Showing 1 - 20 results of 328 for search '"Tumor microenvironment"', query time: 0.07s Refine Results
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    Adenosine Concentration Determination for Tumor Microenvironment Simulation by Chun Chen, Chuanpeng Yang, Shuning Hu, Wenjie Nie, Sudan Ye, Minghao Lu, Xingjie Xu, Huajun Hu

    Published 2025-08-01
    “…Objectives We aimed to investigate the concentration of adenosine (ADO) in the tumor microenvironment (TME), focusing on its potential to modulate tumor cells and natural killer (NK) cells, thereby facilitating tumor immune escape. …”
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    A single cell atlas of the human liver tumor microenvironment by Hassan Massalha, Keren Bahar Halpern, Samir Abu‐Gazala, Tamar Jana, Efi E Massasa, Andreas E Moor, Lisa Buchauer, Milena Rozenberg, Eli Pikarsky, Ido Amit, Gideon Zamir, Shalev Itzkovitz

    Published 2020-12-01
    “…Abstract Malignant cell growth is fueled by interactions between tumor cells and the stromal cells composing the tumor microenvironment. The human liver is a major site of tumors and metastases, but molecular identities and intercellular interactions of different cell types have not been resolved in these pathologies. …”
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    A lactate related signature for predicting prognosis and tumor microenvironment in lung adenocarcinoma by Ying Wang, Huiting Li, Chao Chen, Hui Yu, Lichao Xu

    Published 2025-07-01
    “…Abstract Background Lactate plays a critical role in tumor development, metastasis, drug resistance, and regulation of tumor microenvironment. This study aimed to develop a prognostic signature for lung adenocarcinoma (LUAD) based on lactate-related genes (LRGs). …”
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    Decoding the hypoxic tumor microenvironment in colorectal cancer for prognostic modeling and therapeutic target discovery by Xiao-Cui Duan, Yan Zhou, Fan Feng, Hai-Bo Jiang, Mei-Lin Wang, Zhe Han, Hong-Fei Pang, Yu-Hang Liu, Heng-Zhe Jia, Meng- He, Hong-Pan Xu, Yuan-Yuan Wang

    Published 2025-08-01
    “…BackgroundHypoxia is a hallmark of the colorectal cancer (CRC) tumor microenvironment (TME) that drives malignant progression, chemoresistance, and immune evasion. …”
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    Immunosenescence and cancer: molecular hallmarks, tumor microenvironment remodeling, and age-specific immunotherapy challenges by Qianwen Liu, Jingfeng Li, Xiuqiao Sun, Jiayu Lin, Zhengwei Yu, Yue Xiao, Dan Li, Baofa Sun, Haili Bao, Yihao Liu

    Published 2025-08-01
    “…Aging reshapes the tumor microenvironment (TME) through recruitment of immunosuppressive cells, senescence-associated secretory phenotypes (SASP), and metabolic reprogramming, contributing to therapy resistance and poor prognosis in elderly patients. …”
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    Targeting autophagy and plasminogen activator inhibitor-1 increases survival and remodels the tumor microenvironment in glioblastoma by Sophie G. Shifman, Jennifer L. O’Connor, Daniel P. Radin, Aryan Sharma, Laura Infante, Francesca Ferraresso, Christian J. Kastrup, Daniel A. Lawrence, Stella E. Tsirka

    Published 2025-07-01
    “…A critical factor for GBM survival is communication with the tumor microenvironment (TME), which can be programmed by glioma cells to support growth and immunosuppression. …”
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