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Tumor Suppressor Function of CYLD in Nonmelanoma Skin Cancer
Published 2011-01-01“…In basal cell carcinoma, the tumor suppressor protein CYLD is repressed at the transcriptional levels through hedgehog signaling pathway. …”
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Oncogene-tumor suppressor gene feedback interactions and their control
Published 2015-07-01Subjects: Get full text
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ROLE OF HETEROZYGOUS TUMOR SUPPRESSORS IN THE LIFE LONGEVITY OF DROSOPHILA MELANOGASTER
Published 2015-01-01Subjects: Get full text
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4
Glutamine missense suppressor transfer RNAs inhibit polyglutamine aggregation
Published 2025-03-01“…Cells expressing the missense suppressor tRNAs showed no cytotoxic effects and no defects in growth or global protein synthesis levels. …”
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5
Myeloid-Derived Suppressor Cells Participate in Preventing Graft Rejection
Published 2012-01-01“…Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells and have a tremendous potential to suppress immune responses. …”
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Macrophages, Inflammation, and Tumor Suppressors: ARF, a New Player in the Game
Published 2012-01-01“…In this paper, we provide an overview of the immunobiology of TAMs as well as what is known about tumor suppressors in the context of immune responses. Recent advances regarding the role of the tumor suppressor ARF as a regulator of inflammation and macrophage polarization are also reviewed.…”
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Role of T Regulatory Cells and Myeloid-Derived Suppressor Cells in COVID-19
Published 2022-01-01“…Immunosuppressive cells including T regulatory cells (Tregs) and myeloid-derived suppressor cells (MDSCs) are key players in immunological tolerance and immunoregulation; however, they contribute to the pathogenesis of different diseases including infections. …”
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Immunosuppressive Role of Myeloid-Derived Suppressor Cells and Therapeutic Targeting in Lung Cancer
Published 2018-01-01“…Immunotherapy is becoming more and more encouraging and promising in lung cancer therapy. Myeloid-derived suppressor cells (MDSCs) are the main tumor suppressor factors, and the treatment strategy of targeting MDSCs is gradually emerging. …”
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Axial-Symmetry Numerical Approaches for Noise Predicting and Attenuating of Rifle Shooting with Suppressors
Published 2011-01-01“…Five cases of gunshot including one model of an unsuppressed rifle and four models of suppressors were simulated. Besides, serial images of species distributions and velocity vectors-pressure contours in suppressors and near muzzle field were displayed. …”
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Targeting Myeloid-Derived Suppressor Cells Is a Novel Strategy for Anti-Psoriasis Therapy
Published 2020-01-01“…Our data suggest that targeting myeloid-derived suppressor cells is a novel strategy for antipsoriasis therapy. …”
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Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans.
Published 2004-10-01“…The von Hippel-Lindau (VHL) tumor suppressor functions as a ubiquitin ligase that mediates proteolytic inactivation of hydroxylated alpha subunits of hypoxia-inducible factor (HIF). …”
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13
Sustainable mortar with waste glass fine aggregates and pond ash as an alkali-silica reaction suppressor
Published 2025-07-01Get full text
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The Crosstalk between Myeloid Derived Suppressor Cells and Immune Cells: To Establish Immune Tolerance in Transplantation
Published 2016-01-01“…Myeloid derived suppressor cells (MDSCs) are a heterogeneous population of myeloid precursor and progenitor cells and endowed with a robust immunosuppressive activity in multiple pathophysiological conditions. …”
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Suppressors of Cytokine Signaling 3 Expression in Eosinophils: Regulation by PGE2 and Th2 Cytokines
Published 2011-01-01“…Asthma and nonasthmatic eosinophilic bronchitis (NAEB) are respiratory disorders characterized by a predominance of Th2 cells and eosinophilic inflammation. Suppressors of cytokine signaling (SOCS) proteins play an important role in Th2-mediated allergic responses through control of the balance between Th1 and Th2 cells, particularly, SOCS3 and SOCS5. …”
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TNRC6C Functions as a Tumor Suppressor and Is Frequently Downregulated in Papillary Thyroid Cancer
Published 2021-01-01“…Our previous study found that trinucleotide repeat containing adaptor 6C (TNRC6C) may act as a tumor suppressor in papillary thyroid cancer (PTC). In this study, we aimed to confirm the effect of TNRC6C on PTC and investigate the underlying molecular mechanism. …”
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Protein tyrosine phosphatase delta is a STAT3-phosphatase and suppressor of metabolic liver disease
Published 2025-01-01Get full text
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MicroRNA in Cervical Cancer: OncomiRs and Tumor Suppressor miRs in Diagnosis and Treatment
Published 2014-01-01Get full text
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Bone Marrow Neutrophils of Multiple Myeloma Patients Exhibit Myeloid-Derived Suppressor Cell Activity
Published 2021-01-01“…Activated normal density granulocytes (NDGs) can suppress T-cell responses in a similar way as myeloid-derived suppressor cells (MDSCs). In this study, we tested the hypothesis that NDGs from blood and bone marrow of multiple myeloma (MM) patients have the ability to suppress T-cells, as MDSC. …”
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TET1 is a Tumor Suppressor That Inhibits Papillary Thyroid Carcinoma Cell Migration and Invasion
Published 2020-01-01Get full text
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