What are the lived healthcare experiences of patients with primary sclerosing cholangitis? A community-based qualitative interview study by Sheila Greenfield, Gideon Hirschfield, Jayne Parry, Katherine Arndtz, Madeline Cameron

“…This study aimed to explore the experiences of patients with PSC regarding their disease and healthcare.Design A series of semi-structured interviews was completed with patients with PSC, including questioning their experiences of living with PSC and its related healthcare.Setting Participants were recruited from communities in England, Scotland and Wales, with advertisement via PSC Support (UK disease-specific charity support group).Participants 18 patients aged between 21 and 72 years were interviewed; 10 were male (56%), and all were of Caucasian ethnicity. …”
Get full text

From fragmented to integrated healthcare managing hypertension post-stroke: a qualitative study by Hala F. Azhari, Jonathan Hewitt, Martin O'Neill, Alexander Smith, Terence Quinn, Jesse Dawson

“…This study explores the perspectives of stroke survivors and healthcare professionals on hypertension management and evaluates the acceptability of innovative strategies, including 24-h ambulatory blood pressure monitoring (ABPM).MethodsA qualitative study using grounded theory methodology was conducted through focus group interviews with stroke survivors and healthcare professionals in Wales and Scotland between January 2019 and December 2022. Participants included 48 individuals representing diverse backgrounds and experiences. …”
Get full text

Sexual and reproductive health and rights, HIV and migration in southern Africa: A rapid review by G Musuka, I Chingombe, E Moyo, T Chikava, B Moyo, M Mapingure, H Musuka, T Dzinamarira

Get full text

DEPEND study protocol: early detection of patients with pancreatic cancer – a pilot study to evaluate the utility of faecal elastase-1 and 13C-mixed triglyceride breath test as scr... by Christopher D Byrne, Sam Wilding, Paul Remi Afolabi, Declan McDonnell, Victoria Goss, Jocelyn Walters, Zaed Z Hamady

“…Potential biomarkers of PC showing abilities to discriminate between patients with PC from healthy subjects or patients with chronic pancreatitis will be selected by metabolomic analysis.Ethics and dissemination The study was approved by the North of Scotland Research and Ethics Committee on 1 October 2020 (reference: 20/NS/0105, favourable opinion granted). …”
Get full text

MAPPING OF THE LOCI CONTROLLING THE RESISTANCE TO PYRENOPHORA TERES F. TERES AND COCHLIOBOLUS SATIVUS IN TWO DOUBLE HAPLOID BARLEY POPULATIONS by O. S. Afanasenko, A. V. Koziakov, P. Hedlay, N. M. Lashina, A. V. Anisimova, O. Manninen, M. Jalli, E. K. Potokina

Get full text

Teaching undergraduate medical students virtual consultation skills: a mixed-methods interventional before-and-after study by Edie Booth, Kate McFetridge, Evelyn Ferguson, Catherine Paton

“…Objectives To evaluate the impact and transferability of a novel teaching method on virtual communication skills for final year medical students.Design Mixed-methods, interventional before-and-after study.Setting NHS Lanarkshire, Scotland.Participants 21 final year medical students on their obstetrics and gynaecology (O&G) placement from September to December 2020.Interventions A two-part teaching session on virtual communication skills.Main outcome measures Self-reported confidence in conducting consultations preteaching and post-teaching, exposure to virtual consultations, usefulness of teaching and transferability to primary care. …”
Get full text

Hypertensive load predicts recovery of renal function for patients undergoing revascularisation for renal artery stenosis by Ben Edgar, Rob Pearson, Andrew Jackson, Callum Stove, Ram Kasthuri, Keith Hussey, Christian Delles, Colin Geddes, Patrick Mark, Giles Roditi, Linsay McCallum, David B. Kingsmore

“…A retrospective analysis was performed of all patients who had renal revascularisation for renal impairment in a defined geographical area (West of Scotland, population 2.4 million) between 2008 and 2024. …”
Get full text

The Impact of Changes in Corneal Back Surface Astigmatism on the Residual Astigmatic Refractive Error following Routine Uncomplicated Phacoemulsification by Larysa Tutchenko, Sudi Patel, Oleksiy Voytsekhivskyy, Mykhailo Skovron, Olha Horak

Get full text

Teachers’ responses to racism and racist bullying in Dutch primary schools by Karen M. A. Sieben-Aduful, Roy A. Willems, Trijntje Völlink, Nico van der Wiel, Maria Sapouna, Pieter de Bruijn, Gemma Blok, Gemma Blok, Arjan E. R. Bos, Arjan E. R. Bos, Giel van Lankveld

Get full text

Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones by Lisa Ivatt, Mhairi Paul, Allende Miguelez-Crespo, Patrick W. F. Hadoke, Matthew A. Bailey, Ruth A. Morgan, Mark Nixon

Get full text

Highlights of the Fourth Canadian Symposium on Hepatitis C: Moving towards a National Action Plan by Selena M. Sagan, Benoit Dupont, Jason Grebely, Mel Krajden, Sonya A. MacParland, Jennifer F. Raven, Sahar Saeed, Jordan J. Feld, D. Lorne Tyrrell, Joyce A. Wilson

“…The United States, Australia, and Scotland all have National Action Plans to prevent, diagnose, and treat HCV in order to efficiently reduce the burden and costs associated with HCV-related liver disease. …”
Get full text

Occult hepatitis B virus infection: risk for a blood supply, but how about individuals’ health? by Michael X. Fu, Ahmed Elsharkawy, Brendan Healy, Celia Jackson, Daniel Bradshaw, Emma Watkins, Ines Ushiro-Lumb, Jaisi Griffiths, James Neuberger, Kathryn Maguire, Monica Desai, Neil McDougall, Nicole Priddee, Stephen T. Barclay, Stuart Blackmore, Peter Simmonds, William L. Irving, Heli Harvala

Get full text

First-Line Chemo-Immunotherapy in SCLC: Outcomes of a Binational Real-World Study by Laura Moliner, MD, Núria Zellweger, MSc, Sabine Schmid, MD, Martina Bertschinger, MD, Christine Waibel, MD, Ferdinando Cerciello, MD, PhD, Patrizia Froesch, MD, Michael Mark, MD, Adrienne Bettini, MD, Pirmin Häuptle, MD, Veronika Blum, MD, Lisa Holer, MSc, Stefanie Hayoz, PhD, Martin Früh, MD, Samreen Ahmed, FRCP, MD, MBBS, MSc, Shradha Bhagani, MD, Nicola Steele, MD, Hannah-Leigh Gray, BSc, Stephen D. Robinson, MD, Michael Davidson, MD (Res), Samantha Cox, MD, MSc, MBBCh, Taha Khalid, MD, Tom R. Geldart, MD, Luke Nolan, FRCS, PhD, Deborah C. Scott, MBChB (MRCP), Lindsay Hennah, MD, Tom Newsom-Davis, MD, PhD, Emma Rathbone, MD, PhD, Catherine Handforth, MD, Arshi Denton, MD, Shairoz Merchant, PhD, Fiona Blackhall, MD, PhD, Laetitia A. Mauti, MD, Raffaele Califano, MD, Sacha I. Rothschild, MD, PhD

Get full text

Metabolomics Biomarkers in Prediction of Sudden Infant Death Syndrome: The Role of Short Chain Fatty Acids by Maria Aslam, Omer Riaz, Jawaria Aslam, Dost Muhammad Khan, Mustafa Hameed, Muhammad Suleman, Rizwan Shahid, Turke Althobaiti, Naeem Ramzan

Get full text

Novel adaptive immune systems in pristine Antarctic soils by Marc W. Van Goethem, Oliver K. I. Bezuidt, Rian Pierneef, Surendra Vikram, David W. Hopkins, Thomas Aspray, Grant Hall, Stephan Woodborne, Ian D. Hogg, Trent R. Northen, Weidong Kong, Daniele Daffonchio, Don A. Cowan, Yves Van de Peer, Manuel Delgado-Baquerizo, Thulani P. Makhalanyane

Get full text

Microbes Saving Lives and Reducing Suffering by Kenneth Timmis, Zeynep Ceren Karahan, Juan Luis Ramos, Omry Koren, Ana Elena Pérez‐Cobas, Karen Steward, Victor deLorenzo, Elisabetta Caselli, Margaret Douglas, Clarissa Schwab, Virginia Rivero, Rafael Giraldo, Junkal Garmendia, Raymond J. Turner, Jessamyn Perlmutter, José M. Borrero de Acuña, Pablo Ivan Nikel, Jerome Bonnet, Angela Sessitsch, James K. Timmis, Carla Pruzzo, M. Auxiliadora Prieto, Siavash Isazadeh, Wei E. Huang, Gerard Clarke, Danilo Ercolini, Max Häggblom

Get full text

Evaluation of two electronic-rehabilitation programmes for persistent knee pain: protocol for a randomised feasibility trial by Philip G Conaghan, Kim L Bennell, Mark Conner, Rana S Hinman, Sarah R Kingsbury, Elizabeth M A Hensor, Gretl A McHugh, Christine Comer, Dawn Groves-Williams, Rachel K Nelligan

“…If considered feasible and acceptable, a definitive randomised controlled trial can be conducted to investigate the clinical effectiveness and cost-effectiveness of one or both interventions with a view to implementation in routine care.Ethics and dissemination The trial was approved by the West of Scotland Research Ethics Committee 5 (Reference: 20/WS/0006). …”
Get full text

Inequalities in physical comorbidity: a longitudinal comparative cohort study of people with severe mental illness in the UK by Tim Doran, Darren M Ashcroft, Evangelos Kontopantelis, David Reeves, Siobhan Reilly, Claire Planner, Ivan Olier, Linda Gask

“…We calculated the prevalence of SMI by UK country, English region and deprivation quintile, antipsychotic and antidepressant medication prescription rates for people with SMI, and prevalence rates of common comorbidities in people with SMI compared with people without SMI.Design Retrospective cohort study from 2000 to 2012.Setting 627 general practices contributing to the Clinical Practice Research Datalink, a UK primary care database.Participants Each identified case (346 551) was matched for age, sex and general practice with 5 randomly selected control cases (1 732 755) with no diagnosis of SMI in each yearly time point.Outcome measures Prevalence rates were calculated for 16 conditions.Results SMI rates were highest in Scotland and in more deprived areas. Rates increased in England, Wales and Northern Ireland over time, with the largest increase in Northern Ireland (0.48% in 2000/2001 to 0.69% in 2011/2012). …”
Get full text

Assessment of the validity and reliability of the nurses’ professional values scale—revised in Persian version among nursing students by Fahimeh Alsadat Hosseini, Ladan Zarshenas, Kobra Parvan, Maryam Shaygan, Banafsheh Tehranineshat, Brian Thomson

Get full text

Segmental analysis of human hair reveals intra-annual variation in 25(OH)D3 concentrations in modern and archaeological individuals by Kate Britton, Orsolya Czére, Eléa Gutierrez, Linda M. Reynard, Eamon Laird, Gary Duncan, Baukje de Roos

“…Here, we determined 25(OH)D3 concentrations in hair specimens (‘locks’) that had been sampled close to the root, aligned by cut end, and sliced into sequential segments from participants (n = 16), from Aberdeen, Scotland, using a modified protocol designed to minimise sample size. …”
Get full text