Impact of Dienogest Alone or in Combination with Ethinylestradiol on the Quality of Life of Women with Endometriosis: A Prospective Cohort Study by Mujde Canday, Suleyman Salman

“…Following the guidelines accepted step therapy in treating mild or moderate endometriosis, cyclic oral contraceptives may be recommended as first-line therapy. …”
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Management of a Female Patient with Irritable Bowel Syndrome and Somatoform Disorder by E. A. Trush, E. A. Poluektova, A. G. Beniashvili, O. S. Shifrin

“…On discharge from hospital recommended cognitive-behavioral therapy, continue taking macrogol, as well as treatment with Kolofort. …”
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Hydrogel-based nanoparticles: revolutionizing brain tumor treatment and paving the way for future innovations by Alireza Shadab, Simin Farokhi, Arshia Fakouri, Neda Mohagheghzadeh, Ali Noroozi, Zahra Sadat Razavi, Arian Karimi Rouzbahani, Hamidreza Zalpoor, Mohamad Mahjoor

“…Abstract Brain tumor treatment remains a significant challenge due to their high mortality and resistance to current therapies. This paper discusses the promising potential of hydrogel-based nanoparticles as innovative drug delivery systems for brain tumor therapy. …”
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Analysis of Healthcare Resource Utilization and Costs after the Initiation of Biologic Treatment in Patients with Ulcerative Colitis and Crohn’s Disease by Sue Perera, Shibing Yang, Marni Stott-Miller, Joanne Brady

“…**Background:** This retrospective cohort study aimed to describe and quantify healthcare resource utilization and costs for patients with ulcerative colitis (UC) and Crohn’s disease (CD) following initiation of biologic therapy. **Methods:** Resource utilization and costs were analyzed at baseline and 1- and 2-years after initiating a biologic. …”
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Budget Impact Analysis of Treatment Flow Optimization in Epilepsy Patients: Estimating Potential Impacts with Increased Referral Rate to Specialized Care by Masaki Iwasaki, Takashi Saito, Akiko Tsubota, Tatsunori Murata, Yuta Fukuoka, Kazutaka Jin

“…However, important information in the decision-making such as transition probability to the next therapy or excuse for sensitive limitations is not available currently. …”
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GIANT CELL TUMOR OF THE RIBS: A CASE REPORT by I Putu Gede Pradnyadewa Pradana, Mouli Edward

“…Discussion: An unusual location of GCT lesions needs to be a concern because they can be underdiagnosed not to receive optimal therapy. Inadequate therapy can increase the incidence of recurrence and malignancy changes. …”
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Retrospective Analysis of Healthcare Resource Use, Treatment Patterns, and Treatment-related Events in Patients with Huntington’s Disease–associated Chorea Initiated on Tetrabenazi... by Victor W. Sung, Sanjay K. Gandhi, Victor Abler, Brian Davis, Debra E. Irwin, Karen E. Anderson, Ravi G. Iyer

“…A total of 41.8% (59/141) of HD patients who initiated tetrabenazine experienced a ≥60-day gap in tetrabenazine therapy, with a median time to discontinuation of 293.5 days. …”
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Dyslipidemias in normotensive and hypertensive individuals by NM Igboh, D Onwubiko, LN Chigbu, CI Emuchey, NK Nnamah, CA Onyesom, EN Agomuo, CA Maduagwuna, KME Iheanacho

“…:The present work was carried out to compare the effects of age and antihypertensive therapy on lipid profile in hypertensive and normotensive individuals. …”
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1+(no)1=3, and more by Carmen García

“…While  an approach to transformational change through paradoxical thinking and the creativity of the absurd is not new, it doesn’t seem to have produced news of difference, since binary thinking seems to persist, with ethical implications for the praxis of systemic therapy and its education and training. Indeed, binary mapping, even when critiqued, tends to reinforce itself, creating a strange loop similar to a Moebius strip. …”
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Chronic glomerulonephritis of the mixed type in patient with HBV-infection (<i>Clinical case</i>) by V. S. Adonyeva, A. B. Botchkarev, O. S. Saurina

“…Patients with renal involvement within the framework of chronic НВV-infection require antiviral therapy by nucleoside analogues, their high antiviral activity is demonstrated by presented clinical case.…”
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ErbB- and MUC1-targeted CAR-T cell immunotherapy of oral squamous cell carcinoma by Saffron E. Summers, Saffron E. Summers, Vehid Salih, Andrew D. Foey

“…Chimeric antigen receptor T (CAR-T) cell therapy has shown great success in treating B cell malignancies; however, there are many challenges that limit their therapeutic efficacy in solid tumours. …”
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Economic Evaluation of Fidaxomicin for the Treatment of Clostridium Difficile Infection (C. difficile-associated diarrhoea) in Ireland by Anke van Engen, Montserrat Casamayor, Fidelma Loftus, Martin Coen, Andy Garnham, Maureen Watt, Larry Lacey

“…**Results:** In the base case, fidaxomicin was dominant to current standard-of-care therapy, with cost savings of €2,904 and incremental quality-adjusted life year (QALY) gain of 0.031. …”
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Recent advances in nanomaterials and their mechanisms for infected wounds management by Jianping Zhu, Fan Xia, Shuaifei Wang, Yan Guan, Fuqiang Hu, Fangying Yu

“…The antibacterial mechanisms of nanomaterials are varied, including ion release, chemodynamic therapy, photothermal/photodynamic therapy, electrostatic interactions, and delivery of antibacterial drugs, which not only combat bacterial infections but also address the challenges posed by biofilms and antibiotic resistance. …”
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Incremental Healthcare Costs and Outpatient Antifungal Treatment of Patients with Aspergillosis in the United States by Emily Durden, Donna McMorrow, Paul Juneau, Robert Fowler, Paresh Chaudhari, David Horn

“…Outpatient antifungal therapy and total and outpatient healthcare resource utilization were evaluated in the post-index period. …”
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TUBERCULOUS ARTHRITIS OF THE ANKLE MIMICKING SYNOVITIS IN CHILD - A CASE REPORT by Erick Yudistira Christanto, Sulis Bayusentono

“…Anti-tuberculous drugs (ATD) therapy was given with isoniazid 50 mg, rifampicin 75 mg, pyrazinamide 150 mg, and ethambutol 230 mg for two months, as an intensive phase therapy following rifampicin 75 mg and isoniazid 50 mg for ten months. …”
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Optimizing the Future: A Game Theory to Tumor Therapeutic Strategies by Fang-Yuan Liu, Xin Liu, Dan-Ni Ding, Shao-Xuan Liu, Jing Xu, Yu-Xin Zhao, Yan-Hong Wang, Feng-Juan Han

“…Conversely, in cases where the proliferation ability of malignant tumors is weak, the dosage of chemotherapy and the adjuvant therapy with Chinese medicine should be kept in a relatively balanced state. …”
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Gastric Polyps and Atrophic Gastritis by I. Yu. Kolesnikova, A. S. Novikova

“…The H. pylori eradication, in contrast to anti-secretory therapy, allows the containment of chronic gastritis and is a critical measure in gastric cancer prevention.…”
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Informal gold miners with mercury toxicity: Novel asymmetrical neurological presentations by J George, E Sadiq, I Moola, S Maharaj, A Mochan

“…Patient 1 responded well to chelation therapy, but patient 2 refused admission and further medical treatment. …”
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Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections? by Mieke A. van der Mescht, Helen C. Steel, Ronald Anderson, Theresa M. Rossouw

“…The currently available anti-VEGF therapy strategies target the binding of VEGF-A to both VEGFR-1 and VEGFR-2. …”
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Emerging insights into intravital imaging, unraveling its role in cancer immunotherapy by Minfeng Yang, Shiqiang Hou, Yao Chen, Hongzhao Chen, Minjie Chu, Song-Bai Liu

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