Showing 921 - 940 results of 3,629 for search '"Toxicity"', query time: 0.06s Refine Results
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    PREDICCIÓN DE TOXICIDAD ACUÁTICA MEDIANTE QSAR TOOLBOX: UN ENFOQUE IN SILICO PARA LA EVALUACIÓN DE RIESGOS QUÍMICOS EN LA FRACTURACIÓN HIDRÁULICA by Adolfo E. Ensuncho, Diana B. Ramírez, Jesús M. López

    Published 2025-01-01
    “…The results show that QSAR toolbox can predict aquatic toxicity, using the log Kow hydrophobicity descriptor and through this it’s observed that, in the three aquatic species, aldrin exhibits a high degree of toxicity compared to the other chemicals. …”
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  10. 930

    Phytochemical and toxicological evaluation of aqueous leaf extract of Premna integrifolia L. in male balb/c mice by Suman, Pratibha Gaurav, Rajesh Saini, Kavindra Nath Tiwari, Gautam Geeta Jiwatram

    Published 2025-02-01
    “…The acute and subacute toxicity studies of the ALEPI provided a comprehensive evaluation of its safety profile. …”
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  11. 931

    Two- and Three-Dimensional Culture Systems: Respiratory In Vitro Tissue Models for Chemical Screening and Risk-Based Decision Making by Joanne Wallace, Mary C. McElroy, Mitchell Klausner, Richard Corley, Seyoum Ayehunie

    Published 2025-01-01
    “…Here we review 2D and 3D lung models in terms of their application for inhalation toxicity assessment. We highlight a key case study for the Organization for Economic Cooperation and Development (OECD), in which a 3D model was used to assess human toxicity and replace the requirement for a 90-day inhalation toxicity study in rats. …”
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    Evaluation of phenylethylamine type entactogens and their metabolites relevant to ecotoxicology – a QSAR study by Takač Milena Jadrijević-Mladar, Magina Joao Daniel Casimiro, Takač Tin

    Published 2019-12-01
    “…The impact of the selected entactogens and their o-quinone metabolites on the environment was explored in QSAR studies by the use of predicted molecular descriptors, ADMET properties and environmental toxicity parameters, i.e., acute toxicity in Tetrahymena pyriformis (TOX_ATTP) expressed as Th_pyr_pIGC50/mmol L−1, acute toxicity in Pimephales promelas, the fathead minnow (TOX_FHM) expressed as Minnow LC50/mg L−1, the acute toxicity in Daphnia magna (TOX_DM) expressed as Daphnia LC50/mg L−1 and bioconcentration factor (BCF).…”
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  14. 934

    Once-Daily Dosing of Aminoglycosides by William A Craig

    Published 1994-01-01
    “…Similar efficacy and toxicity were observed in all the oilier studies. CONCLUSIONS: Once-daily dosing of aminoglycosides has the potential to enhance efficacy, reduce toxicity and lower administration costs for this drug class. …”
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  15. 935

    Application of iron on improving antimony tolerance in Salvia spinosa by Shakiba Rajabpoor, Soghra Kiani, Shokoofeh Hajihashemi

    Published 2025-02-01
    “…Antimony (Sb) is a potential threat to living organisms, but very little is known on strategies manage its toxicity in plants. This study aimed to clarify the role of Fe on alleviation Sb toxicity in a metallicolous population of Salvia spinose and its mechanisms. …”
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  16. 936

    Standardization of Alternative Methods for Nanogenotoxicity Testing in Drosophila melanogaster Using Iron Nanoparticles: A Promising Link to Nanodosimetry by Venkatachalam Deepa Parvathi, Kalyanaraman Rajagopal, Ravindran Sumitha

    Published 2016-01-01
    “…Research studies (in vitro model) have demonstrated the lack of toxicity in nanoiron. The present study design involves in vivo toxicity assessment of nanoiron at specific concentrations of 0.1 mM, 1 mM, 5 mM, and 10 mM in Drosophila. …”
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  17. 937

    Severe Neurotoxicity due to Atropa belladonna Poisoning: A Case Report and Literature Review by Seyed Javad Boskabadi, Sima Ramezaninejad, Zakaria Zakariaei

    Published 2024-01-01
    “…These cases highlight the importance of awareness regarding the potential toxicity of A. belladonna and the necessity of prompt and appropriate management of its toxicity. …”
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    Anticancer Activity of Rhizophora mucronata Leaves Extract on Sprague–Dawley Rats: In Vivo Model by Asbin Mary X, Syed Ali Mohamed Yacoob, Anuradha Venkatraman, Ruban Packiasamy, Meivelu Moovendhan, Murugesan Gnanadesigan, Yogananth Nagarajan

    Published 2023-01-01
    “…In acute toxicity trials, the dose of 1000 mg/kg body weight was determined to be safe and nontoxic even at high dose levels and did not result in any indicators of toxicity or death in the tested groups compared to controls for 14 days. …”
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  20. 940

    The development and evaluation of a tublysine-based antibody-drug conjugate with enhanced tumor therapeutic efficacy by Huihui Guo, Hongsheng Xie, Yuanyuan Huang, Junxiang Jia, Xiangfei Kong, Qingliang Yang, Shun Gai, Wenjun Li, Lu Bai, Lingli Zhang, Xiaoxiao Chen, Zhicang Ye, Hangbo Ye, Linyao Zhao, Yifang Xu, Yong Du, Xiuzhen Zhang, Miaomiao Chen, Xiaomai Zhou, Robert Y. Zhao

    Published 2025-02-01
    “…In repeated-dose toxicity studies, DX126-262 was well tolerated in rats at doses up to 200 mg/kg, with the highest non-severely toxic dose (HNSTD) established at 100 mg/kg. …”
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