaya, Elizabeth Nabirye, Louise Walker, Elizabeth Rapa, Jeffrey R Hanna, Louise J Dalton, Teresa Pollard, Stephanie Santos-Paulo, Yasmin Gogay, David Kavuma, Ruth Mary Kemigisha, Juliet Namyeso, Tracey Brand, Beverley G Neethling

“…Objectives This study aimed to explore how published communication frameworks could be amended to ensure applicability and cultural appropriateness for professionals to support family-centred conversations by investigating’ healthcare professionals’ (1) experiences of providing support to families when a caregiver or a dependent child (<18 years old) has a life-threatening condition, (2) perceived challenges for caregivers and healthcare professionals in communicating with children about illness, (3) perceptions of how clinicians could be equipped to facilitate conversations between caregivers and children about an adult or the child’s own life-threatening condition and (4) suggestions for amendments to previously published guidelines to ensure cultural relevance in South Africa and Uganda.Design A qualitative study involving two 2-day workshops with embedded focus group discussions, break out rooms and consensus discussions.Setting Health and social care and third sector organisations in South Africa and Uganda.Participants Thirty-two professionals providing care to families affected by life-threatening conditions in South Africa or Uganda who were aged 18 years or older and able to converse in English.Results Participants identified obstacles to having conversations with caregivers about children and to telling children about serious illness during consultations. …”
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Uchunguzi wa Sababu za Kuwapo Kwa Wanafunzi Wachache Wanaolichagua Somo la Kiswahili Katika Kiwango Cha “A” Nchini Uganda: Mfano wa Shule za Upili Wilayani Rukungiri. by Mpobwengye, Horeb

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Community Drivers Affecting Adherence to WHO Guidelines Against COVID-19 Amongst Rural Ugandan Market Vendors. by Usman, Ibe Michael, Ssempijja, Fred, Ssebuufu, Robinson, Lemuel, Ann Monima, Archibong, Victor Bassey, Ayikobua, Emmanuel Tiyo, Aruwa, Joshua Ojodale, Kembabazi, Stellamaris, Kegoye, Eric Simidi, Ayuba, John Tabakwot, Okeniran, Olatayo Segun, Echoru, Isaac, Adeoye, Azeez, Mujinya, Regan, Nankya, Viola, Keneth Iceland, Kasozi

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‘I no longer worry about money for transport to the health centre’ - economic empowerment of caregivers of children living with HIV through Village Savings and Loan Associations: experiences and lessons from the 'Towards an AIDS Free Generation Program in Uganda (TAFU)’ by Joseph Rujumba, Carmen Roebersen, Susan Namara, Richard Ochen, Sharon Eva Ahumuza, Allen Tushabe, Mathias Akugizibwe, David Bitira, Innocent Mwesigye, Stella Kentusi, Henry Zakumumpa, Japheth Kwiringira, Merian Natukwatsa Musinguzi

“…Aidsfonds and partners in Uganda implemented an eight-year ‘Towards an AIDS Free Generation in Uganda’ (TAFU) programme in central, western and eastern, Uganda with Village Savings and Loan Associations (VSLAs) as a key component. …”
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Emergency medicine physician supervision and mortality among patients receiving care from non-physician clinicians in a task-sharing model of emergency care in rural Uganda: a retrospective analysis of a single-centre training programme by Rebecca Leff, Brian Rice, Bradley Dreifuss, Heather Hammerstedt, Mark Bisanzo, Stacey Chamberlain, Ashley Pickering, Colleen Laurence, Prisca Mary Kizito, Steven Jonathan Kisingiri, Charles Ndyamwijuka, Serena Nakato, Lema Felix Adriko

“…Objectives To assess the association between emergency medicine physician supervision and 3-day mortality for patients receiving care from non-physician clinicians in a task-sharing model of emergency care in rural Uganda.Design Retrospective cohort analysis with multivariable logistic regression.Setting Single rural Ugandan emergency unit.Participants All patients presenting for care from 2009 to 2019.Interventions Three cohorts of patients receiving care from non-physician clinicians had three different levels of physician supervision: ‘Direct Supervision’ (2009–2010) emergency medicine physicians directly supervised all care; ‘Indirect Supervision’ (2010–2015) emergency medicine physicians were consulted as needed; ‘Independent Care’ (2015–2019) no emergency medicine physician supervision.Primary outcome measure Three-day mortality.Results 38 033 ED visits met inclusion criteria. …”
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