An Unusual Case of Ototoxicity with Use of Oral Vancomycin by Umut Gomceli, Srija Vangala, Cosmina Zeana, Paul J. Kelly, Manisha Singh

“…A 42-year-old woman with a history of hypertension, diabetes mellitus, and previously treated Clostridium difficile colitis presented with abdominal pain and diarrhea for two weeks. Clostridium difficile infection was confirmed by PCR, and at the time of diagnosis and initiation of therapy, the patient had normal renal function. …”
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The effect of educational intervention through sending emails on improving physical posture in female computer users of Eastern Iran: a quasi-experiment study by Zahra Hosseini, Arash Ziapour, Arash Ziapour, Seyyede Fateme Rahimi, Fatemeh Dalake, Murat Yıldırım, Murat Yıldırım

“…A training program was developed on the ergonomics of office work (12 emails at an interval of 6 weeks). The data was collected using demographic, occupational information, and a knowledge assessment questionnaire. …”
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Determining the impact of mobile-based self-care applications on reducing anxiety in healthcare providers: a systematic review by Mohammad Mahdi Askarizadeh, Leila Gholamhosseini, Reza Khajouei, Saeedeh Homayee, Fatemeh Askarizadeh, Leila Ahmadian

“…Results Based on the results, studies were conducted in nine different countries, and the intervention duration and strategies for reducing anxiety using self-care applications ranged from two weeks to four months. The impact of mobile health applications, their content, and intervention strategies on reducing anxiety were positive. …”
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Laser Based ¹³C-urea Breath Test in Quantitative Assessment of Bacterial Colonization, Severity of Inflammation and Atrophy in Gastric Mucosa by E. V. Stepanov, V. T. Ivashkin

“…The 13C-UBT DLS was performed in 525 patients before the start of eradication therapy and in 196 patients 10–12 weeks after its completion. The breath test was carried out according to a standard protocol using the BSIA patent kit (Great Britain). …”
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Is platelet-rich plasma better than steroids as epidural drug of choice in lumbar disc disease with radiculopathy? Meta-analysis of randomized controlled trials by Sathish Muthu, Sathish Muthu, Sathish Muthu, Vibhu Krishnan Viswanathan, Vibhu Krishnan Viswanathan, Prakash Gangadaran, Prakash Gangadaran, Prakash Gangadaran

“…The included studies compared the efficacy and safety of epidural PRP and steroids at various time-points including 1, 3, 6, 12, 24, and 48 weeks. Epidural PRP injection was found to offer comparable pain relief (VAS; WMD = −0.09, 95% CI [−0.66, 0.47], p = 0.641; I2 = 96.72%, p < 0.001), functional improvement (ODI; WMD = 0.72, 95% CI [-6.81, 8.25], p = 0.524; I2 = 98.73%, p < 0.001), and overall health improvement (SF-36; WMD = 1.01, 95% CI [−1.14, 3.17], p = 0.224; I2 = 0.0%, p = 0.36) as epidural steroid injection (ESI) at all the observed time points in the included studies without any increase in adverse events or complications. …”
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Chronic inflammation in post-acute sequelae of COVID-19 modulates gut microbiome: a review of literature on COVID-19 sequelae and gut dysbiosis by Najeeha Talat Iqbal, Hana Khan, Aqsa Khalid, Syed Faisal Mahmood, Nosheen Nasir, Iffat Khanum, Isadora de Siqueira, Wes Van Voorhis

“…Most studies define Long COVID, through symptoms like fatigue, brain fog, joint pain, and headache prevailing four or more weeks post-initial infection. Global variations in Long COVID presentation and symptoms make it challenging to standardize features of Long COVID. …”
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Efficacy of Curcumin on Treating Cancer Anorexia-Cachexia Syndrome in Locally or Advanced Head and Neck Cancer: A Double-Blind, Placebo-Controlled Randomised Phase IIa Trial (CurCh... by Tawasapon Thambamroong, Kasan Seetalarom, Siriwimon Saichaemchan, Yanisa Pumsutas, Naiyarat Prasongsook

“…Twenty patients with CAS in locally advanced or advanced head and neck cancer adequately nourished via a feeding tube were enrolled and randomised in a 1 : 1 ratio to receive oral curcumin (at a dose of 4000 mg daily) (n = 10) or placebo (n = 10) for 8 weeks. The primary endpoint was body composition (muscle mass, body fat mass, and basal metabolic rate). …”
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Effect of soluble dietary fiber extracted from Lentinula edodes (Berk.) Pegler on lipid metabolism and liver protection in mice on high-fat diet by Kangxiao Guo, Kangxiao Guo, Jing Liu, Zihan Yao, Zhoujin Tan, Tao Yang

“…Project team from Lentinus edodes extracted soluble dietary fiber, and its physicochemical properties, selected 30 male mice, randomly divided into normal group (N), high fat diet group (F), add low dose dietary fiber high fat diet (FL), add medium dose dietary fiber high fat diet group (FM), add high dose dietary fiber high fat diet group (FH) five groups. After 4 weeks, we assessed general state, organ conditions, liver status, blood parameters, expression of hepatic lipid metabolism genes, mRNA levels of key hepatic lipid metabolism genes. …”
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Spatial proteomics identifies a CRTC-dependent viral signaling pathway that stimulates production of interleukin-11 by Benjamin J. Ravenhill, Marisa Oliveira, George Wood, Ying Di, Joanne Kite, Xinyue Wang, Colin T.R. Davies, Yongxu Lu, Robin Antrobus, Gill Elliott, Nerea Irigoyen, David J. Hughes, Paul A. Lyons, Betty Chung, Georg H.H. Borner, Michael P. Weekes

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Does macrolide use confer risk of out-of-hospital cardiac arrest compared with penicillin V? A Danish national case-crossover and case–time–control study by Lars Køber, Freddy Lippert, Charlotte Andersson, Peter E Weeke, Gunnar H Gislason, Frederik Boetius Hertz, Aksel Jensen, Jenny D Knudsen, Magnus Arpi, Christian Torp–Pedersen

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Voriconazole Pharmacokinetics Administered at 4 mg/kg IM and IV in Nursehound Sharks (<i>Scyliorhinus stellaris</i>) Under Human Care by Daniela Cañizares-Cooz, Daniel García-Párraga, Sonia Rubio-Langre, Teresa Encinas, Pablo Morón-Elorza

“…No adverse effects were detected during the study or four weeks after administration. These results support the administration of IV and IM voriconazole in sharks; however, additional studies on toxicity and pharmacodynamics are necessary. …”
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Twelve-Month Retention in and Impact of Enhance®Fitness on Older Adults in Hawai‘i by Michiyo Tomioka, Kathryn L. Braun, Yan Yan Wu, Kay Holt, Paula Keele, Lori Tsuhako, Johnny Yago

“…On average, participants attended 63.7% of thrice-weekly classes each month. Participants’ physical performance measures improved after 4 months, continued to improve until 8 months, and were maintained thereafter. …”
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Impact of COVID-19 restrictions on behavioural and psychological symptoms in home-dwelling people with dementia: a prospective cohort study (PAN.DEM) by Maarja Vislapuu, Mala Naik, Bettina S Husebø, Marie H Gedde, Ipsit V Vahia, Janne Mannseth, Line I Berge

“…Objectives To investigate the impact of the COVID-19 restrictions on behavioural and psychological symptoms of dementia (BPSD).Design Prospective cohort study (PAN.DEM) nested within the halted parent trial (LIVE@Home.Path).Setting Households in Norway immediate before and 6–9 weeks into the COVID-19 restrictions.Participants 104 dyads (persons with mild to moderate dementia aged ≥65 and their informal carers) completed both prepandemic and pandemic assessments, among 237 in the parent trial. …”
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Pengaruh Pemijatan Perineum pada Primigravida terhadap Kejadian Ruptur Perineum saat Persalinan di Bidan Praktek Mandiri di Kota Bengkulu Tahun 2014 by Wewet Savitri, Ermawati ., Elda Yusefni

“…The study was conducted in independent practice of midwifery) in Bengkulu city including subject of 28 primigravida with 36 weeks of gestation consisting of 14 intervention group and 14 control group. …”
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Short-Term Efficacy of Using a Novel Low-Volume Bone Marrow Aspiration Technique to Treat Knee Osteoarthritis: A Retrospective Cohort Study by Daniel Kuebler, Alexandra Schnee, Lisa Moore, Jason Kouri, Alexis McLaughlin, Robert Hanson, Patrick Kuebler, Ignacio Dallo, Alberto Gobbi

“…In addition, the PGIC scores measuring patient satisfaction improved from 4.03±0.26 at 6 weeks postprocedure to 4.65±0.28 at 6 months postprocedure (p<0.0001). …”
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Development and validation of a nomogram for predicting cough variant asthma diagnosis by Jiao Min, Xiaomiao Tang, Di Zhang, Jin Yang, Fei Li, Wei Lei

“…Methods We conducted a retrospective review of clinical data from 241 outpatients with chronic cough (≥ 8 weeks) who underwent bronchial provocation test at our hospital between January 2018 and December 2021. …”
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Ozone Therapy on Rats Submitted to Subtotal Nephrectomy: Role of Antioxidant System by José Luis Calunga, Zullyt B. Zamora, Aluet Borrego, Sarahí del Río, Ernesto Barber, Silvia Menéndez, Frank Hernández, Teresita Montero, Dunia Taboada

“…Renal function was evaluated, as well as different biochemical parameters, at the beginning and at the end of the study (10 weeks). Renal plasmatic flow (RPF), glomerular filtration rate (GFR), the urine excretion index, and the sodium and potassium excretions (as a measurement of tubular function) in the ozone group were similar to those in Sham group. …”
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Study on the protective effect of naringin-regulated lncRNA GAS5 against mitochondrial apoptosis in osteoarthritic chondrocytes by LIN Qin, ZHU Yingkai, LIN Yanming, LAN Shujie, CHEN Changxing, FU Changlong

“…ObjectiveTo investigate the protective effect of naringin on mitochondrial apoptosis in osteoarthritic (OA) chondrocytes by regulating lncRNA GAS5.MethodsIn vivo experiments, a rat OA model was constructed using the modified Hulth method and treated with naringin at 70 mg/kg by gavage for 8 weeks. Magnetic resonance imaging and ultrasound were used to identify the success of modeling; histopathological changes in rat articular cartilage were assessed using toluidine blue and saffron O staining; changes in the levels of lncRNA GAS5 in rat cartilage tissues after naringin intervention were detected by Real-time PCR; Western blot detected Caspase-3, Bax, MMP-13 and Cyt-C in rat cartilage tissues. …”
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Argonaute2 and Argonaute4 Involved in the Pathogenesis of Kawasaki Disease via mRNA Expression Profiles by Zon-Min Lee, Hui-Chuan Chang, Shih-Feng Liu, Ying-Hsien Huang, Ho-Chang Kuo

“…The Human Transcriptome Array (HTA 2.0) analysis included 50 children with KD prior to IVIG (KD1), 18 children with KD three weeks post-IVIG (KD3), 18 non-febrile controls (HC), and 18 febrile controls (FC), which were arranged in the quoted publications for all materials and methods in order to collect data. …”
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Knowledge and perception of stroke management practices among middle-aged residents of Otolo community in Nnewi North Local Government Area, Nigeria by Uchenna Prosper Okonkwo, Chidera Chibuikem Fortunate, Sochima Johnmark Obiekwe, Uchechukwu Martha Chukwuemeka, Christiana Nkiru Okafor, Augustine Asiduba Igwe, Jovita Ada Daniel

“…The data collection lasted for four weeks and it took the average of 12 min to complete each questionnaire. …”
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