Coalgebraic Structure of Genetic Inheritance by Jianjun Tian, Bai-Lian Li

“…Mathematically, to constructphylogenetic trees means we need to solve equations x[n]=a, or x(n)=b. It is generally impossible tosolve these equations in algebras. …”
Get full text

Benchmarking protein language models for protein crystallization by Raghvendra Mall, Rahul Kaushik, Zachary A. Martinez, Matt W. Thomson, Filippo Castiglione

“…Abstract The problem of protein structure determination is usually solved by X-ray crystallography. Several in silico deep learning methods have been developed to overcome the high attrition rate, cost of experiments and extensive trial-and-error settings, for predicting the crystallization propensities of proteins based on their sequences. …”
Get full text

An unbiased cell morphology-based screen for new, biologically active small molecules. by Masahiro Tanaka, Raynard Bateman, Daniel Rauh, Eugeni Vaisberg, Shyam Ramachandani, Chao Zhang, Kirk C Hansen, Alma L Burlingame, Jay K Trautman, Kevan M Shokat, Cynthia L Adams

“…We used affinity purification to identify a target of hydroxy-PP, carbonyl reductase 1 (CBR1), a short-chain dehydrogenase-reductase. We solved the X-ray crystal structure of the CBR1/hydroxy-PP complex to 1.24 A resolution. …”
Get full text

Synthesis, Characterization, and Catalytic Studies of Mn(III)-Schiff Base-Dicyanamide Complexes: Checking the Rhombicity Effect in Peroxidase Studies by Manuel R. Bermejo, Rocío Carballido, M. Isabel Fernández-García, Ana M. González-Noya, Gustavo González-Riopedre, Marcelino Maneiro, Laura Rodríguez-Silva

“…The crystal structure of H2L2 in solid state, solved by X-ray crystallography, is highly conditioned in the solid state by two N-H•••N intramolecular interactions. …”
Get full text