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  1. 67881

    Identification and Spatial Mapping of Locality of Streetscapes in Shanghai Hengfu Historic and Cultural Preservation Area by Yuhan SHAO, Sinan YIN, Dongbo MA, Yuting YIN

    Published 2025-02-01
    “…In addition, the roads with low traffic hierarchy such as branches and alleys are generally rated better than those with high traffic hierarchy in terms of human scale, coherence and permeability.ConclusionThis research may provide a reference for subsequent protection, optimization and development of urban streetscape locality, and may also inspire more large-scale analysis of landscape concepts derived from sociology, anthropology and other disciplines in the future. …”
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  2. 67882

    Impact of glucocorticoids on patients’ quality of life: a qualitative study assessing face validity and feasibility of the Steroid PRO in patients with inflammatory gastroenterolog... by Shaney L Barratt, Emma Dures, Mwidimi Ndosi, Michelle Sharp, Sebastian E Sattui, Jill Dawson, Susan M Goodman, Sarah L Mackie, Tom Creed, Catherine L Hill, Joanna C Robson, Pamela Richards, Susan Bridgewater, Christine A Silverthorne, Jen Orme, Anne-Marie T Sweeney, Elizabeth Arthurs, Genevieve Osborne, Giles Dunhill, Richard P Ramonell, Timothy Patton

    Published 2025-02-01
    “…It has 15 items grouped into 4 domains (Social impact, Impact on Appearance, Psychological Impact and Treatment Concerns). Initially developed and validated in rheumatic diseases, the Steroid PRO demonstrates potential for broader application in patients with other inflammatory conditions. …”
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  3. 67883

    Targeting NANOS1 in triple-negative breast cancer: synergistic effects of digoxin and PD-1 inhibitors in modulating the tumor immune microenvironment by Tangyi Wang, Yadian Lei, Jingwei Sun, Li Wang, Yuxin Lin, Zhijing Wu, Shoude Zhang, Chengzhu Cao, Chengzhu Cao, Chengzhu Cao, Haiyan Wang, Haiyan Wang, Haiyan Wang

    Published 2025-01-01
    “…Researchers may explore FDA-approved drugs targeting the potential target NANOS1 for TOE (Taraxacum officinale extract) treatment to develop innovative therapeutic strategies. In this context, Dig (Digoxin) and AA (Algestone acetophenide) have been identified as potential drug candidates for further exploration of their therapeutic effects and application potential in targeting NANOS1.MethodsRNA sequencing (RNA-seq) was employed to identify potential targets for triple-negative breast cancer (TNBC) from TOE. …”
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  4. 67884
  5. 67885

    Construction of feature selection and efficacy prediction model for transformation therapy of locally advanced pancreatic cancer based on CT, 18F-FDG PET/CT, DNA mutation, and CA19... by Liang Qi, Xiang Li, Jiayao Ni, Yali Du, Qing Gu, Baorui Liu, Jian He, Juan Du

    Published 2025-01-01
    “…Abstract Background Immunotherapy and radiotherapy play crucial roles in the transformation therapy of locally advanced pancreatic cancer; however, the exploration of effective predictive biomarkers has been unsatisfactory. With the rapid development of radiomics, next-generation sequencing, and machine learning, there is hope to identify biomarkers that can predict the efficacy of transformative treatment for locally advanced pancreatic cancer through simple and non-invasive clinical methods. …”
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  6. 67886

    Assessment of Bowel Preparation Using Low-Volume Sulphate-Based Preparations in Comparison with Macrogols: A Multicenter, Randomized, Comparative Clinical Study of the 3rd Phase by E. D. Fedorov, V. V. Veselov, S. V. Kashin, E. V. Tikhomirova, A. V. Veselov, D. V. Zavyalov, A. Kornowski, T. E. Gorskaya, M. Volteau, T. Ponchon

    Published 2019-05-01
    “…The proportion of patients who developed nausea was significantly higher in the OSS group than in the Macrogol group (25.2 % compared with 10.2 % when taking the first dose of the preparation (p = 0.0008) and 19.7 % compared with 6.8 % when taking the second dose of the preparation (p = 0.0016)). …”
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  7. 67887

    Impact of healthy lifestyle on diabetes incidence among adults of different socioeconomic status in Guizhou province: a prospective cohort study by Yiying WANG, Min CHEN, Lieqiang ZHANG, Xin WANG, Wei ZHAN, Yunxi PAN, Xiaodeng ZHAO, Tao LIU

    Published 2024-12-01
    “…Face-to-face interviews with a questionnaire developed by the Chinese Center for Disease Control and Prevention,physical examinations, and laboratory tests were conducted among the residents from November 2010 to December 2012 to collect baseline data, and follow-up surveys were conducted from December 2016 to June 2021. …”
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  8. 67888

    Novel type 2 diabetes prediction score based on traditional risk factors and circulating metabolites: model derivation and validation in two large cohort studiesResearch in context by Ruijie Xie, Christian Herder, Sha Sha, Lei Peng, Hermann Brenner, Ben Schöttker

    Published 2025-01-01
    “…The UK Biobank project was established through collaboration between various entities including the Wellcome Trust, the Medical Research Council, Department of Health, Scottish Government, and the Northwest Regional Development Agency. Additional funding was provided by the Welsh Assembly Government, British Heart Foundation, Cancer Research UK, and Diabetes UK, with support from the National Health Service (NHS). …”
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  9. 67889
  10. 67890

    Evaluation of Some Cumin Ecotypes Based on Selection Index of Ideal Genotype by Masoud Golestani

    Published 2024-11-01
    “…The result of cluster analysis and the SIIG method showed that Sirjan, Kerman, Khatam, Abadeh, and Ardakan were the best ecotypes, which can be used in breeding programs and the cultivation development of this plant. Ashkzar, Shiraz, and Bafgh were the worst ecotypes according to cluster analysis and SIIG values.…”
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  11. 67891
  12. 67892
  13. 67893

    Psychosocial risks and mental health of health and social care workers in the context of the COVID-19 pandemic by Nadia Vilahur Chiaraviglio

    Published 2024-07-01
    “…Many of our certainties in the European continent were shaked by the unequivocal evidence of our vulnerability as individuals and our lack of preparedness as a society to manage a health emergency of unknown boundaries, despite having one of the most well-developed health systems across the globe. Much has been said about COVID-19, but never as I can remember, so much has been said about workers, and occupational safety and health, for once, hit the headlines. …”
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  14. 67894

    Association between major depressive disorder or depressive symptoms and the risk of vascular complications among patients with type 2 diabetes, and the mediating role of metabolic... by Guochen Li, Yongfu Yu, Chunqing Lin, Shichen Zheng, Hong Tu, Wanghong Xu

    Published 2025-01-01
    “…Interpretation: Our findings highlight the role of MDD and depressive symptoms in the development of vascular complications among people with T2DM, and suggest that the effect of improving mental health on vascular outcomes in patients with T2DM should be investigated in future work. …”
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  15. 67895

    Effectiveness of hCMV, mEF1a and mAct promoters on driving of foreign gene expression in transgenic zebrafish by . Alimuddin, G. Yoshizaki, O. Carman, T. Takeuchi

    Published 2007-01-01
    “… Highly unsaturated fatty acids (HUFA), especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have long been recognized for its beneficial effect for human health and development.   The D6 fatty acid desaturase is generally considered to be the rate-limiting factor in HUFA biosynthesis.  …”
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  16. 67896

    Radiotherapy-induced Hypothalamic-Pituitary axis dysfunction in adult Brain, head and neck and skull base tumor patients – A systematic review and Meta-Analysis by J.M.J. Paulissen, C.M.L. Zegers, R.M. Houben, D. Hofstede, M. Kars, H.M. van Santen, F.J.P. Hoebers, D.K.M. De Ruysscher, D.B.P. Eekers

    Published 2025-03-01
    “…Patients irradiated for nasopharyngeal carcinoma (NPC) seemed to be at highest risk for developing any endocrine insufficiency with a mean prevalence of 0.68 (95 % CI 0.45–0.85). …”
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  17. 67897
  18. 67898

    Polimorfisme Gen Apolipoprotein E Pada Penderita Sindrom Down Trisomi 21 by Malinda Meinapuri

    Published 2013-01-01
    “…Polymorphism of APOE gene is related with the increasing of allele ε4’s frequency thus cause obstruction in neuron ramification and development. In previous study, Down Syndrome groups are having different type of APOE gene compared with control. …”
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  19. 67899
  20. 67900

    A key technology for synergistic backfilling of coal-based solid waste and high-salinity wastewater by Shuning DONG, Shujiang YU, Xingling DONG, Buqin ZHANG, Xiaoming GUO, Xiaodong WANG, Kai WANG, Shibin ZHU, Boqiang WU, Lei LIU

    Published 2025-01-01
    “…However, existing technologies for high-salinity wastewater treatment are generally confronted with issues such as great initial investment and high operation costs of the treatment engineering. Methods This study developed a technology for the synergistic treatment of coal-based solid waste and high-salinity wastewater (also referred to as solid-liquid synergistic waste backfilling). …”
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