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The DNMT1/miR-34a Axis Is Involved in the Stemness of Human Osteosarcoma Cells and Derived Stem-Like Cells
Published 2019-01-01“…Conversely, DNMT1 overexpression declined miR-34a levels, promoting the stemness of U2OS cells. Transfection with a miR-34a inhibitor enhanced the stemness of U2OS cells, without affecting the DNMT1 activity and expression. …”
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An induced limitation in the reconstruction step for Euler equations of compressible gas dynamics in arbitrary dimension
Published 2024-10-01“…Nevertheless it is in $L^2(\Omega ,\rho )$ as a consequence of the relation on the energies $E=\epsilon + \frac{1}{2} |\mathbf{U}|^2$ in $L^1(\Omega ,\rho )$ (due to global conservation of total energy $\rho E$). …”
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Novel platinum nanoclusters (Pt NCs) induce mitochondrial apoptosis and damaging autophagy for the treatment of osteosarcoma—from the perspective of P53 mutation status in differen...
Published 2024-10-01“…Abstract This study aimed to investigate the anticancer efficacy and underlying mechanism of novel platinum nanoclusters (Pt NCs) in osteosarcoma cell lines exhibiting distinct P53 expression profiles, namely MG-63 (P53−) and U2-OS (P53+). The findings revealed that Pt NCs exerted an inhibitory effect on proliferation, migration, and colony formation while promoting apoptosis in both MG-63 (P53−) and U2-OS (P53+) cells. …”
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Remarks on quasilinear evolutions equations
Published 1991-01-01“…In this paper we study the existence result of classical solutions for the quasilinear equation utt−Δu−M(∫Ω|∇u|2dx)Δutt=f, with initial data u(0)=u0, u(1)=u1 and homogeneous boundary conditions.…”
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Problem With Critical Sobolev Exponent and With Potential on SN
Published 2024-01-01“…We consider the equation −divSNqx∇Snu=u2∗−1,u>0 in D’, u=0 on D′, where D′ is a geodesic ball with radius θ1, centered at the north pole, on SN, N≥4, and q is a positive continuous function. …”
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A Note on the Regularity Criterion of Weak Solutions of Navier-Stokes Equations in Lorentz Space
Published 2012-01-01“…It is proved that the weak solution is regular if the horizontal velocity denoted by ũ=(u1,u2,0) satisfies ũ(x,t)∈Lq(0,T;Lp,∞(R3)) for 2/q + 3/p=1, 3<p<∞. …”
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Nontrivial Solutions for 4-Superlinear Schrödinger–Kirchhoff Equations with Indefinite Potentials
Published 2021-01-01“…This paper is devoted to the 4-superlinear Schrödinger–Kirchhoff equation −a+b∫ℝ3∇u2dxΔu+Vxu=fx,u,in ℝ3, where a>0, b≥0. The potential V here is indefinite so that the Schrödinger operator −Δ+V possesses a finite-dimensional negative space. …”
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On the Existence of Solutions for a Class of Schrödinger–Kirchhoff-Type Equations with Sign-Changing Potential
Published 2022-01-01“…In this paper, we consider the following Kirchhoff problem −a+b∫R3∇u2dxΔu+λVxu=up−2u, in R3u∈H1R3 where a,b>0 are constants, λ is a positive parameter, and 4<p<6. …”
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Solitones singulares y regulares en la ecuación no lineal de Kadomtsev-Petvishvili
Published 2001-01-01“…Se parte de la ecuación de Kadomtsev-Petvishvili para ondas superficiales con dispersión negativa (KP) y mediante transformaciones infinitesimales del método de Lie se llega a la ecuación tipo Boussinesq (TBq) utt uxx + (u2)xx + uxxxx= 0. Se usan las soluciones solitónicas unidimensionales de la ecuación TBq para obtener soluciones solitónicas bidimensionales de la ecuación KP. …”
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H1∩Lp versus C1 Local Minimizers
Published 2014-01-01“…We show that a local minimizer of Φ in the C1 topology must be a local minimizer in the H1∩Lp topology, under suitable assumptions for the functional Φ=(1/2)∫Ω|∇u|2+(1/p)∫Ω|u|p−∫ΩF(x,u) with supercritical exponent p>2∗=2n/(n−2). …”
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First Use of Superpulsed Fibre Thulium Laser-Based Contact Stone Ablation in Common Bile and Main Pancreatic Ducts
Published 2021-06-01“…We describe two clinically successful ablations of large biliary and pancreatic calculi using a FiberLase U2 superpulse fibre thulium laser appliance (IRE-Polus, Russia) during oral transpapillary cholangiopancreaticoscopy in patients with technically unfeasible conventional minimally invasive treatment for choledocho- and pancreatic lithiasis. …”
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Deciphering the regulatory programs of RNA binding proteins in rheumatoid arthritis through single-cell transcriptome analysis
Published 2025-01-01“…Y-Box binding protein 3 (YBX3) and splicing factor 3b subunit 6 (SF3B6) were confirmed to be upregulated in RA-FLS and CIA mice, while eukaryotic translation initiation factor 4A1 (EIF4A1) and U2 small nuclear RNA auxiliary factor 1 (U2AF1) were downregulated in RA-FLS. …”
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Critical singular problems on unbounded domains
Published 2005-01-01“…We present some results of existence for the following problem: −Δu=a(x)g(u)+u|u|2∗−2, x∈ℝN(N≥3), u∈D1,2(ℝN), where the function a is a sign-changing function with a singularity at the origin and g has growth up to the Sobolev critical exponent 2∗=2N/(N−2).…”
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Multiple Nontrivial Solutions for a Nonlocal Problem with Sublinear Nonlinearity
Published 2021-01-01“…In this paper, we study the following nonlocal problem −a−b∫Ω ∇u2dxΔu=λu+fxup−2u,x∈Ω,u=0,x∈∂Ω, where a,b>0 are constants, 1<p<2, λ>0, f∈L∞Ω is a positive function, and Ω is a smooth bounded domain in ℝN with N≥3. …”
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Biharmonic Maps and Laguerre Minimal Surfaces
Published 2013-01-01“…For every Laguerre surface Φ is its associated surface Ψ=1+u2Φ, where u lies in the unit disk. In this paper, the projection of the surface Ψ associated to a Laguerre minimal surface is shown to be biharmonic. …”
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Correlation-guided decoding strategy for low-resource Uyghur scene text recognition
Published 2024-11-01“…Specifically, CGDS improved accuracy by 50.2% on the U1 and 13.6% on the U2 and achieved an overall accuracy improvement of 15.9%.…”
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A Quantum Mermin-Wagner Theorem for a Generalized Hubbard Model
Published 2013-01-01“…Furthermore, we suppose that the potentials U(1), U(2), and V are G-invariant. The result of the paper is that any (appropriately defined) Gibbs states generated by the above Hamiltonian is G-invariant, provided that the thermodynamic variables (the fugacity z and the inverse temperature β) satisfy a certain restriction. …”
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