Experience in the management of patients with HTLV-1 positive adult T-cell leukemia/lymphoma in a Latin American center by Danielle Floyd-Aristizábal, Cristian Alonso Barreiro García, Oriana Arias-Valderrama, Catalina Proaño Millán, Nhora María Silva Perez, Joaquín Donaldo Rosales Martinez, Elizabeth Arrieta López

“…Further research is needed to improve treatment strategies, identify prognostic markers, and develop more effective therapies for ATL patients in Colombia.…”
Get full text

Research Hotspots and Trends in Acupuncture for Cancer:A bibliometric analysis from 2004 to 2024 by Ji Z, Niu H, He A, Li K, Jia J, Zhang M, Liu G

“…At the same time, the journal INTEGRATIVE CANCER THERAPIES published the most articles in this field. …”
Get full text

Variability of Reaction Time as a Marker of Executive Function Impairments in Fibromyalgia by Stefan Duschek, Cristina Muñoz Ladrón de Guevara, María José Fernández Serrano, Casandra I. Montoro, Santiago Pelegrina López, Gustavo A. Reyes del Paso

“…Optimized assessment may facilitate the personalization of therapies aimed at improving the cognitive function of those with the disorder.…”
Get full text

Patients' perceived needs for medical services for non-specific low back pain: A systematic scoping review. by Louisa Chou, Tom A Ranger, Waruna Peiris, Flavia M Cicuttini, Donna M Urquhart, Kaye Sullivan, Maheeka Seneviwickrama, Andrew M Briggs, Anita E Wluka

“…However, there was dissatisfaction with the cursory and superficial approach of care. (2) Patients had concerns about pharmacotherapy, with few studies reporting on patients' preferences for medications. (3) Of the few studies which examined the patients' perceived need of invasive therapies, these found that patients avoided injections and surgeries (4) Patients desired spinal imaging for diagnostic purposes and legitimation of symptoms.…”
Get full text

Key personal insights and changing needs of osteoarthritis patients: an international quantitative survey analysis by Zoltan Szekanecz, Diana Osadcii-Zaiat, András Bajkó, Hajnalka Minda, Dóra Szerencsés

“…Over-the-counter anti-inflammatory creams and prescription oral anti-inflammatory drugs are the most used therapies. The pandemic negatively affected OA symptoms. …”
Get full text

Research Progress on the Potential Pathogenesis of Persistent Postural–Perceptual Dizziness by Chen Qin, Ruyi Zhang, Zhihui Yan

“…Methods To better understand the pathogenesis of PPPD and to aid in the development of novel diagnostic strategies and therapies, we conducted a comprehensive narrative review of the relevant literature. …”
Get full text

Patient Experience of Living With Hemophilia A: A Conceptual Model of Humanistic and Symptomatic Experience in Adolescents, Adults, and Children by Zalmai Hakimi, Rakhee Ghelani, Linda Bystrická, Nana Kragh, Patrick Marquis, Jameel Nazir, Nadine McGale

“…**Conclusion:** Insights gathered through the interviews and resulting conceptual model support development of new therapies to address the physical and social challenges identified by PwHA and highlight a need for novel hemophilia A treatments that can ease treatment administration, provide adequate level of protection, and enable life to be lived normally.…”
Get full text

Towards culturally inclusive healthcare in Peru: Mapping epistemic concepts in contemporary Indigenous Amazonian medicine-Traditional healers' perspectives. by Ilana Berlowitz, Maria Amalia Pesantes, Cynthia Cárdenas Palacios, Chantal Martin-Soelch, Ursula Wolf, Caroline Maake

“…Our findings also highlight Amazonian healers' unique expertise around the therapeutic applications of psychoactives, from which the current revival of clinical scientific interest in psychedelic-assisted therapies may have a great deal to learn.…”
Get full text

Role of Ketamine in the Treatment of Psychiatric Disorders by Sahar Derakhshanian, Maxine Zhou, Alexander Rath, Rachel Barlow, Sarah Bertrand, Caroline DeGraw, Christopher Lee, Jamal Hasoon, Alan D. Kaye

“…Underlying disease processes are multifactorial and not well understood. Adjunctive therapies for TRD with proven benefits exist, but acutely depressed and suicidal patients often require prolonged inpatient stabilization. …”
Get full text

MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations by Athanasia Tsaousi, Ellen Witte, Katrin Witte, Hans-Joachim Röwert-Huber, Hans-Dieter Volk, Wolfram Sterry, Kerstin Wolk, Sylke Schneider-Burrus, Robert Sabat

Get full text

Evaluation of extracts from Phyllostachys makinoi for their antibacterial and accelerated wound healing potential by Te-Hua Liu, Ju-Yun Wu, Meng-Chun Cheng, Bang-Yuan Chen, Tsung-Yu Tsai

“…In conclusion, P. makinoi water and ethanol extracts demonstrated antibacterial and anti-inflammatory effects, showing potential for treating wound infections and accelerating healing, making them promising candidates for wound-healing therapies.…”
Get full text

Immediate-Early Genes and Delayed Primary Response Genes Regulated by NmU in SKBR3 HER-2 Positive Breast Cancer Cell Line by Jessica Murphy, Sweta Rani

“…Through further research, this could lead to the potential development of alternative therapies for HER2-positive breast cancer by targeting these genes.…”
Get full text

Patients’ Experiences of Living with Atrial Fibrillation: A Mixed Methods Study by Marie Stridsman, Anna Strömberg, Jeroen Hendriks, Ulla Walfridsson

“…Less attention has been paid to patient-related issues, such as understanding how symptoms, different therapies, and lifestyle adjustments affect daily life. …”
Get full text

Regulation of miRNAs in obesity and diabetes by Eva Maher, Ava O'Meara, Cathy Brougham

“…In order to enhance miRNA-based therapies, the miRNA expression profile of obesity and its related disorders must be monitored to further understand the underlying mechanisms of obesity and to identify novel targets. …”
Get full text

Magnetic resonance imaging in primates. The example of the mouse lemur (Microcebus murinus): From detection of pathological aging to therapeutic evaluations by Nelly Joseph-Mathurin, Olene Dorieux, Audrey Kraska, Anne Bertrand, Mathieu Santin, Nadine El Tannir El Tayara, Marc Dhenain

“…Rodents and particularly transgenic mice are widely used as models for research on physiopathology of cerebral aging, neurodegenerative diseases and for the evaluation of therapies. However these models do not mimic all the pathophysiological aspects of human diseases. …”
Get full text

A meta-analysis on the impact of concurrent or pre-existing cancer diagnosis on acute myocardial infarction outcomes. by Jie Wang, Jia Yu

“…Early interventions, such as close monitoring of cardiac function, lifestyle modifications, and targeted pharmacological therapies, might help mitigate the risk of AMI and improve overall clinical outcomes. …”
Get full text

A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis. by Courtney A Granville, Regan M Memmott, Andria Balogh, Jacopo Mariotti, Shigeru Kawabata, Wei Han, Jaclyn Lopiccolo, Jason Foley, David J Liewehr, Seth M Steinberg, Daniel H Fowler, M Christine Hollander, Phillip A Dennis

“…Because these mutations confer resistance to commonly used cytotoxic chemotherapies and targeted agents, effective therapies that target K-Ras are needed. Inhibitors of mTOR such as rapamycin can prevent K-Ras-driven lung tumorigenesis and alter the proportion of cytotoxic and Foxp3+ regulatory T cells, suggesting that lung-associated T cells might be important for tumorigenesis.…”
Get full text

Virtual Screening, Toxicity Evaluation and Pharmacokinetics of Erythrina Alkaloids as Acetylcholinesterase Inhibitor Candidates from Natural Products by Permana A, Akili AWR, Hardianto A, Latip JB, Sulaeman AP, Herlina T

“…Afri Permana,1 Abd Wahid Rizaldi Akili,1 Ari Hardianto,1 Jalifah Binti Latip,2 Allyn Pramudya Sulaeman,1 Tati Herlina1 1Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Padjadjaran, Sumedang, West Java, Indonesia; 2Department of Chemical Sciences, Faculty of Science and Technology, Universiti Kebangsaan Malaysia (UKM), Selangor, MalaysiaCorrespondence: Tati Herlina, Email tati.herlina@unpad.ac.idPurpose: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with limited treatment options, necessitating the development of safer and more effective therapies. The potential of alkaloids derived from the genus Erythrina as acetylcholinesterase (AChE) inhibitors is being investigated to enhance acetylcholine levels in the brain, which is crucial for the treatment of AD. …”
Get full text

Longitudinal Relationship between the Introduction of Medicinal Cannabis and Polypharmacy: An Australian Real-World Evidence Study by Maja Kalaba, Graham M. L. Eglit, Matthew T. Feldner, Patrizia D. Washer, Tracie Ernenwein, Alistair W. Vickery, Mark A. Ware

“…Recent studies recommend medicinal cannabis (MC) as a potential treatment for chronic pain (CP) when conventional therapies are not successful; however, data from Australia is limited. …”
Get full text

Impact of COPD and asthma on in-hospital mortality and management of patients with heart failure in England and Wales: an observational analysis by Claudia Gulea, Rosita Zakeri, Jennifer K Quint, Constantinos Kallis

“…COPD is associated with higher in-patient mortality and lower cardiology referral odds, while COPD and asthma are both associated with lower use of prognostic HF therapies on discharge. These data highlight therapeutic gaps and a need for better integration of cardiopulmonary services to improve healthcare provision for patients with HF and coexisting respiratory disease.…”
Get full text