Brain expression—is it all in our SNPs? by Philipp Khaitovich

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Assessing the Effect of SNPs on Litter Traits in Pigs by Lyubov V. Getmantseva, Siroj Yu Bakoev, Varvara S. Shevtsova, Anatoly Yu Kolosov, Neckruz F. Bakoev, Maria A. Kolosova

“…The reproductive ability of sows is the principle of continuous and efficient production, based on such traits as the number of piglets, the total number of parities, and the period of economic use. Currently, SNPs associated with the TNB and NBA are presented in the PigQTLdb. …”
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All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs. by Andrew J Schork, Wesley K Thompson, Phillip Pham, Ali Torkamani, J Cooper Roddey, Patrick F Sullivan, John R Kelsoe, Michael C O'Donovan, Helena Furberg, Tobacco and Genetics Consortium, Bipolar Disorder Psychiatric Genomics Consortium, Schizophrenia Psychiatric Genomics Consortium, Nicholas J Schork, Ole A Andreassen, Anders M Dale

“…We show a consistent pattern of enrichment of polygenic effects in specific annotation categories across diverse phenotypes, with the greatest enrichment for SNPs tagging regulatory and coding genic elements, little enrichment in introns, and negative enrichment for intergenic SNPs. …”
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The SNP’s Conception of Scottish Society and Citizenship, 2007-2014 by Nathalie Duclos

“…These visions of society and citizenship were all included in the SNP’s case for an independent social democratic Scottish State.…”
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A genome-wide investigation of SNPs and CNVs in schizophrenia. by Anna C Need, Dongliang Ge, Michael E Weale, Jessica Maia, Sheng Feng, Erin L Heinzen, Kevin V Shianna, Woohyun Yoon, Dalia Kasperaviciūte, Massimo Gennarelli, Warren J Strittmatter, Cristian Bonvicini, Giuseppe Rossi, Karu Jayathilake, Philip A Cola, Joseph P McEvoy, Richard S E Keefe, Elizabeth M C Fisher, Pamela L St Jean, Ina Giegling, Annette M Hartmann, Hans-Jürgen Möller, Andreas Ruppert, Gillian Fraser, Caroline Crombie, Lefkos T Middleton, David St Clair, Allen D Roses, Pierandrea Muglia, Clyde Francks, Dan Rujescu, Herbert Y Meltzer, David B Goldstein

“…We report a genome-wide assessment of single nucleotide polymorphisms (SNPs) and copy number variants (CNVs) in schizophrenia. …”
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Combinations of SNPs related to signal transduction in bipolar disorder. by Pernille Koefoed, Ole A Andreassen, Bente Bennike, Henrik Dam, Srdjan Djurovic, Thomas Hansen, Martin Balslev Jorgensen, Lars Vedel Kessing, Ingrid Melle, Gert Lykke Møller, Ole Mors, Thomas Werge, Erling Mellerup

“…Thus, in analysis of many SNPs in association studies of complex diseases, it may be useful to look at combinations of genotypes. …”
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Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations? by Amanda M Casto, Marcus W Feldman

“…We apply these same techniques to evaluate SNPs grouped by trait association. We find that groups of SNPs associated with pigmentation, blood pressure, infectious disease, and autoimmune disease traits exhibit unusual allele frequency patterns and elevated iHS scores in certain geographical locations. …”
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Screening and Evaluation of Deleterious SNPs in APOE Gene of Alzheimer’s Disease by Tariq Ahmad Masoodi, Sulaiman A. Al Shammari, May N. Al-Muammar, Adel A. Alhamdan

“…The objective of this study is to identify deleterious nsSNPs associated with APOE gene. Methods. The SNPs were retrieved from dbSNP. …”
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Sex-heterogeneous SNPs disproportionately influence gene expression and health. by Michela Traglia, Margaux Bout, Lauren A Weiss

“…Biometric trait sex-heterogeneous SNPs (sex-het SNPs) showed enrichment in association signals for 20 out of 33 diseases/traits at 5% alpha compared to sex-homogeneous matched SNPs (empP < 0.001), and were significantly overrepresented in muscle, skeletal and stem cell development processes, and in calcium channel and microtubule complexes (FDR < 0.05, empP < 0.05). …”
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Determination of damaging SNP’s in SHANK3 gene with in silico methods by İrem Gülfem Albayrak, Şeyma Yektar, Süeda Kaya

“…After the analysis, from the NCBI dbSNP database, 1535 missense SNPs in the SHANK3 gene were identified, with 54 classified as deleterious. …”
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In Silico Analysis of BMAL1 and CLOCK SNPs in the Ensembl Database by Şeref Gül

“…Several PER2 and CRY2 SNPs are associated with advanced sleep phase syndrome. …”
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Influence of ATG SNPs on hip fracture patients’ functional status by Carmen da Casa, Carlos Gutiérrez-Cerrajero, Carmen Pablos, M. Agustina Hierro-Estévez, Alfonso González-Ramírez, David Briz, Rogelio González-Sarmiento, Juan F. Blanco

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Data-driven projections of candidate enhancer-activating SNPs in immune regulation by Markus Hoffmann, Tiago Vaz, Shreeti Chhatrala, Lothar Hennighausen

“…Abstract Background Millions of single nucleotide polymorphisms (SNPs) have been identified in humans, but the functionality of almost all SNPs remains unclear. …”
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Semantic Modeling for SNPs Associated with Ethnic Disparities in HapMap Samples by HyoYoung Kim, Won Gi Yoo, Junhyung Park, Heebal Kim, Byeong-Chul Kang

“…Single-nucleotide polymorphisms (SNPs) have been emerging out of the efforts to research human diseases and ethnic disparities. …”
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Scrutinizing Deleterious Nonsynonymous SNPs and Their Effect on Human POLD1 Gene by Md. Nazmul Islam Bappy, Anindita Roy, Md Gulam Rabbany Rabbi, Nusrat Jahan, Fahmida Akther Chowdhury, Syeda Farjana Hoque, Emran Hossain Sajib, Parvez Khan, Ferdaus Mohd Altaf Hossain, Kazi Md. Ali Zinnah

“…The consequence of missense or nonsynonymous SNPs (nsSNPs), which occur in the coding region of a specific gene, is the replacement of single amino acid. …”
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Computational prediction of deleterious nonsynonymous SNPs in the CTNS gene: implications for cystinosis by Leila Adda Neggaz, Amira Chahinez Dahmani, Ibtissem Derriche, Nawel Adda Neggaz, Abdallah Boudjema

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The classification method of donkey breeds based on SNPs data and machine learning by Dekui Li, Dekui Li, Xiaolong Hu, Yongdong Peng

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Exploring the association between SNPs and facial morphology in a Spanish population by Belén Navarro-López, Franziska Wilke, Victoria Suárez-Ulloa, Miriam Baeta, Rubén Martos-Fernández, Olatz Moreno-López, Iñigo Olalde, Begoña Martínez-Jarreta, Susana Jiménez, Susan Walsh, Marian M. de Pancorbo

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Heritability and genetic correlations explained by common SNPs for metabolic syndrome traits. by Shashaank Vattikuti, Juen Guo, Carson C Chow

“…We found the percentage of h(2) accounted for by common SNPs to be 58% of h(2) for height, 41% for BMI, 46% for WHR, 30% for GLU, 39% for INS, 34% for TG, 25% for HDL, and 80% for SBP. …”
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Optimized in-solution enrichment of over a million ancient human SNPs by Roberta Davidson, Xavier Roca-Rada, Shyamsundar Ravishankar, Leonard Taufik, Christian Haarkötter, Evelyn Collen, Matthew P. Williams, Peter Webb, M. Irfan Mahmud, Erlin Novita Idje Djami, Gludhug A. Purnomo, Cristina Santos, Assumpció Malgosa, Linda R. Manzanilla, Ana Maria Silva, Sofia Tereso, Vítor Matos, Pedro C. Carvalho, Teresa Fernandes, Anne-France Maurer, João C. Teixeira, Raymond Tobler, Lars Fehren-Schmitz, Bastien Llamas

“…Results We find that the “Twist Ancient DNA” assay provides robust enrichment of approximately 1.2M target SNPs without introducing allelic bias that may interfere with downstream population genetics analyses. …”
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