Time trends in mechanical thrombectomy (2017–2021): do real-world data reflect advances in evidence? by Christoph Riegler, Christoph Riegler, Viktoria Rücker, Regina von Rennenberg, Regina von Rennenberg, Kerstin Bollweg, Kerstin Bollweg, Bastian Cheng, Anna C. Alegiani, Fabian Flottmann, Marlena Schnieder, Marielle Ernst, Waltraud Pfeilschifter, Waltraud Pfeilschifter, Waltraud Pfeilschifter, Christoffer Kraemer, Ruben Mühl-Benninghaus, Steffen Tiedt, Steffen Tiedt, Lars Kellert, Hanna Zimmermann, Felix J. Bode, Felix J. Bode, Gabor C. Petzold, Gabor C. Petzold, Franziska Dorn, Jörg Berrouschot, Albrecht Bormann, Kathleen Bernkopf, Silke Wunderlich, Tobias Boeckh-Behrens, Martina Petersen, Lars Udo Krause, Stephan Lowens, Heinrich J. Audebert, Heinrich J. Audebert, Eberhard Siebert, Peter U. Heuschmann, Peter U. Heuschmann, Peter U. Heuschmann, Christian H. Nolte, Christian H. Nolte, Christian H. Nolte, Christian H. Nolte

“…Despite these patients presenting with less severe stroke symptoms, improvements in functional outcomes were not observed, and mortality rates increased. These trends may reflect willingness to treat patients with more severe underlying health conditions.…”
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Shedding light on the existence of Furan fatty acids in latex lipids across a wide diversity of Hevea brasiliensis genotypes by Chaisiri Kitpaosong, Siriluck Liengprayoon, Erwann Durand, Tucksin Lerksamran, Aurélie Daval, Eric Gohet, Lim Khan Tiva, Phean Chetha, Kong Mengchheang, Phen Phearun, Ung Rattana, Kim Chandy, Pol Sokea, Un Kim Eng, Kittipong Rattanaporn, Bruno Barea, Laurent Vaysse

“…A positive correlation with total fatty acid content was observed when its content exceeded 0.10%, suggesting an additive rather than a substitutive role with the other fatty acids present. …”
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Sex differences in the associations of water, coffee and tea consumption with cardiovascular diseases: a prospective cohort study by Dandan Ke, Dandan Ke, Yueqing Wang, Yabing Hou, Weihao Shao, Jiawen Ke, Xiaoxuan Zhang, Hongxi Yang, Zhong He, Zuolin Lu

“…Furthermore, significant sex differences were observed in the associations between coffee or tea consumption and CHD incidence.…”
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Potential Mechanisms and Effects of Dai Bai Jie Ethanol Extract in Preventing Acute Alcoholic Liver Injury by Niantong Xia, Hongwei Xue, Yihang Li, Jia Liu, Yang Lou, Shuyang Li, Yutian Wang, Juan Lu, Xi Chen

“…The total saponin level in the DBJ extracts was measured using vanillin–chloroform acid colorimetry. To observe the preventive and protective effects of DBJ on AML-12 cells in an ethanol environment, the effective components of DBJ were identified. …”
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Yishenyangsui granule for degenerative cervical myelopathy: a randomized, double-blind, placebo-controlled trial with long-term follow-up by He Yin, Xin Chen, Zhiwei Liu, Zhiwei Liu, Bo Xu, Zhefeng Jin, Yan Liu, Baoyu Qi, Bin Tang, Ping Wang, Fanping Xu, Xu Wei, Jie Yu, Liguo Zhu, Liguo Zhu

“…However, there was a significant difference detected in re-treatment data between groups with a lower rate observed among those receiving Yishenyangsui granule compared to those receiving placebo [25 (43.10%) vs. 40 (68.97%); P = 0.033], indicating its effectiveness for treating mild-to-moderate Degenerative Cervical Myelopathy.ConclusionYishenyangsui granule was effective in treating mild to moderate Degenerative Cervical Myelopathy. …”
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Compaction of Hyaloclastite from the Active Geothermal System at Krafla Volcano, Iceland by Guðjón H. Eggertsson, Jackie E. Kendrick, Joshua Weaver, Paul A. Wallace, James E. P. Utley, John D. Bedford, Michael J. Allen, Sigurður H. Markússon, Richard H. Worden, Daniel R. Faulkner, Yan Lavallée

“…Beyond this mean effective stress, denoted as P∗, we observed accelerated porosity and permeability reduction with increasing confinement, as the rock underwent permanent inelastic compaction. …”
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Demographic variation and socioeconomic inequalities in all forms of malnutrition among children aged 6 months to 9 years: findings from the Vietnamese General Nutrition Survey 202... by J Bernadette Moore, Xiaodong Lin, Louise Dye, Van Khanh Tran, Yun Yun Gong, Xiaomian Tan, Pui Yee Tan, Somphos Vicheth Som, Son Duy Nguyen, Do Tranh Tran, Nga Thuy Tran, Samantha Caton, Hannah Ensaff, Geoffry Smith

“…Low serum zinc, anaemia and iron deficiency were the common MNDs observed, affecting 53.1%, 15.2% and 13.9% of the study participants. …”
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Selective expression and significance of ACKR2 in lung aerocytes by Alberto Mantovani, Gianluigi Condorelli, Raffaella Bonecchi, Massimo Locati, Marina Sironi, Roberta Carriero, Francesca Albano, Valeria Mollica Poeta, Lucia Zotti, Alessandra Castagna, Arianna Felicetta, Alessandro Mesaglio, Elisa Zaghen, Arianna Capucetti, Rachele Di Donato, Mattia Laffranchi, Matteo Massara, Silvano Sozzani

“…However, uniquely in the lungs, ACKR2 expression is observed in blood endothelial cells (BECs), specifically in capillaries known as aerocytes specialized for regulating leukocyte trafficking. …”
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The IL-1B Gene Polymorphisms rs16944 and rs1143627 Contribute to an Increased Risk of Coronary Artery Lesions in Southern Chinese Children with Kawasaki Disease by Lan Yan Fu, Xiantao Qiu, Qiu Lian Deng, Ping Huang, Lei Pi, Yufen Xu, Di Che, Huazhong Zhou, Zhaoliang Lu, Yaqian Tan, Zhiyong Jiang, Li Zhang, Techang Liu, Xiaoqiong Gu

“…According to the results, no significant association was observed between the IL-1B (rs16944 and rs1143627) polymorphisms and KD risk in the patients compared with the healthy controls in our southern Chinese population. …”
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Breaking the biofilm barrier: Juglone derivatives as dual-action inhibitors and anti-quorum sensing agents by Muhammad Abdullah Bhatti, Atif Ali Khan Khalil, Sayed Muhammad Ata Ullah Shah Bukhari, Faisal Hanif, Mi-Jeong Ahn, Sumra Wajid Abbasi, Nazir Ahmed Lone, Wen-Jun Li, Wasim Sajjad

“…The untreated MRSA exhibited quorum sensing signals of N-Butanoyl-l-homoserine lactone (C4-HSL) with retention time 3.6 min and of N-hexanoyl-l-Homoserine lactone (C6-HSL) at 5.8 minutes’ vs the treated with MRSA where no peaks were observed. The docking studies and Molecular dynamics (MD) simulation results revealed that all molecules are actively binding in the target site that correlates well with the in-vitro inhibitory properties of compounds against S. aureus. …”
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The effect of iron deficiency on cardiac resynchronization therapy: results from the RIDE‐CRT Study by Philipp Lacour, Phi Long Dang, Daniel Armando Morris, Abdul Shokor Parwani, Wolfram Doehner, Franziska Schuessler, Felix Hohendanner, Frank R. Heinzel, Andrea Stroux, Carsten Tschoepe, Wilhelm Haverkamp, Leif‐Hendrik Boldt, Burkert Pieske, Florian Blaschke

“…Methods and results The relation of iron deficiency and cardiac resynchronization therapy response (RIDE‐CRT) study is a prospective observational study. We enrolled 77 consecutive CRT recipients (mean age 71.3 ± 10.2 years) with short‐term follow‐up of 3.3 ± 1.9 months and long‐term follow‐up of 13.0 ± 3.2 months. …”
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Revealing the biological features of the axolotl pancreas as a new research model by Hui Ma, Hui Ma, Hui Ma, Guangcong Peng, Yan Hu, Binbin Lu, Binbin Lu, Yiying Zheng, Yingxian Wu, Weimin Feng, Yu Shi, Xiangyu Pan, Li Song, Ina Stützer, Yanmei Liu, Jifeng Fei, Jifeng Fei, Jifeng Fei

“…Pancreatic development was observed using in situ hybridization and immunostaining for key pancreatic markers. …”
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Coronary plaque characteristics quantified by artificial intelligence-enabled plaque analysis: Insights from a multi-ethnic asymptomatic US population by Guadalupe Flores Tomasino, Caroline Park, Kajetan Grodecki, Jolien Geers, Donghee Han, Andrew Lin, Keiichiro Kuronuma, Nipun Manral, Emily Xing, Heidi Gransar, Sebastien Cadet, Alan Rozanski, Piotr J. Slomka, Michelle Williams, Daniel S. Berman, Damini Dey

“…African American patients were associated with lower quantitative plaque volumes (total, non-calcified and calcified) but with higher PCAT compared to White patients; with no significant differences observed among other ethnic minorities.…”
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Expression of USP18 and IL2RA Is Increased in Individuals Receiving Latent Tuberculosis Treatment with Isoniazid by Eleane de Oyarzabal, Lourdes García-García, Claudia Rangel-Escareño, Leticia Ferreyra-Reyes, Lorena Orozco, María Teresa Herrera, Claudia Carranza, Eduardo Sada, Esmeralda Juárez, Alfredo Ponce-de-León, José Sifuentes-Osornio, Robert J. Wilkinson, Martha Torres

“…Expression of chemokine ligand 4 (CCL4), chemokine ligand 10 (CXCL10), chemokine ligand 11 (CXCL11), interferon alpha (IFNA), radical S-adenosyl methionine domain-containing 2 (RSAD2), ubiquitin-specific peptidase 18 (USP18), interferon-induced protein 44 (IFI44), interferon-induced protein 44 like (IFI44L), interferon-induced protein tetratricopeptide repeats 1(IFIT1), and interleukin 2 receptor subunit alpha (IL2RA) mRNA levels were assessed by qPCR before, during, and after INH treatment. Results. We observed significantly lower relative abundances of USP18, IFI44L, IFNA, and IL2RA transcripts in PBMC from IGRA-positive individuals compared to levels in IGRA-negative individuals before INH therapy. …”
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Exploring the genomic and antimicrobial resistance tapestry: comparative insights into Salmonella enterica serotypes Agona, Braenderup, Muenchen, and Panama in Latin American surfa... by Zhao Chen, Enrique J. Delgado Suárez, Raquel R. Bonelli, Celso J. B. Oliveira, Andrea I. Moreno-Switt, Aiko D. Adell, Angélica Reyes-Jara, Christopher J. Grim, Marc W. Allard, Sandra M. Tallent, Eric W. Brown, Rebecca L. Bell, Magaly Toro, Jianghong Meng

“…However, a notable exception was observed with one S. Agona isolate from Brazil closely related to two isolates from Chile, differing by only 18 and 19 single-nucleotide polymorphisms, respectively.IMPORTANCEThis comprehensive study explored the intricate genomic landscapes of S. …”
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The agronomic mechanism of root lodging resistance and yield stability for sweet corn in response to planting density and nitrogen rates at different planting dates by Qinggan Liang, Qinggan Liang, Qinggan Liang, Qinggan Liang, Hailong Chang, Hailong Chang, Hongrong Chen, Hongrong Chen, Qingdan Wu, Qingdan Wu, Yuanxia Qin, Zhuqing Wang, Gang Wang, Xuhui Li, Weiwei Chen, Jiantao Wu, Jiantao Wu, Qinnan Wang, Jianqiang Wang, Jianqiang Wang

“…This further improved the development of plant crown architecture, including stem nodes and ear leaf traits, and further coordinated dry matter dynamics and lignin metabolism between the root and shoot organs. These observations may account for the resistance of the roots to lodging in this treatment. …”
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Impaired hemodynamic forces assessed by routine CMR and its determinants in different duration T2DM patients with normal LV function and myocardial strain by Guozhu Shao, Guozhu Shao, Guozhu Shao, Yukun Cao, Yukun Cao, Yukun Cao, Yue Cui, Yue Cui, Yue Cui, Hongyan Li, Heshui Shi, Heshui Shi, Heshui Shi

“…LV deformation parameters, global circumferential strain (LVGCS), radial strain (LVGRS), longitudinal strain (LVGLS) and HDFs parameters such as longitudinal (apical-basal/A-B), transversal (lateral-septal/L-S) HDF strength (RMS) were measured and compared among the three groups.ResultsCompared with healthy volunteers, no significant differences in LV function and strains were observed (P > 0.05), while HDF Strength (RMS) L-S (%) were significantly higher in T2DM patients (p < 0.001). …”
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A sea ice deformation and rotation rate dataset (2017–2023) from the Environment and Climate Change Canada automated sea ice tracking system (ECCC-ASITS) by M. Plante, J.-F. Lemieux, L. B. Tremblay, A. Bouchat, D. Ringeisen, D. Ringeisen, P. Blain, S. Howell, M. Brady, A. S. Komarov, B. Duval, L. Yakuden, F. Labelle

“…The heterogeneity and localization of these sea ice deformations are important characteristics of the sea ice cover that can be used to evaluate the performance of dynamical sea ice models against observations across multiple spatial and temporal scales. …”
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An outbreak within an outbreak: The impact of Infection Prevention and Control strategies on hospital-acquired infections and the occurrence of multi-drug resistant organisms durin... by B Mashigo, A Parker, U Lalla, B W Allwood, M S Moolla, T Lovelock, C F N Koegelenberg

“…Patients with any HAI had a longer mean stay in ICU (10.1 days v. 6.7 days (p<0.01) and a higher mortality of 48/59 (81%) v. 19/31 (61%) (p=0.05). Conclusion. We observed a very significant rise in HAIs in the COVID-19 ICU during the third wave compared with the first, with almost three times as many patients developing HAIs. …”
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Translingual neural stimulation induced changes in intra- and inter-network functional connectivity in mild-moderate traumatic brain injury patients by Daniel Y. Chu, Jiancheng Hou, Thomas Hosseini, Veena A. Nair, Nagesh Adluru, Yuri Danilov, Kurt A. Kaczmarek, Mary E. Meyerand, Mitchell Tyler, Mitchell Tyler, Vivek Prabhakaran

“…Moreover, significant increases in intra- and inter-network RSFC were observed, particularly within the visual, default mode, dorsal attention, frontoparietal (FPN), and somatosensory (SMN) networks. …”
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