Toxic Epidermal Necrolysis (TEN)/Stevens-Johnson Syndrome (SJS) Epidemiology and Mortality Rate at King Fahad Specialist Hospital (KFSH) in Qassim Region of Saudi Arabia: A Retrospective Study by Abdullah Alajaji, Jagannath Chandra Shekaran, Omar Mohammed Aldhabbah, Hajar Abdullah Alhindi, Nouf Salem Almazyad, Ziyad Abdulrahman Aljutayli, Saleh Abaalkhail, Saleh Alfouzan

“…Background. Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are life-threatening conditions caused by drug reactions. …”
Get full text

CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases by Arthur I. Cederbaum, Lili Yang, Xiaodong Wang, Defeng Wu

“…A major mechanism is the role of lipid peroxidation and oxidative stress in alcohol toxicity. Many pathways have been suggested to play a role in how alcohol induces oxidative stress. …”
Get full text

Air Quality Assessment by Moss Biomonitoring and Trace Metals Atmospheric Deposition by Pranvera Lazo, Alda Kika, Flora Qarri, Lirim Bekteshi, Shaniko Allajbeu, Trajce Stafilov

Subjects: Get full text

Seasonal Changes in the Elemental Composition of Five Valuable Fish Species (<i>Sparidae</i>) from Bozcaada, North Aegean Sea: A Health Risk and Nutritional Benefit Assessment by İlknur Yuvka, Ali Rıza Kosker, Mustafa Durmus, Yılmaz Ucar, Yesim Ozogul

Subjects: Get full text

Fluorescence Polarization Immunoassay for Rapid, Sensitive Detection of the Herbicide 2,4-Dichlorophenoxyacetic Acid in Juice and Water Samples by Liliya I. Mukhametova, Marya K. Kolokolova, Ivan A. Shevchenko, Boris S. Tupertsev, Anatoly V. Zherdev, Chuanlai Xu, Sergei A. Eremin

Subjects: Get full text

TO THE ISSUE OF REDUCING ENVIRONMENTAL RISKS OF A TRANSPORT ENTERPRISE BASED ON RATIONAL NATURE MANAGEMENT by L. Makolova

Subjects: Get full text

Adsorption and Recovery Studies of Cadmium and Lead Ions Using Biowaste Adsorbents from Aqueous Solution by Liang Feng, Enju Wang

Subjects: Get full text

Ecological monitoring of landscape technogenic neoplasms by Daria A. Dostovalova, Alexander Z. Glukhov, Nikolay S. Podgorodetsky, Sergey P. Zhukov

Subjects: Get full text

ENVIRONMENTAL ASPECTS OF THE TRANSPORT SYSTEM OF CITIES OF THE RUSSIAN FEDERATION

Subjects: Get full text

A humanized anti-MSLN×4-1BB bispecific antibody exhibits potent antitumour activity through 4-1BB signaling activation and fc function without systemic toxicity by Da-yan Zhang, Zhi-hua Zhang, Wen-ting Liu, Wei-ming Zhou, Peng-fei Zhou, Juan-juan Wei, Xue-jing Dai, Xiao-li Zeng, Yu-qiong Zhou, Han-wang Li, Heng Zhang, Ao-lin Shen, Lian-sheng Cheng, Guo-dong Shen, Yi-fu He

“…Abstract Background Agonistic monoclonal antibodies targeting 4-1BB/CD137 have shown preclinical promise, but their clinical development has been limited by severe liver toxicity or limited efficacy. Therefore, a safe and efficient immunostimulatory molecule is urgently needed for cancer immunotherapy. …”
Get full text

Crustacean Zooplankton Ingestion of Potentially Toxic <i>Microcystis</i>: In Situ Estimation Using <i>mcyE</i> Gene Gut Content Detection in a Large Temperate Eutrophic Lake by Helen Agasild, Margarita Esmeralda Gonzales Ferraz, Madli Saat, Priit Zingel, Kai Piirsoo, Kätlin Blank, Veljo Kisand, Tiina Nõges, Kristel Panksep

Subjects: Get full text

RadBone: bone toxicity following pelvic radiotherapy – a prospective randomised controlled feasibility study evaluating a musculoskeletal health package in women with gynaecological cancers undergoing pelvic radiotherapy by Janelle Yorke, Sarah O’Connell, Sally Taylor, Karen Johnson, Robert G Bristow, Martin Eden, Kate Haslett, John Moore, Rohit Kochhar, Victoria Chatzimavridou Grigoriadou, Lisa H Barraclough, Ivona Baricevic-Jones, Zoe Merchant, Thomas Westwood, Anthony David Whetton, Claire E Higham

Get full text

A Low-Cost Electrochemical Cell Sensor Based on MWCNT-COOH/α-Fe₂O₃ for Toxicity Detection of Drinking Water Disinfection Byproducts by Ying Liu, Zhipeng Zhang, Yuling Wu, Huan Yang, Jiao Qu, Xiaolin Zhu

“…Moreover, the safety of these DBPs has not been sufficiently assessed, underscoring the need for a comprehensive evaluation of their toxic effects and associated health risks. Compared to traditional methods for studying the toxicity of pollutants, emerging electrochemical sensing technologies offer advantages such as simplicity, speed, and sensitivity, presenting an effective means for toxicity research on pollutants. …”
Get full text

Unveiling emerging polycyclic aromatic compounds in the urban atmospheric particulate matter by Jia-Yong Lao, Tingyu Li, Le Jing, Xian Qin, Wenyuan Su, Huiju Lin, Yuefei Ruan, Ting Ruan, Eddy Y. Zeng, Kenneth M.Y. Leung, Paul K.S. Lam

Subjects: Get full text

Effects of orally exposed SiO2 nanoparticles on lipid profiles in gut-liver axis of mice by Kuanhang Li, Zhengzheng Zhou, Yi Cao

Subjects: Get full text

Aluminum tolerance and micronutrient content in the grain of oat cultivars with different levels of breeding improvement from the VIR collection by I. G. Loskutov, V. Butris, I. A. Kosareva, E. V. Blinova, L. Yu. Novikova

Subjects: Get full text

hERGAT: predicting hERG blockers using graph attention mechanism through atom- and molecule-level interaction analyses by Dohyeon Lee, Sunyong Yoo

Subjects: “…Drug toxicity…”
Get full text

In-depth study of the nutritional composition, phytochemicals, antioxidant activity, molecular docking interactions, and toxicological evaluation of Abies marocana Trab. woody biom... by Malak Zirari, Marouane Aouji, Wissal Baghdad, Mohammed Er-rajy, Hamada Imtara, Feras Abujaber, Otmane Elharrati, Omar M. Noman, Mahmoud Tarayrah, Driss Hmouni, Nouredine El Mejdoub

Subjects: Get full text

Fungal and oomycete pathogens and heavy metals: an inglorious couple in the environment by Joanna Gajewska, Jolanta Floryszak-Wieczorek, Ewa Sobieszczuk-Nowicka, Autar Mattoo, Magdalena Arasimowicz-Jelonek

Subjects: Get full text

Heavy metal and metalloid pollution: A systematic review of health implications for pregnant women, children, and geriatrics in the East African region by Godswill J. Udom, Brian Turyahabwe, Ayodeji Aturamu, Omoirri M. Aziakpono, Richard D. Agbana, Omole G. Joseph, Nita-wills G. Udom, Nuru Mugide, Omali P. Odey, Haron Olot, Orish E. Orisakwe

Subjects: Get full text