Diplomacy and Recruitment of Mercenaries before the Battle of Žalgiris by Sven Ekdahl

“…He had regarded such an attack as legitimate, because the Poles had rejected the arbitration by King Venceslas, and had for that purpose secretly recruited 1,800 mercenaries. Now his war machinery had been brought to a standstill by his mighty ally. …”
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The Effect of Feeding Different Levels of Mineral Biochar on Performance, Blood Parameters, Production and Milk Composition of Holstein Dairy Cows by Ali Khatibi Bardsiri, Reza Valizadeh, Seyed Hadi Ebrahimi, Pirouz Shakeri, Abbas Ali Naserian

“…Considering that the origin of the metabolic biosynthesis process of protein in milk is due to amino acids in the blood reaching the mammary tissue, and that the energy needed for this metabolic pathway is provided by glucose (absorbed from the small intestine or derived from propionic acid produced in the rumen), the amount of milk protein is determined by the total amount of casein protein, albumins, and blood immunoglobulins secreted in milk. The evaluation of the amounts and ratios of glucose, protein, and blood albumin showed that the highest levels of glucose, protein, and albumin in blood plasma were observed in the treatment fed with a basic diet supplemented with 0.5% biochar. …”
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Effect and Mechanism of Electroacupuncture at the Affected Side of Quchi （LI 11） and Yanglingquan （GB 34） Acupoints in Rats with Limb Spasms after Cerebral Infarction by ZHAN Sheng, HUANG Linxing, YI Lizhen, CHEN Ruixue, HUANG Huiyuan, YUE Zenghui

“…Compared with the model group, expression level of RFK and NOX2 protein and the transcription level of RFK and NOX2 mRNA in the electroacupuncture group decreased significantly after treatment (<italic>P</italic>&lt;0.05).ConclusionElectroacupuncture can improve neurological impairment and limb spasm in rats with PSS, and its mechanism may be to the reduction down-regulation of Glu content in the cortex, reduction of the secretion of inflammatory cytokines TNF-α and IL-6, the inhibition of RFK and NOX2 expression, and the reduction of oxidative stress levels.…”
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LRH‐1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype by Nadia Cobo‐Vuilleumier, Silvia Rodríguez‐Fernandez, Livia López‐Noriega, Petra I. Lorenzo, Jaime M. Franco, Christian C. Lachaud, Eugenia Martin Vazquez, Raquel Araujo Legido, Akaitz Dorronsoro, Raul López‐Férnandez‐Sobrino, Beatriz Fernández‐Santos, Carmen Espejo Serrano, Daniel Salas‐Lloret, Nila vanOverbeek, Mireia Ramos‐Rodriguez, Carmen Mateo‐Rodríguez, Lucia Hidalgo, Sandra Marin‐Canas, Rita Nano, Ana I. Arroba, Antonio Campos Caro, Alfred CO Vertegaal, Alejandro Martín‐Montalvo, Franz Martín, Manuel Aguilar‐Diosdado, Lorenzo Piemonti, Lorenzo Pasquali, Roman González Prieto, Maria Isabel García Sánchez, Decio L. Eizirik, Maria Asuncion Martínez‐Brocca, Marta Vives‐Pi, Benoit R. Gauthier

“…Results LRH‐1/NR5A2 activation induced a genetic and immunometabolic reprogramming of T1D immune cells, marked by reduced pro‐inflammatory markers and cytokine secretion, along with enhanced mitohormesis in pro‐inflammatory M1 macrophages and mitochondrial turnover in mature dendritic cells. …”
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The Role of Potassium Phosphite in Enhancing the Activity of Defense Enzymes in Rice Infected by Sheath Blight by Milad Habibi Daronkolaei, Mohammad Ali Tajick Ghanbary, Valiollah Babaeizad, Heshmatollah Rahimian, Ali Dehestani

“…R. solani induces cell death in plants by secreting enzymes and toxins. Potassium phosphite inhibits cell death by enhancing the activity of antioxidant enzymes, such as CAT, PPO, and SOD, thereby impeding the progression of the fungus. …”
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In vitro functional validation of anti-CD19 chimeric antigen receptor T cells expressing lysine-specific demethylase 1 short hairpin RNA for the treatment of diffuse large B cell l... by Zhi Guo, Zhi Guo, Mingxin He, Ning Liu, Yiqing Yang, Rui Sun, Jianxun Wang, Qiang Wang

“…We further found that LSD1 shRNA anti-CD19 CAR-T cells secreted more IFN-γ and granzyme B than RNAU6 anti-CD19 CAR-T cells. …”
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miR-317 regulates the proliferation and apoptosis of duck follicle granulosa cells by targeting VIPR1 by Li Li, Qingwu Xin, Linli Zhang, Zhongwei Miao, Zhiming Zhu, Xiaopan Liu, Qiannan Cai, Wenli Shi, Bangzhe Zhao, Changtao Liu, Zhengkui Zhou, Azheng Liang, Qinlou Huang, Nenzhu Zheng

“…VIPR1 can specifically bind VIP, a PRL release factor, which promotes the secretion of PRL from the pituitary gland, and participates in the regulation of bird nesting behavior. …”
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Genetic environmental interaction to achieve optimum physiological states of crossbred cattle in tropical climate by A. Aryogi, L. Affandhy, D. Pamungkas, S. Setiasih, Y.N. Anggraeny, P.W. Prihandini, P.R. Matitaputty, I.N. Suyasa, S. Rusdiana, D.T. Ramsiati, W.I Wulansari, M. Chanafi, D.K. Robba, M. Luthfi

“…It sheds light on how this interaction influences the physiological and reproductive capabilities of the cattle, as well as the alterations in reproductive hormone secretion within this specific population. The results will serve as the main consideration for the development of crossbred cattle in tropical climates.METHODS: A fully randomized design incorporating three variables was employed in this study: altitude (highland and lowland), cattle breed (crossbred and local), and observation time. …”
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Pien Tze Huang Attenuates Neuro-inflammatory Injury in BV2 Microglial Cells Induced by Lipopolysaccharide via Inhibition of TLR4/MAPK Signaling Pathway by Zhenwei HUANG, Qing ZHANG, Lili HUANG, Xiaoqin ZHANG, Mingqing HUANG

“…Then the protein expression of TLR4, ERK1/2, p-ERK1/2, p38, p-p38, JNK, p-JNK, COX-2, iNOS in BV2 microglial cells were detected by Western blot.Results:1) The result of MTT assay showed that PZH at 0.05-0.15 mg/mL concentration and LPS at 100 ng/mL concentration had no significant cytotoxicity on BV2 microglial cells (<italic>P</italic>&gt; 0.05).2) The result of ELISA showed that the secretion of IL-6 was significantly increased in BV2 microglial cells induced by LPS compared with the normal control group (<italic>P</italic>&lt; 0.001); compared with the LPS group, different concentrations of PZH significantly decreased the expression level of IL-6 in LPS-induced BV2 microglial cells (<italic>P</italic>&lt; 0.05, <italic>P</italic>&lt; 0.05, <italic>P</italic>&lt; 0.01).3) The result of RT-qPCR showed that the transcriptional levels of IL-1β(<italic>P</italic>&lt; 0.001), IL-6(<italic>P</italic>&lt; 0.001) and TNF-α(<italic>P</italic>&lt; 0.01) were significantly increased after the induction of LPS compared with normal controal group; different concentrations of PZH significantly inhibited the LPS-induced IL-1β(<italic>P</italic>&lt; 0.05, <italic>P</italic>&lt; 0.01, <italic>P</italic>&lt; 0.001), IL-6(<italic>P</italic>&gt; 0.05, <italic>P</italic>&lt; 0.01, <italic>P</italic>&lt; 0.001) and TNF-α(<italic>P</italic>&lt; 0.01, <italic>P</italic>&lt; 0.01, <italic>P</italic>&lt; 0.001) mRNA upregulation.4) The result of Western blot showed that PZH significantly inhibited the LPS-induced TLR4/MAPK signaling pathway activation, and decreased the protein expressions of TLR4(<italic>P</italic>&gt; 0.05, <italic>P</italic>&lt; 0.05, <italic>P</italic>&lt; 0.05), p-ERK1/2(<italic>P</italic>&gt; 0.05, <italic>P</italic>&lt; 0.05, <italic>P</italic>&lt; 0.01), p-p38(<italic>P</italic>&lt; 0.05, <italic>P</italic>&lt; 0.01, <italic>P</italic>&lt; 0.01), COX-2(<italic>P</italic>&lt; 0.01, <italic>P</italic>&lt; 0.01, <italic>P</italic>&lt; 0.001) and iNOS(<italic>P</italic>&lt; 0.01, <italic>P</italic>&lt; 0.01, <italic>P</italic>&lt; 0.01), but not p-JNK.Conclusion:PZH can significantly improve the LPS-induced neuro-inflammatory injury, which may be related to the inhibition of the activation of TLR4/MAPK signaling pathway.…”
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The Role of Iranians in Istanbul in Publishing and Distributing Modernist and Constitutionalist Texts by Mohammad Hossein Sadeghi, Hassan Hazrati

“…In the suffocating atmosphere of Hamidian despotism, they acted with difficulty and in most cases secretly; however, they faced less sensitivity than their Ottoman counterparts. …”
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Designing a security-oriented leadership model of Mazandaran University of Medical Sciences by Saeid Miladigorji, Mohammad Hassan Shakki, Mojtaba Rezaei Rad

“…This style of leadership can facilitate the possibility of efficient and productive intra-organizational cooperation, because in such organizations, communication flows parallel to trust. It is no secret that most of today's organizations struggle with various issues, including technological developments, resource limitations, energy problems, etc. …”
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Selected Abstracts of the 20th International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 23-26, 2024 by --- Various Authors

“…Leiner (El Paso, Texas, USA) ABS 2. L1CAM IS SECRETED THROUGH EXOSOMES IN THE DEVELOPING HUMAN BRAIN • F. …”
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