Hydrogen-oxygen mixture inhalation as an adjunctive treatment to home-based exercise in older patients with knee osteoarthritis: an open-label, blinded-endpoint, randomized control... by Chenhui Wang, Mengwei Yan, Yuru Li, Lei Han, Hongqian Wang, Shufeng Jia, Xingchen Liu, Yang Liu, Fan Wu, Baoguo Wang

“…Both groups participated in a 12-week home-based exercise (HBE) program, which included knee-joint exercises and health education. …”
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Vagal Blocking Improves Glycemic Control and Elevated Blood Pressure in Obese Subjects with Type 2 Diabetes Mellitus by S. Shikora, J. Toouli, M. F. Herrera, B. Kulseng, H. Zulewski, R. Brancatisano, L. Kow, J. P. Pantoja, G. Johnsen, A. Brancatisano, K. S. Tweden, M. B. Knudson, C. J. Billington

“…Effects on weight loss, HbA1c, fasting blood glucose, and BP were evaluated at 1 week to 12 months. Results. 26 subjects (17 females/9 males, 51±2 years, BMI 37±1 kg/m2, mean ± SEM) completed 12 months followup. …”
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Transcutaneous electrical acupoint stimulation for hypertension complicated by anxiety or sleep disorders: A pilot randomized controlled trial by Xue-Ying Bao, Cun-Zhi Liu, Zi-Tong Qian, Lu Wang, Jian-Feng Tu, Bin-Yan Li, Xiao Wang, Fang Wan, Zhi-Han Li, Zhao-Yi Liu, Liang-Xiao Ma, Li-Qiong Wang

“…The primary outcome was the change in office systolic blood pressure from baseline to week four. Secondary outcomes included changes in office diastolic blood pressure, heart rate, Pittsburgh Sleep Quality Index score, and Generalized Anxiety Disorder 7-item scale score from baseline to week four. …”
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Bexarotene-induced hypothyroidism and dyslipidemia; a nation-wide study by Katsunori Manaka, Junichiro Sato, Yusuke Hikima, Hirofumi Horikoshi, Maho Taguchi, Akimichi Morita, Hiraku Suga, Hikari Boki, Taku Fujimura, Yoji Hirai, Takatoshi Shimauchi, Chiharu Tateishi, Eiji Kiyohara, Ikko Muto, Hideki Nakajima, Riichiro Abe, Kazuyasu Fujii, Chikako Nishigori, Eiji Nakano, Kentaro Yonekura, Takeru Funakoshi, Masahiro Amano, Tomomitsu Miyagaki, Reiko Yamashita, Makoto Sugaya, Toshihisa Hamada, Masaomi Nangaku, Taroh Iiri, Noriko Makita

“…Additionally, one-third of grade ≥3 AEs on hypertriglyceridemia occurred within 1 week. The delta_FT4 (difference in FT4 from baseline) negatively correlated with TG increase at 1 week (p = 0.012) but not with low density lipoprotein cholesterol (LDL-C) increase at any week. …”
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Reflections by Joanne Embree

“…It didn't get done that night or during the next week. Somehow, the topic that I had originally chosen just didn't seem that important anymore as I, along my friends and colleagues, reflected on the changes that the events of that day were likely to have on our lives.…”
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A Randomized Trial to Evaluate the Sustained Efficacy of a Mucus Clearance Device in Ambulatory Patients with Chronic Obstructive Pulmonary Disease by Norman Wolkove, Marc A Baltzan, Hany Kamel, Michael Rotaple

“…OBJECTIVE: To determine whether a mucus clearance device (MCD) (Flutter; Axcan Scandipharm, USA) could consistently improve the bronchodilator response and exercise performance in patients with chronic obstructive pulmonary disease (COPD) when used in an ambulatory setting over a one-week period.…”
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Healthy Living: Tips for Staying Regular by Linda B. Bobroff

“…Constipation means having a bowel movement fewer than three times a week. Stools are usually hard and can be painful to pass. …”
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Epidermoid Carcinoma of the Cervix and Pregnancy. A case presentation. by Práxedes Rojas Quintana, Doris González Díaz, Carlos Pérez Velásquez

“…<p>A 25 year-old female patient with a 12 week pregnancy was presented. She was diagnosed with an ultered Pap test. …”
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Ticagrelor Associated Heart Block: The Need for Close and Continued Monitoring by Munish Sharma, Daniel A. N. Mascarenhas

“…According to the PLATO trial, ticagrelor is associated with ventricular pauses in the first week of treatment; however, these episodes were felt to be asymptomatic and nonfatal to the patient. …”
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La junte militaire birmane confrontée au Cyclone Nargis by Marion Sabrié

“…Despite this disaster, the junta maintained the referendum about Constitution one week after.…”
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Septicemia and Aortic Valve Endocarditis due to Erysipelothrix rhusiopathiae in a Homeless Man by Dean Campbell, Mark Cowan

“…He recovered completely after aortic valve replacement and a 6-week course of intravenous ceftriaxone.…”
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Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction by Zhendong Feng, Han Xue Jiang, Huiyang Chen, Yu Ning Liu, Yahui Wang, Rui Bing Yang, Xueting Han, Chen Hui Xia, Ze Bing Zhu, Hongcai Shang, Aiming Wu, Wei Jing Liu

“…At week 4, LC3-II did not significantly increase and p62 levels significantly increased. …”
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Safety and efficacy of filgotinib in patients with rheumatoid arthritis: final results of the DARWIN 3 long-term extension study by Arthur Kavanaugh, Paul Emery, René Westhovens, Mark C Genovese, Kevin L Winthrop, Rieke Alten, Dick de Vries, Lorenzo Dagna, Patrick Verschueren, Maria Greenwald, Regina Cseuz, Robin Besuyen, Vikas Modgill, Ly Huong Le

“…Disease response assessed using non-responder imputation plateaued at LTE week 12 before slowly declining over time, with overall American College of Rheumatology (ACR)20/50/70 response rates of 26.9%/20.2%/14.7% at week 396.Conclusion Filgotinib was well tolerated in patients with RA for up to 8 years. …”
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Prevention Of Breast and Endometrial cancer using Total Diet Replacement (PROBE-TDR) trial: protocol for a randomised controlled trial by Robert Clarke, Emma J Crosbie, Basil G Issa, John Belcher, Helen Clarke, Anthony Howell, Michelle Harvie, Hannah Harrison, Cheryl Lombardelli, Suzanne Krizak, Katharine Sellers, Yit Y Lim, Caroline Parkin, Shruthi Patel, Anthony J Maxwell, Julie Wisely, Sacha J Howell

“…The TDR programme includes an initial 12-week period of TDR (850 kcal/day) followed by a 40-week food-based diet, based on the nutritional principles of a Mediterranean diet, as either continued weight loss (~1500 kcal/day) or weight loss maintenance (~2000 kcal/day). …”
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Correlates of and changes in aerobic physical activity and strength training before and after the onset of COVID-19 pandemic in the UK: findings from the HEBECO study by Lion Shahab, Abigail Fisher, Phillippa Lally, Aleksandra Herbeć, Dimitra Kale, Verena Schneider

“…MVPA increased or decreased by an average of 150 min/week and 219 min/week, respectively, and MSA by 2 days/week. …”
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Effectiveness of a Web-Based Medication Education Course on Pregnant Women’s Medication Information Literacy and Decision Self-Efficacy: Randomized Controlled Trial by Suya Li, Hui-Jun Chen, Jie Zhou, Yi-Bei Zhouchen, Rong Wang, Jinyi Guo, Sharon R Redding, Yan-Qiong Ouyang

“…A total of 108 participants were randomly divided into a control group (CG), which received routine prenatal care from nurses and physicians, and an intervention group (IG), which received an additional 3-week web-based medication education course based on the theory of planned behavior as part of routine prenatal care. …”
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Corneal Backscatter Analysis by In Vivo Confocal Microscopy: Fellow Eye Comparison of Small Incision Lenticule Extraction and Femtosecond Laser-Assisted LASIK by Alper Agca, Engin Bilge Ozgurhan, Yusuf Yildirim, Kadir Ilker Cankaya, Nimet Burcu Guleryuz, Zeynep Alkin, Abdullah Ozkaya, Ahmet Demirok, Omer Faruk Yilmaz

“…The mean backscattered light intensity (LI) at all measured depths and the maximum backscattered LI were higher in the SMILE group than the femto-LASIK group at all postoperative visits. LI differences at 1 week and 1- and 3-month visits were statistically significant (P<0,05). …”
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Levels of IL-6 and IL-1β in Umbilical Cord Blood in Relation to Mode of Birth by Ebru Aslan Patlakoğlu, Sündüz Özlem ALTINKAYA, Mustafa Uğur, Cuma Taşın, Nezaket Kadıoğlu

“…Also maternal age, gestational week, birth weight and body mass index did not correlate with cord blood cytokine levels. …”
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Claudin-4 Undergoes Age-Dependent Change in Cellular Localization on Pig Jejunal Villous Epithelial Cells, Independent of Bacterial Colonization by J. Alex Pasternak, Coral Kent-Dennis, Andrew G. Van Kessel, Heather L. Wilson

“…In the present study, FcRn gene (FCGRT) was minimally expressed in 6-week-old gut and newborn jejunum but it was expressed at significantly higher levels in the ileum of newborn piglets. pIgR was highly expressed in the jejunum and ileum of 6-week-old animals but only minimally in neonatal gut. …”
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The impact of genetic polymorphisms of IL28B gene on the efficacy of antiviral therapy of the chronic hepatitis C by using the standard Interferon-<i>α</i> by A. V. Lapshin, M. V. Mayevskaya, V. T. Ivashkin, P. O. Bogomolov, I. G. Nikitin, O. O. Znoyko

“…The study of IL28B genetic polymorphisms was conducted in 66 patients with HCV who did not receive the treatment earlier. The 24- week or 48-week antiviral therapy by standard Interferon-α2b and Ribavirin was prescribed to all patients, taking into consideration the genotype of the HCV-infection. …”
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