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Immunogenic dying cells elicit potent anti-tumor T cell immunity against lung metastasis and tumorigenesis
Published 2025-01-01“…We immunized mice with ICD dying tumor cells in prevention, therapy in lung metastasis models, and Gprc5a-knockout (ko) model of lung tumorigenesis. …”
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Managing anxiety disorders with the neuro-biofeedback method of Brain Boy Universal Professional
Published 2022-05-01“… # Conclusion Both HAMA-A and SAS scales showed statistically reduced anxiety levels after biofeedback therapy. Thus, the primary symptom of anxiety can be addressed by the biofeedback method.…”
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864
From economics to health outcomes: Delving into the significance of reduced insulin prices
Published 2024-08-01“… The recent substantial price reductions in insulin therapy by major manufacturers prompt an examination of their impact on South Africa (SA)’s healthcare. …”
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Pharmacogenetic markers of colorectal cancer treatment. New approaches for cytostatic drugs efficacy estimation
Published 2015-12-01“…To analyze and present data of the foreign pharmacogenetic studies devoted to improvement of pharmacological therapy of colorectal cancer (CRC), in particular those, focused on the drugs with general cytostatic action: 5-fluorouracil derivatives, irinotecan and platinum agents.Summary. …”
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867
Russian interferon <i>α</i>-2b drug in the treatment of chronic hepatitis C
Published 2014-08-01“…The registered adverse effects, well-known for interferon α-2b therapy, as a rule, were mild or moderate, AVT cancellation was not required in any patient.Conclusions. …”
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868
Update on Helicobacter pylori infection study and key points of «Maastricht-V» consensus conference (2016)
Published 2018-08-01“…Association of H. pylori to both gastroenterological and non-gastrointestinal diseases and optimization of eradication therapy modes were discussed at the consensus conference. …”
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869
Basic Molecular Biology, Metabolic and Immunological Mechanisms of Fecal Microbiota Transplantation
Published 2024-12-01“…This complication required resumption and subsequent intensification of immunosuppressive therapy with complete resolution of GVHD symptoms. …”
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Options of improvement of efficacy of gastroesophageal reflux disease treatment by dioctaedric smectite
Published 2015-10-01“…On a background of therapy by PPI + Smecta acidic refluxes have been eliminated in 14 (93%), at PPI monotherapy — in 11 (73%), at Smecta monotherapy — in 100% of patients. …”
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CD36 inhibition enhances the anti-proliferative effects of PI3K inhibitors in PTEN-loss anti-HER2 resistant breast cancer cells
Published 2025-02-01“…Abstract Background HER2-positive patients comprise approximately 20% of breast cancer cases, with HER2-targeted therapy significantly improving progression-free and overall survival. …”
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Angiopoietin-2 and D-dimer add prognostic information to clinical risk in pulmonary arterial hypertension
Published 2025-02-01“…Results: Angiopoietin-2 levels were elevated and fell in response to effective therapy (drop in Reveal Lite 2 score). At follow-up, persistently elevated angiopoietin-2 levels predicted clinical events and even identified low-risk participants who subsequently had events. …”
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Synergistic strategies for glioblastoma treatment: CRISPR-based multigene editing combined with immune checkpoint blockade
Published 2025-02-01“…This research introduces a promising universal platform for combining immune checkpoint blockade therapy with gene editing treatment. Graphical Abstract…”
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Elexacaftor/tezacaftor/ivacaftor and inflammation in children and adolescents with cystic fibrosis: a retrospective dual-center cohort study
Published 2025-02-01“…Laboratory data of a control group (pwCF, not in ETI therapy, same demographic characteristics as the study group) were also collected. …”
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Targeting CXCL8 signaling sensitizes HNSCC to anlotinib by reducing tumor-associated macrophage-derived CLU
Published 2025-02-01“…Abstract Background Although nutrition-starvation therapy for malignancies such as HNSCC is highly desirable, the clinical outcomes remain disappointing. …”
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Conditioned medium derived from mesenchymal stem cells and spinal cord injury: A review of the current therapeutic capacities
Published 2025-06-01“…However, achieving an effective therapy with the minimum side effects for SCI is still a puzzle. …”
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The Psychological Impact of Amblyopia Treatment: A Systematic Literature Review
Published 2025-01-01“…School-aged children and those receiving occlusion therapy in the form of patching report higher distress than infants and young-children, and those receiving atropine occlusion therapy or refractive correction only. …”
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Prevention and treatment of cerebral vasospasm following aneurysmal subarachnoid hemorrhage
Published 2023-12-01“…Future trials of these therapies and combinations of existing therapies are needed, and functional outcomes should be included as an endpoint. …”
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Thrombotic Complications in Inflammatory Bowel Disease
Published 2019-05-01“…Taking into account the pathogenetic factors, the following options are possible in the prevention and treatment of thrombotic complications in IBD: strengthening the basic therapy of the primary disease; administration of prophylactic doses of anticoagulants under dynamic continuous laboratory control in the acute period using the methods of conservative therapy of thrombotic complications (elastic compression of the lower extremities) in the period of exacerbation of the primary disease.…”
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