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  1. 141

    Risk of All-Cause Mortality in US Adults With Preserved Ratio Impaired Spirometry: An Observational Study by Xiao S, Ou J, Qiu W, Ye C, Li N, Chen S, Lai Y, Deng Z, Wu F, Shen Y

    Published 2025-02-01
    “…Shan Xiao,1,&ast; Jie Ou,2,&ast; Wangli Qiu,3,&ast; Chunxin Ye,1 Na Li,1 Sida Chen,1 Yuting Lai,1 Zhishan Deng,4 Fan Wu,4 Yan Shen1 1Department of Pulmonary and Critical Care Medicine, Shenzhen Longgang District Central Hospital, Shenzhen, People’s Republic of China; 2State Key Laboratory of Respiratory Disease, Guangzhou Chest Hospital, Guangzhou, People’s Republic of China; 3Department of Respiratory and Critical Care Medicine, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, People’s Republic of China; 4State Key Laboratory of Respiratory Disease & Guangzhou Institute of Respiratory Health & National Clinical Research Center for Respiratory Disease & National Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yan Shen, Email drshenyan2022@163.com Fan Wu, Email wu.fan@vip.163.comBackground: Preserved ratio impaired spirometry (PRISm) is defined as forced expiratory volume in one second (FEV1)/forced vital capacity (FVC)≥ 0.70 and FEV1< 80% predicted. …”
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  2. 142

    Efficacy of Intravenous Tenecteplase Bridge Thrombectomy for Recurrent Ischemic Stroke Within 3 Months: A Case Report by Liu C, Liu J, Ren H, Xu Y, Liu W

    Published 2025-02-01
    “…Cuicui Liu, Junyan Liu, Huiling Ren, Yuzhu Xu, Wanhu Liu Department of Neurology, The Third Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of ChinaCorrespondence: Wanhu Liu, Department of Neurology, The Third Hospital of Hebei Medical University, 139 Ziqiang Road, Shijiazhuang, 050000, People’s Republic of China, Email 22034101068@stu.hebmu.edu.cnAbstract: In the previous guideline recommendations, patients who have had a stroke within 3 months are excluded from intravenous thrombolysis (IVT) regimens. …”
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  3. 143

    Gut Microecological Prescription: A Novel Approach to Regulating Intestinal Micro-Ecological Balance by Zhu L, Yang X

    Published 2025-02-01
    “…Lingping Zhu,1,2 Xuefeng Yang1 1The Affiliated Nanhua Hospital, Department of General Practice, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, People’s Republic of China; 2School of Public Health, Fudan University, Shanghai, 200433, People’s Republic of ChinaCorrespondence: Lingping Zhu, Email zlp597@aliyun.comAbstract: The intestinal microecology is comprises intestinal microorganisms and other components constituting the entire ecosystem, presenting characteristics of stability and dynamic balance. …”
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  4. 144
  5. 145

    Stem Cell Transplantation for Ovarian Cancer Patient with Associated Myelodysplasia After Maintenance Therapy with Olaparib: A Case Report by Linn Z, Gu Z, Wang L, Cai S

    Published 2025-02-01
    “…Zeyar Linn,1 Zhongyi Gu,1 Libing Wang,2 Shengyun Cai1 1Department of Obstetrics and Gynecology, The First Affiliated Hospital of Naval Medical University (Changhai Hospital), Naval Medical University, Shanghai, People’s Republic of China; 2Department of Hematology, The First Affiliated Hospital of Naval Medical University (Changhai Hospital), Naval Medical University, Shanghai, People’s Republic of ChinaCorrespondence: Shengyun Cai, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Naval Medical University (Changhai Hospital), Naval Medical University, 168 Changhai Road, Shanghai, 200433, People’s Republic of China, Email caicai24@126.comAbstract: Ovarian cancer remains a significant cause of morbidity and mortality in women worldwide. …”
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  6. 146

    Exploring the Causal Relationship and Molecular Mechanisms Between Fasting Insulin and Androgenetic Alopecia: A Mendelian Randomization Study with Bioinformatics Analysis by Ding X, Bai Z, Wang W, Gu Y, Li Z, Fan Y

    Published 2025-02-01
    “…Xiaoxia Ding,1,&ast; Zicheng Bai,2,&ast; Wenwen Wang,2 Yu Gu,3 Zhiming Li,2 Yibin Fan1 1Center for Plastic & Reconstructive Surgery, Department of Dermatology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Dermatology and Venereology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Dermatology, The First People’s Hospital of Aksu Prefecture, Aksu, XinJiang, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yibin Fan, Email fanyibin@hmc.edu.cn; Zhiming Li, Email zhi-mingli@wmu.edu.comBackground: Prior studies have suggested a significant connection between fasting insulin (FI) and androgenetic alopecia (AGA), but the exact cause of this connection and underlying molecular mechanism has not been clarified. …”
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  7. 147

    Silica Nanoparticles Loaded With Selenium Quantum Dots Reduce Myocardial Ischemia-Reperfusion Injury by Alleviating Ferroptosis and Mitochondrial Dysfunction by Li T, Yang B, Liu X, Shi D, Wang Z, Chen Y, Shen C

    Published 2025-02-01
    “…Taixi Li,1,&ast; Boshen Yang,1,&ast; Xijian Liu,2 Dongmei Shi,1 Zhixiang Wang,1 Yizhi Chen,1 Chengxing Shen1 1Department of Cardiology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People’s Republic of China; 2School of Chemistry and Chemical Engineering, Shanghai Frontiers Science Research Center for Druggability of Cardiovascular Noncoding RNA, Shanghai Engineering Technology Research Center for Pharmaceutical Intelligent Equipment, Shanghai University of Engineering Science, Shanghai, 201620, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Chengxing Shen, Department of Cardiology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People’s Republic of China, Email shencx@sjtu.edu.cnPurpose: Myocardial ischemia-reperfusion (IR) injury, a significant challenge in cardiovascular treatment, is primarily driven by ferroptosis and mitochondrial dysfunction. …”
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  8. 148

    Dynamic Impact of the Sleep Disorder, Depression and Anxiety on the Cognitive Function in the First-Episode Depressive Patients by Zhang W, Zhou N, Li J

    Published 2025-02-01
    “…Wenqiong Zhang,1,&ast; Nan Zhou,1,&ast; Jie Li2 1Department of Mood Disorders, Tianjin Anding Hospital, Tianjin City, 300222, People’s Republic of China; 2The Dean’s Office, Tianjin Anding Hospital, Tianjin City, 300222, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jie Li, The Dean’s Office, Tianjin Anding Hospital, No. 13, Liulin Road, Hexi District, Tianjin City, 300222, People’s Republic of China, Tel +86-022-88188326, Email jielimd859@163.comBackground: Sleep disorder is closely related to depressive and anxious status as well as cognitive symptoms.Materials and Methods: A total of 173 cases with the first-episode major depressive disorder (MDD) were involved in this study. …”
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  9. 149

    Injectable Nanocomposite Hydrogel for Accelerating Diabetic Wound Healing Through Inflammatory Microenvironment Regulation by Chen Y, Li Y, Song H, Liu X, Zhang H, Jiang J, Liu H, Zhuo R, Cheng G, Fang J, Xu L, Qi Y, Sun D

    Published 2025-02-01
    “…Yuhui Chen,1,&ast; Ying Li,1,&ast; Haoning Song,1,&ast; Xiaochun Liu,1 Hongan Zhang,1 Jiaxin Jiang,2 Hongsheng Liu,2 Ribo Zhuo,1 Guoyun Cheng,1 Jia Fang,1 Lei Xu,1 Yong Qi,1 Dawei Sun1 1Department of Orthopedics and Traumatology, The Affiliated Guangdong second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, 510315, People’s Republic of China; 2Guangdong Huayi Biomedical Science and Technology Center, Guangzhou, Guangdong, 511450, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Lei Xu, Department of Orthopedics and Traumatology, Guangdong second Provincial General Hospital of Jinan University, No. 466 Xingang Middle Road, Haizhu District, Guangzhou, Guangdong, People’s Republic of China, Email orthoxl@163.com Dawei Sun, Department of Orthopedics and Traumatology, Guangdong second Provincial General Hospital of Jinan University, No. 466 Xingang Middle Road, Haizhu District, Guangzhou, Guangdong, People’s Republic of China, Email sundw@gd2h.org.cnBackground: A paramount issue in the realm of chronic wound healing among diabetic patients is the pervasive inflammatory response that persistently thwarts angiogenesis, thereby precipitating protracted delays in the healing process of such wounds. …”
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  10. 150
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  13. 153

    Efficacy of Group O Washed Red Blood Cell Transfusion on Vital Signs and Hematologic Stability in Trauma Patients With Different Blood Types by Gou XJ, Li LF, He XL, Chen X, Yu AY, Tian WY

    Published 2025-02-01
    “…Xian-Juan Gou,1 Lin-Fei Li,1 Xiao-Li He,1 Xi Chen,2 An-Yong Yu,1 Wei-Yan Tian1 1Department of Emergency, Affiliated Hospital of Zunyi Medical University, Zunyi City, Guizhou Province, 563000, People’s Republic of China; 2School of Nursing, Zunyi Medical University, Zunyi City, Guizhou Province, 563000, People’s Republic of ChinaCorrespondence: Wei-Yan Tian, Department of Emergency, Affiliated Hospital of Zunyi Medical University, Zunyi City, Guizhou Province, 563000, People’s Republic of China, Tel +86 19184321912, Email 907359734@qq.comObjective: To comprehensively assess the impact of emergency transfusion of group O washed red blood cells on the vital signs and hematological parameters of patients with severe trauma and to analyze the differential responses among different blood types, thereby providing valuable evidence for optimizing transfusion strategies.Methods: A retrospective analysis was conducted on the clinical data of patients with severe trauma who underwent emergency transfusion in the hospital’s emergency department from April 2023 to March 2024. …”
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  14. 154

    Network Pharmacology and Experimental Validation of the Therapeutic Effect of Baji Capsule on LPS-Induced Osteoporosis by Li Q, Li D, Tian C, Liu X, Wang H, Liu H

    Published 2025-02-01
    “…Qian Li,1 Dinglin Li,1 Ciqiu Tian,2 Xiangjie Liu,1 Hui Wang,1 Hao Liu1 1Liyuan Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Tongji Medical College of Science and Technology, Wuhan, People’s Republic of China; 2Hubei University of Chinese Medicine, Wuhan, People’s Republic of ChinaCorrespondence: Hao Liu, Liyuan Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology, Tongji Medical College of Science and Technology, Wuhan, People’s Republic of China, Email 729481937@qq.comPurpose: Osteoporosis is a common skeletal disease characterized by impaired bone microarchitecture, decreased bone mineral density and increased bone fragility, leading to a heavy physical and economic burden due to its greatly increased risk of fracture. …”
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  15. 155

    Association Between Dietary Inflammatory Index and Triglyceride Glucose-Body Mass Index with Iron Deficiency in Reproductive Age Women: Evidence from NHANES 2005-2018 by Ding J, Xu Z, Liang R, Xie S

    Published 2025-02-01
    “…Jia Ding,1,&ast; Zhehao Xu,2,&ast; Ruiyun Liang,3 Shuangfeng Xie1 1Department of Hematopathology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China; 2Department of General Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China; 3Department of Respiratory Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Shuangfeng Xie, Email xiesf@163.comBackground & Aims: There is a growing focus on the role of dietary factors and metabolic conditions in the evolution and progression of iron deficiency (ID), yet few studies have examined the underlying mechanisms. …”
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  16. 156

    Permeability-Enhancing and Protective Effect on Small Intestine of Punicic Acid in Different Forms and Their Nanoemulsions With Low Toxicity by Duan D, Xie H, Jiang J, Yang P, Guo Z, Guo X, Chen X, Yao Q

    Published 2025-02-01
    “…Dongyan Duan,1,&ast; Hua Xie,2,&ast; Jiayi Jiang,1 Ping Yang,1 Zhiyuan Guo,2 Xiaoqiang Guo,1 Xingyu Chen,1 Qian Yao1 1Key Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu, 610106, People’s Republic of China; 2Sichuan Provincial Institute for Drug Control and Research, Chengdu, 610000, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Qian Yao, School of Pharmacy, Chengdu University, Shiling Town, Longquan District, Chengdu, Sichuan Province, 610106, People’s Republic of China, Email yaoqian@cdu.edu.cnPurpose: Most absorption enhancers boost the oral absorption of drugs via increasing intestinal permeability. …”
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  17. 157

    Beyond Tumors: The Pivotal Role of TRIM Proteins in Chronic Non-Tumor Lung Diseases by Huang X, Yu W, Wei A, Wang X, Chen S

    Published 2025-02-01
    “…Xiangfei Huang, Wen Yu, Aiping Wei, Xifeng Wang, Shibiao Chen Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, People’s Republic of ChinaCorrespondence: Shibiao Chen, Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, 330006, People’s Republic of China, Email Chenlaoshi1111@163.comAbstract: While TRIM proteins are extensively studied in the context of lung tumors, their roles in non-tumor chronic lung diseases remain underexplored. …”
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  18. 158

    Promotion Mechanisms of Stromal Cell-Mediated Lung Cancer Development Within Tumor Microenvironment by Wu S, Hu Y, Sui B

    Published 2025-02-01
    “…Siyu Wu,1,&ast; Yumeng Hu,1,&ast; Bowen Sui2 1Heilongjiang University of Chinese Medicine, Harbin, People’s Republic of China; 2First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Bowen Sui, Email suibowen79@126.comAbstract: Lung cancer, with its high incidence and mortality rates, has garnered significant attention in the medical community. …”
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  19. 159

    Clinical Characteristics of 31 Patients with Chest Pain Variant Asthma by Mao W, Gao Y, Sun W, Li J, Wang J, Wang Z, Zhang L, Huang K

    Published 2025-02-01
    “…Wenping Mao,1 Yanli Gao,2 Wanlu Sun,1 Jie Li,1 Jing Wang,1 Zhaomei Wang,1 Liming Zhang,1 Kewu Huang1 1Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Kewu Huang, Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China, Tel +86-010-85231167, Email kewuhuang@126.comPurpose: Asthma is a major public health challenge in China. …”
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  20. 160

    Quzhou Aurantii Fructus Flavonoids Ameliorate Inflammatory Responses, Intestinal Barrier Dysfunction in DSS-Induced Colitis by Modulating PI3K/AKT Signaling Pathway and Gut Microbi... by Wang H, Huang W, Pan X, Tian M, Chen J, Liu X, Li Q, Qi J, Ye Y, Gao L

    Published 2025-02-01
    “…Haiou Wang,1 Wenkang Huang,1 Xiaoya Pan,1 Meizi Tian,1 Jiahui Chen,1 Xiaotong Liu,1 Qin Li,1 Jianhua Qi,2 Yiping Ye,1 Lijuan Gao1 1School of Pharmacy, Hangzhou Medical College, Hangzhou, 310013, People’s Republic of China; 2College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, People’s Republic of ChinaCorrespondence: Lijuan Gao; Yiping Ye, Hangzhou Medical College, 182 Tianmushan Road, Hangzhou, Zhejiang, 310013, People’s Republic of China, Email gaolijuan04141002@126.com; yeyiping2005@163.comPurpose: To explore the protective effect and underlying mechanism of Quzhou Aurantii Fructus flavonoids (QAFF) on Ulcerative colitis (UC).Methods: The constituents of QAFF were accurately determined by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). …”
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