ZC3H15 suppression ameliorates bone cancer pain through inhibiting neuronal oxidative stress and microglial inflammation by Li-Quan Huang, Ting-Xuan Yan, Bao-Sheng Wang, Hao Li, Nai-Bao Zhou

“…Results: In this study, we established a bone cancer pain (BCP) murine mouse model that impairs patients’ quality of life. Initially, we observed a significant increase in the expression of ZC3H15 in dorsal horn spinal cord tissues of BCP mice, along with severe oxidative stress and inflammation. …”
Get full text

Hurricane Effects on a Shallow Lake Ecosystem and Its Response to a Controlled Manipulation of Water Level by Karl E. Havens, Kang-Ren Jin, Andrew J. Rodusky, Bruce Sharfstein, Mark A. Brady, Therese L. East, Nenad Iricanin, R. Thomas James, Matthew C. Harwell, Alan D. Steinman

“…However, submerged plant biomass did not exceed levels observed during summer 1999 (when water depths were greater) until August. …”
Get full text

Single-cell atlas reveals multi-faced responses of losartan on tubular mitochondria in diabetic kidney disease by Zhen Zhu, Guangxin Luan, Song Wu, Yiyi Song, Shuang Shen, Kaiyue Wu, Shengnan Qian, Weiping Jia, Jun Yin, Tao Ren, Jianping Ye, Li Wei

“…Preliminary validation through in vitro and in vivo experiments, including observation of changes in mitochondrial morphology and dynamics using probes such as Mitotracker Red, and evaluation of the effect of losartan on key events of mitochondrial homeostasis perturbation using electron microscopy, laser confocal microscopy, immunofluorescence, and Western blotting. …”
Get full text

Profile of 17ß-estradiol, vitellogenin, and egg diameter during gonad maturation process of striped catfish Pangasianodon hypophthalmus by Wahyu Pamungkas, Dedi Jusadi, Muhammad Zairin Junior, Mia Setiawati, Eddy Supriyono, Imron Imron

“…Gonad maturity development of striped catfish was observed based on egg diameter. Result showed that E2 concentrations were the highest (843.65 pg/mL) on female with maturity stage III, the lowest on the male (26.34 pg/mL), and immature female fish (29.37 pg/mL). …”
Get full text

Sykepleieres erfaringer med deltakelse i beslutningsprosesser under previsitt på intensivavdeling by Karin Elisabeth Olsen, Linn Veronika Breivik, Ådel Bergland, Marie Hamilton Larsen

“…Conclusion: Nurses perceived themselves as having valuable contributions during pre-rounds, but their observations and assessments were seldom solicited by physicians before decisions were made. …”
Get full text

SERT-Deficient Mice Fed Western Diet Reveal Altered Metabolic and Pro-Inflammatory Responses of the Liver: A Link to Abnormal Behaviors by Raymond Cespuglio, Anna Gorlova, Konstantin Zabegalov, Kirill Chaprov, Evgeniy Svirin, Kseniia Sitdikova, Alisa Burova, Boris Shulgin, Ksenia Lebedeva, Alexei V. Deikin, Sergey Morozov, Tatyana Strekalova

“…The significant correlations observed between behavioral measures and pro-inflammatory and metabolic alterations in WD-fed mice suggest the importance of liver-brain interactions and their role in the aberrant behaviors exhibited by Sert-/- mutants. …”
Get full text

Soybean oil, a linoleic acid source, in lamb diets: metabolic, feeding behavior, and ruminal parameters by V. G. O. Lima, L. O. da Silva, J. E. de Freitas Jr., H. D. R. Alba, V. M. Leite, W. P. Silva, D. D. S. Pina, L. C. Leite, C. S. Rodrigues, S. A. Santos, G. G. P. de Carvalho

“…There was a linear reduction in nitrogen intake (<span class="inline-formula"><i>P</i></span> <span class="inline-formula">=</span> 0.007), while no influence (<span class="inline-formula"><i>P</i></span> <span class="inline-formula">&gt;</span> 0.05) of SO inclusion was observed on ruminal fermentation parameters, except for a linear decrease in the concentration of rumen ammonia nitrogen (<span class="inline-formula"><i>P</i></span> <span class="inline-formula">=</span> 0.023). …”
Get full text

Human Capital, Economic Growth and Environmental Quality with Special Emphasis on Public Education Expenditures: An Application of DSGE Models by Yahya Mohaghegh, hashem zare, Mehrzad Ebrahimi

“…Methodology To achieve the goal of the research, a dynamic stochastic general equilibrium (DSGE) model and Bayesian approach have been used. In this regard, observable variables, gross domestic product, private consumption, investment, government expenditure and the gross growth rate of money have been used in the period of 2004 to 2021. …”
Get full text

Modified minimally invasive chevron osteotomy versus traditional incision chevron osteotomy by Run Tang, Jie Yang, Xiao Jun Liang, Yi Li, JunHu Wang, MiaoLuo Jin, Yang Du, Tong Lu, YiXiang Hao

“…In the TIC group comprising 22 patients (32 feet), including 1 male and 21 female patients, aged 40.95 ± 11.60 years, mild and moderate hallux valgus deformities were observed in 10 (18 feet) and 12 cases (14 feet), respectively. …”
Get full text

The Effect of Feeding Different Levels of Mineral Biochar on Performance, Blood Parameters, Production and Milk Composition of Holstein Dairy Cows by Ali Khatibi Bardsiri, Reza Valizadeh, Seyed Hadi Ebrahimi, Pirouz Shakeri, Abbas Ali Naserian

“…The evaluation of the amounts and ratios of glucose, protein, and blood albumin showed that the highest levels of glucose, protein, and albumin in blood plasma were observed in the treatment fed with a basic diet supplemented with 0.5% biochar. …”
Get full text

Correlation of newer inflammatory markers in patients with type 2 diabetes mellitus: A cross-sectional study by Swetha Akkina, Srikanth Akula, Rajeev Gandham, Preethi Batakala, Bhagyalakshmi Atla, Divija Reddy Bonthu, Sunkara Uha Priya

“…Results: In this study, significant increase in blood pressure (systolic [120.4±8.1 mmHg], diastolic [80.2±4.8 mmHg]), fasting blood sugar (FBS) (162.5±53.7 mg/dL), post-prandial blood sugar (238.3±78.8 mg/dL), HbA1c (8.5±2.2%), urea (28.6±8.6 mg/dL), creatinine (1.1±0.2 mg/dL), total cholesterol (186.8±46.1 mg/dL), triglycerides (168.9±61.2 mg/dL), LDLC (115.0±36.3 mg/dL), VLDL (33.8±12.4 mg/dL), and neutrophil count (66.6±11.4%) was observed in T2DM cases. Inflammatory markers such as NLR (4.2±1.1), PLR (0.17±0.01), SII (12.6±3.6), SIRI (25.7±5.2), MHR (0.15±0.08), NHR (1.9±0.72), and PHR (0.07±0.02) were significantly increased in T2DM cases than non-diabetic subjects. …”
Get full text

Myocarditis and neutrophil-mediated vascular leakage but not cytokine storm associated with fatal murine leptospirosisResearch in context by Stylianos Papadopoulos, David Hardy, Frédérique Vernel-Pauillac, Magali Tichit, Ivo G. Boneca, Catherine Werts

“…Interpretation: Despite clinical similarities between bacterial sepsis and leptospirosis, striking differences were observed, in particular a lack of cytokine storm in acute leptospirosis. …”
Get full text

Spare Parts Inventory Optimization for Military Vehicles Using a Mixed Probability Distribution by Mojtaba Salehi, Mojtaba Omidvar, Shohreh Shariati

“…As the model is subjected to more iterations, differences in results are observed, indicating the potential for variability with increasing iterations. …”
Get full text

Kidney Function and Incident Stroke and Dementia Using an Updated Estimated Glomerular Filtration Rate Equation Without Race: The Multi-Ethnic Study of Atherosclerosis by Samuel R. Moen, Jeffrey R. Misialek, Timothy M. Hughes, Craig W. Johnson, Mark J. Sarnak, Sarah N. Forrester, W.T. Longstreth, Jr., Mercedes R. Carnethon, James S. Pankow, Sanaz Sedaghat

“…Study Design: Prospective observational study. Setting &amp; Participants: Baseline values were collected from 6,814 participants in the Multi-Ethnic Study of Atherosclerosis (MESA) cohort between 2000 and 2002. …”
Get full text

Functional assessment of the glycoproteins of a novel Hendra virus variant reveals contrasting fusogenic capacities of the receptor-binding and fusion glycoproteins by Andrew Z. Ma, Yao Yu Yeo, Jean F. Lee, Colin M. Kim, Shahrzad Ezzatpour, Carolina Menchaca, Viraj Upadhye, Edward J. Annand, John-Sebastian Eden, Raina K. Plowright, Alison J. Peel, David W. Buchholz, Hector C. Aguilar

“…These fusion phenotypes were more closely associated with those observed in the related NiV. Further investigation using HeV-g1 and HeV-g2 glycoprotein chimeras revealed that multiple domains may play roles in modulating these fusion phenotypes. …”
Get full text

Risk of hepatocellular carcinoma in Asian patients with primary biliary cholangitis: A nationwide and hospital cohort study by Jihye Lim, Ye-Jee Kim, Sehee Kim, Jonggi Choi

“…Impact and implications:: Notable heterogeneity has been observed among different studies in terms of the incidence of hepatocellular carcinoma (HCC) in patients with primary biliary cholangitis (PBC). …”
Get full text

Characterization of probiotic Bacillus sp. NP5 metabolites and their effect on female catfish broodstock re-maturation by Valensia Enzeline, Widanarni Widanarni, Agus Oman Sudrajat, Alimudin Alimudin

“…Subsequently, feed supplementation with the probiotic was implemented at concentrations of 106 CFU/g (P6), 108 CFU/g (P8), and control (C). Parameters observed included the metabolite content of Bacillus sp. …”
Get full text

The role of teacher-related factors in enhancing quality service provision in pre-primary schools of Gambella regional state, Ethiopia by Challa Ayale Legede, Tadesse Regassa Mamo, Desalegn Beyene Debelo, Abunu Arega Yismaw

“…Data were collected through surveys, observations, interviews and focus group discussions involving education experts, school principals, teachers and parent–teacher association leaders. …”
Get full text

Relationship between changes in the triglyceride glucose-body mass index and frail development trajectory and incidence in middle-aged and elderly individuals: a national cohort st... by Kai Guo, Qi Wang, Lin Zhang, Rui Qiao, Yujia Huo, Lipeng Jing, Xiaowan Wang, Zixuan Song, Siyu Li, Jinming Zhang, Yanfang Yang, Jinli Mahe, Zhengran Liu

“…A U-shaped association was observed between TyG-BMI levels and both rapid FI trajectory and higher frail risk, with BMI being the primary factor. …”
Get full text

The potential of bacteriophage for controlling Vibrio parahaemolyticus as in-vitro by Bagus Ansani Takwin, Dinamella Wahjuningrum, Widanarni Widanarni, Hasan Nasrullah

“…All phage density treatments effectively reduced V. parahaemolyticus density compared to the negative control, with the most favorable results observed in the FB9 treatment at a density of 109 PFU/mL.   …”
Get full text