The impact of innate immune response on the efficacy of oncolytic viruses by Kirill N. Trachuk, Nikolai B. Pestov, Yulia K. Biryukova, Nadezhda M. Kolyasnikova

“…Recently, there have emerged more studies determining the effect of the antiviral immunostimulating mechanisms on the effectiveness of treatment in cancer patients. Stimulation of innate immune cells by an oncolytic virus can initiate an adaptive antitumor immune response, yet at the same time, the antiviral mechanisms of the immune system can limit the spread of the virus, thereby reducing its effectiveness. …”
Get full text

A comparative study of replicative properties of antitumor recombinant vaccinia viruses on human glioblastoma cell culture U87 and monkey kidney cell culture CV-1 by R. A. Maksyutov, I. V. Kolosova, T. V. Tregubchak, I. A. Razumov, S. N. Shchelkunov

“…In the world of today, virotherapy is one of the rapidly developing areas in the treatment of cancer, and its advantage is selective destruction of cancer cells with minimizing the destructive effect on normal cells of the body. …”
Get full text

Diagnostic and therapeutic recommendations for chronic pancreatitis. Recommendations of the Working Group of the Polish Society of Gastroenterology and the Polish Pancreas Club by Roland Kadaj-Lipka, Michał Lipiński, Krystian Adrych, Marek Durlik, Anita Gąsiorowska, Mirosław Jarosz, Grażyna Jurkowska, Ewa Małecka-Panas, Grzegorz Oracz, Mariusz Rosołowski, Barbara Skrzydło-Radomańska, Renata Talar-Wojnarowska, Grażyna Rydzewska

Get full text

Curing Opioid Toxicity with Intrathecal Targeted Drug Delivery by Thomas P. Pittelkow, Markus A. Bendel, Jacob J. Strand, Susan M. Moeschler

“…Despite well-established guidelines set forth by the World Health Organization (WHO) on the treatment of cancer pain, nearly half of cancer patients report poorly controlled pain. …”
Get full text

Morphine in Combination with Ketamine Improves Cervical Cancer Pain and Suppresses Immune Function via the JAK3/STAT5 Pathway by Yurong Jiang, Tong Li, Yi Qian, Xiaoming Zuo, Jinmei Liu

“…The role of ketamine as an adjuvant for morphine in the treatment of cancer pain and immune functions has been confirmed. …”
Get full text

Advanced surface-enhanced raman scattering nanoprobes for precise detection of Nitroreductase in Hypoxic tumor cells: Improving Cancer diagnosis by Xiaoyue Zhao, Ying Zhang, Chunyan Zhu, Zhihui Yang, Xiaoyuan Chu

“…Nitroreductase (NTR) plays a critical role in the oxygen-deficient environment of anoxic tumor cells, and its identification is crucial for the diagnosis and treatment of cancer. This research introduces an innovative Surface Enhanced Raman Scattering (SERS) probe, created by attaching p-nitrothiophenol (p-NTP) to gold nanoparticles (Au NPs). …”
Get full text

Poly lactic‐co‐glycolic acid‐alginate nanocarrier for efficient drug delivery to liver cancer cells by Mahsa Hoseinzadeh, Mohammad Javad Mokhtari, Farshid Kafilzadeh, Javad Mohammadnejad, Yaghoob Taheri

“…The IC50 value was observed for 100 nM after 24 h of treatment in cancer cells. These data have indicated that fabricated nanocarrier could be promising DDS against liver cancer and replace with conventional approaches in cancer treatment, like chemotherapy.…”
Get full text

Gene Editing in Pluripotent Stem Cells and Their Derived Organoids by Hang Zhou, Yun Wang, Li-Ping Liu, Yu-Mei Li, Yun-Wen Zheng

“…Gene editing in PSCs creates visualized in vitro models, providing opportunities for examining mechanisms of known and unknown mutations and offering new possibilities for the treatment of cancer, genetic diseases, and other serious or refractory disorders. …”
Get full text

Surgical treatment can provide the opportunity for in-vitro fertilization (IVF) in a shorter period of time for patients with early-stage endometrial cancer by Qianhua Xu, Hedong Lu, Xiaolei Wang, Min Li, Weiwei Zou

Get full text

Role of Natural Radiosensitizers and Cancer Cell Radioresistance: An Update by Arif Malik, Misbah Sultana, Aamer Qazi, Mahmood Husain Qazi, Gulshan Parveen, Sulayman Waquar, Abdul Basit Ashraf, Mahmood Rasool

“…To overcome radioresistance in treatment of cancer, strategies like fractionation modification, treatment in combination, inflammation modification, and overcoming hypoxic tumor have been practiced. …”
Get full text

Universal Health Care for Childhood Cancer in India: Challenges and Solutions for Implementation by Anukriti Srivastava, Nita Radhakrishnan, Archit Pandharipande, Zeenat Brar, Amit Pandey

“…Methods: The data of children aged between 0-18 years who underwent treatment for cancer with financial support from PMJAY scheme between Jan 2018 to December 2022 (5 years) was analyzed from hospital records. …”
Get full text

The Role of Inspiratory Muscle Training in Sickle Cell Anemia Related Pulmonary Damage due to Recurrent Acute Chest Syndrome Attacks by Burcu Camcıoğlu, Meral Boşnak-Güçlü, Müşerrefe Nur Karadallı, Şahika Zeynep Akı, Gülsan Türköz-Sucak

“…Functional exercise capacity was evaluated using six-minute walk test, respiratory muscle strength using mouth pressure device, hand grip strength using hand-held dynamometer, pain using Visual Analogue Scale, fatigue using Fatigue Severity Scale, dyspnea using Modified Medical Research Council Scale, and health related quality of life using European Organization for Research and Treatment of Cancer QOL measurement. Results. A significant improvement has been demonstrated in respiratory muscle strength, functional exercise capacity, pain, fatigue, dyspnea, and quality of life. …”
Get full text

Etoricoxib–NLC Mitigates Radiation-Induced Ovarian Damage in Rats: Insights into Pro-Inflammatory Cytokines, Antioxidant Activity, and Hormonal Responses by Sahar Khateeb

“…Radiotherapy is a critical treatment for cancer but poses significant risks to ovarian tissue, particularly in young females, leading to premature ovarian failure (POF). …”
Get full text

Psychological Well-being of Cancer Patients by R.N. Mustafin, E.A. Kalyuzhny

“…An important factor in successful treatment of cancer patients is psychological well-being, including the presence of positive emotions, engagement, meaning in life, autonomy, positive relationships with others, self-acceptance, and absence of psychological disorders. …”
Get full text

Currents status of radiotracers for breast cancer imaging in PET by Chloé Jean, Stéphane Roux, Abdelilah Aziz, Maxence Mocquery-corre, Rana Bazzi, Yacine Merrouche, Stéphane Dedieu, Nicolas Etique, Dimitri Papathanassiou, Jérôme Devy

“…Radiolabeled molecules have become valuable tools in the diagnosis, monitoring, and treatment of cancer, particularly breast cancer. Through the use of radiotracers, clinicians can target specific tumor cells, assess microenvironments, and identify metastases. …”
Get full text

Infertility and risk of ovarian cancer: A systematic review and meta analysis by Indra Sambasivam, H. Gladius Jennifer, Saravanan Chinnaiyan

“…Recent studies have shown that a substantial proportion of couples undergoing infertility treatment develop cancer. However, existing studies yielded inconsistent results. …”
Get full text

Risk Factors Analysis of Cutaneous Adverse Drug Reactions Caused by Targeted Therapy and Immunotherapy Drugs for Oncology and Establishment of a Prediction Model by Zimin Zhang, Mingyang Zhu, Weiwei Jiang

“…Nine risk factors were eventually identified: age, treatment modality, cancer types, history of allergies, age‐corrected Charlson comorbidity index, percentage of eosinophils, absolute number of monocytes, Eastern Cooperative Oncology Group Performance Status, and C‐reactive protein. …”
Get full text

Molecular Mechanisms Contributing Bacterial Infections to the Incidence of Various Types of Cancer by Salah A. Sheweita, Awad S. Alsamghan

“…In addition, it is important to know the possible factors involved in cancer induction for better treatment of cancer patients.…”
Get full text

The interplay of exercise and green tea: a new road in cancer therapy by Bing Liu, Heyu Tian, Mohammad Reza Momeni

“…In particular, the focus of this research will be on examining how oxidative stress contributes to health and investigating the potential antioxidant properties of green tea, and the interconnected relationship between exercise and green tea in the treatment of cancer. Elucidation of these different pathways would help scientists for development of better therapeutic targets and further increase of current anticancer agents efficiency.…”
Get full text

Intervention program through therapeutic physical exercise in patients with lung cancer by Onesio Esteban de León Gutierrez, Israel Triana Pérez, Iván Castillo Ledo

“…The analyzed variables: age, sex, start time of rehabilitation, symptoms and quality of life; the latter using the European organization for research and treatment of cancer quality life questionnaire core 30. …”
Get full text