Receptor for Advanced Glycation End Products and Its Involvement in Inflammatory Diseases by Yaw Kuang Chuah, Rusliza Basir, Herni Talib, Tung Hing Tie, Norshariza Nordin

“…RAGE signaling and downstream pathways have been implicated in a wide spectrum of inflammatory-related pathologic conditions such as arteriosclerosis, Alzheimer's disease, arthritis, acute respiratory failure, and sepsis. Despite the significant progress in other RAGE studies, the functional importance of the receptor in clinical situations and inflammatory diseases still remains to be fully realized. …”
Get full text

PLAC8 attenuates pulmonary fibrosis and inhibits apoptosis of alveolar epithelial cells via facilitating autophagy by Wei Sun, Bo Zhao, Zhong He, Lihua Chang, Wei Song, Yingying Chen

“…Abstract Idiopathic pulmonary fibrosis (IPF) is an irreversible lung condition that progresses over time, which ultimately results in respiratory failure and mortality. In this study, we found that PLAC8 was downregulated in the lungs of IPF patients based on GEO data, in bleomycin (BLM)-induced lungs of mice, and in primary murine alveolar epithelial type II (pmATII) cells and human lung epithelial cell A549 cells. …”
Get full text

A Fatal Case of Diffuse Alveolar Hemorrhage in the Setting of Systemic Lupus Erythematosus: A Case Report and Review of Noninfectious Causes of Acute Pulmonary Hemorrhage in Adults by Mia C. Lundgren, Jerry A. Molitor, Benjamin Spilseth, Oyedele Adeyi

“…We present a case of a patient with dyspnea on exertion, dry coughs, lower extremity edema, and intermittent periorbital edema who ultimately succumbed to respiratory failure secondary to DAH in the setting of SLE. …”
Get full text

A Rare Case of Squamous Cell Carcinoma of the Bladder Presenting as a Metastatic Right Ventricular Mass by Joanna M. Bonsall, Rhome Hughes, Mario Mosunjac, David Harrison, Habib Samady

“…Unfortunately, she developed fatal respiratory failure. Upon autopsy, the bladder was found to contain polyps of invasive squamous cell carcinoma, similar in morphology to the tumor mass in the heart. …”
Get full text

Ceftriaxone-Induced Immune Hemolytic Anemia: In Vitro Reversal with Peptide Inhibitor of Complement C1 (PIC1) by Kenji M. Cunnion, Lisa M. Feagin, Michael F. Chicella, Cortney L. Kaszowski, Pamela S. Hair, Jessica Price, William C. Owen

“…She rapidly developed respiratory failure and anemia. Her direct antiglobulin test was positive for IgG and C3. …”
Get full text

Diffuse Alveolar Hemorrhage in a Patient with Antisynthetase Syndrome by D. A. Vargas-Gutiérrez, F. Solís-Jiménez, K. I. Arias Callejas, L. Cano Cruz, R. Zapata Arenas, A. O. Acero López, P. Puente Rodríguez, S. Velázquez de la Paz

“…The diagnosis of the alveolar hemorrhage was based on the presence of acute respiratory failure, decrease in hemoglobin levels, and observation of macrophages filled with hemosiderin. …”
Get full text

A Fatal Case of Multidrug Resistant Acinetobacter Necrotizing Fasciitis: The Changing Scary Face of Nosocomial Infection by Nupur Sinha, Masooma Niazi, Dmitry Lvovsky

“…A 48-year-old woman with history of HIV, asthma, hypertension, and tobacco and excocaine use presented with acute respiratory failure requiring mechanical ventilation. She was treated for pneumonia for 7 days and was successfully extubated. …”
Get full text

Severe Maternal Morbidity Associated with Systemic Lupus Erythematosus Flare in the Second Trimester of Pregnancy by Matthew J. Blitz, Adiel Fleischer

“…She developed hypoxic respiratory failure and was admitted to the intensive care unit. …”
Get full text

Tetanus Complicated by Dysautonomia: A Case Report and Review of Management by Nishant Sharma, Si Li, Metlapalli Venkata Sravanthi, Dan Kazmierski, Yichen Wang, Amit Sharma, Pragya Dhaubhadel

“…We present an uncommon case of generalized severe tetanus with consequent respiratory failure requiring mechanical ventilation, which was associated with dysautonomia. …”
Get full text

Rapidly Progressing Refractory Hodgkin Lymphoma: A Case Report and a Possible Explanation by Ádám Jóna, Gábor Irsai, Sándor Barna, Gábor Méhes, Árpád Illés, László Váróczy

“…Unfortunately the patient developed acute kidney and respiratory failure and died after 6 months of treatment. …”
Get full text

Placental Findings in Lysosomal Storage Disease Diagnosis: A Case Report of Galactosialidosis by Sasha Libbrecht, Francois Eyskens, Sabine Declercq, Cecile Colpaert

“…A third child of consanguineal parents showed several dysmorphic features and a complicated neonatal period with eventual demise in the early postneonatal period due to respiratory failure. An LSD was suspected based on clinical presentation, urine metabolite excretion, skeletal radiograph, and vacuolisation in lymphocytes and placental tissues on, respectively, blood smear and routine histological examination. …”
Get full text

Crushing Stones: Mechanical, Intracorporeal and Extracorporeal Lithotripsy in the Clearance of Common Bile Duct Lithiasis by Claude Liguory, Jean Francois Lefebevre, Didier Bonnel, Gary C Vitale

“…There were four treatment failures, with one patient death due to cholangitis and respiratory failure. In summary, mechanical lithotripsy is an effective and safe treatment modality but has a high failure rate. …”
Get full text

Time to intubation with McGrath™ videolaryngoscope versus direct laryngoscope in powered air-purifying respirator: a randomised controlled trial by Qing Yuan Goh, Sui An Lie, Zihui Tan, Pei Yi Brenda Tan, Shin Yi Ng, Hairil Rizal Abdullah

“…However, there is no evidence that VL reduces time to tracheal intubation, and this is important for COVID-19 patients with respiratory failure. Methods: To simulate intubation of COVID-19 patients, we randomly assigned 28 elective surgical patients to be intubated with either McGrath™ MAC VL or direct laryngoscope (DL) by specialist anaesthetists who donned 3M™ Jupiter™ powered air-purifying respirators (PAPR) and N95 masks. …”
Get full text

Tracheobronchial Foreign Body Aspiration Diagnosed with Electrical Impedance Tomography by Robert D. Guglielmo, Robinder G. Khemani

“…A 19-month-old previously healthy boy was admitted with a clinical diagnosis of respiratory failure secondary to bronchiolitis. Chest X-ray showed bilateral lung hyperinflation. …”
Get full text

Severe Respiratory Distress in a Child with Pulmonary Idiopathic Hemosiderosis Initially Presenting with Iron-Deficiency Anemia by A. Potalivo, L. Finessi, F. Facondini, A. Lupo, C. Andreoni, G. Giuliani, C. Cavicchi

“…A 6-year-old boy was admitted to the hospital with a severe iron-deficiency anemia, but he later developed severe acute respiratory failure and hemoptysis requiring intubation and mechanical ventilation. …”
Get full text

Invasive Pulmonary Aspergillosis with Disseminated Infection in Immunocompetent Patient by Gabriel Moreno-González, Antoni Ricart de Mesones, Rachid Tazi-Mezalek, Maria Teresa Marron-Moya, Antoni Rosell, Rafael Mañez

“…In the first 24 hours she developed an acute respiratory failure with new radiographic infiltrates requiring Intensive Care Unit admission. …”
Get full text

Asymptomatic Pulmonary Artery Intimal Sarcoma with Chest Wall Metastasis as an Initial Manifestation: An Autopsy Case by Tomoo Kakimoto, Mamoru Sasaki, Shojiroh Morinaga, Robert Nakayama, Naoto Minematsu

“…He was scheduled to receive supportive care, but died of respiratory failure 1 year from the first visit. An autopsy revealed the pleomorphic sarcoma occupying the entire lumen of the right pulmonary artery with the only site of extrapulmonary metastasis in the chest wall. …”
Get full text

Can Diaphragm Dysfunction Be Reliably Evaluated with Pocket-Sized Ultrasound Devices in Intensive Care Unit? by Gul Gursel, Kamil Inci, Zenfira Alasgarova

“…Besides, it would also be useful in differential diagnosis of dyspnea and respiratory failure. The aim of this study is to evaluate usefulness and accuracy of pocket-sized ultrasound devices (PSDs) in assessment of DD in intensive care unit (ICU) patients in comparison with standard ultrasound devices (SD). …”
Get full text

Our Experience of Managing Central Airway Tumors: Anesthesia Perspectives by Thushara Madathil, Devika Poduval, Tony Jose, Nagarjuna Panidapu, Don Jose, Tinku Joseph, Praveen Kumar Neema

“…Airway tumors with >75% airway lumen compromise are the sickest and may present in respiratory failure. We found that in these patients, maintaining spontaneous ventilation, avoidance of general anesthesia, and muscle relaxation are the keys to management. …”
Get full text

Herpes Simplex Virus Hepatitis in an Immunocompetent Adult: A Fatal Outcome due to Liver Failure by Rachel A. Poley, Jaime F. Snowdon, Daniel W. Howes

“…She progressed to respiratory failure requiring intubation and mechanical ventilation. …”
Get full text