Potential pharmacological effect of Quercetin Phytosome™ in the management of hyperuricemia: results from real-life clinical studies by Francesco Di Pierro, Francesco Di Pierro, Francesco Di Pierro, Fazle Rabbani, Meherullah Tareen, Roohi Nigar, Amjad Khan, Nicola Zerbinati, Maria L. Tanda, Massimiliano Cazzaniga, Alexander Bertuccioli, Alexander Bertuccioli, Paolo Falasca, Gabriele Damiani, Nicola Villanova

“…Primary endpoints were reductions in serum uric acid levels, while secondary outcomes included effects on lipid profile, glycemia, liver enzymes, and treatment tolerability.ResultsIn Cohort 1, QP significantly reduced uric acid levels by 15.2% in males and 13.8% in females, with no significant changes observed in the probiotic group. Cohort 2 showed a significant 13.1% reduction in uric acid (p < 0.01) and a concurrent 10.2% reduction in triglycerides (p < 0.05). …”
Get full text

A socio-ecological model of the management of leprosy reactions in Indonesia and India using the experiences of affected individuals, family members and healthcare providers by Annisa Ika Putri, Ruth M. H. Peters, Kevin De Sabbata, Brittney S. Mengistu, Regitta I. Agusni, Medhi Denisa Alinda, Joydeepa Darlong, M. Yulianto Listiawan, Cita R. S. Prakoeswa, Stephen L. Walker, Marjolein B. M. Zweekhorst

“…Furthermore, variations in care-seeking behaviour and self-care practices were observed in both sites, underscoring the need for culturally sensitive and comprehensive approaches to the management of LR. …”
Get full text

Hubungan Faktor Risiko Terhadap Kejadian Sindroma Koroner Akut pada Pasien Dewasa Muda di RSUP Dr. M. Djamil Padang by Anggita Tiara Pramadiaz, Muhammad Fadil, Henny Mulyani

“…</em><em>The objective of tthis study was </em><em>to determine the relationship of risk factors</em><em> of</em><em> ACS in young adults.This </em><em>wa</em><em>s an analytic observational cross-sectional design conducted at </em><em>Dr.…”
Get full text

Harnessing Big Heterogeneous Data to Evaluate the Potential Impact of HIV Responses Among Key Populations in Sub-Saharan Africa: Protocol for the Boloka Data Repository Initiative by Refilwe Nancy Phaswana Mafuya, Edith Phalane, Amrita Rao, Kalai Willis, Katherine Rucinski, K Alida Voet, Amal Abdulrahman, Claris Siyamayambo, Betty Sebati, Mohlago Seloka, Musa Jaiteh, Lerato Lucia Olifant, Katharine Journeay, Haley Sisel, Xiaoming Li, Bankole Olatosi, Neset Hikmet, Prashant Duhoon, Francois Wolmarans, Yegnanew A Shiferaw, Lifutso Motsieloa, Mashudu Rampilo, Stefan Baral

“…There exists an opportunity to harness a variety of data, such as empirical, contextual, observational, and programmatic data, for evaluating the potential impact of HIV responses among KPs in South Africa. …”
Get full text

Ovulation time and ovulated eggs count of sneakehead Channa striata induced by prostaglandin 2α with different doses by Frits Jamlaay, Maheno Sri Widodo, Abd. Rahem Faqih

“…Each treatment consisted of three fishes as replication. Ovulation time was observed until 72 hours post injection. The results showed that PGF2α injected broodstoks ovulated faster (9.17–12.24 hours post injection) than control P1 (22.67 hours), while among PGF2α injected fishes were the same. …”
Get full text

Network and systems biology approaches help investigate gene regulatory interactions between Salmonella disease and host in chickens: Model‐based in silico evidence combined with g... by Reza Tohidi, Hoda Javaheri Bargourooshi, Arash Javanmard

“…This molecular study was developed in the second phase of research to validate the in silico observations. Next, we use five promising biomarkers for relative real‐time polymerase chain reaction (PCR) quantification: TLR4, IL8, NRAMP1, IFNγ and IgY genes in two case and control assays. …”
Get full text

Biological embodiment of educational attainment and future risk of breast cancer: findings from a French prospective cohort by Cyrille Delpierre, Raphaële Castagné, Eloïse Berger, Gianluca Severi, Marie-Christine Boutron-Ruault, Laura Baglietto, Laure Dossus, Amandine Gelot, Richard Dudouet

“…Many studies support the hypothesis that education has a distinctive effect on physiological processes associated with health, independently of known risk factors.Objectives In this study, we aimed to determine whether the biological embodiment of education could be part of the observed social inequalities in BC risk. We focused on biomarkers from several physiological systems examined individually, and jointly through a biological health score (BHS).Design Prospective cohort study.Setting This study, based on a subsample of the French E3N cohort, included women with biological data from four nested case–control studies.Participants The study included 3048 postmenopausal women (17% BC).Main outcome measures We first evaluated the association between educational attainment and each biomarker, separately (N=11) and by combining them into a BHS, indicative of an augmented biological health hazard when elevated. …”
Get full text

Comparative microbial metagenomic analysis of drinking water plants and wastewater treatment plants in Istanbul by Mehmet Demirci, Cankut Çubuk, Ferhat Dasdemir, Abdulkerim Suat Saribas, Esra Billur Balcıoglu, Dogukan Ozbey, Dogu Yorulmaz, Tugba Olmez Hanci, Safak Basa, Bekir Sami Kocazeybek, Bekir Sami Kocazeybek

“…The aim of this study was to detect the microbiome profiles of waters from both DWTPs and WWTPs under the Istanbul Water and Sewerage Administration (ISKI), identify the antimicrobial resistance profiles in all these facilities, and observe the differences in the microbiome between the inlet and outlet of different WWTPs.MethodsA total of 52 samples were examined, comprising 18 samples from DWTPs and 34 samples from WWTPs. …”
Get full text

Effect of oodev and turmeric powder dietary supplementations on the reproductive performance of sunset platy fish Xiphophorus maculatus by Harton Arfah, Odang Carman, Muhamad Fathurrizki Darmawan, Fajar Maulana, Lina Mulyani

“…There were three replications for each treatment. The observed parameters included the percentage of pregnant broodstocks, the percentage of labored broodstocks, the frequency of labored broodstocks, larvae production, and the survival rate of the larvae. …”
Get full text

Formation of forest mensuration indicators of Pseudotsuga menziesii (Mirb.) Franco in artificial plantations of the western region of Ukraine by Iurii Debryniuk, Stepan Myklush, Yuriy Myklush

“…Even in a plantation aged 105 years, the tree species maintains a high growth intensity (site index class Ic). The observed variability in diameter change of Pseudotsuga menziesii across plantations, where the species’ share ranges from 10 to100%, significantly exceeds the variability in height growth. …”
Get full text

Modified neuroimmune processes and emotional behaviour in weaned and late adolescent male and female mice born via caesarean section by Mathieu Di Miceli, Moïra Rossitto, Maud Martinat, Flore Marchaland, Sarah Kharbouche, Marion Graland, Farah Younes, Alexandra Séré, Agnès Aubert, Lydia Rabbaa Khabbaz, Charlotte Madore, Jean-Christophe Delpech, Rebeca Martín, Sophie Layé

“…In this study, we used a validated model of mice born by C-section (CSD), which mimics clinical observations of dysregulated gut microbiota. Animals were either born naturally or by CSD, before being adopted by dams who underwent delivery within the 12 preceding hours. …”
Get full text

Gambaran Antropometri pada Penyakit Jantung Bawaan di RSUP Dr. M. Djamil Padang Tahun 2010 -2013 by Muhammad Nadirsyah, Didik Haryanto, M. Setia Budi Zein

“…Anthropometry is a method to determine the nutrition status by using the anthropometric measurement; Weight-for-Age, Length for Age, and Weight for Length.T</em><em>he  objective of this</em><em> study </em><em>was</em><em> to observe the anthropometric description in cyanotic and non-cyanotic congenital heart disease at Dr. …”
Get full text

Induced maturation of eel Anguilla bicolor using different hormone combination by Agus Oman Sudrajat, Antharest Sugati, , Alimuddin

“…Hormonal induction was conducted by intramuscular injections, as much as five times at intervals of seven days. Furthermore observations on gonadal development were performed after injection for 21 days. …”
Get full text

Comparison of fluorescence in situ hybridization (FISH) and urine cytology in diagnosing urothelial carcinoma: a single-center retrospective cohort study by WANG Zhiting, ZHU Xiaoli

“…The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist and Standards for Reporting of Diagnostic Accuracy (STARD) were followed for this study. …”
Get full text

Pengaruh Lama Pemberian Diet Tinggi Kolesterol terhadap Kadar LDL dan TGF-Β Serum Tikus Putih (Rattus novergicus) strain Wistar by Biomechy Oktomalioputri, Eryati Darwin, Eva Decroli

“…The objective of this study was to observe the effect of duration of giving  high-cholesterol diet on Low Density Lipoprotein and Transforming Growth Factor β levels white rats (Rattus novergicus) Wistar strain. …”
Get full text

Variations in vitamin D status among Chinese children aged 1–6 years during the COVID-19 pandemic by Yongfeng Qiao, Xiaoqin Wang, Yanfen Ma, Jian Hu

“…Total 25(OH)D concentrations were compared between the two observation periods. Vitamin D status was determined by 25(OH)D concentrations: deficient (&lt;20 ng/ml), insufficient (20–29 ng/ml), and sufficient (30–100 ng/ml).ResultsThe study involved 6,780 children, with 52.8% being 1-year-olds, 23.1% being 2-year-olds, and 24.1% being 3 to 6-year-olds. …”
Get full text

Analyzing the serum biochemical factors that influence early neurological deterioration in ischemic Stroke patients and developing a nomogram prediction model by Xiaoni Zhan, Yunyun Xu, Rongrong Ma

“…Methods: General clinical data from 220 IS patients treated between December 2022 and November 2023 were collected for observation. The study's inclusion and exclusion criteria select patients aged 18+ with a first-time diagnosis of IS who undergo lab tests within 24 hours of admission while excluding those with multiple organ dysfunction, sensory impairments, coagulation disorders, or other serious medical conditions. …”
Get full text

Reproductive performance of catfish Clarias sp. with probiotics Bacillus sp. NP5 addition through feed by Safira Qisthina Ayuningtyas, Muhammad Zairin Jr., Widanarni

“…Catfish broodstocks with an average size of 955 ± 261.27 g were kept in a net sized 1 m×1 m×1 m with seven broodstocks per net. Parameters observed included the Gonadosomatic Index (GSI), fecundity, number of matured eggs, frequency distribution of egg diameter, fertilization rate, and hatching rate. …”
Get full text

Hubungan Stresor Psikososial pada Kehamilan dengan Partus Prematurus by Yuli Nenti Herlina, Desmiwarti ., Edison .

“…T</em><em>he objective of t</em><em>his study </em><em>wa</em><em>s </em><em>to</em><em> determi</em><em>ne</em><em> the relationship between psychological stressor and preterm labor.This </em><em>was</em><em> an observational analytic study with case control design. …”
Get full text

The used of chopped banana Musa paradisiaca stem for stimulating immune responses and streptococcosis resistance of Nile tilapia Oreochromis niloticus by Lilis Nurjanah, Sri Nuryati, Alimuddin Alimuddin, Kukuh Nirmala

“…The immersion treatment with the chopped banana stem was done for 14 days, then the challenge test with S. agalactiae was on the 15th day for 14 days observation. The result showed that chopped banana stem contained active compounds of alkaloids, namely: 17.63% flavonoids, 0.02% tannin and 0.24% saponins. …”
Get full text