The Immediate Effects of Foam Rolling and Stretching on Iliotibial Band Stiffness: A Randomized Controlled Trial by Talin M Pepper, Jean-Michel Brismée, Phillip S Sizer Jr, Jeegisha Kapila, Gesine H Seeber, Christopher A Huggins, Troy L Hooper

“… # Study Design Randomized controlled trial. # Methods Data from 11 males (age = 30.5 ± 9.0 years, Body Mass Index (BMI) = 27.8 ± 4.0) and 19 females (age = 23.5 ± 4.9, BMI = 23.2 ± 2.1) were analyzed for this study. …”
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The Effects of Baclofen for the Treatment of Gastroesophageal Reflux Disease: A Meta-Analysis of Randomized Controlled Trials by Shujie Li, Shengying Shi, Feng Chen, Jingming Lin

“…We systematically searched randomized controlled trials published prior to November 2013 from PubMed, Medline, Embase, ScienceDirect, ClinicalTrials.gov, and the Cochrane Central Register of Randomized Controlled Trials. …”
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Evaluation of a Guided Chatbot Intervention for Young People in Jordan: Feasibility Randomized Controlled Trial by Anne Marijn de Graaff, Rand Habashneh, Sarah Fanatseh, Dharani Keyan, Aemal Akhtar, Adnan Abualhaija, Muhannad Faroun, Ibrahim Said Aqel, Latefa Dardas, Chiara Servili, Mark van Ommeren, Richard Bryant, Kenneth Carswell

“…Trial RegistrationISRCTN ISRCTN19217696; https://doi.org/10.1186/ISRCTN19217696…”
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Associations of Serum Urate and Cardiovascular Events in a Clinical Trial of Interleukin-1β Blockade by Nicholas H. Adamstein, MD, Jean G. MacFadyen, BA, Brittany N. Weber, MD, PhD, Peter Libby, MD, Daniel H. Solomon, MD, MPH, Paul M Ridker, MD, MPH

“…Objectives: The purpose of this study was to assess whether SU predicts CV risk in a trial of interleukin (IL)-1β inhibition with canakinumab, and whether IL-1β blockade, kidney function, or gout alter these associations. …”
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Exercise training and chronic kidney disease: characterization and bibliometrics of citation classics of clinical intervention trials by Fan Zhang, Shan Liu, Yan Bai, Liuyan Huang, Yifei Zhong, Yi Li

“…This study analyzes citation classics on clinical intervention trials on exercise training and CKD to describe the research landscape and hotspots through bibliometric analysis.Methods To identify clinical trials of exercise training interventions for CKD with more than 100 citations from the Web of Science Core Collection database. …”
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High intensity transcranial altering current stimulation for cognitive dysfunction in schizophrenia: A pilot trial by Zifan You, Zhangyin He, Luyao Zou, Shanshan Chen, Jinsong Tang

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Effectiveness of Mobilization with Movement on the Management of Knee Osteoarthritis: A Systematic Review of Randomized Controlled Trials by Gidey Gomera Weleslassie, Melaku Hailu Temesgen, Abayneh Alamer, Gebrerufael Solomon Tsegay, Teklehaimanot Tekle Hailemariam, Haimanot Melese

“…Only randomized controlled trials (RCTs) were included, and the methodological quality of the studies was appraised using the PEDro scale. …”
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Toxicity Associated with Pembrolizumab Monotherapy in Patients with Gastrointestinal Cancers: A Systematic Review of Clinical Trials by Nikolas Naleid, Amit Mahipal, Sakti Chakrabarti

“…<b>Methods:</b> A comprehensive search of PubMed/MEDLINE was performed to identify clinical trials investigating pembrolizumab monotherapy in GI cancer patients. …”
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Evaluating Mirror Therapy Protocols in Phantom Limb Pain Clinical Trials: A Scoping Review by Limakatso K, McGowan E, Ortiz-Catalan M

“…Establishing a standardized treatment protocol could enhance the reliability and reproducibility of treatment outcomes in future studies and ensure a meaningful comparison between mirror therapy and other treatments in clinical trials and meta-analyses.Keywords: amputation, phantom limb pain, mirror therapy, rehabilitation…”
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Phage Cocktail Alleviates Bacterial Canker of Kiwifruit by Modulating Bacterial Community Structure in Field Trial by Ran Hu, Xiaohan Xu, Yajun Jia, Cancan Zhu, Lin Wang, Minxin Song, Qian Xu, Mian Xia, Xiaoqing He, Yi Jin

“…In this study, the field trial results showed that phage cocktail could significantly reduce the incidence of bacterial canker in kiwifruit. …”
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Assessing patient risk, benefit and outcomes in drug development: an observational study of regorafenib clinical trials by Matt Vassar, Vinay Prasad, Ryan McIntire, Alyson Haslam, Brody Dennis, Chance Bratten, Griffin K Hughes, Andriana M Peña, Chase Ladd, Brooke Gardner, William Nowlin, Reagan Livingston, Jordan Tuia

“…To regenerate what they’ve spent, drug manufacturers may attempt to repurpose their medications for new indications via clinical trials. To fully understand the risk/benefits in comparison to a drug’s efficacy, a pooled analysis must be completed.Methods We screened PubMed, Embase, Cochrane (CENTRAL) and ClinicalTrials.gov for trials of regorafenib used to treat solid cancers. …”
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When ‘Law’ Rhymes with ‘Flaw’: the Sounds of British Justice in Gilbert and Sullivan’s Trial by Jury (1875) by Joël Richard

“…Gilbert and Sullivan’s second operatic collaboration, Trial by Jury (1875) is often discarded as a ‘minor’ work, compared to their later, better-known operas such as The Pirates of Penzance (1879), The Mikado (1885) or The Gondoliers (1889). …”
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Effectiveness of a training program for the acquisition of motor milestones in infants: a randomized clinical trial by Luis Fernández-Sola, Beatriz Cano-Díez, Yessica Pons-Solaz, Begoña Vera-Egido, Sergio Moreno-González

“…Future studies using larger sample sizes, analysing other domains of global infant development, or investigating the possible influence of other parental factors are recommended. Trial registration ClinicalTrials.gov ID NCT04693494. …”
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Priming and task‐specific training for arm weakness post stroke: A randomized controlled trial by Erin C. King, Jacob M. Schauer, Shyam Prabhakaran, Alexandra Wax, Sebastian Urday, Sangeetha Madhavan, Daniel M. Corcos, Mary Ellen Stoykov

“…Methods In this single‐blind, randomized controlled trial, 76 adults with moderate to severe upper limb hemiparesis ≥6 months post‐stroke were stratified by baseline impairment and randomized to receive either BUMP or CP prior to receiving the same TST protocol. …”
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Feasibility and accuracy of continuous intraabdominal pressure monitoring with a capsular device in human pilot trial by Chien-Hung Liao, David A. Spain, Chih-Chi Chen, Chi-Tung Cheng, Wei-Cheng Lin, Dong-Ru Ho, Heng-Fu Lin, Fausto Catena

“…Method We conducted a prospective clinical trial to evaluate the feasibility of IAP measurement using a digital capsule PressureDOT, an ingestible capsule equipped with wireless transmission capability and a pressure sensor, then compared its reliability with conventional intravesical method. …”
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The Challenges of Conducting a Nurse-Led Intervention in a Randomized Controlled Trial with Vulnerable Participants by Tanya Park, Kim Usher, Kim Foster

“…This paper discusses the challenges encountered by researchers while conducting a randomized controlled trial (RCT) testing the efficacy of a healthy lifestyle educational and exercise intervention for people with serious mental illness. …”
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Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial by Mir Sadat-Ali, Abdallah S. AlOmran, Sulaiman A. AlMousa, Hasan N. AlSayed, Khalid W. AlTabash, Mohammed Q. Azam, Tarek M. Hegazi, Sadananda Acharya

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Two Oral Midazolam Preparations in Pediatric Dental Patients: A Prospective Randomised Clinical Trial by Katayoun Salem, Shaqayegh Kamranzadeh, Maryam Kousha, Shahnaz Shaeghi, Fatemeh AbdollahGorgi

“…Eighty-eight children between 4 to 7 years of age received 0.2–0.5 mg/kg midazolam in this parallel trial. Physiologic parameters were recorded at baseline and every 15 minutes. …”
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Efficacy of Robotic-Assisted Prostatectomy in Localized Prostate Cancer: A Systematic Review of Clinical Trials by Carolina Sandoval Salinas, Andrés L. González Rangel, Juan G. Cataño Cataño, Juan C. Fuentes Pachón, Juan S. Castillo Londoño

“…However, some differences in patient-related outcomes favor the newer methods. Larger trials are required.…”
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The use of paracetamol during pregnancy: A qualitative study and possible strategies for a clinical trial. by Cathrine Vedel, Ditte Staub Jørgensen, David Møbjerg Kristensen, Olav Bjørn Petersen, Gorm Greisen

“…It highlights the urgent need for a clinical trial, and the aim of the presented qualitative pilot study on APAP use during pregnancy is the feasibility of a large-scale randomized controlled trial (RCT). …”
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