Association between anticholinergic burden and dementia in UK Biobank by Jure Mur, Tom C. Russ, Simon R. Cox, Riccardo E. Marioni, Graciela Muniz‐Terrera

“…Methods Using Cox proportional hazards models, we computed the association between annual anticholinergic burden (AChB) and the risk of dementia in UK Biobank with linked general practitioner prescription records between the years 2000 and 2015 (n = 171,775). …”
Get full text

The role of obesity in mortality from digestive diseases in UK Biobank by Changcong Wang, Xinyue Zhang, Ping Wang, Xinyu Yang, Haitao Yu, Weihang Xu, Liping Chen, Dongmei Mu

Get full text

Hippocampal volumes in UK Biobank are associated with APOE only in older adults by Ariya Chaloemtoem, Vera Thornton, Yoonhoo Chang, Andrey P. Anokhin, Michaël E. Belloy, Janine Bijsterbosch, Brian A. Gordon, Sarah M. Hartz, Laura J. Bierut

Subjects: Get full text

Correction: Mapping of UK Biobank clinical codes: Challenges and possible solutions

Get full text

Insights into the genetic architecture of cerebellar lobules derived from the UK Biobank by Amaia Carrión-Castillo, Cedric Boeckx

Get full text

Correction: Mapping of UK Biobank clinical codes: Challenges and possible solutions. by Oleg Stroganov, Alena Fedarovich, Emily Wong, Yulia Skovpen, Elena Pakhomova, Ivan Grishagin, Dzmitry Fedarovich, Tania Khasanova, David Merberg, Sándor Szalma, Julie Bryant

Get full text

Retinal morphology across the menstrual cycle: insights from the UK Biobank by Ana Paula Ribeiro Reis, Estelle Ioannidou, Siegfried Karl Wagner, Robbert Struyven, Zihan Sun, Paul Foster, Anthony P. Khawaja, Axel Petzold, Sobha Sivaprasad, Nikolas Pontikos, Pearse A. Keane, Konstantinos Balaskas, Elena Greco, Stamatina Iliodromiti, Praveen J. Patel

“…Using self-reported menstrual cycle phases as a surrogate for fluctuating hormonal levels, we investigated associations with retinovascular indices on colour fundus photograph and retinal thickness in optical coherence tomography across regularly menstruating women in the UK Biobank. We found no differences in retinal thickness across the cycle; however, vessel density, arteriolar and venular, and fractal dimension were higher in the luteal phase than follicular. …”
Get full text

Identification of Associations with Dermatologic Diseases through a Focused GWAS of the UK Biobank by Jason C. Klein, Ruchika Mahapatra, Gary C. Hon, Richard C. Wang

Subjects: Get full text

Right hemisphere stroke is linked to reduced social connectedness in the UK Biobank cohort by Katherine O’Connell, Abigail A. Marsh, Anna Seydell-Greenwald

Subjects: Get full text

Investigating the impact of steroid dependence on gastrointestinal surgical outcomes from UK Biobank by Uri Kartoun, Akira Koseki, Akihiro Kosugi, Kingsley Njoku, Tesfaye Yadete, Eileen Koski, Joao Bettencourt-Silva, Natasha Mulligan, Jianying Hu, Julia Liu, Thaddeus Stappenbeck, Vibha Anand

“…We identified subjects in the UK Biobank general practice dataset with at least one major GI surgery and followed them for at least 5 years to evaluate subsequent operations. …”
Get full text

Long-term conditions, multimorbidity and colorectal cancer risk in the UK Biobank cohort by Neave ME Corcoran, Frances S Mair, Barbara Nicholl, Sara Macdonald, Bhautesh Dinesh Jani

“…Methods Longitudinal analysis of the UK Biobank cohort, participants recruited 2006–2010; N = 500,195; excluding previous CRC at baseline. …”
Get full text

Association of ultra-processed food-related metabolites with selected biochemical markers in the UK Biobank by Anthony Kityo, Byeonggeun Choi, Jung-Eun Lee, Chulho Kim, Sang-Ah Lee

Subjects: Get full text

Clustering‐based risk stratification of prediabetes populations: Insights from the Taiwan and UK Biobanks by Djeane Debora Onthoni, Ying‐Erh Chen, Yi‐Hsuan Lai, Guo‐Hung Li, Yong‐Sheng Zhuang, Hong‐Ming Lin, Yu‐Ping Hsiao, Ade Indra Onthoni, Hung‐Yi Chiou, Ren‐Hua Chung

“…ABSTRACT Aims/Introduction This study aimed to identify low‐ and high‐risk diabetes groups within prediabetes populations using data from the Taiwan Biobank (TWB) and UK Biobank (UKB) through a clustering‐based Unsupervised Learning (UL) approach, to inform targeted type 2 diabetes (T2D) interventions. …”
Get full text

The interplay of sex and genotype in disease associations: a comprehensive network analysis in the UK Biobank by Vivek Sriram, Jakob Woerner, Yong-Yeol Ahn, Dokyoon Kim

“…Through comparison of sex-stratified disease-disease networks (DDNs)—where nodes represent diseases and edges represent their relationships—we investigate sex differences in patterns of polygenicity and pleiotropy between diseases. Results Using UK Biobank summary statistics, we built male- and female-specific DDNs for 103 diseases. …”
Get full text

The Health Effects of Dietary Nitrate on Sarcopenia Development: Prospective Evidence from the UK Biobank by Jigen Na, Yuefeng Tan, Yanan Zhang, Xiaona Na, Xiaojin Shi, Celi Yang, Zhihui Li, John S. Ji, Ai Zhao

Subjects: Get full text

Measures of Adiposity and Risk of Testing Positive for SARS-CoV-2 in the UK Biobank Study by Rebecca A. G. Christensen, Shelby L. Sturrock, Jasleen Arneja, Jennifer D. Brooks

“…To assess if body mass index (BMI) and high waist circumference (HWC) are associated with testing positive for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Methods. 9,386 UK Biobank study participants tested for SARS-CoV-2 from March 16th 2020 to June 29th 2020 were analyzed. …”
Get full text

Association of urban environments with Atherosclerotic cardiovascular disease: A prospective cohort study in the UK Biobank by Xuewei Huang, Zhouyi Wang, Fang Lei, Weifang Liu, Lijin Lin, Tao Sun, Yuanyuan Cao, Xingyuan Zhang, Jingjing Cai, Hongliang Li

“…Hence, leveraging the UK Biobank data (n = 206,681), we conducted a prospective analysis of 213 urban environmental variables and their association with atherosclerotic cardiovascular disease (ASCVD). …”
Get full text

Liver Function Biomarkers and Lung Cancer Risk: A Prospective Cohort Study in the UK Biobank by Xiangyu Sun, Zeqin Guo, Yanpei Zhang, Zhuangzhuang Liu, Jingrong Xiong, Mingliang Cai, Jiale Tan, Yan Lin, Zihang Yu, Kunheng Du, Enli Lu, Xiaolin Xia

“…Methods We investigated the associations of seven liver function biomarkers levels (alkaline phosphatase [ALP], alanine transaminase [ALT], total bilirubin [TBIL], albumin [ALB], gamma‐glutamyltransferase [GGT], aspartate transaminase [AST], and total protein [TP]) with lung cancer risk across the UK Biobank (N = 337 499) through restricted cubic splines and Cox proportional hazards models. …”
Get full text

Discriminating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and comorbid conditions using metabolomics in UK Biobank by Katherine Huang, Alex G. C. de Sá, Natalie Thomas, Robert D. Phair, Paul R. Gooley, David B. Ascher, Christopher W. Armstrong

Get full text

Machine learning-based identification of proteomic markers in colorectal cancer using UK Biobank data by Swarnima Kollampallath Radhakrishnan, Dipanwita Nath, Dominic Russ, Dominic Russ, Dominic Russ, Laura Bravo Merodio, Laura Bravo Merodio, Laura Bravo Merodio, Priyani Lad, Folakemi Kola Daisi, Animesh Acharjee, Animesh Acharjee, Animesh Acharjee

Subjects: Get full text