Exploring the Causal Relationship and Molecular Mechanisms Between Fasting Insulin and Androgenetic Alopecia: A Mendelian Randomization Study with Bioinformatics Analysis by Ding X, Bai Z, Wang W, Gu Y, Li Z, Fan Y

“…FI-associated genes were identified through expression quantitative trait loci (eQTL) analysis, with enrichment analysis and a protein-protein interaction (PPI) network used to explore potential pathways and core genes.Results: Forward MR analysis revealed a significant causal relationship between elevated FI levels and AGA (P=0.027, OR=43.944). …”
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Predictors of frequency of CF care in the US Cystic Fibrosis Foundation Patient Registry. by Alexandra C Hinton, Edmund H Sears, Jonathan B Zuckerman, Sara Lopez-Pintado

“…Risk factors for gaps in care should inform changes to CF care recommendations going forward.…”
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Time-varying harmonic impedance estimation based on locally-geographically weighted regression by XU Fangwei, XIE Pei′ang, WANG Chuan, LIU Kai, GUO Kai, FAN Lijuan

“…As a consequence, a brand new time-varying utility harmonic impedance estimation method is put forward based on locally-geographically weighted regression. …”
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A Bidirectional Mendelian Randomization Study Investigating the Causal Relationship Between Ankylosing Spondylitis and Chronic Obstructive Pulmonary Disease by Pan D, Dai X, Li P, Xue L

“…Sensitivity analyses were also performed to evaluate the impact of heterogeneity and pleiotropy on the MR results.Results: The study included two datasets related to AS (ebi-a-GCST005529 and ukb-a-88) and two datasets related to COPD (ebi-a-GCST90018807 and finn-b-J10_COPD). In our forward MR, the analysis of ebi-a-GCST005529 dataset against ebi-a-GCST90018807 dataset showed that AS was associated with an increased risk of COPD (OR = 1.1326, 95% CI = 1.0181– 1.2600, P = 0.0221). …”
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The plant germplasm and herbarium (WIR) collections maintained at VIR as contributors to grape genetic diversity conservation, expansion and utilization by M. M. Agakhanov, L. V. Bagmet, N. G. Tikhonova, M. V. Erastenkova, E. N. Kislin, Yu. V. Ukhatova, E. K. Khlestkina

“…Therefore, grape wild relatives need to be studied thoroughly using modern methods of forward and reverse genetics. Regarding the issues of grape genetic diversity conservation and expansion at the current technological stage, the status and significance of the plant germplasm and herbarium (WIR) collections held by VIR are scrutinized in detail. …”
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Low-budget equipment facilitating skid coefficient extraction for traffic accident analysis by Vinicius Lima, Umit Karabiyik, Felipe Kennedy, Igor Mello, Jorge Farias, Manoel Martins

“…By addressing key limitations of existing methods, this tool represents a significant step forward in the field.…”
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Application and development of CRISPR technology in the secondary metabolic pathway of the active ingredients of phytopharmaceuticals by Haixin Gao, Xinyi Pei, Xianshui Song, Shiying Wang, Zisong Yang, Jianjun Zhu, Qiupeng Lin, Qinlong Zhu, Xiangna Yang

“…At the same time, this article puts forward some insights in order to provide new ideas for the subsequent application of CRISPR in medicinal plants. …”
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Performance Analysis of a Strong Constraint 4DVar and 4DEnVar on Regional Ionosphere Imaging by Nicholas Ssessanga, Wojciech Jacek Miloch, Lasse Boy Novock Clausen, Daria Kotova

“…Both schemes initialize from the same background (IRI‐2016), and electron densities forward propagated (30‐min) by a Gauss Markov filter‐ the densities take on a log‐normal distribution to assert the mandatory ionosphere density positive definiteness. …”
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Reference Value for the Distance Walked in the Six-Minute Walk Test in Obese Brazilian Men in the Preoperative Period of Bariatric Surgery by Cesar Antonio Luchesa, Thiago Thomaz Mafort, Rafael Rodrigues da Silva, Isabela Cristina Paro, Fernanda Micheli de Souza, Agnaldo José Lopes

“…The 6 MWD was correlated with age (r = −0.388, p=0.0005), weight (r = −0.365, p=0.0007), height (r = 0.285, p=0.022), body mass index (BMI) (r = −0.543, p<0.0001), forced vital capacity (FVC) (r = 0.472, p<0.0001), peak expiratory flow (r = 0.253, p=0.031), and maximal inspiratory pressure (r = 0.313, p=0.017). In the stepwise forward regression analysis, BMI, FVC, and age were the only variables that independently predicted the 6 MWD and explained 40% of its variability. …”
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Influenza and Bacterial Pathogen Coinfections in the 20th Century by Xuan-Yi Wang, Paul E. Kilgore, Kyung Ah Lim, Song-Mei Wang, Jeongseok Lee, Wei Deng, Mei-Qi Mo, Batmunkh Nyambat, Jing-Chen Ma, Michael O. Favorov, John D. Clemens

“…These results suggest that bacterial pathogens will play a key role in many countries, as the H1N1(A) influenza pandemic moves forward. Given the role of bacterial coinfections during influenza epidemics and pandemics, the conduct of well-designed field evaluations of public health measures to reduce the burden of these common bacterial pathogens and influenza in at-risk populations is warranted.…”
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OLED-on-silicon (OLEDoS) microdisplays: Technology challenges, design considerations, and adaptation in eXtended Reality (XR) ecosystem – Review by Rifat Kaçar, Ramis Berkay Seri̇n, Esin Uçar, Murat Artuç, Alper Ülkü, Barış Kınacı

“…In conclusion, it provides a forward-looking perspective on the future of OLEDoS microdisplays, outlining emerging trends and opportunities within the rapidly evolving XR ecosystem.…”
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An optimized method for AUV trajectory model in benthonic hydrothermal area based on improved slime mold algorithm by Chunmeng Jiang, Yiming Tang, Jianguo Wang, Wenchao Zhang, Min Zhou, Jiaying Niu, Lei Wan, Guofang Chen, Gongxing Wu, Xide Cheng

“…An improved slime mold algorithm (SMA) was put forward to optimize the interpolating points used in the trajectory modeling. …”
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Psychological interventions for depression among informal caregivers of older adult populations: protocol of a systematic review and meta-analysis of randomised controlled trials by Danelle Pettman, Louise von Essen, Oscar Blomberg, Joanne Woodford, Erika Mårtensson, Renita Sörensdotter

“…Further, the lack of studies targeting adult children specifically necessitates conducting this review targeting caregivers of older adults in general.Methods and analysis Randomised controlled trials of psychological interventions targeting symptoms of depression among informal caregivers will be identified via a systematic search of electronic databases (PubMed, Cumulative Index to Nursing and Allied Health Literature, Excerpta Medica DataBase, PsycINFO, Cochrane Library and Web of Science) and supplemented by handsearching of previous systematic reviews, reference and forward citation checking, and expert contact. If possible, a meta-analysis will be conducted to examine the: (1) effectiveness of psychological interventions for depression among informal caregivers of older adults, (2) effectiveness of psychological interventions for secondary outcomes such as anxiety, stress, caregiver burden, psychological distress, quality of life, well-being and self-efficacy and (3) moderating effects of clinical and methodological factors on effectiveness.Ethics and dissemination Ethical approval will not be necessary for this study given primary data will not be collected. …”
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Beyond averages: dissecting urban-rural disparities in skilled antenatal care utilization in Bangladesh - a conway-maxwell-poisson regression analysis by Md. Muddasir Hossain Akib, Farzana Afroz, Bikash Pal

“…Conclusion Our findings from this study indicate that the concerned authority should come forward, and policymakers should emphasize various factors that are mainly responsible for the noteworthy different SANC status of pregnant women living in rural and urban areas in Bangladesh. …”
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Evaluation of the Rain Effects on Gap Acceptance Behavior at Roundabouts by a Logit Model by Dongmin Lee, Sooncheon Hwang, Eunhan Ka, Chungwon Lee

“…During that time, many ideas have been put forward to improve the safety, operation, and design of such roundabouts. …”
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Design and Test of Combined Air Suction Cotton Breed Seeder by Yudao Li, Zhanhua Song, Fade Li, Yinfa Yan, Fuyang Tian, Xuezhen Sun

“…This paper takes Lumianyan No. 37 as the research object, adopts the single-factor test and the quadratic regression rotation orthogonal test, selects the forward speed, air pressure, and groove plate width of the air suction cup as the experimental factors, and conducts an experiment of the seeder’s performance, by analyzing the influence law of the seeder’s velocity on its seeding variation coefficient. …”
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Nutrigenomics: A promising frontier in chronic disease prevention by Seyed Morteza Hosseiniara, Solmaz Sadat Hosseini Zijoud

“…These include the integration of diverse and complex datasets from various sources -such as genomics, metabolomics, and proteomics- the development of robust bioinformatics tools for data analysis and interpretation, and careful consideration of ethical implications, including privacy concerns and the potential for genetic discrimination.Moving forward, the integration of multi-omics approaches -encompassing a comprehensive analysis of an individual's genetic, epigenetic, metabolic, and proteomic profiles- will be crucial for advancing the field of nutrigenomics. …”
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The effects and durability of an 8-week dynamic neuromuscular stabilization program on balance and coordination in adult males with intellectual disabilities: a randomized controll... by Hamed Babagoltabar-Samakoush, Behnoosh Aminikhah, Saeid Bahiraei

“…Balance and neuromuscular coordination were assessed at baseline, immediately after the intervention, and two months post-intervention using the Balance Error Scoring System (BESS), walking forward heel-to-toe test, and bilateral coordination test. …”
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Translation and validation of the Polish-language version of the Birth Satisfaction Scale-Revised (BSS-R) and its relationship to the type of delivery and the baby’s Apgar score by Paulina Pawlicka, Wiktor Wróbel, Barbara Baranowska, Daria Macewicz, Michał Olech, Caroline J. Hollins Martin, Colin R. Martin

“…Participants and procedure The BSS-R was translated into Polish by an expert panel using forward and backward translation. A complex within-subjects design with an embedded between-subjects component was used to determine the key psychometric characteristics of the PL-BSS-R. …”
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Keratoconus Diagnosis: Validation of a Novel Parameter Set Derived from IOP-Matched Scenario by Dan Lin, Lei Tian, Shu Zhang, Like Wang, Ying Jie, Yongjin Zhou

“…Seventy samples (training set; 35 keratoconus and 35 normal corneas; pairwise matching for IOP) were used to determine NPS by forward logistic regression. A large validation dataset comprising 62 matching samples (31 keratoconus and 31 normal corneas) and 203 unmatching samples (112 keratoconus and 91 normal corneas) was used to evaluate its clinical significance. …”
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