Showing 45,661 - 45,680 results of 45,950 for search '"The Times"', query time: 0.20s Refine Results
  1. 45661

    Les réseaux d’alimentation en eau des pentes de la Croix-Rousse et de la presqu’île de Lyon by Jules Ramona

    Published 2023-12-01
    “…It is also demonstrates for the first time in Lyon the existence of a hybrid lead-wood adduction system.The frequent presence of metal sockets under the outdoor spaces prompts us to consider the widespread use of this type of water supply in a public context. …”
    Get full text
    Article
  2. 45662

    Intrathecal Clonidine versus Dexmedetomidine as Adjuvants to Hyperbaric Ropivacaine in Lower Limb Orthopaedic Surgeries: A Randomised Clinical Study by Priya Kishnani, Aiman Monaf, Kalpesh Pati, Jatin Patel, Sara Mary Thomas

    Published 2025-02-01
    “…Results: The mean for age in Group RD5 was 39.43±10.6 years and Group RC30 was 41.43±13.65 years. The time to S2 regression was longer in Group RD5 (136.10±8.10 min) compared to Group RC30 (102.67±7.69 min) (p<0.0001). …”
    Get full text
    Article
  3. 45663

    L’infanticide féminin en question chez les Gaulois du Midi : l’apport des analyses ADN sur les nouveau-nés enterrés dans les habitats de l’âge du Fer by Bernard Dedet, Henri Duday, Philippe Gruat, Mélanie Pruvost

    Published 2022-12-01
    “…These perinatal burials in houses and their immediate surroundings, do not, however, appear to fill the gap represented by the overall absence of deceased persons from this age group within the necropolises of the region at this time. The significantly variable density of these findings, depending on the site, as well as the nearly total absence of infants of a few months of age, in both the houses and necropolises, suggest that other solutions must have existed, located both outside village limits, as well as outside of the cemeteries. …”
    Get full text
    Article
  4. 45664

    „O pecunia totius mali regina, fraudis et doli amica...“ Peníze v kultuře středověku by Tomáš Krejčík

    Published 2010-07-01
    “…Christianity had a positive relationship towards money, and the first Christians accepted it as a normal part of life. Money at that time served as a kind of medium, the images on which disseminated a substantial ideology in society, which succumbed to the power of these images. …”
    Get full text
    Article
  5. 45665

    Elevated D-dimer on admission may predict poor prognosis in childhood influenza associated encephalopathy by Huizhen Wang, Lingkong Zeng, Xingfeng Cheng, Hui Li, Hong Zhang, Yuanmei Shi, Yong Zhang, Changjian Li

    Published 2025-01-01
    “…In the univariate analysis, the poor prognosis group compared with the clinically cured group showed a significant increase in the number of days of hospitalization (3.0 vs. 9.5 days, P < 0.001), high-sensitivity C-reactive protein (6.80 vs. 1.88 mg/L, P = 0.003), interleukin-6 (20.26 vs. 8.24 pg/mL, P = 0.001), interleukin-10 (11.75 vs. 4.72 pg/mL, P = 0.003), alanine aminotransferase (104.0 vs. 20.0 U/L, P = 0.011), aspartate azelotransferase (186.5 vs. 37.0 U/L, P = 0.003), serum albumin (37.99 vs. 40.76 g/L, P = 0.042), prothrombin time (13.2 vs. 11.4 s, P = 0.017), D-dimer (4.34 vs. 0.44 mg/L FEU, P < 0.001), peripheral blood CD19 B-cell count (35.11 vs. 32.75 cells/µL, P = 0.018), and cerebrospinal fluid chloride (126.82 vs. 125.50 mmol/L, P = 0.027) were statistically different in the above 11 indicators. …”
    Get full text
    Article
  6. 45666

    <i>Pleurotus ostreatus</i>: Nutritional Enhancement and Antioxidant Activity Improvement Through Cultivation on Spent Mushroom Substrate and Roots of Leafy Vegetables by Eirini-Maria Melanouri, Ilias Diamantis, Marianna Dedousi, Eleni Dalaka, Paraskevi Antonopoulou, Seraphim Papanikolaou, Ioannis Politis, Georgios Theodorou, Panagiota Diamantopoulou

    Published 2025-01-01
    “…Afterwards, mushroom cultivation was conducted in bags, where production characteristics like earliness (the time from substrate inoculation to first harvest) and biological efficiency (BE %, the ratio of fresh mushroom weight to dry substrate weight × 100) were examined. …”
    Get full text
    Article
  7. 45667

    Five-Year Prospective Follow-Up of Patients with Hepatitis C Virus Infection Treated with Direct-Acting Antiviral Agents by Zhang Y, Xia H, Fan L, Jiang L, Yang B, Wang F

    Published 2025-01-01
    “…The proportion of all participants with undetectable HCV-RNA exceeded 98% at all follow-up time points. Patients experienced virological relapse, HCC, death and disease progression with a cumulative AIRs of 1.03% (95% confidence interval [CI] 0.6– 1.5), 1.76% (95% CI 1.2– 2.3), 1.51% (95% CI 1.0– 2.0), and 5.81% (95% CI 4.8– 6.8), respectively. …”
    Get full text
    Article
  8. 45668

    Assessment of Lower Limb Muscle Volume Using 3D Ultrasonography: Validity and Reliability Compared to MRI by Paul Ritsche, Romina Ledergerber, Michele Pansini, Francesco Santini, Oliver Faude

    Published 2025-01-01
    “…While MRI provides high accuracy, it is costly and time-consuming. Three-dimensional ultrasonography (3DUS) offers a more accessible alternative but requires rigorous validation due to setup dependent accuracy. …”
    Get full text
    Article
  9. 45669

    Phase I study of pembrolizumab in combination with ibrutinib for the treatment of unresectable or metastatic melanoma by Yuan Yao, Yiyi Yan, Vera J. Suman, Allan B. Dietz, Courtney L. Erskine, Anastasios Dimou, Svetomir N. Markovic, Svetomir N. Markovic, Robert R. McWilliams, Heather N. Montane, Matthew S. Block, Matthew S. Block

    Published 2025-02-01
    “…Pembrolizumab (200 mg/kg every 3 weeks) was combined with ibrutinib, administered orally at the dose assigned at the time of registration (140 mg daily, 280 mg daily, and 420 mg daily). …”
    Get full text
    Article
  10. 45670

    Small RNA CjNC110 regulates the activated methyl cycle to enable optimal chicken colonization by Campylobacter jejuni by Brandon Ruddell, Alan Hassall, Orhan Sahin, Paul J. Plummer, Qijing Zhang, Amanda J. Kreuder

    Published 2025-01-01
    “…Critically, this work for the first time reveals regulation of L-methionine (L-met) production within the activated methyl cycle (AMC) by small RNA (sRNA) CjNC110 as a key factor driving C. jejuni optimal chicken colonization. …”
    Get full text
    Article
  11. 45671

    KiKli Fit: Insights into the Development and Practice of a Physical Activity Program in Pediatric Cancer by Lisa Hillebrech, Lars Rehbein, Ann Christin Schneider, Sara Müller, Christina Schindera, Katharina Eva, Valentin Benzing

    Published 2025-01-01
    “…Building on this, a PA program was designed and implemented over 1.5-years. During this time, various formal and informal assessments were conducted to ensure quality assurance. …”
    Get full text
    Article
  12. 45672

    Immune responses in children with secondary infection of mycoplasma pneumoniae after COVID-19: focus on eosinophils and IgE by Pingping Wang, Jin Yao, Yaqiong Li, Zhanjun Zhang, Ruiling Zhang, Shouting Lu, Meixia Sun, Xiaorong Huang

    Published 2025-01-01
    “…This study provides an important basis for understanding the immune response of children after SARS-CoV-2 infection and its related clinical management, suggesting that clinicians should closely monitor the eosinophil count and IgE level of children after SARS-CoV-2 infection, especially for children at risk of secondary infection, so as to take timely intervention measures to prevent secondary infection with Mycoplasma pneumoniae and improve the prognosis of children.…”
    Get full text
    Article
  13. 45673

    Experimental use of mycobacterial antigens in tuberculin skin test on water buffalo by Alessandra Martucciello, Federica Signorelli, Piera Mazzone, Francesco Grandoni, Giovanna Cappelli, Lucia Boccia, Giuseppe Parente, Monica Cagiola, Maria Beatrice Boniotti, Esterina De Carlo, Francesco Napolitano, Giorgio Galiero

    Published 2023-11-01
    “…Negative subjects also exhibited a skin response to PPDB at 24 and 48 h, but it became completely negative at 72 h, the prescribed reading time. In the positive buffaloes, the kinetics of skin responses showed that the strongest response was to PPDB at 24h, with some subjects becoming doubtful at 72 and 96 h. …”
    Get full text
    Article
  14. 45674

    4-Octyl itaconate inhibits synovitis in the mouse model of post-traumatic osteoarthritis and alleviates pain by Yu-Zhen Tang, Wan Chen, Bao-Yun Xu, Gang He, Xiu-Cheng Fan, Kang-Lai Tang

    Published 2025-01-01
    “…After 12 weeks of surgery, the efficacy of 4-OI treatment on PTOA in mice was evaluated using MRI, micro-CT, histological analysis, and quantitative real-time polymerase chain reaction. Finally, we utilized network pharmacology analysis to predict the mechanism of 4-OI in treating PTOA synovitis and conducted preliminary validation. …”
    Get full text
    Article
  15. 45675

    Long-Term Therapeutic Effects of <sup>225</sup>Ac-DOTA-E[c(RGDfK)]<sub>2</sub> Induced by Radiosensitization via G2/M Arrest in Pancreatic Ductal Adenocarcinoma by Mitsuyoshi Yoshimoto, Kohshin Washiyama, Kazunobu Ohnuki, Ayano Doi, Miki Inokuchi, Motohiro Kojima, Brian W. Miller, Yukie Yoshii, Anri Inaki, Hirofumi Fujii

    Published 2024-12-01
    “…Meanwhile, the γH2AX expression induced by 5 or 10 kBq/mL of <sup>225</sup>Ac-DOTA-RGD<sub>2</sub> alone decreased over time. <b>Conclusions</b>: These findings highlight the potential of using <sup>225</sup>Ac-DOTA-RGD<sub>2</sub> in the treatment of intractable pancreatic cancers, as its ability to induce G2/M cell cycle arrest enhances radiosensitization, resulting in notable growth inhibition.…”
    Get full text
    Article
  16. 45676

    F. NIETZSCHE: VALIOS SIEKTI GALIOS PRINCIPAS by Arūnas Mickevičius

    Published 2004-01-01
    “…With respect to the genesis of power or its generation, the will to power determines the relation between forces, but in its own turn is determined by the activity of these forces. It is at the same time both determined and determiner. Nietzschean „slave“ and „master“ moralities are based upon active and reactive forces. …”
    Get full text
    Article
  17. 45677

    Validity, Accuracy, and Safety Assessment of an Aerobic Interval Training Using an App-Based Prehabilitation Program (PROTEGO MAXIMA Trial) Before Major Surgery: Prospective, Inter... by Sara Fatima Faqar Uz Zaman, Svenja Sliwinski, Lisa Mohr-Wetzel, Julia Dreilich, Natalie Filmann, Charlotte Detemble, Dora Zmuc, Felix Chun, Wojciech Derwich, Waldemar Schreiner, Wolf Bechstein, Johannes Fleckenstein, Andreas A Schnitzbauer

    Published 2025-02-01
    “…Regression analysis revealed a significant impact of the BMI (odds ratio 0.90, 95% CI 0.82-0.98, P=.02) and Timed Up and Go Test score (odds ratio 0.12, 95% CI 0.03-0.55, P=.006) on the accuracy of heart rate measurement; 29 (39%) patients experienced adverse events: pain (5/12, 42%), ECG electrode–related skin irritations (2/42, 17%), dizziness (2/42, 17%), shortness of breath (2/42, 17%), and fatigue (1/42, 8%). …”
    Get full text
    Article
  18. 45678

    Study of the relationships of polymorphisms of the folate cycle genes with the levels of homocysteine and folic acid as risk factors of cardiovascular disorders in the post-covid p... by A.A. Shuprovych, O.V. Zinych, N.M. Kushnareva, K.P. Komisarenko

    Published 2024-10-01
    “…Polymorphisms of the genes: methylenetetrahydrofolate reductase (677C>T and 1298A>C), methionine synthase-reductase (66A>G) and methionine synthase (2756A>G) were determined by real time polymerase chain reaction. For each of the named polymorphisms, the examined patients were divided into 3 groups according to the nucleotide alleles in the corresponding position: 1) homozygous dominant, 2) heterozygous and 3) homozygous recessive. …”
    Get full text
    Article
  19. 45679

    Black Boarding Academies as a Prudential Reparation by Roy Brooks

    Published 2023-05-01
    “…While there has been a transformation of political power, giving Black South Africans a strong voice in the government, economic power remains in the hands of White South Africans and racial discrimination in housing and education continues. Although at one time I was among scholars who had hoped Black Reparations could deliver a much-needed Third Reconstruction, I would be remiss as a passionate supporter of Black Reparations for many decades to ignore the cold facts—reparations have never successfully reconstructed a society. …”
    Get full text
    Article
  20. 45680

    Restructuring of small-scale constructed wetland systems and treatability of individual household wastewater through natural process by S. Mokatip, K. Chunkao, W. Wararam, S. Bualert, O. Phewnil, T. Pattamapitoon, N. Semvimol, P. Maskulrath, P. Rollap, S. Thaipakdee

    Published 2024-07-01
    “…The recommended hydraulic retention time is between 29 and 60 hours under anaerobic conditions and 3 days under aerobic conditions. …”
    Get full text
    Article